• Korean Journal of Clinical Pharmacy
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• v.31 no.1
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• pp.1-11
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• 2021

Objective: This study aimed to overview and assess the effectiveness of the policies and regulations that have governed new drug access in Korea, and to propose policies to enhance patient access to drugs, particularly for new innovative medicines. Methods: We approached drug access issues in two perspectives: approval lag (or availability) and reimbursement lag (or affordability). The issues were identified and evaluated through the review of literature, public documents, reports published by the government agencies and private organizations, and news articles. Results: To shorten approval lag, it is recommended to hire and train more reviewers at the Ministry of Food and Drug Safety. Increasing user fees to a realistic level can facilitate this process. To reduce reimbursement lag, flexible incremental cost-effectiveness ratio threshold, alternative cost-effectiveness evaluation, and establishment of funding source other than the national health insurance are identified as the areas to be improved. Conclusion: The current policies and regulations had to be supplemented by new systems to drastically promote patient accessibility to new drugs, consequently in order to promote national public health.

• Journal of Korean Association for Spatial Structures
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• v.22 no.4
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• pp.31-38
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• 2022

In this study, an incremental loading test of the HRS(Hybrid Rubber Slit) damper was additionally performed to define the physical characteristics according to the incremental test results, and an analytical study was performed according to the damping design procedure by selecting an example structure. As a result of performing seismic performance evaluation before reinforcement by selecting a RC structure similar to an actual school structure as an example structure, the story drift ratio was satisfied, but some column members collapsed due to bending deformation. In order to secure the seismic performance, the damping design procedure of the HRS damper was presented and performed. As a result of calculating the amount of damping device according to the expected damping ratio and applying it to the example structure, the hysteresis behavior was stable without decrease in strength, and the story drift ratio and the shear force were reduced according to the damping effect. Finally the column members that had collapsed before reinforcement satisfied the LS Level.

• The Journal of Korean Association of Computer Education
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• v.17 no.2
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• pp.97-106
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• 2014

There is a lot of interest in the data storage and backup systems according to increasing the data intensive services and related user's data. The overhead of backup performance in massive storage system is a critical issue because the traditional incremental backup strategies causes the time consuming bottleneck in the SAN environment. The SANique Smart Vault system is a high performance backup solution with data de-duplication technology and it guarantees these requirements. In this paper, we describe the architecture of SANique Smart Vault system and illustrate efficient delta incremental backup method based on journaling files. We also present the record-level data de-duplication method in our proposed backup system. The proposed forever incremental backup and data de-duplication algorithms are analyzed and investigated by performance evaluation of other commercial backup solutions.

• The Journal of the Korea Contents Association
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• v.20 no.6
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• pp.556-578
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• 2020

There are many different researches about how to analyze issues based on real-time news streams. But, there are few researches which analyze issues hierarchically from news articles and even a previous research of hierarchical issue analysis make clustering speed slower as the increment of news articles. In this paper, we propose a hierarchical and incremental clustering for semi real-time issue analysis on news articles. We trained siamese neural network based weighted cosine similarity model, applied this model to k-means algorithm which is used to make word clusters and converted news articles to document vectors by using these word clusters. Finally, we initialized an issue cluster tree from document vectors, updated this tree whenever news articles happen, and analyzed issues in semi real-time. Through the experiment and evaluation, we showed that up to about 0.26 performance has been improved in terms of NMI. Also, in terms of speed of incremental clustering, we also showed about 10 times faster than before.

• Journal of Internet Computing and Services
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• v.4 no.3
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• pp.39-46
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• 2003

Generally, the existing watermarking techniques for copyright protection of a digital image are fragile in geometric distortion and all watermark extractions need the same time regardless of degree of distortion. In this paper, we propose the incremental watermarking technique that used a Complex Wavelet Transform(CWT) in order to solve these problems. The proposed incremental watermarking technique embeds a watermark in a phase component after a CWT with an original image, and a watermark is extracted from an watermarked image by stages. A watermark owner can insist on copyright of an image after comparing a correlation between the extracted watermark and the original watermark if it is larger than the threshold. Also, the incremental watermark extraction determines the extraction time of a watermark by the level of distortion. The proposed technique through performance evaluation displayed that it was robust in geometric distortion than the existing watermarking technique.

• Journal of KIISE:Computer Systems and Theory
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• v.31 no.3_4
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• pp.247-256
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• 2004

This paper presents an efficient collision detection algorithm the performance of which is independent of animation speed. Most of the previous collision detection algorithms are incremental and discrete methods, which find out the neighborhood of the extreme vertex at the previous time instance in order to get an extreme vertex at each time instance. However, if an object collides with another one with a high torque, then the angular speed becomes faster. Hence, the candidate by the incremental algorithms may be farther from the real extreme vertex at this time instance. Therefore, the worst time complexity nay be $O(n^2)$, where n is the number of faces. Moreover, the total time complexity of incremental algorithms is dependent on the time step size of animation because a smaller time step yields more frequent evaluation of Euclidean distance. In this paper, we propose a new method to overcome these drawbacks. We construct a spherical extreme vertex diagram on Gauss Sphere, which has geometric properties, and then generate the distance function of a polyhedron and a plane by using this diagram. In order to efficiently compute the exact collision time, we apply the interval Newton method to the distance function.

• Journal of Korea Multimedia Society
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• v.9 no.11
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• pp.1395-1409
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• 2006

A spatial data warehouse has spatial data cube composed of multi-dimensional data for efficient OLAP(On-Line Analytical Processing) operations. A spatial data cube supporting concept hierarchies holds huge amount of data so that many researches have studied a incremental update method for minimum modification of a spatial data cube. The Cube, however, compressed by eliminating prefix and suffix redundancy has coalescing paths that cause update inconsistencies for some updates can affect the aggregate value of coalesced cell that has no relationship with the update. In this paper, we propose incremental batch update method of a spatial data cube. The proposed method uses duplicated nodes and extended node structure to avoid update inconsistencies. If any collision is detected during update procedure, the shared node is duplicated and the duplicate is updated. As a result, compressed spatial data cube that includes concept hierarchies can be updated incrementally with no inconsistency. In performance evaluation, we show the proposed method is more efficient than other naive update methods.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.25 no.11
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• pp.1685-1696
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• 2001

A novel indentation theory is proposed by examining the data from the incremental plasticity theory based finite element analyses. First the optimal data acquisition location is selected, where the strain gradient is the least and the effect of friction is negligible. This data acquisition point increases the strain range by a factor of five. Numerical regressions of obtained data exhibit that strain hardening exponent and yield strain are the two main parameters which govern the subindenter deformation characteristics. The new indentation theory successfully provides the stress-strain curve with an average error less than 5%.

• Steel and Composite Structures
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• v.20 no.2
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• pp.399-412
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• 2016

This paper evaluates the seismic response of three dimensional steel space buildings using the spread plastic hinge approach. A numerical study was carried out in which a sample steel space building was selected for pushover analysis and incremental nonlinear dynamic time history analysis. For the nonlinear analysis, three earthquake acceleration records were selected to ensure compatibility with the design spectrum defined in the Turkish Earthquake Code. The interstorey drift, capacity curve, maximum responses and dynamic pushover curves of the building were obtained. The analysis results were compared and good correlation was obtained between the idealized dynamic analyses envelopes with and static pushover curves for the selected building. As a result to more accurately account response of steel buildings, dynamic pushover envelopes can be obtained and compared with static pushover curve of the building.

• Computers and Concrete
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• v.20 no.4
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• pp.419-427
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• 2017

A methodology, based on fragility functions, is proposed to evaluate the seismic performance of seismic isolated $45^{\circ}$ skewed concrete bridge: 1) twelve types of seismic isolation devices are considered based on two different design parameters 2) fragility functions of a three-span bridge with and without seismic isolation devices are analytically evaluated based on 3D nonlinear incremental dynamic analyses which seismic input consists of 20 selected ground motions. The optimum combinations of isolation device design parameters are identified comparing, for different limit states, the performance of 1) the Seismic Isolated Bridges (SIB) and 2) Not Seismic Isolated Bridge (NSIB) designed according to the AASHTO standards.