• The Journal of the Korea Contents Association
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• v.20 no.10
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• pp.216-232
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• 2020

This research aims to analyze the characteristics of modern public sculptures in Chinese historical and cultural cities, and explore how public sculptures can effectively intervene in historical and cultural elements to show their placeness. In addition, this research provides basic information for the place significance and application of public sculptures. First, the theoretical basis was provided by understanding the concept of historical and cultural city and the concept of Placeness. Second, the related literature and cases were summarized to analyze the expressive characteristics of public sculptures, and the eight factors most related to the place-related characteristics were selected through the evaluation of characteristics from 10 experts. Third, as a case analysis, this study selected 60 cases from 7 magazines with the highest publication volume among public sculptures in China's representative cities, Shanghai, Beijing, and Guangzhou, and finally 15 public sculptures were selected through expert selection. In general, Whether to explore historical and cultural elements or the city's modern humanistic atmosphere, the public sculptures of the three cities all reflect different places.It is the development trend of public sculpture to combine the artistic originality and interaction with the public brought by unique advanced technology, and use the unique historical and human elements of the city to create places that are different from other regions.

• Asian-Australasian Journal of Animal Sciences
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• v.22 no.3
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• pp.313-318
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• 2009

TIAF1 is a TGF-${\beta}$1-induced anti-apoptotic factor that plays a critical role in blocking TNF (tumor necrosis factor) cytotoxicity in mouse fibroblasts and participates in TGF-${\beta}$-mediated growth regulation. In this study, we obtained the full-length cDNA sequence of the porcine TIAF1 gene. Real-time PCR further revealed that the TIAF1 gene was expressed at the highest level in liver and kidney with prominent expressions detected in uterus, and lower levels detected in heart, spleen, lung, stomach, small intestine, skeletal muscle and fat of Large White pigs. Sequence analysis indicated that a 6 base-pair deletion mutation existed in the exon of the TIAF1 gene between Meishan and Large White pigs. This mutation induced deletion of Gln and Val amino acids. PCR-RFLP was used to detect the polymorphism in 394 pigs of a "Large White${\times}$Meishan" $F_{2}$ resource population and four purebred pig populations. The frequencies of the A allele (with a 6 bp deletion) were dominant in Chinese Meishan and Bamei pigs, and the frequencies of the B allele (no 6 bp deletion) were dominant in Large White and Landrace pigs. Association analyses revealed that the deletion mutation had highly significant associations (p<0.01) with meat marbling score of the thorax-waist longissimus dorsi (LD) muscle (MM1) and intramuscular fat percentage (IMF), and significant associations (p<0.05) with carcass length (CL). The results presented here supply evidence that the 6 bp deletion mutation in the TIAF1 gene affects porcine meat quality and provides useful information for further porcine breeding.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.23
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• pp.10277-10280
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• 2015

Background and Aim: Breast cancer (BC) is a heterogeneous disease and cell proliferation markers may help to identify subtypes of clinical interest. We here analyzed the correlation between cell proliferation determined by Ki67 and HG in BC patients undergoing preoperative chemotherapy (PCT). Materials and Methods: We obtained clinical/pathological data from patients with invasive BC treated at our institution from 1999 until 2012. Expression of estrogen receptor (ER), progesterone receptor (PR), epidermal growth factor receptor type 2 (HER2) and Ki67 were determined by immuno-histochemistry (IHC). Clinicopathological subtypes were defined as: Luminal A, ER and/or PR positive, HER2 negative, HG 1 or 2; Luminal B, ER and/or PR positive, HER2 negative or positive and/or HG 3; triple negative (TN), ER, PR and HER2 negative independent of HG; HER2 positive, ER, PR negative and HER2 positive, independent of HG. By using Ki67, a value of 14% separated Luminal A and B tumors, independently of the histological grade. We analyzed correlations between Ki67 and HG, to define BC subtypes and their predictive value for response to PCT. Results: 1,560 BC patients were treated in the period, 147 receiving PCT (9.5%). Some 57 had sufficient clinicopathological information to be included in the study. Median age was 52 years (26-72), with 87.7% invasive ductal carcinomas (n=50). We performed IHC for Ki67 in 40 core biopsies and 50 surgical biopsies, 37 paired samples with Ki67 before and after chemotherapy being available. There was no significant correlation between Ki67 and HG (p=0.237), both categorizing patients into different subtypes. In most cases Ki67 decreased after PCT (65.8%). Only 3 patients had pathologic complete response (cPR). Conclusions: In our experience we did not find associations between Ki67 and HG. Determination of clinicopathological luminal subtypes differs by using Ki67 or HG.

• The Journal of the Korea Contents Association
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• v.13 no.8
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• pp.83-92
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• 2013

Text visualization begins with understanding text itself which is material of visual expression. To visualize any text data, sufficient understanding about characteristics of the text first and the expressive approaches can be decided depending on the derived unique characteristics of the text. In this research we aimed to establish theoretical foundation about the approaches for text visualization by diverse examples of text visualization which are derived through the various characteristics of the text. To do this, we chose the 'Bible' text which is well known globally and digital data of it can be accessed easily and thus diverse text visualization examples exist and analyzed the examples of the bible text visualization. We derived the unique characteristics of text-content, structure, quotation- as criteria for analyzing and supported validity of analysis by adopting at least 2-3 examples for each criterion. In the result, we can comprehend that the goals and expressive approaches are decided depending on the unique characteristics of the Bible text. We expect to build theoretical method for choosing the materials and approaches by analyzing more diverse examples with various point of views on the basis of this research.

• Journal of KIISE
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• v.41 no.9
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• pp.666-673
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• 2014

This paper proposes a scalable face recognition method for unconstrained face databases, and shows a simple experimental result. Existing face recognition research usually has focused on improving the recognition rate in a constrained environment where illumination, face alignment, facial expression, and background is controlled. Therefore, it cannot be applied in unconstrained face databases. The proposed system is face feature extraction algorithm for unconstrained face recognition. First of all, we extract the area that represent the important features(landmarks) in the face, like the eyes, nose, and mouth. Each landmark is represented by a high-dimensional LBP(Local Binary Pattern) histogram feature vector. The multi-scale LBP histogram vector corresponding to a single landmark, becomes a low-dimensional face feature vector through the feature reduction process, PCA(Principal Component Analysis) and LDA(Linear Discriminant Analysis). We use the Rank acquisition method and Precision at k(p@k) performance verification method for verifying the face recognition performance of the low-dimensional face feature by the proposed algorithm. To generate the experimental results of face recognition we used the FERET, LFW and PubFig83 database. The face recognition system using the proposed algorithm showed a better classification performance over the existing methods.

• Cartoon and Animation Studies
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• s.10
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• pp.1-16
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• 2006

This thesis aims to recall the importance of language in comics by studying comic strips in Korean daily newspapers: the comic strips are analyzed for rhetorical puns in its language text as they representatively show the value and role of language in comics. Moreover, Korean comic strips, as they developed into current affairs comics, acquired a stronger media characteristic of communicating information compared to other genres of cartoons. As a result, comics strips have become a genre where language plays an important role and the words needing to be able to convey the meaning quickly and implicitly. Due to tight control of national authority, the language technique developed into an indirect expression rather than a stronger direct imaging technique. The political oppression of the comic strip paradoxically brought on the rhetorical development in the creative techniques. Based on this analysis, the writer studied the rhetorical puns of the texts Korean comic strips by implementing the classification techniques of rhetoric expressions. As a result, through quotes and analysis of actual comic strips, the writer confirmed that Korean comic strips do actually show tremendously vast rhetorical puns in its language application techniques. The writer was also able to conclude that the rhetorical puns in comics were the force entertaining and impressing the readers, and also acting as the creative principle. Concluding this study, the writer emphasizes that language, not only in comic strips, is a combination of words and images and is also an important factor in all cartoons in general. Thus the thesis proposes that the training of humanistic thoughts and linguistic sensitivity are as important as learning to draw in the creation of cartoons.

• Microbiology and Biotechnology Letters
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• v.45 no.3
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• pp.226-235
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• 2017

Carotenoids such as phytoene, lycopene, and ${\beta}-carotene$ are used as food colorants, animal feed supplements, and for human nutrition and cosmetic purposes. Previously, we reported the isolation of a novel marine bacterium, Kocuria gwangalliensis, which produces a pink-orange pigment. Phytoene desaturase (CrtI), encoded by the gene crtI, catalyzes lycopene formation from phytoene and is an essential enzyme in the early steps of carotenoid biosynthesis. CrtI is one of the key enzymes regulating carotenoid biosynthesis and has been implicated as a rate-limiting enzyme of the pathway in various carotenoid synthesizing organisms. Here, we report the cloning of the crtI gene responsible for lycopene biosynthesis from K. gwangalliensis. The gene consisted of 1,584 bases encoding 527 amino acid residues. The nucleotide sequence of the crtI gene was compared with that of other species, including Kocuria rhizophila and Myxococcus xanthus, and was found to be well conserved during evolution. An expression plasmid containing the crtI gene was constructed (pCcrt1), and Escherichia coli cells were transformed with this plasmid to produce a recombinant protein of approximately 57 kDa, corresponding to the molecular weight of phytoene desaturase. Lycopene biosynthesis was confirmed when the plasmid pCcrtI was co-transformed into E. coli containing the plasmid pRScrtEB carrying the crtE and crtB genes required for lycopene biosynthesis. The results from this study will provide valuable information on the primary structure of K. gwangalliensis CrtI at the molecular level.

• Korean Chemical Engineering Research
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• v.48 no.1
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• pp.80-87
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• 2010

Lignite of low rank coal and petroleum coke of high sulfur content can be high potential energy sources for coal gasification process because of their plentiful supply. The kinetic study of steam gasification has been performed in an atmospheric thermobalance with wood chip, lignite, bituminous, anthracite, pet-coke. The effects of gasification temperature($600{\sim}850^{\circ}C$) and partial pressure of steam(30~90 kPa) on the gasification rate have been investigated. The modified volumetric reaction model was applied to the experimental data to describe the behavior of carbon conversion and to evaluate the needed kinetic parameters. Lignite and wood chip with high volatile content showed high average gasification rates comparing to other fuel and thus they might be proper fuel for gasification processes. The activation energies for wood chip, lignite, bituminous, anthracite, and pet-coke through Arrhenius plot were found to be 260.3, 167.9, 134.6, 82.2, 168.9 kJ/mol, respectively. The expression of apparent reaction rates for steam gasification of various chars have been proposed as basic information for the design of coal gasification processes.

• Polymer(Korea)
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• v.34 no.5
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• pp.474-479
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• 2010

We developed laminated cylindrical scaffolds composed of poly(lactide-co-glycolide)(PLGA) and keratin, and investigated their potential for tissue engineering and disk regeneration. The scaffold was designed to have two parts, i.e. inner cylinder and outer disk, to mimic a natural disk. The outer disk was composed of PLGA and the inner cylinder was prepared using PLGA film or PLGA/keratin hybrid film. In this study, we investigated the effects of keratin on the growth and proliferation of annulus fibrous(AF) cells in the cylindrical scaffolds. Scaffolds containing PLGA/keratin films showed a significantly higher cell proliferation and expression of collagen I and II than the counterpart with PLGA films. Keratin containing scaffolds also exhibited an excellent mechanical strength, demonstrating that keratin influences the proliferation of annulus fibrous cells. The results provide valuable information on PLGA/keratin films for tissue engineered disk regeneration.

• Journal of Chest Surgery
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• v.30 no.7
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• pp.701-707
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• 1997

Although many reseraches have been persued to detect the molecular tumor marker to define the cancer, ideal tumor marker which speak for the characteristics of malignancy and has high sensitivity and specificity is not known. One of the characteristics of the malignant cells is indefinite proliferative potential, in other word, immortality. The expression of telomerase and stabilization of te10meres are con omitant with the attaiunent of immortality in tumor cells; thus the measurement of telomerase activity in clinically obtained tumor samples may provide important information which would be useful as a diagnostic marker to detect immortal cancer cells. Telomerase activity was analyzed in 12 non-small cell . lung cancer cell lines and 41 primary non-small cell lung cancers with the use of a PCR-based assay. All the cell lines and the majority of tumors displayed telomerase activity, but telomerase was not detectable in most of the corresponding pathologically-normal tissues. Telomere length was not correlated with telomerase activity. The present study indicate that measurement of telomerase activity may be useful as a molecular tumor marker in non-small cell lung cancer.