• 제목/요약/키워드: initial defect

검색결과 273건 처리시간 0.033초

항경련제 Vigabatrin이 시야에 미치는 영향 (Assessment of the Relationship between Vigabatrin and Visual Field Defect in Children)

  • 정사준;정용환;조의현
    • Clinical and Experimental Pediatrics
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    • 제45권12호
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    • pp.1546-1550
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    • 2002
  • 목 적: 본 저자들은 VGB과 시야결손과의 관련성을 알기 위해 본 연구를 시행하였다. 방 법: 간질로 진단 받고 VGB을 추가 복용으로 치료를 시행한 환아 중 발달 연령이나 인지 연령이 8세 이상인 환아 78명을 대상으로 하였다. 시야검사는 Humphrey 자동 시야측정계로 시행한 후 결과가 의심이 되면 Goldman 시야측정계로 검사를 즉시 다시 시행하였으며, 이들은 다시 6개월 후에 재검을 실시하였다. 결 과 : 본 연구에서는 78명 중 5명에게 의증이 있었으나 재검시 다시 정상으로 나와 시야결손이 있는 환아는 없었다. 결 론: 본 조사에서 VGB은 시야결손을 일으키는 약물로 나타나지는 않았다. VGB의 시야결손으로 사용에 제한을 두기보다 다른 약으로 조절이 되지 않는 부분발작과 영아연축의 치료에 초기 선택 약물로 조심스럽게 사용하면 무방할 것으로 생각되어진다. 이와 함께 시야결손의 선별검사가 추천되며, VGB을 복용하는 소아에게 있어 정기적인 검사가 필요하겠다.

ISO/TS16949 APQP Zero Defect 달성을 위한 개발기법의 적용사례에 관한 연구 (The ISO/TS16949 the research regarding the application instance of the development technique for a APQP zero defect attainment)

  • 문찬오
    • 경영과정보연구
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    • 제22권
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    • pp.211-229
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    • 2007
  • The ISO/TS16949 APQP goal of defect prevention and decrease of spread waste, is the customer satisfaction which leads a continuous improvement and profit creation. The quality expense where the most is caused by but with increase of production initial quality problem occurrence is increasing to is actuality. Like this confirmation amendment. with the problem which is forecast in the place development at the initial stage which it does completeness it does not confront not to be able, production phase to be imminent, the problem accumulates and it talks the development shedding of which occurs. In opposition, prediction confrontation. is forecast in development early stage to and it is a structure which does not occur a problem to production early stage. Like this development is a possibility of accomplishing competitive company from production phase. Which attains an goal of, chance cause it leads a APQP activity (common cause) with special cause prevention & detection the connection characteristic of the focus technique against a interaction is important. And the customer requirement satisfaction and must convert a APQP goal of attainment at the key characteristics action step. (1) The Prevention - with Design FMEA application prevention of the present design management/detection, (2) the Detection (prevention/detection) - with Process FMEA application prevention of the present process control/detection, (3) Special Cause - statistical process control (SPC) 4M cause spread removal, (4) Common Cause - statistical process control (SPC) the nothing zero defect which leads the continuous improvement back of spread with application it will be able to attain with application.

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Ventricular septal defect in an Abyssinian cat

  • Lee, Seung-Gon;Moon, Hyeong-Sun;Choi, Ran;Hyun, Changbaig
    • 대한수의학회지
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    • 제48권1호
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    • pp.99-103
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    • 2008
  • A 2-month-old female Abyssinian cat was presented with a severe ascites, cyanosis, and exercise intolerance. Diagnostic studies revealed V/VI holosystolic murmur, sinus tachycardia, generalized cardiomegaly with marked left atrial enlargement and shunt flow between left and right ventricles. Doppler study showed bi-directional shunts in rest and right-to-left shunt after exercise. Based on clinical signs and diagnostic findings, the cat was diagnosed as a reversed ventricular septal defect. The cat was treated with furosemide, nitroglycerine, dobutamine and oxygen supplement. Despite initial improvement of clinical signs after initiation of medical treatment, the cat died of sudden cardiac arrest. Necropsy revealed a perimembranous ventricular septal defect.

복부손상으로 생긴 탈장에 Prolene Mesh를 이용한 수술 1례 (Traumatic Abdominal Wall Hernia (TAWH): Repair by using a Prolen Mesh)

  • 박승연;정민
    • Journal of Trauma and Injury
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    • 제22권1호
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    • pp.119-122
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    • 2009
  • Traumatic abdominal wall hernia after blunt abdominal trauma is rare. The prevalence of traumatic abdominal wall hernia in published series is approximately 1%. Recently, by the use of computed tomography has increased the number of occult traumatic abdominal wall hernias (TAWH). A 47-year-old woman presented to the emergency room soon after a traffic accident. She was fully conscious and complained of diffuse, dull, abdominal pain. She had a seat belt on at the time of the accident. Initial computed tomography showed that the lower left abdominal wall had a defect and that a part of the small bowel had herniated through the defect. During the operation, we made an incision at the defect site and confirmed the defect. The defect size was about $15{\times}5cm$. The muscle layers were repaired in layers with absorbable sutures. Prolen mesh was layed down and fixed on the site of the repaired muscle defect. After 6 months, hernia had not recurred, and no weakness of the repaired abdominal wall layers was identified. The patient's postoperative body functions were normal.

The Oxygen Potential of Urania Nuclear Fuel During Irradiation

  • Park, Kwang-Heon
    • The Korean Journal of Ceramics
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    • 제4권2호
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    • pp.72-77
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    • 1998
  • A defect model for UO$_2$ fuel containing soluble fission products was devised based on the defect structure of pure and doped uranias. Using the equilibrium between fuel solid-solution and fission-products and the material balance within the fuel, a tracing method to get the stoichiometry change of urania fuel with burnup was made. This tracing method was applied to high burnup urania fuel and DUPIC fuel. The oxygen potential of urania fuel turned out to increase slightly with burnup. The stoichiometry change was calculated to be negligible due to the buffering role f Mo. The oxygen potential of DUPIC fuel out to be sensitive to the initial chemical state of Mo in the fuel.

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대동맥 결손증 (Type A) 의 외과적 치험 (Surgical Repair of Interruption of the Aortic Arch[Type A] -A Report of 5 Cases-)

  • 조범구
    • Journal of Chest Surgery
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    • 제21권4호
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    • pp.665-671
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    • 1988
  • Between 1981 and 1987, five patients with an interruption of the aortic arch were operated upon. All had a ventricular septal defect and a patent ductus arteriosus as associated anomalies. A two-stage procedure was employed in these cases, the initial procedure being repair of the interrupted arch, ligation of the patent ductus arteriosus, banding of the main pulmonary artery and a lung biopsy which was followed, 5 to 49 months later, by the repair of the ventricular septal defect. Four patients completed the two-stage procedure with one postoperative mortality. The remaining patient is yet to complete the second stage procedure.

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안정적인 사출성형조건의 탐색을 위한 지원시스템 (A Support System for Searching Robust Injection Molding Condition)

  • 김보현;백재용;이일랑
    • 산업공학
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    • 제18권1호
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    • pp.73-81
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    • 2005
  • Injection molding has been widely used in producing plastic parts in large quantities. However, its productivity mainly depends on the expertise and experience of skilled workers because of the difficulty and complexity to determine a robust injection molding condition which is not influenced by the minor operational variation of an injection molding machine and produces good parts continuously. This study analyzes the defect types of the parts and proposes a support system to assist users in determining the robust process condition. The support system calculates the start condition from the information of an injection mold, the injection molding machine, the resin used, and the part. Through the iterative step which updates the condition using the defect information of the part tested, users can obtain the initial condition which produces the part without any problem for the first time. The support system also assists users in obtaining the robust condition from the initial condition using the technique of experimental design. To prove the validity of the support system, this study implements it in the control panel of the injection molding machine.

강판의 초기不整이 용접변형.잔류응력에 미치는 영향 (Effect of Initial Defects on Welding Deformation and Residual Stress)

  • 박정응
    • Journal of Welding and Joining
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    • 제17권4호
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    • pp.76-84
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    • 1999
  • The residual stress generated when the steel plates were produced, did not influence on the out-of-plane deformation and residual stress generated by welding. When the initial deflection shape was a concave(Type I), the out-of-plane deformation became the same shape as that of the initial deflection and its magnitude became small. When the initial deflection made a winding in the welding direction(Type III), the out-of-plane deformation became large in the plate width. The initial deflection shape did not influence on residual stress and plastic strain produced by welding.

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Promoted Bone Regeneration by Nanoparticle-Type Sustained Release System of BMP-2 in Hydrogel

  • Chung, Yong-Il;Lee, Seung-Young;Tae, Gi-Yoong;Ahn, Kang-Min;Jeon, Seung-Ho;Lee, Jong-Ho
    • 한국고분자학회:학술대회논문집
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    • 한국고분자학회 2006년도 IUPAC International Symposium on Advanced Polymers for Emerging Technologies
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    • pp.264-264
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    • 2006
  • The nanoparticle-hydrogel complex as a new bone defect replacement matrix, which is composed of the nanoparticles for the sustained release of BMP and the hydrogel for filling the bone defect site and playing a role as a matrix where new bone can grow, is presented. In vivo evaluation of bone formation was characterized by soft X-ray, MT staining, and calcium assay, based on the rat calvarial critical size defect model. The effective bone regeneration was achieved by the BMP-2 loaded nanoparticles in fibrin gel, compare to bare fibrin gel, the nanoparticle-fibrin gel complex without BMP-2, or the BMP-2 in fibrin gel, in terms of the new bone area and the gray level in X-ray, the bone marrow are, and the calcium content in the initial defect site. These findings suggest that the BMP-2 loaded nanoparticle-fibrin gel complex can a promising candidate for a new bone defect replacement matrix.

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영아기의 심실중격결손에 대한 이라완전교정술과 단계교정술의 비교 (Surgical Management of Ventricular Septal Defect in Infancy)

  • 김병호
    • Journal of Chest Surgery
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    • 제27권1호
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    • pp.24-30
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    • 1994
  • Eighteen infants with a large ventricular septal defect[VSD] underwent primary surgical repair from January 1986 to December 1992. Operation was done because of failure to thrive, medically intractable heart failure, recurrent pneumonia, increased pulmonary vascular resistance[PVR]. Four patients[22.2%] died in the early postoperative period. Relief of heart failure and normalization of growth and weight gain was evident in all survivor. There was no late postoperative death. The results of primary surgical repair of VSD in infancy are compared with those of palliative pulmonary artery banding[PAB] and of VSD closure after PAB. Twenty-seven patients with isolated VSD or with VSD associated with atrial septal defect, patent ductus arteriosus, or coarctation of the aorta underwent initial palliative PAB. There were 3 early postoperative deaths[11.1%]. Severe elevation of PVR persisted in two patients. Closure of VSD and pulmonary artery debanding was done in twenty patients, with 2 early postoperative deaths[10.0%]. Placement of the PAB too close to the pulmonary annulus necessitated trasannular patching in one patient, but any problem caused by migration of the band was not developed. It is concluded that primary surgical repair of VSD in infancy is reasonable and that PAB is indicated only for those patients less than 6 months old with a complicated defect or in an emergency situation.

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