• Title/Summary/Keyword: industrial effect

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Antioxidant and Cellular Protective Effects against Oxidative Stress of Calendula officinalis Flowers Extracts in Human Skin Cells (사람피부세포에서 카렌둘라 꽃 추출물의 항산화 및 산화적 스트레스에 대한 세포보호효과)

  • Xuan, Song Hua;Kim, Ga Yoon;Yu, Ji Yeon;Kim, Jee Won;Yang, Ye Rim;Jeon, Young Hee;Jeong, Yoon Ju;Kim, A Rang;Park, Soo Nam
    • Applied Chemistry for Engineering
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    • v.27 no.6
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    • pp.620-626
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    • 2016
  • In this study, we investigated the total phenolic and flavonoid contents, antioxidant activity and cellular protective effects against oxidative stress on human skin cells in 50% ethanol extract and its fractions of Calendula officinalis (C. officinalis) flowers. We measured the antioxidant effects of 50% ethanol extract and its fractions of C. officinalis flowers on the free radical scavenging activity ($FSC_{50}$), the reactive oxygen species (ROS) scavenging activities ($OSC_{50}$) and the inhibition of intracellular ROS generation in human skin cells. These results showed that the antioxidant effect of the ethyl acetate and aglycone fraction was more than the 50% ethanol extract of C. officinalis flowers. We also investigated the cellular protective activity and the results showed that treatment of the ethyl acetate fraction ($0.05-3.13{\mu}g/mL$) protects human skin cells in a concentration-dependent manner when the skin cell damages were induced by treating them with $H_2O_2$. In addition, the aglycone fraction ($1.56-3.13{\mu}g/mL$) shows cellular protective effects on the UV-induced cell damages in a dose-dependent manner. These results suggest that the fractions of C. officinalis flowers can function as a natural antioxidant agent of cosmetics in human skin cells exposed to oxidative stress by ROS scavenging effects.

Antioxidative and Biological Activites of Extracts of Sweetpotato Tips (고구마 끝순 추출물이 알코올 투여 흰쥐의 항산화 효소계 및 지질과산화에 미치는 영향)

  • Lee, Joon-Seol;Park, Yang-Kyun;Ahn, Young-Sup;Kim, Hag-Sin;Chung, Mi-Nam;Jeong, Byeong-Choon;Bang, Jin-Ki
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.52 no.4
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    • pp.411-420
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    • 2007
  • This study was conducted to increase sweetpotato utilization and to determine the vegetative value of sweetpotato tips by investigating the phenolic compounds, antioxidative effect in oil, electron donating ability, nitrite scavenging effect and ACE inhibition activities. The phenolic compounds present in sweetpotato tips are the gallic, chlorogenic, gentisic, caffeic, couramic and ferulic acid, which are 16-122 times higher compared to other vegetables such as spinach, soybean sprout, and perilla leaves. In each solvent extract, the total phenolic compounds(175.8 mg/g) was composed of 55% EtOAc extraction and 39% BuOH extract, respectively. The results of induction period using the Rancimat method showed that the antioxidant activity of SP tips was higher than the tocopherol or BHT. The relative levels of each solvent extract in SP tips were as follows: EtOAc>BHT>BuOH>Tocopherol>Water>$CHCl_3$>Hexane. The peroxide value was measured every 5 days for 25 days during storage and results showed that the peroxide value, the tips, tuberous root and tocopherol were lower compared to spinach, soybean sprout and perilla leaves. Nitrite scavenging effects were excellent in sweetpotato tips, perilla leaves and soybean sprout, especially, inhibition rate of perilla leaves(72%) were superior to the others. In process of solvent extraction, activity of BuOH and water extractions were the best. ACE inhibition activity in sweetpotato tips was 1.5 times higher than in tuberous roots and $1.9{\sim}3.7$ times higher than in spinach, soybean sprout, perilla leaves.

Industrial potential of domestic Zanthoxylum piperitum and Zanthoxylum schinifolium: Protective effect of both extracts on high glucose-induced neurotoxicity (국내산 초피와 산초의 산업적 활용 가능성: 고당으로 유도된 뇌신경세포 독성에 대한 추출물의 보호 효과)

  • Han, Hye Ju;Park, Seon Kyeong;Kim, Min Ji;An, Jun Woo;Lee, Se Jin;Kang, Jin Yong;Kim, Jong Min;Heo, Ho Jin
    • Korean Journal of Food Science and Technology
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    • v.52 no.3
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    • pp.274-283
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    • 2020
  • This study focused on the in vitro investigation of antioxidant and anti-diabetic activities, along with neuroprotection against high glucose-induced cytotoxicity, in order to evaluate the physiological effects of Zanthoxylum piperitum and Zanthoxylum schinifolium. The highest total phenolic content was measured in the 40% ethanolic extracts of Zanthoxylum piperitum (EZP) and Zanthoxylum schinifolium (EZS). The in vitro EZP antioxidant activity showed a relatively higher ABTS/DPPH radical scavenging activity and malondialdehyde inhibitory effect than that of EZS. The EZP inhibited carbohydrate hydrolysis (α-glucosidase and α-amylase) more efficiently than EZS in anti-diabetic tests. However, EZS showed a more efficient inhibition of advanced glycation end-products formation than EZP. In addition, both EZP and EZS effectively protected human-derived neuronal cells from high glucose-induced cytotoxicity. Finally, the physiological compounds were analyzed using UPLC IMS-QTOF/MSE, and the main EZP (quercetin-3-O-glucoside and 3-caffeoylquinic acid) and EZS (5-caffeoylquinic acid) compounds were identified as phenolic compounds.

A Study on the Pollution of Polycyclic Aromatic Hydrocarbons(PAHs) in the Surface Sediments Around Gwangyang Bay (광양만 주변해역 표층퇴적물에서의 다환방향족탄화수소류(PAHs)의 오염에 관한 연구)

  • You, Young-Seok;Choi, Young-Chan;Cho, Hyeon-Seo
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.13 no.1 s.28
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    • pp.9-20
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    • 2007
  • PAHs(Polycyclic Aromatic Hydrocarbons) are widespread contaminants in the marine environment. They are of mainly anthropogenic origin from urban runoff, oil spill and combustion of fossil fuels. Some PAHs are potentially carcinogenic and mutagenic to aquatic organism The contamination of PAHs in the coastal environments has not been well known yet in Korea. This study was carried out to survey the contamination of PAHs in sediments around Gwangyang bay. The Yeosu petrochemical industrial complex, POSCO(Pohang steel company) and Gwangyang container harbor are located around the bay. PAHs in sediment samples were extracted in soxhlet extractor and were identified and quantified by GC-MS(Gas Chromatography-Mass Spectrometry) TOC(Total Organic carbon) and textural parameters in sediment samples were also analyzed 13 species of PAHs were detected at all of the surface sediments. Total PAHs concentrations in the surface sediments ranged from 171.40 to $1013.54{\mu}g/kg$ dry wt.. In most of the surface sediments, Naphthalene was the highest in the range of 14.08 to $691.39{\mu}g/kg$ dry wt. and Anthracene was the lowest in the range of 0.49 to $22.66{\mu}g/kg$ dry wt.. The correlation coefficients between individual PAHs and Total PAHs in the surface sediments were relatively higher in the low molecular compounds such as Naphthalene and Phenanthrene. In the relationship of the P/A(Phenanthrene/Anthracene) ratio and F/P(Fluoranthene/Pyrene) ratio, P/A ratio was generally above 10 and F/P ratio was shown to be above 1 in all sediment samples. These data indicate that PAHs in sediments around Gwangyang bay seem to be of both pyrolytic and petrogenic origin. Total PAHs in the surface sediments were correlated with TOC and textural parameters. The values of PAHs in the surface and core sediments were lower than the biological effect guidelines.

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Effect of Noise in Human Body (소음이 인체에 미치는 영향)

  • 이영노
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1972.03a
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    • pp.7-8
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    • 1972
  • The effects of noise exposure are of two types: Nonauditory effects and auditory effects. Nonauditory effects of noise exposure are interference with communication by speech, sleeping and emotional behavior. The noise will cause the high blood pressure and rapid pulse, also that decrease the salivation and gastric juice. in experimentaly showed that the Corticoid hormon: Gonatotropic hormone were decrease and Thyrotropic hormoone is increase. Auditory effect of noise exposure. when the normal ear is exposed to noise at noise at hamful intensities (above 90㏈) for sufficiently long periods of time, a temoral depression of hearing results, disappearing after minutes or hours of rest. When the exposure longer or intesity greater is reached the Permanent threshold shift called noise-induced hearing loss. Hearing loss resulting from noise exposure presents legal as well as medical problems. The otologist who examines and evaluates the industrial hearing loss cases must be properly informed, not only concerning the otologic but also about the physical and legal aspects of the problems. The measurement of hearing ability is the most important part of a hearing conservation, both preplacement and periodic follow-up tests of hearing. The ideal hearing conservation program would be able to reduce or eliminate the hazardous noise at its source or by acoustic isolation of noisy working area and two ear protections (plugs and muff type) were developed for personal protection.

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An analysis of the Effects of Software Industry on the Local Economy (소프트웨어산업이 지역경제에 미치는 영향 분석)

  • Kim, Shin-Pyo;Kim, Tea-Yeol;Jung, Su-Jin
    • Journal of Digital Convergence
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    • v.9 no.6
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    • pp.137-151
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    • 2011
  • This dissertation aims to empirically analyze the effect of cultivation of software industry on the local economy through Inter-regional Software Input-Output Analysis. The temporal range of analysis of effect of software industry on the local economy shall be for the year 2005 since analysis is made on the basis of the Regional Industrial Input-Output Table published by the Bank of Korea in 2005, and spatial domain shall be limited to the 16 metropolitan cities and provinces, which are the standards for each administrative zone. Results of analysis of this dissertation are as follows. Firstly, average inverse matrix coefficient of software industry for each region was computed to be 1.6248, which is lower than the average inverse matrix coefficient of 1.7979 for the entire industries. Secondly, among these, inverse matrix coefficient of software industry for each region on other industry within the same region was 0.1794, which is higher than that of entire industries at 0.1382. However, average inverse matrix coefficients of software industry for each region on self-industry within the same region and entire industries in other regions were found to be 1.0119 and 0.4335, respectively, which is lower than those of entire industries at 1.0982 and 0.5616, respectively. Thirdly, domestic produces induced by final demand items of software industry for each region was the highest for Seoul with 17.3309 trillion Korean won, accounting for 81.0% of the total, followed by Gyeonggi with 2.3370 trillion Korean won, 10.9% of the total. Fourthly, distribution ratios of domestic produces induced by final demand items of software industry for each region were found to be 19.1%, 72.1% and 8.8% with respect to the weight of consumption, investment and export, respectively, thereby illustrating very high level of distribution ratios of domestic produces being induced by investment in comparison to the distribution ratios of domestic produces being induced for the entire industries at 47.3%, 19.8% and 32.9%, respectively.

Effect of Cooling Water Capacity on the Engine Performance for Small Diesel Engine (냉각수(冷却水) 용량(容量)이 소형(小型) 디젤기관(機關)의 성능(性能)에 미치는 영향(影響))

  • Myung, Byung Soo;Kim, Soung Rai
    • Korean Journal of Agricultural Science
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    • v.13 no.2
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    • pp.265-278
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    • 1986
  • This study was attempted to improve the thermal efficiency of 6 kW water-cooled diesel engine on power tiller. The engine performance tests were conducted to find out the effect of cooling water capacity of 2700cc, 2800cc, 2900cc, 3000cc, 3100cc on power, brake specific fuel consumption (BSFC), torque, temperature of cooling water and lubricating oil and friction losses of the engine with D. C. dynamometer. The results obtained in the study are summarized as follows: 1. The performance of the engine tested was adequated to Korea Industrial Standard but actual economy power was 10% higher than the labeled rated power of the engine. The BSFC of the engine tested 297.8g/kW-h which is belong a little higher level than hreign products. The temperature of cooling water was $101^{\circ}C$ which is higher than SAE standard ($88^{\circ}C$) 2. The friction losses of engine tested was 3.656 kW at 2200 rpm of rated rpm (piston speed 6.97m/sec) and is higher than those of foreign products. 3. When the cooling water capacity was increased from 2700cc to 3100cc the power output of the engine was increased from 6.7 kW to 7.13 kW at the rate of 6.4% and also the torque of the engine was increased from 28.85 N.m to 30.76 N.m at the rate of 6.39%. 4. When the cooling water capacity was increased from 2700cc to 3100cc, the BSFC was decreased 6.9g/kW-h from 310.9g/kW-h to 304.1g/kW-h, and after one half hour operation with full load, the temperature of cooling water was decreased $13^{\circ}C$ from $101^{\circ}C$ to $88^{\circ}C$ and also the temperature of lubricant oil was decreased $6.4^{\circ}C$ from $76.7^{\circ}C$ to $70.4^{\circ}C$. 5. The mechanical efficiency was increased from 70.08% to 71.08% when the cooling water capacity was increased from 2700cc to 3100cc.

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Physicochemical Characteristics and Antioxidative Effects of Barley Soybean Paste (Doenjang) Containing Kelp Extracts (다시마 추출물을 첨가한 보리된장의 일반적 특성과 항산화 효과)

  • Oh, Se In;Sung, Jung Min;Lee, Kun Jong
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.43 no.12
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    • pp.1843-1851
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    • 2014
  • This study evaluated the quality characteristics and antioxidant activities of barley Doenjang (soybean paste) containing various contents (4, 12, and 20%) of kelp extracts. After 60 days of fermentation, pH, acidity, and viscosity of Doenjang were 5.80~6.86, 0.57~1.87%, and 4,913.3~9,333.3 cps, respectively, showing significant differences according to content of kelp extracts. Amino-type nitrogen contents was 902.60~921.90 mg%. For color values, L and b values increased significantly (P<0.001), whereas a value decreased slightly according to kelp extracts. DPPH radical scavenging effect ($IC_{50}$) for butylated hydroxyanisole ranged from 10.28 mg/mL to 23.23 mg/mL. DPPH radical scavenging effects of control was highest among the samples. The total polyphenol and flavonoid contents were 12.72~6.37 mg tannic acid equivalence/g, and $0.98{\sim}1.56{\mu}g$ rutin equivalence/g, respectively. Initial counts of total bacteria and lactic acid bacteria were 7.20~7.57 log CFU/g, and 4.20~4.71 log CFU/g respectively, showing significant difference according treatment and fermentation (P<0.05). In the sensory evaluation, 20% kelp extract Doenjang (5.6) showed higher overall acceptability than other samples (6.5) (P<0.01). Especially, umami taste (6.1) and texture (6.4) of 20% kelp extract Doenjang were higher than those of control (P<0.05). These results suggest that Doenjang containing kelp extracts, will be good for industrial fields.

The Effect of Scratch Programming Education for Middle School Students on the Information Science Creative Personality and Technological Problem Solving Tendency (스크래치 프로그래밍 교육이 중학생의 정보과학 창의적 성향과 기술적 문제해결 성향에 미치는 영향)

  • Kim, Ki-Yeol
    • 대한공업교육학회지
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    • v.41 no.2
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    • pp.119-133
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    • 2016
  • This study is aimed at verifying the effect of scratch programming education for middle school students on their information science creative personality and technological problem solving tendency. The results of such study can be used as basic data for raising 'future creative talents' armed with problem-solving capability they honed in software education. The results of this research are as follows. First, a statistically significant difference was confirmed between ex ante and ex post samples in a t-test which was performed to verify information science creative personality of the middle school students (t(37)=4.305, p<.01). Their information science creative personality was high in the average score as it dropped from 3.00 in the ex-ante test to 2.51 in the ex post test. It was confirmed that the education of scratch programming influences information science creative personality for middle school students positively, suggesting that middle school students are interested in new problematic situations they found in information science and discover new problem-solving methods in the programming education, thereby showing positive feedback in the education performance. However, it was revealed that the middle school students were unable to immerse themselves in the scratch programming course completely and change their psychological states. Second, a statistically significant difference was confirmed between ex ante and ex post samples in a t-test which was performed to verify their technological problem solving tendency (t(37)=3.074, p<.01). Their technological problem solving tendency was high in the average score as it dropped from 4.06 in the ex-ante test to 3.55 in the ex post test. It was confirmed that the education of scratch programming influences technological problem solving tendency for middle school students positively: they understood problems associated with technology, explored diverse breakthroughs for the identified problems and assessed and improved resolutions. Third, a moderate correlation was confirmed between their information science creative personality and technological problem solving tendency (r=.343, p<.05). Therefore, it is judged that the middle school students who took scratch programming education demonstrated its influence in the correlation between the imagination for problem solving, positivity in the information science creative personality and the confidence for problem solving in the technological problem solving tendency.

Relationships of Achievement Goal Orientation with Academic Self-efficacy of Specialized High School Students (특성화고등학교 학생의 성취목표지향성과 학업적 자기효능감의 관계)

  • Yang, Jin-Sik;Song, Nak-Hyun;Lee, Chang-Hoon
    • 대한공업교육학회지
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    • v.43 no.2
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    • pp.79-96
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    • 2018
  • In this study, we look at the effect that the achievement goal of specialized high school students has on academic self-efficacy and the difference in academic self-efficacy depending on achievement goal orientation. The purpose of this research is to help students to efficiently increase their academic self-efficacy, develop research and study life guidance measures to improve negative factors, and select professors and learning methods. To achieve the purpose, survey was conducted with achievement goal orientation measurement tools(26 questions) and academic self-efficacy measurement tools(28 questions) for 745 students of 18 specialized technical high school students in 5 districts. The results of this study are as follows. First, preference to task difficulty and self-controlling efficacy have highly positive correlations with mastery goal orientation and confidence and mastery avoidance goal orientation have highly negative correlations each other. Second, achievement goal orientation form of specialized high school students were divided into 5 forms; 'execution avoidance(34.8%)', 'mastery orientation(20.8%)', 'approach(17%)', 'avoidance competition(14.9%)', and'mastery avoidance(12.5%)'. In preference to task difficulty, 'approach'group showed the highest average point and 'mastery avoidance'showed the lowest average point. The average point of 'approach' group was higher than other groups in confidence, but 'mastery orientation' group showed the highest average point. Through the results of this study, academic self-efficacy makes an effect by a certain direction in accordance with achievement goal orientation and it's necessary to access academic problems differently according to student's goal directivity. Therefore, it's necessary to provide educational method by student type based on explanation about academic self-efficacy of achievement goal orientation of specialized high school students and analysis on achievement goal orientation form.