• Journal of Microbiology and Biotechnology
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• v.18 no.1
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• pp.145-152
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• 2008

A cell-based in vitro exposure system was developed to determine whether oxidative stress plays a role in the cytotoxic effects of volatile organic compounds (VOCs) such as benzene, toluene, xylene, and chlorobenzene, using human epithelial HeLa cells. Thin films based on cysteine-terminated synthetic oligopeptides were fabricated for immobilization of the HeLa cells on a gold (Au) substrate. In addition, an immobilized cell-based sensor was applied to the electrochemical detection of the VOCs. Layer formation and immobilization of the cells were investigated with surface plasmon resonance (SPR), cyclic voltammetry (CV), and electrochemical impedance spectroscopy (EIS). The adhered living cells were exposed to VOCs; this caused a change in the SPR angle and the VOC-specific electrochemical signal. In addition, VOC toxicity was found to correlate with the degree of nitric oxide (NO) generation and EIS. The primary reason for the marked increase in impedance was the change of aqueous electrolyte composition as a result of cell responses. The p53 and NF-${\kappa}B $ downregulation were closely related to the magnitude of growth inhibition associated with increasing concentrations of each VOC. Therefore, the proposed cell immobilization method, using a self-assembly technique and VOC-specific electrochemical signals, can be applied to construct a cell microarray for onsite VOC monitoring.

• International Journal of Heart Failure
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• v.6 no.1
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• pp.22-27
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• 2024

Body fluid monitoring and management are essential to control dyspnea and prevent re-hospitalization in patients with chronic heart failure (HF). There are several methods to estimate and monitor patient's volume status, such as symptoms, signs, body weight, and implantable devices. However, these methods might be difficult to use for reasons that are slow to reflect body water change, inaccurate in specific patients' condition, or invasive. Bioelectrical impedance analysis (BIA) is a novel method for body water monitoring in patients with HF, and the value in prognosis has been proven in previous studies. We aim to determine the efficacy and safety of home BIA body water monitoring-guided HF treatment in patients with chronic HF. This multi-center, open-label, randomized control trial will enroll patients with HF who are taking loop diuretics. The home BIA group patients will be monitored for body water using a home BIA device and receive messages regarding their edema status and direction of additional diuretics usage or behavioral changes through the linked application system once weekly. The control group patients will receive the usual HF management. The primary endpoint is the change in N-terminal prohormone of brain natriuretic peptide levels from baseline after 12 weeks. This trial will provide crucial evidence for patient management with a novel home BIA body water monitoring system in patients with HF.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.46 no.5
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• pp.38-43
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• 2009

We derive an equation that predicts the induced voltage across the receiving terminals of the three-coil head of a metal detector using a magnetic vector potential approach. We also derive an equation that relates the change of the impedance of the transmitting coil to the properties of the metal. We utilize the results to obtain the optimum spacing between the driving and the receiving coils at which the maximum induced voltage is attained. Further, we determine the position of the metallic object where the voltage reaches its peak. We verify our work by comparing the results with those of a previous work.

• 한국신재생에너지학회:학술대회논문집
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• 2011.11a
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• pp.85.1-85.1
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• 2011

In this study, Grafoil$^{TM}$ which has comparable electric resistance and chemical stability but is flexible, fragile, and cheap material was adopted as bipolar plates for proton exchange membrane fuel cell(PEMFC) having only one straight line flow channel. Because of its flexibility, pressurizations of cell with various pressures showed different operating characteristics compared to ordinary graphite-used PEMFC. While performances of both cells decreased as these were pressurized, investigation of ohmic and faradaic resistance by electrochemical impedance measurement indicated different tendency of change. Ohmic resistance of graphite-used cell increased with increasing pressure, which is reversed in Grafoil$^{TM}$-used cell. It is speculated that effective chemical reaction area is decreased with increasing pressure in case of graphite-used one, but because of flexible property of Grafoil$^{TM}$, gas diffusion layer in Grafoil$^{TM}$-used cell was well-activated. Different rate of change of faradaic resistances in both cells support this supposition. However, although optimum point of pressurization is found, it is required to investigate other operating conditions because of low performance compared to graphite-used cell.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2001.05a
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• pp.18-22
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• 2001

Spinel $LiMn_{2-y}Mn_{y}O_4$ powder was prepared solid-state method by calcining the mixture of $LiOH{\cdot}H_2O$, $MnO_2$ and MgO at $800^{\circ}C$ for 36h. To investigate the effect of temperature for cycle behaviour of cathode material during cycling, charge-discharge experiments and initial impedance spectroscopy performed by the condition of the charge-discharge temperature. Initial charge-discharge capacity was gradually increased by rising charge-discharge temperature. However, capacity was suddenly decreased at high temperature during cycling. Capacity at low temperature was almost constant during cycling. It confirmed because Mn dissolution is more serious at high temperature than at low temperature.

• Journal of Sensor Science and Technology
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• v.4 no.4
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• pp.41-46
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• 1995

Sensor system which can detect a flowing cell is designed and fabricated by semiconductor processing and EDM(Electro-chemical Discharge drilling Method). Two methods are used in this paper; 1) optical method which measures the trasmitted light through the cell passage between transmitter and receiver, 2) impedance method which measures impedance change between electrodes, when cell flows in the cell passage. Experimental result using tabaco leaves shows that the ouput value by optical method is 0.2V to 0.7V, and the output by impedance method is 0.2V to 2V, which is bigger, but it includes an avoidable noises.

• Agricultural and Biosystems Engineering
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• v.2 no.2
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• pp.63-68
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• 2001

The objective of this study was to develop a real-time soil moisture meter using RF impedance. The impedance suchas capacitance and resistance (or conductance) was analyzed using parallel cylinder type capacitance probe(C-probe) and Q-meter (HP4342). The capacitance and conductance of soil increased as volumetric water content increased. The 5 MHz of modified Colpitts type crystal oscillator was designed to detect the capacitance change of the C-probe with moist soil. A third order polynomial regression model was proposed to describe the relationship between RF impedance and volumetric water content. The prototype real time moisture meter consisted of the C-probe, sample container, oscillator, frequency counter and related signal processing units. The calibration equation for measurement of volumetric moisture content of soil was developed and validated. The correlation coefficient and root mean square error between measured volumetric water content by oven method and predicted values by prototype moisture meter for unknown soil samples were 0.984 and 0.032$cm^3$$cm\^3$, respectively.

• Journal of the Korea Institute of Military Science and Technology
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• v.4 no.2
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• pp.122-129
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• 2001

A characterization procedure for analyzing symmetric coupled MIS(Metal-Insulator-Semiconductor) transmission line is used the same procedure as a general single layer symmetric coupled line with perfect dielectric substrate from the extraction of the characteristic impedance and propagation constant for even- and odd-mode. In this paper, an analysis for a new substrate shielding symmetric coupled MIS structure consisting of grounded crossbar at the interface between Si and SiO2 layer using the Finite- Difference Time-Domain(FDTD) method is presented. In order to reduce the substrate effects on the transmission line characteristics, a shielding structure consisting of grounded crossbar lines over time-domain signal has been examined. Symmetric coupled MIS transmission line parameters for even- and odd-mode are investigated as the functions of frequency, and the extracted distributed frequency- dependent transmission line parameters and corresponding equivalent circuit parameters as well as quality factor for the new MIS crossbar embedded structure are also presented. It is shown that the quality factor of the symmetric coupled transmission line can be improved without significant change in the characteristic impedance and effective dielectric constant.

• Membrane Journal
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• v.27 no.5
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• pp.434-440
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• 2017

Electrical impedance spectroscopy is used to detect membrane fouling in-situ in reverse electrodialysis. The impedance data for the AMX membrane being fouled in the reverse electrodialysis are plotted and analyzed by Nyquist and admittance method. The meaningful graphical analyses for the fouling phenomena could be done by both Nyquist and admittance method. In addition, the unstable initial fouling stage was identified by the admittance data with high standard deviation, and the structural change of the fouling layer formed at the surface of anion-exchange membranes with the operation time of reverse electrodialysis was also detected.

• Journal of the Korean Society for Precision Engineering
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• v.34 no.2
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• pp.115-123
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• 2017

This paper presents the design and the control performance of a novel dynamic compliant-arm support with parallel elastic actuators that was developed to assist with the daily living activities of those whose arms are compromised by muscular disease or the aging process. The parallel elastic-arm support consists of a compliant mechanism with combined passive and active components for human interaction and to reach the user's desired positions. The achievement of these tasks requires impedance control, which can change the virtual stiffness, damping coefficients, and equilibrium points of the system; however, the desired-position tracking by the impedance control is limited when the end-effector weight varies according to the equipping of diverse objects. A prompt algorithm regarding weight calibration and friction compensation is adopted to overcome this problem. A result comparison shows that, by accurately assessing the desired workspace, the proposed algorithm is more effective for the accomplishment of the desired activities.