• Journal of Periodontal and Implant Science
• /
• 제38권4호
• /
• pp.579-588
• /
• 2008

Purpose: The purpose of this study was to investigate the association of generalized aggressive periodontitis with IL-6 promoter gene single nucleotide polymorphisms(SNP). Material and Methods: The study population consisted of 52 generalized aggressive periodontitis patients(GAP) and 30 periodontally healthy control subjects, who were systemically healthy non-smokers. Genomic DNA was obtained from buccal swab. The IL-6 promotor SNP at the positions of -597, -572, and -174 were genotyped by amplifying the polymorphic region using polymerase chain reaction(PCR), restriction enzyme digestion and gel electrophoresis. Result: The genotype distributions for G/G, G/A and A/A genotypes of IL-6 -597 were 30.8%, 40.4%, and 28.8% in the GAP group and 53.3%, 40%, and 6.7% in the control group and were statistically different between 2 groups(p<0.05). Allele 2 frequency of IL-6 -597 were significantly higher in the GAP group than the control group(p<0.01). At the position of IL-6 -572, the distribution for C/C, C/G and G/G genotypes were 23.1%, 55.8% and 21.2% in the GAP group and 20%, 33.3%, and 46.7% in the control group. In female subjects, the genotype distribution were significantly different between 2 groups(p<0.01). In male subjects, allele 2 frequency of IL-6-572 was significantly lower in the GAP group than the control group(p<0.05). The genotype distribution of IL-6 -174 in the GAP group were 96.2%, 3.8% for G/G, G/C genotypes whereas only the G/G genotype was detected in the control group. Conclusion: In conclusion, significant associations were found in IL-6 gene promoter(-597, -572) polymorphisms and generalized aggressive periodontitis. Further cohort study will be necessary in larger population.

• 대한치과보철학회지
• /
• 제55권2호
• /
• pp.156-163
• /
• 2017

1급 지적장애는 일상 생활과 사회 생활의 적응이 현저하게 곤란하여 일생 동안 타인의 보호가 필요한 사람으로 보통 불량한 구강환경을 가지며 치아 우식, 치근단 염증 및 다수의 치아 결손을 보여 적절한 보철적 회복을 필요로 한다. 다수의 치아가 결손된 지적장애 환자의 경우 가철성 보철물의 안정, 유지와 관리가 어렵기 때문에 고정성 보철이 필요하며 임플란트 치료가 유일한 방법이다. 본 증례는 1급 지적장애인 45세 남성환자로 불량한 구강환경으로 인해 대부분의 치아가 상실되어 저작기능 회복을 위해 내원하였으며 임플란트 및 생체친화적이고 강한 강도의 단일 구조 지르코니아를 이용한 고정성 보철물로 최종 수복하였다. 이상의 치료과정 결과 심미적, 기능적으로 만족할 만한 결과를 얻을 수 있었기에 보고하는 바이다.

• Journal of Periodontal and Implant Science
• /
• 제47권5호
• /
• pp.328-338
• /
• 2017

Purpose: Chronic periodontitis is an inflammatory disease induced by pathogenic bacterial accumulation. A novel index, the periodontal inflamed surface area (PISA), represents the sum of the periodontal pocket depth of bleeding on probing (BOP)-positive sites. It is advantageous for data processing and analysis because it can be treated as a continuous variable to quantify periodontal inflammation. In the present study, we evaluated correlations between PISA and periodontal classifications, and examined PISA as an index integrating the discrete conventional periodontal indexes. Methods: This study was a cross-sectional subgroup analysis of data from a prospective cohort study investigating the association between chronic periodontitis and the clinical features of ankylosing spondylitis. Data from 84 patients without systemic diseases (the control group in the previous study) were analyzed in the present study. Results: PISA values were positively correlated with conventional periodontal classifications (Spearman correlation coefficient=0.52; P<0.01) and with periodontal indexes, such as BOP and the plaque index (PI) (r=0.94; P<0.01 and r=0.60; P<0.01, respectively; Pearson correlation test). Porphyromonas gingivalis expression and the presence of serum P. gingivalis antibodies were significant factors affecting PISA values in a simple linear regression analysis, together with periodontal classification, PI, bleeding index, and smoking, but not in the multivariate analysis. In the multivariate linear regression analysis, PISA values were positively correlated with the quantity of current smoking, PI, and severity of periodontal disease. Conclusions: PISA integrates multiple periodontal indexes, such as probing pocket depth, BOP, and PI into a numerical variable. PISA is advantageous for quantifying periodontal inflammation and plaque accumulation.

• Clinics in Shoulder and Elbow
• /
• 제13권1호
• /
• pp.92-98
• /
• 2010

목적: 견봉 쇄골 관절 손상의 치료 방법으로서 Clavicle hook plate를 이용한 고정술의 결과를 분석하였다. 대상 및 방법: 2008년 2월부터 2010년 4월까지 본원에서 견봉 쇄골 관절 탈구로 Clavicle hook plate를 이용한 고정술을 시행하였던 18예를 대상으로 하였다. 제 3형의 견봉 쇄골 관절 손상이 7예, 제 5형이 11예였으며, Clavicle hook plate는 수술 후 3개월 이후에 제거하였다. 치료 결과의 판정은 스트레스 부하 방사선 촬영을 하여 건측과 비교하였고 Korean shoulder scoring system 및 American shoulder elbow society score를 이용하여 견관절의 기능과 환자의 만족도를 평가하였다. 평균 추시 기간은 9개월이었다. 결과: 스트레스 부하 방사선 사진에서 오구 쇄골 간격이 건측에 비해 수술 전 평균 114% 증가되어 있었으나 수술 후 최종 추시 시 23%로 감소하였으며, Korean shoulder scoring system은 평균 80점이었고 American shoulder elbow society score는 평균 74점이었다. 결론: 견봉 쇄골 관절 손상의 Clavicle hook plate를 이용한 고정 시 충분한 관절 안정성으로 조기 재활이 가능하며, 방사선학적 및 기능적으로도 비교적 만족할만한 결과를 얻을 수 있어 수술적 치료에 있어 유용한 방법 중 하나라고 사료된다.

• Journal of Periodontal and Implant Science
• /
• 제44권1호
• /
• pp.13-19
• /
• 2014

Purpose: The purpose of this study was to retrospectively evaluate the survival of periodontally hopeless teeth that were intentionally extracted and replanted after a delay and to compare the radiographic characteristics of the survival group with those of the failure group. Methods: The clinical and radiographic data from patients who underwent delayed intentional replantation between March 2000 and July 2010 were reviewed. Twenty-seven periodontally hopeless teeth were extracted and preserved in medium supplemented with antibiotics for 10-14 days. The teeth were then repositioned in the partially healed extraction socket and followed for 3 to 21 months. The radiographic parameters were analyzed using a paired t test and the cumulative survival rate was analyzed using Kaplan-Meier analysis. Results: Seven replanted teeth failed and the overall cumulative survival rate was 66.4%. In the survival group, the amount of bone loss was reduced from 68.45% to 34.66% three months after replantation. There was radiologic and clinical evidence of ankylosis with 5 teeth. However, no root resorption was found throughout the follow-up period. In the failure group, bone formation occurred from the bottom of the socket. However, a remarkable radiolucent line along the root of a replanted tooth existed. The line lengthened and thickened as time passed. Finally, in each case of failure, the tooth was extracted due to signs of inflammation and increased mobility. Conclusions: Delayed intentional replantation has many advantages compared to immediate intentional replantation and could serve as an alternative treatment for periodontally involved hopeless teeth. However, techniques for maintaining the vitality of periodontal structures on the tooth surface should be developed for improved and predictable results.

• Journal of Periodontal and Implant Science
• /
• 제31권1호
• /
• pp.257-269
• /
• 2001

Removal of subgingival calculus is essential for the success in periodontal treatment. Subgingival instrumentation is used for the removal of all bacterial plaque and calculus. In this study, Gracey curet and Ultrasonic curet were used on single rooted teeth to conduct subgingval scaling and root planning. The remaining amount of calculus was evaluated according to type of instrument, depth of pocket, and tooth surface. 24 teeth were extracted from 14 patients being treated at department Periodontology Seoul Advantist dental hospital were used. Total 96 area(4 surface per teeth) were evaluated. 12 teeth treated with Gracey curet were used as the control group and the other 12 teeth treated with Ultrasonic curet were examined for experimental group. The 4 surface of the teeth(buccal, mesial, lingual or palatal, distal) were observed through the stereomicroscope and the images of the surface were captured and saved in CCD. The images were displayed on the monitor and the amount of calculus remained was evaluated by overlapping $10{\times}10$ grid pixel screen produced by Microsoft power point. The results evaluated were as follows 1. There was no statistically significant difference in residual calculus and tooth position following scaling and root planning of all group, but statistically significant correlation with residual calculus, probing depth, instruments and tooth surface. 2. There was statistically significant correlation between residual calculus and probing depth, but no statistically significant difference in residual calculus, tooth surface and tooth position on experimental(Ultrasonic curet) group. 3. There was no statistically significant difference in residual calculus according to the pre-treatment pocket depth and tooth position, but statistically significant correlation with tooth surface. The amount of residual calculus increase with mesial, distal, buccal and lingual(or palatal) surface on control(Gracey curet) group. 4. The Gracey showed better results than ultrasonic curet in mesial and distal surface, and there is significant difference. The results demonstrate that ultrasonic curet alone is inadequate for thorough subgingival debridement and suggest that Ultrasonic curet with Gracey curet should be more effective.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• 제34권5호
• /
• pp.326-331
• /
• 2012

Purpose: Length measurement from maxillary anterior teeth root tip to nasal floor is incorrect in panoramic radiography. Comparison of cone beam computed tomography (CBCT) and panoramic radiography should be helpful in determining the vertical length. Methods: Sixty nine patients were taken CBCT and panoramic radiography of the maxillary anterior. First measurement is length of parallel lines from the central incisor and lateral incisor root tip to nasal floor on CBCT. Second measurement is length of perpendicular lines from the central incisor and lateral incisor root tip to nasal floor on CBCT. Third measurement is length from the central incisor and lateral incisor root tip to nasal floor on panoramic radiographys. Results: In the first measurement of the maxillary central incisors, an average of $11.36{\pm}2.49$ mm in males and $10.49{\pm}2.17$ mm in females. In the second measurement of the maxillary central incisors, $10.41{\pm}2.42$ mm in males and $9.18{\pm}2.08$ mm in females. In the third measurement of the maxillary central incisors, $10.71{\pm}2.20$ mm in males and $9.27{\pm}2.10$ mm in females. In the first measurement of the maxillary lateral incisors, an average of $13.40{\pm}2.04$ mm in males and $11.96{\pm}2.20$ mm in females. In the second measurement of the maxillary lateral incisors, $11.25{\pm}1.82$ mm in males and $10.06{\pm}1.68$ mm in females. In the third measurement of the maxillary lateral incisors, $11.47{\pm}2.01$ mm in males and $10.13{\pm}1.70$ mm in females. Conclusion: The vertical length from root tip to nasal floor was longer in male than female (P>0.05). First measurement was longer than third measurement (P<0.05). This is the actual placement of the implant site measured on the vertical length than the length of the panorama means that there are a few more free. The first measurement was longer than 114% over the third measurement.

• 대한심미치과학회지
• /
• 제22권1호
• /
• pp.47-55
• /
• 2013

치아의 상실로 인한 국소적 치조제 결손(localized alveolar defect)은 고정성 국소의치(fixed partial denture) 제작시에 많은 기능적, 심미적 문제점들을 야기한다. 특히 전치부에서의 치조제 결손 부위는 그 형태와 양상에 따라서 심미적 결과에 많은 영향을 미치게 되는데, 이 결손 부위의 회복 여부가 최종적인 심미적 결과의 성패를 좌우하게 된다. 치조제 결손의 양상은 발치 전 치조골의 상황과 염증 정도에 따라 다양하게 나타날 수 있는데, 그 양상은 크게 보면 수평적, 수직적, 혹은 복합적 결손 등으로 분류할 수 있다. 이러한 결손부의 형태와 양에 따라서 우리가 회복시켜 주어야 할 정도도 다르고, 그 난이도 또한 다르다고 할 수 있다. 여기에 추가적으로 고려되어야 할 요소가 결손부와 자연치가 만나는 proximal gingival height이다. 인접 치아와 접하는 gingival height는 그 부위의 치조골 높이에 많은 영향을 받게 되는데, 만약 이 부위에 결손이 존재한다면 역시 심미적 결과에 부정적인 영향을 줄 것이다. 하지만 결손부위 내에서도 치아와 인접한 부위의 gingival height를 동시에 증대시키기 위해 소개된 technique은 많지 않으며 시술의 예지성도 높지 않은 것이 사실이다. 이 case report에서 필자는 수평적 혹은 수직적 결손 및 복합적 결손에 다양하게 적용 가능하면서도 인접치아와 인접한 부위의 gingival height에도 도움이 될 수 있는 술식을 소개하려고 한다.

• 대한심미치과학회지
• /
• 제22권1호
• /
• pp.30-46
• /
• 2013

치과에서 수복물제작에는 지난 50년간 금속을 이용한 금속도재관이 많이 사용되어 왔다. 그러다 보니 심미적이고 생체 친화적이며 금속 알러지등의 문제로 인한 환자들의 사고의 변화에 따라서 'metal free restoration'에 대한 관심이 점점 높아지고 있다. 특히 그 동안 많이 사용되어왔던 귀금속 가격이 급등하여 더 이상 구강 내 수복 물로써 제 역할을 하는 것은 불가능하게 되었으며, PFM수복은 술자로 하여금 chipping과 파절로 인한 문제점을 안고 있다. 따라서 구치부 임플란트 수복물로써 보다 심미적이고 강도가 높은 재료의 요구로 인하여 그 어느 때보다 CAD/CAM이 주목을 받고 있다. Full zirconia 수복을 위해서 고려해야 할 사항은 1. 강도 2. 콤비네이션 작업은? 3. 빛 투과성은? 4. crack이 발생한 경우의 처치는? 5. 블럭의 색조 재현상은? 6. 대합치 마모도 7. 저온 열화 현상 등을 들 수가 있는데, 본 연구에서는 블럭의 색조 재현상에 대해서 정리하고자 한다. Full zirconia 수복을 꺼려하는 가장 커다란 이유 중에 하나가 바로 기존의 PFM 수복과 비교했을 때 자연스러운 색조를 재현하기가 어렵다는 점이며, 교합 조정 후에 컬러링한 표면이 삭제된 후 나타나는 보기 싫은 블럭의 노출로 인하여 많은 임상가들이 꺼려하고 있다. 지르코잔의 블럭을 약 4년 여 동안 사용하면서 이러한 점들은 어느 정도 극복되어질 수 있는 문제라고 여겨지며, 어떻게 하면 그 가급적 주변 보철물 또는 자연 치아와의 조화 이룰 수 있는 수복물을 만들 수 있을 것인가에 관해 정리였다.

• Journal of Periodontal and Implant Science
• /
• 제24권3호
• /
• pp.618-632
• /
• 1994

The ultimate goal of periodontal therapy is promoting the regeneration of lost periodontal tissue. The purpose of this study is to evaluate the effect of treatment using decalcified freeze dried bone allograft as a bone graft material. 47 intrabony defects from 27 patients with clinical diagnosis of chronic periodontitis were selected among those 24 defects were treated via flap operation only and designated as the control group, the other 23 defects were treated with decalcified freeze dired bone allografting via flap operation and designated as the experimental group. Clinical parameters including probing depth, loss of attachment, probing bone level and gingival recession have been recorded at 6th months, and the significance of the changes has been analyzed. The results are as follows : 1. Probing depths were reduced significantly in both control group($2.75{\pm}0.99mm$) and experimental group($3.69{\pm}0.97mm$) postoperatively(p<0.01). Experimental group showed significantly higher decrease compared to the control group(p]0.01). 2. Loss of attachment showed statistically significant decrease in both control group($1.77{\pm}1.08mm$) and experimental group postoperatively($2.70{\pm}1.55mm$). Experimental group showed significantly higher decrease compared to the control group(p]0.05). 3. Probing bone levels were reduced with statistically significance in both control group($1.08{\pm}0.97mm$) and experimental group($4.00{\pm}1.41mm$) postoperatively(p<0.01). Experimental group showed significantly higher decrease compared to the control group(p<0.01). 4. Gingival recession showed statistically significant increase in the control group($1.21{\pm}0.72mm$) and experimental group($1.00{\pm}1.09mm$) postoperatively(p<0.01). There was no statistical significance between the control group and the experimental group. On the basis of these results, treatment using allogenic decalcified freeze dried bone is effective in reducing probing depth, loss of attachment and probing bone level. Therefore allogenic decalcified freeze dried bone is an effective bone graft material in periodontal regeneration.