• Progress in Medical Physics
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• v.29 no.4
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• pp.150-156
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• 2018

This study aims to develop an improved Feldkamp-Davis-Kress (FDK) reconstruction algorithm using anisotropic total variation (ATV) minimization to enhance the image quality of low-dose cone-beam computed tomography (CBCT). The algorithm first applies a filter that integrates the Shepp-Logan filter into a cosine window function on all projections for impulse noise removal. A total variation objective function with anisotropic penalty is then minimized to enhance the difference between the real structure and noise using the steepest gradient descent optimization with adaptive step sizes. The preserving parameter to adjust the separation between the noise-free and noisy areas is determined by calculating the cumulative distribution function of the gradient magnitude of the filtered image obtained by the application of the filtering operation on each projection. With these minimized ATV projections, voxel-driven backprojection is finally performed to generate the reconstructed images. The performance of the proposed algorithm was evaluated with the catphan503 phantom dataset acquired with the use of a low-dose protocol. Qualitative and quantitative analyses showed that the proposed ATV minimization provides enhanced CBCT reconstruction images compared with those generated by the conventional FDK algorithm, with a higher contrast-to-noise ratio (CNR), lower root-mean-square-error, and higher correlation. The proposed algorithm not only leads to a potential imaging dose reduction in repeated CBCT scans via lower mA levels, but also elicits high CNR values by removing noisy corrupted areas and by avoiding the heavy penalization of striking features.

• Progress in Medical Physics
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• v.32 no.3
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• pp.59-69
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• 2021

Purpose: The relationship between computed tomography (CT) number and electron density (ED) has been investigated in previous studies. However, the role of these measures for guiding cancer treatment remains unclear. Methods: The CT number was plotted against ED for different imaging protocols. The CT number was imported into ED tables for the Pinnacle treatment planning system (TPS) and was used to determine the effect on dose calculations. Conversion tables for radiation dose calculations were generated and subsequently monitored using a dosimeter to determine the effect of different CT scanning protocols and treatment sites. These tables were used to retrospectively recalculate the radiation therapy plans for 41 patients after an incorrect scanning protocol was inadvertently used. The gamma index was further used to assess the dose distribution, percentage dose difference (DD), and distance-to-agreement (DTA). Results: For densities <1.1 g/cm³, the standard deviation of the CT number was ±0.6% and the greatest variation was noted for brain protocol conditions. For densities >1.1 g/cm³, the standard deviation of the CT number was ±21.2% and the greatest variation occurred for the tube voltage and head and neck (H&N) protocol conditions. These findings suggest that the factors most affecting the CT number are the tube voltage and treatment site (brain and H&N). Gamma index analyses for the 41 retrospective clinical cases, as well as brain metastases and H&N tumors, showed gamma passing rates >90% and <90% for the passing criterion of 2%/2 and 1%/1 mm, respectively. Conclusions: The CT protocol should be carefully decided for TPS. The correct protocol should be used for the corresponding TPS based on the treatment site because this especially affects the dose distribution for brain metastases and H&N tumor recognition. Such steps could help reduce systematic errors.

• The Bulletin of The Korean Astronomical Society
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• v.46 no.2
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• pp.45.1-45.1
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• 2021

Horizon Run 5 (HR5) is a cosmological hydrodynamical simulation which captures the properties of the Universe on aGpc scale while achieving a resolution of 1kpc. This enormous dynamic range allows us to simultaneously capture the physics of the cosmic web on very large scales and account for the formation and evolution of dwarf galaxies on much smaller scales. On the back of a remarkable achievement of this, we have finished to run follow-up simulations which have 2 times larger volume than before and are expected to complementary to some limitations of previous HR simulations both for the study on the large scale features and the expansion history in a distant Universe. For these simulations, we consider the sub-grid physics of radiative heating/cooling, reionization, star formation, SN/AGN feedbacks, chemical evolution and the growth of super-massive blackholes. In order to do this project, we implemented a hybrid MPI-OpenMP version of the RAMSES code, 'RAMSES-OMP', which is specifically designed for modern many-core many thread parallel systems. These simulation successfully reproduce various observation result and provide a large amount of statistical samples of Lyman-alpha emitters and protoclusters which are important to understand the formation and expansion history of early universe. These are invaluable assets for the interpretation of current ΛCDM cosmology and current/upcoming deep surveys of the Universe, such as the world largest narrow band imaging survey, ODIN (One-hundred-square-degree Dark energy camera Imaging in Narrow band).

• The Korea Journal of Herbology
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• v.22 no.4
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• pp.95-100
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• 2007

Objectives : The purpose of this study is to investigate the delayed luminescence-biophoton emission from roots of Angelica gigas N., Angelica sinensis D., and Angelica acutiloba K These three species of Genus Angelica are now used as 'Danggui' in Traditional Korean Medicine. Methods : Randomly selected samples from roots of Angelica gigas N., Angelica sinensis D., and Angelica acutiloba K were radiated with 150 W metal halide lamp for 1 minute. After radiation, biophoton emissions of each sample were detected by electron multiplication-charge coupled device camera. The detected biophoton image was calculated with unit of counts per pixel. Results : The average and maximum biophoton emissions of delayed luminescence with electron multiplication ratio of ${\times}150$ and ${\times}250$were distinguished significantly between Angelica gigas N. and the other two species. Conclusions : These results suggest that biophoton imaging of roots of Angelica gigas N., Angelica sinensis D., and Angelica acutiloba K. could become the meaningful method for the study of differentiation between root of Angelica gigas N. and the other two species, Angelica sinensis D. and Angelica acutiloba K.

• Korean Journal of Optics and Photonics
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• v.20 no.1
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• pp.23-28
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• 2009

In this study, we propose an image stitching method for large-area holographic photo lithography. In this method, a hologram medium become a hologram mask for lithography. And the mask has information for stitched images. These images are recorded by signal images which are controlled with DMD (digital micro-mirror device), and serial hologram recording is achieved with a motorized linear stage. Using this method, fringe seams appear on the stitching area. To remove these fringe seams, double exposure holographic lithography is tried. Each stitched image is recorded and reconstructed with a different reference beam. The experiments confirm that fringe seams are removed.

• Journal of The Korean Astronomical Society
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• v.48 no.5
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• pp.237-255
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• 2015

The Interferometric Monitoring of Gamma–ray Bright Active galactic nuclei (iMOGABA) program provides not only simultaneous multifrequency observations of bright gamma–ray detected active galactic nuclei (AGN), but also covers the highest Very Large Baseline Interferometry (VLBI) frequencies ever being systematically monitored, up to 129 GHz. However, observation and imaging of weak sources at the highest observed frequencies is very challenging. In the second paper in this series, we evaluate the viability of the frequency phase transfer technique to iMOGABA in order to obtain larger coherence time at the higher frequencies of this program (86 and 129 GHz) and image additional sources that were not detected using standard techniques. We find that this method is applicable to the iMOGABA program even under non–optimal weather conditions.

• Korean Journal of Optics and Photonics
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• v.18 no.2
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• pp.122-129
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• 2007

Generally, many kinds of phase unwrapping algorithm are used to obtain three-dimensional features in digital holography. The Goldstein algorithm is ra epresentative method. which requires small memory capacity and short execution time fer an unwrapping process. However, the Goldstein algorithm has some problems when the dipole residue is located at the boundary. When the opposite residues are located at the boundary and the distance between the opposite residues is longer than the boundary, an incorrect branch cut occurs and results in incorrect calculation. We have modified the Goldstein algorithm to solve the incorrect calculation problem using boundary information. We found that the modified Goldstein algorithm could resolve the Goldstein algorithm's problem.

• Publications of The Korean Astronomical Society
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• v.30 no.2
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• pp.409-411
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• 2015

Galaxy clusters, the largest gravitationally bound systems, are an important subject of study to place constraints on cosmological models. Moreover, they are excellent places to test galaxy evolution models in connection to their environments. To date, massive clusters have been found unexpectedly (Kang & Im 2009; Gonzales et al. 2012) and the evolution of galaxies in clusters is still controversial (Elbaz et al. 2007; Faloon et al. 2013). Finding galaxy cluster candidates at z > 1 in a wide, deep imaging survey data will enable us to solve such issues of modern extragalactic astronomy. We report new candidate galaxy clusters in one of the wide and deep survey fields, the European Large Area ISO Survey North1 (ELAIS-N1) and North2 (ELAIS-N2) fields, covering a sky area of $8.75deg^2$ and $4.85deg^2$ each. We also suggest a new useful color selection technique to separate z > 1 galaxies from low - z galaxies by combining multi-wavelength data.

• Nuclear Engineering and Technology
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• v.54 no.12
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• pp.4671-4678
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• 2022

The purpose of this comprehensive research is to observe the impact of scintillator crystal type on entire detection process. For this aim, MCNPX (version 2.6.0) is used for designing of a physical plastic scintillation detector available in our laboratory. The modelled detector structure is validated using previous studies in the literature. Next, different types of plastic scintillation crystals were assessed in the same geometry. Several fundamental detector properties are determined for six different plastic scintillation crystals. Additionally, the deposited energy quantities were computed using the MCNPX code. Although six scintillation crystals have comparable compositions, the findings clearly indicate that the crystal composed of PVT 80% + PPO 20% has superior counting and detecting characteristics when compared to the other crystals investigated. Moreover, it is observed that the highest deposited energy amount, which is a result of the highest collision number in the crystal volume, corresponds to a PVT 80% + PPO 20% crystal. Despite the fact that plastic detector crystals have similar chemical structures, this study found that performing advanced Monte Carlo simulations on the detection discrepancies within the structures can aid in the development of the most effective spectroscopy procedures by ensuring maximum efficiency prior to and during use.

• Progress in Medical Physics
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• v.25 no.2
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• pp.72-78
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• 2014

The aim of the study is to test a hypothesis that quasi-breath-hold (QBH) biofeedback improves the residual respiratory motion management in gated 3D thoracic MR imaging, reducing respiratory motion artifacts with insignificant acquisition time alteration. To test the hypothesis five healthy human subjects underwent two gated MR imaging studies based on a T2 weighted SPACE MR pulse sequence using a respiratory navigator of a 3T Siemens MRI: one under free breathing and the other under QBH biofeedback breathing. The QBH biofeedback system utilized the external marker position on the abdomen obtained with an RPM system (Real-time Position Management, Varian) to audio-visually guide a human subject for 2s breath-hold at 90% exhalation position in each respiratory cycle. The improvement in the upper liver breath-hold motion reproducibility within the gating window using the QBH biofeedback system has been assessed for a group of volunteers. We assessed the residual respiratory motion management within the gating window and respiratory motion artifacts in 3D thoracic MRI both with/without QBH biofeedback. In addition, the RMSE (root mean square error) of abdominal displacement has been investigated. The QBH biofeedback reduced the residual upper liver motion within the gating window during MR acquisitions (~6 minutes) compared to that for free breathing, resulting in the reduction of respiratory motion artifacts in lung and liver of gated 3D thoracic MR images. The abdominal motion reduction in the gated window was consistent with the residual motion reduction of the diaphragm with QBH biofeedback. Consequently, average RMSE (root mean square error) of abdominal displacement obtained from the RPM has been also reduced from 2.0 mm of free breathing to 0.7 mm of QBH biofeedback breathing over the entire cycle (67% reduction, p-value=0.02) and from 1.7 mm of free breathing to 0.7 mm of QBH biofeedback breathing in the gated window (58% reduction, p-value=0.14). The average baseline drift obtained using a linear fit was reduced from 5.5 mm/min with free breathing to 0.6 mm/min (89% reduction, p-value=0.017) with QBH biofeedback. The study demonstrated that the QBH biofeedback improved the upper liver breath-hold motion reproducibility during the gated 3D thoracic MR imaging. This system can provide clinically applicable motion management of the internal anatomy for gated medical imaging as well as gated radiotherapy.