• Proceedings of the Korean Society of Medical Physics Conference
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• 2003.09a
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• pp.3-11
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• 2003

• Proceedings of the Korean Society of Medical Physics Conference
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• 1999.11a
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• pp.238-239
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• 1999

• Proceedings of the Korean Society of Medical Physics Conference
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• 1999.11a
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• pp.266-267
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• 1999

• Progress in Superconductivity and Cryogenics
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• v.18 no.2
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• pp.1-4
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• 2016

To observe the superconducting current and structural properties of high critical temperature ($T_c$) superconductors (HTS), we suggest the following imaging methods: Room temperature imaging (RTI) through thermal heating, low-temperature bolometric microscopy (LTBM) and Raman scattering imaging. RTI and LTBM images visualize thermal-electric voltages as different thermal gradients at room temperature (RT) and superconducting current dissipation at near-$T_c$, respectively. Using RTI, we can obtain structural information about the surface uniformity and positions of impurities. LTBM images show the flux flow in two dimensions as a function of the local critical currents. Raman imaging is transformed from Raman survey spectra in particular areas, and the Raman vibration modes can be combined. Raman imaging can quantify the vibration modes of the areas. Therefore, we demonstrate the spatial transport properties of superconducting materials by combining the results. In addition, this enables visualization of the effect of current flow on the distribution of impurities in a uniform superconducting crystalline material. These imaging methods facilitate direct examination of the local properties of superconducting materials and wires.

• Molecules and Cells
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• v.39 no.12
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• pp.841-846
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• 2016

Local protein synthesis mediates precise spatio-temporal regulation of gene expression for neuronal functions such as long-term plasticity, axon guidance and regeneration. To reveal the underlying mechanisms of local translation, it is crucial to understand mRNA transport, localization and translation in live neurons. Among various techniques for mRNA analysis, fluorescence microscopy has been widely used as the most direct method to study localization of mRNA. Live-cell imaging of single RNA molecules is particularly advantageous to dissect the highly heterogeneous and dynamic nature of messenger ribonucleoprotein (mRNP) complexes in neurons. Here, we review recent advances in the study of mRNA localization and translation in live neurons using novel techniques for single-RNA imaging.

• Journal of the Optical Society of Korea
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• v.18 no.6
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• pp.691-697
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• 2014

Optical measurements of the morphological and biochemical imaging of phytoplankton are presented. Employing quantitative phase imaging techniques, 3-D refractive index maps and high-resolution 2-D quantitative phase images of individual live phytoplankton are simultaneously obtained without exogenous labeling agents. In addition, biochemical information of individual phytoplankton including volume, mass, and density of individual phytoplankton are also quantitatively obtained from the measured refractive index distributions. We expect the present method to become a powerful tool for the study of phytoplankton.

• Current Optics and Photonics
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• v.1 no.6
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• pp.598-603
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• 2017

Traditional three-dimensional (3-D) laser imaging systems are based on real aperture imaging technology, whose resolution decreases as the range increases. In this paper, we develop a novel 3-D imaging technique based on the synthetic aperture technology in which the imaging resolution is significantly improved and does not degrade with the increase of the range. We consider an imaging laser radar (ladar) system using the floodlight transmitting mode and multi-beam receiving mode. High 3-D imaging resolutions are achieved by matched filtering the linear frequency modulated (LFM) signals respectively in range, synthetic aperture along-track, and the real aperture across-track. In this paper, a novel 3-D imaging signal model is given first. Because of the motion during the transmission of a sweep, the Doppler shift induced by the continuous motion is taken into account. And then, a proper algorithm for the 3-D imaging geometry is given. Finally, simulation results validate the effectiveness of the proposed technique.

• Proceedings of the Korean Society of Medical Physics Conference
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• 1999.11a
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• pp.358-359
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• 1999

• Current Optics and Photonics
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• v.5 no.5
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• pp.532-537
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• 2021

We present a compact endoscopic probe in a needle form which has a fast beam-scanning capability for optical coherence tomography (OCT). In our study, a beam-scanning OCT imaging needle was fabricated with a 26G syringe needle (0.46 mm in outer diameter) and a thin OCT imaging probe based on the stepwise transitional core (STC) fiber. The imaging probe could freely rotate inside the needle for beam scans. Hence, OCT imaging could be performed without rotation or translation of the needle body. In our design, the structural integrity of the needle's steel tubing was preserved for mechanical robustness. Probing the optical signal was performed through the needle's own window formed at the end. For hand-held operation of our imaging needle, a light and compact scanner module (130 g and 45 × 53 × 60 mm³) was devised. Connected to the imaging needle, it could provide rotational actuation driven by a galvanometer. Because of its finite actuation range, our scanner module did not need a fiber rotary joint which might add undesirable complexity. The beam scan speed was 20 Hz and supported 20 frames per second at the maximum for endoscopic OCT imaging.

• Proceedings of the KSRS Conference
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• 2005.10a
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• pp.213-216
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• 2005

A novel hyperspectral imaging spectrometer controlling spatial and spectral resolution individually has been proposed. This imaging spectrometer uses a zoom lens as a telescope and a focusing element. It can change the spatial resolution fixing the spectral resolution or the spectral resolution fixing the spatial resolution. Here, we report the concept of the hyperspectral imaging spectrometer with the novel zooming function and the optical design of a zoom lens as the focusing element. By using lens module and third-order aberration theory, we have presented the initial design of four-group zoom lens with external entrance pupil. And the optimized zoom lens with a focal length of 50 to 150 mm is obtained from the initial design by the optical design software. As a result, the designed zoom lens shows satisfactory performances in wavelength range of 450 to 900 nm as a focusing element in an imaging spectrometer. Furthermore, the collimator lens of the imaging spectrometer is designed through the third-order aberration correction by using an iterative process.