• Asian Pacific Journal of Cancer Prevention
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• 제13권5호
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• pp.2179-2184
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• 2012

Introduction and aim: To compare reproductive factor influence on patients with pathological diagnosed malignant and benign tumor in the Breast Department, The First Peoples' Hospital of Kunming in Yunnan province, China. Methods: A hospital-based case-control study was conducted on 263 breast cancer (BC) cases and 457 non-breast cancer controls from 2009 to 2011. The cases and controls information on demographics, medical history, and reproductive characteristics variables were collected using a self-administered questionnaire and routine medical records. Histology of breast cancer tissue and benign breast lesion were documented by pathology reports. Since some variables in data analysis had zero count in at least one category, binomial-response GLM using the bias-reduction method was applied to estimate OR's and their 95% confidence intervals (95% CI). To adjust for age and menopause status, a compound variable comprising age and menopausal status was retained in the statistical models. Results: multivariate model analysis revealed significant independent positive associations of BC with short menstrual cycle, old age at first live birth, never breastfeeding, history of oral contraception experience, increased number of abortion, postmenopausal status, and nulliparity. Categorised by age and menopausal status, perimenopausal women had about 3-fold and postmenopausal women had more than 5-fold increased risk of BC compared to premenopausal women. Discussion and Conclusion: This study has confirmed the significant association of BC and estrogen related risk factors of breast cancer including longer menstrual cycle, older age of first live birth, never breastfeeding, nulliparity, and number of abortions more than one. The findings suggest that female hormonal factors, especially the trend of menopause status play a significant role in the development of BC in Yunnan women.

• Asian Pacific Journal of Cancer Prevention
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• 제15권14호
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• pp.5879-5882
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• 2014

High-risk (HR) human papillomavirus (HPV) testing is important in cervical cancer screening for triage colposcopy. The objective of the study was to evaluate the prevalence of HR HPV infection with different cervical cytological features among women undergoing health examination. A total of 2,897 women were retrospectively evaluated between May 2011 to December 2011. DNA was extracted from residual specimens collected during routine liquid-based cytology tests at the National Cancer Institute. Overall, HR HPV prevalence was 9.3% including 1.6% of HPV-16 and 0.4% of HPV-18. Of all 270 HPV positive samples, 211 (78.1% were HR-HPV non 16/18; 47 (17.4%) were HPV-16 and 12 (4.4%) were HPV-18. The prevalence of HPV infection was similar in all age groups, although a higher rate was observed in women age 31-40 years. Among women with normal cytology, HR HPV positive were found in 6.7%. In abnormal cytology, HR HPV were found 46.7% in atypical squamous cells (ASC), 54.8% in low-grade squamous intraepithelial lesions (LSIL) and 80.0% in high-grade squamous intraepithelial lesions (HSIL). HPV-16 was detected in 8.6%, 6.4% and 12.0% of ASC, LSIL and HSIL, respectively. The results of this study provide baseline information on the HPV type distribution, which may be useful for clinicians to decide who should be monitored or treated more aggressively.

• 보건행정학회지
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• 제11권1호
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• pp.131-152
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• 2001

Public health system and public health practice have changed over the past decades as the result of social and epidemiologic changes. New public health concept emphasizes leadership, strategical thinking, systematic planning and effective performance to identify and solve complex health problem In Korea, the role of Health Center has been expanded rapidly. However there is strong suspicion that Health Center can achieve their mission. This paper aims at understanding what is the needed functions of Health Center and which of its aspects needs improvement. The main results of this study are summarizes as follows. District Health Law does not address the core functions of Health Center. The staffs of Health Center have difficulties in prioritizing their services. The recent attempt to restructure Health Center and change delivery pattern of public health services ended with only limited success. To effectively confront threats to the public's health, the three major function of Health Center must be ${\circled}1$ modifying individual behavior and lifestyle, ${\circled}2$ improving social and economic conditions, and ${\circled}3$ reforming health policies. Better results do not come from setting new functions only; they come from understanding and improving the processes that will then leads to better outcome. We recommend that policy-makers focus economic evaluation of public health programs, building and spreading of the scientific evidence of programs, linkage of public health research and public health program. The criteria of delegation of public health service to private sector is urgently needed. Making community health information data available on a routine basis to providers, managers and researchers of public health services helps promote the efficiency of the overall operation of public health system.

• Smart Structures and Systems
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• 제6권3호
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• pp.197-209
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• 2010

The structural state of a bridge is currently examined by visual inspection or by wired sensor techniques, which are relatively expensive, vulnerable to inclement conditions, and time consuming to undertake. In contrast, wireless sensor networks are easy to deploy and flexible in application so that the network can adjust to the individual structure. Different sensing techniques have been used with such networks, but the acoustic emission technique has rarely been utilized. With the use of acoustic emission (AE) techniques it is possible to detect internal structural damage, from cracks propagating during the routine use of a structure, e.g. breakage of prestressing wires. To date, AE data analysis techniques are not appropriate for the requirements of a wireless network due to the very exact time synchronization needed between multiple sensors, and power consumption issues. To unleash the power of the acoustic emission technique on large, extended structures, recording and local analysis techniques need better algorithms to handle and reduce the immense amount of data generated. Preliminary results from utilizing a new concept called Acoustic Emission Array Processing to locally reduce data to information are presented. Results show that the azimuthal location of a seismic source can be successfully identified, using an array of six to eight poor-quality AE sensors arranged in a circular array approximately 200 mm in diameter. AE beamforming only requires very fine time synchronization of the sensors within a single array, relative timing between sensors of $1{\mu}s$ can easily be performed by a single Mote servicing the array. The method concentrates the essence of six to eight extended waveforms into a single value to be sent through the wireless network, resulting in power savings by avoiding extended radio transmission.

• Mycobiology
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• 제39권3호
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• pp.200-205
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• 2011

Marssonina coronaria associated with apple blotch disease causes severe premature defoliation, and is widely distributed in Korea. Thirteen isolates were collected from orchards located in Gyeongbuk Province from 2005~2007. All isolates displayed over 99.6% and 99.2% sequence similarity to each other in internal transcribed spacer regions and partial sequences of 28S rDNA, respectively. The isolates were phylogenetically closely related to Chinese isolates. Selected isolates did not differ in their pathogenicity. The optimum conditions for fungal growth were $20^{\circ}C$ and pH 6 on peptone potato dextrose agar (PPDA). Peptone and mannose were the best nitrogen and carbon source, respectively. Fungal growth was better on PPDA than on common potato dextrose agar. This study provides valuable information for integrated disease management program and facilitates the routine culturing of M. coronaria.

• Safety and Health at Work
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• 제4권2호
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• pp.100-104
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• 2013

Background: The aim of this study was to assess public and private medical diagnostic laboratories in Nigeria for the presence of biosafety equipment, devices, and measures. Methods: A total of 80 diagnostic laboratories in biosafety level 3 were assessed for the presence of biosafety equipment, devices, and compliance rate with biosafety practices. A detailed questionnaire and checklist was used to obtain the relevant information from enlisted laboratories. Results: The results showed the presence of an isolated unit for microbiological work, leak-proof working benches, self-closing doors, emergency exits, fire extinguisher(s), autoclaves, and hand washing sinks in 21.3%, 71.3%, 15.0%, 1.3%, 11.3%, 82.5%, and 67.5%, respectively, of all laboratories surveyed. It was observed that public diagnostic laboratories were significantly more likely to have an isolated unit for microbiological work (p = 0.001), hand washing sink (p = 0.003), and an autoclave ($p{\leq}0.001$) than private ones. Routine use of hand gloves, biosafety cabinet, and a first aid box was observed in 35.0%, 20.0%, and 2.5%, respectively, of all laboratories examined. Written standard operating procedures, biosafety manuals, and biohazard signs on door entrances were observed in 6.3%, 1.3%, and 3.8%, respectively, of all audited laboratories. No biosafety officer(s) or records of previous spills, or injuries and accidents, were observed in all diagnostic laboratories studied. Conclusion: In all laboratories (public and private) surveyed, marked deficiencies were observed in the area of administrative control responsible for implementing biosafety. Increased emphasis on provision of biosafety devices and compliance with standard codes of practices issued by relevant authorities is strongly advocated.

• 한국콘텐츠학회논문지
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• 제13권7호
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• pp.278-289
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• 2013

본 연구는 노인들의 일상스트레스와 사회적 지지가 심리적 복지감에 미치는 영향을 살펴봄으로써 노인들의 심리적 복지감 증진에 필요한 기초자료를 제공하고자 하였다. 본 연구의 주요연구결과는 다음과 같다. 노인의 심리적 복지감에는 일상적 스트레스 중에 가족관계와 건강문제, 그리고 상실감이 통계적으로 유의미한 부(-)의 영향을 미쳤고, 사회적 지지 중에는 정서적 지지와 친구지지가 유의미한 정(+)의 영향을 미쳤다. 이러한 결과를 볼 때, 노인들의 심리적 복지감 향상을 위해서는 노인들이 일상생활 속에서 겪게 되는 다양한 스트레스에 대처하고, 노인들의 심리적 안정을 위한 다양한 프로그램이 개발 보급되어야 한다. 또한 노인들이 지역사회에서 친구와 함께 할 수 있는 프로그램 개발과 정서적 지지 강화 방안이 마련될 것이다.

• 간호행정학회지
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• 제3권2호
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• pp.81-94
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• 1997

Cardiac catheterization has become a routine diagnostic procedure indicated for evaluation of a wide variety of cardiac conditions. Patients are admitted to the coronary care unit after cardiac catheterization. These conscious patients used to report discomfort in the CCU, but no studies have been done to reduce discomfort induced by bed rest, sand bag on the femoral puncture site and restricted mobility for about 20 hours postprocedure. The main objective of thesis is to provide basic data to nursing on interventions which decrease discomfort perceived by patients in the CCU following cardiac catheterization. The subjects were 79 patients following cardiac catheterization who were admitted to the CCU of a general hospital in Inchon. These patients were divided into a massage-applied group, an exercise-applied group and an contrast group. Questionare was prepared by Lee(1995), and tested for content reliability by item analysis : Cron bach's ${\alpha}$ for the instrument measuring discomfort was. 63. The data were collected from January 25 to May 15, 1996. Analysis of data was done by paired t-test, ANOVA ,SNK test, Chi-square test. The results of the study are summarized as follows : 1. There were no significant differences among a massage-applied group, an exercise-applied group and an contrast group according to general information except religion and admission period. 2. There were found no significant differences among the three groups in the results of pretest (The score of the first : 55.5, the second : 54.3 and the last : 51.6), 3. In the degree of discomfort according to general characteristics were found some significant differences for marital status. But there were no significant differences for sex, age, occupation, number of family, religion, educational status and admission period. 4. There was effect on reduced discomfort with massage or exercise following cardiac catheterization.

• 대한간호학회지
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• 제50권4호
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• pp.523-532
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• 2020

Purpose: The purpose of the study was to compare the effectiveness of multi interventional package (MIP) and lifestyle interventions (LI) on physiological parameters of women with metabolic syndrome, to compare the effectiveness of MIP and LI on biochemical parameters of women with metabolic syndrome and to compare the effectiveness of MIP and LI on socio-psychological parameters of women with metabolic syndrome. Methods: A quasi experimental nonequivalent control group design with two experimental groups and one control group was used to collect data from 60 self-help group women. Samples were selected by multistage sampling. Reflexology foot massage, dietary modification, moderate intensity exercise and structured education were given to MIP group and dietary modification, moderate intensity exercise and structured education were given to LI group for 12 weeks. Control group received routine care. Demographic and clinical data sheets were used to collect basic information. Knowledge was assessed by a knowledge questionnaire. Physiological (weight, body mass index, waist circumference and blood pressure) and biochemical parameters (HDL, triglycerides and FBS) were assessed before and after the intervention. Results: The study found significant change in the physiological and biochemical parameters of metabolic syndrome as well as knowledge among the MIP group and LI group compared to the control group (p <.001). Conclusion: MIP and LI are effective in controlling the parameters of metabolic syndrome. Hence the guidance may be provided to women with metabolic syndrome for adopting necessary lifestyle changes as well as reflexology foot massage to control the physiological and biochemical parameters of metabolic syndrome.

• International Journal of Industrial Entomology and Biomaterials
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• 제28권2호
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• pp.39-50
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• 2014

In order to understand the diversity and genetic relationships of silkworm strains preserved in Korea, we genotyped 78 Bombyx mori strains (Bombycidae: Lepidoptera) originating from Japan, using eight polymorphic microsatellite loci. We obtained per-locus allele numbers ranging from 5 to 16 (with an average value of 9.1), per-locus observed heterozygosity ranging from 0.13 to 1.00, and per-locus polymorphic information content ranging from 0.36 to 0.77, indicating that some loci are highly variable. Phylogenetic analysis with the eight concatenated microsatellite loci showed no clustering based on known strain characteristics and origin. Nineteen strain-specific apomorphic alleles, which discriminated 16 of the 78 silkworm strains, were obtained from eight loci. These strain-specific alleles can thus be utilized for routine discrimination of strains from Japan, without any further typing of other loci. Homozygotes were also observed at some loci (27 of 118 genotypes), which can also be used to discriminate several strains by typing a few loci. These results showed that eight microsatellite loci described herein were sufficiently variable to discriminate among the 78 silkworm strains we examined, and may be useful for future investigations of this economically important species.