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Comparative Study of Melanin Content in Corneocyte with Skin Color (각질세포 내 멜라닌 정량과 피부색의 비교 연구)

  • Kwak, Taek-Jong;Chang, Min-Youl;Lee, Sang-Min;Park, Sun-Kyoo;Park, Soo-Nam
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.36 no.3
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    • pp.193-198
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    • 2010
  • Melanin is synthesized by the melanocytes in basal layer of epidermis and distributed over all the layers of skin including corneocytes in stratum corneum, outermost layer of the epidermis. Melanin of corneocytes was stained using Fontana-Masson method and quantified by image analysis. The correlation between melanin contents and skin color value was estimated in the skin of 71 Korean women. Melanin covering area (MCA) showed good correlation with $L^*$ value and $ITA^{\circ}$ (Individual Typology Angle) (r = 0.6049, 0.6651, respectively). MCA can be used as new parameter for skin color study and has potential application for evaluating the efficacy of the skin whitening cosmetics.

Evaluation of Van Khan Tooril's castle, an archaeological site in Mongolia, by Ground Penetrating Radar (GPR을 이용한 몽고 유적지 반 칸 투리일의 성 (Van Khan Tooril's castle)의 평가)

  • Khuut, Tseedulam;Sato, Motoyuki
    • Geophysics and Geophysical Exploration
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    • v.12 no.1
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    • pp.69-76
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    • 2009
  • We report an implementation of the Ground Penetrating Radar (GPR) survey at a site that corresponds to a ruined castle. The objective of the survey was to characterise buried archaeological structures such as walls and tiles in Van Khan Tooril's Ruin, Mongolia, by 2D and 3D GPR techniques. GPR datasets were acquired in an area 10mby 9 m, with 10 cm line spacing. Two datasets were collected, using GPR with 500MHz and 800MHz frequency antennas. In this paper, we report the use of instantaneous parameters to detect archaeological targets such as tile, brick, and masonry by polarimetric GPR. Radar polarimetry is an advanced technology for extraction of target scattering characteristics. It gives us much more information about the size, shape, orientation, and surface condition of radar targets. We focused our interpretation on the strongest reflections. The image is enhanced by the use of instantaneous parameters. Judging by the shape and the width of the reflections, it is clear that moderate to high intensity response in instantaneous amplitude corresponds to brick and tiles. The instantaneous phase map gave information about the location of the targets, which appeared as discontinuities in the signal. In order to increase our ability to interpret these archaeological targets, we compared the GPR datasets acquired in two orthogonal survey directions. A good correlation is observed for the alignments of reflections when we compare the two datasets. However, more reflections appear in the north-south survey direction than in the west-east direction. This is due to the electric field orientation, which is in the horizontal plane for north-south survey directions and the horizontally polarised component of the backscattered high energy is recorded.

A new approach to enhancement of ground penetrating radar target signals by pulse compression (파형압축 기법에 의한 GPR탐사 반사신호 분해능 향상을 위한 새로운 접근)

  • Gaballah, Mahmoud;Sato, Motoyuki
    • Geophysics and Geophysical Exploration
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    • v.12 no.1
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    • pp.77-84
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    • 2009
  • Ground penetrating radar (GPR) is an effective tool for detecting shallow subsurface targets. In many GPR applications, these targets are veiled by the strong waves reflected from the ground surface, so that we need to apply a signal processing technique to separate the target signal from such strong signals. A pulse-compression technique is used in this research to compress the signal width so that it can be separated out from the strong contaminated clutter signals. This work introduces a filter algorithm to carry out pulse compression for GPR data, using a Wiener filtering technique. The filter is applied to synthetic and field GPR data acquired over a buried pipe. The discrimination method uses both the reflected signal from the target and the strong ground surface reflection as a reference signal for pulse compression. For a pulse-compression filter, reference signal selection is an important issue, because as the signal width is compressed the noise level will blow up, especially if the signal-to-noise ratio of the reference signal is low. Analysis of the results obtained from simulated and field GPR data indicates a significant improvement in the GPR image, good discrimination between the target reflection and the ground surface reflection, and better performance with reliable separation between them. However, at the same time the noise level slightly increases in field data, due to the wide bandwidth of the reference signal, which includes the higher-frequency components of noise. Using the ground-surface reflection as a reference signal we found that the pulse width could be compressed and the subsurface target reflection could be enhanced.

Magnetic Resonance Imaging Feature of Bacterial Meningitis in a Neonate Hanwoo Calf (한우 송아지에서 세균성 뇌막염의 자기공명영상)

  • Cho, Young-Kwon;Kim, Jin-Won;Kim, Jae-Hoon;Kim, Jae-Hoon;Lee, Ki-Chang
    • Journal of Veterinary Clinics
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    • v.26 no.6
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    • pp.650-654
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    • 2009
  • A 1-week-old, male Korean native calf with acute clinical signs of depression, mild diarrhea, ataxia, recumbency and tremor was referred to Chonbuk Veterinary Medical Center of Chonbuk National University. Vision loss and cornea edema were also observed on physical examination. The patient had been deteriorated with nystagumus, strabisumus and opisthtonus. Blood cell count test and blood biochemistry test revealed remarkable leukocytosis, and hypoalbuminemia and increased blood urea nitrogen. No remarkable findings were observed on radiography. On magnetic resonance imaging study, there were enlarge lateral, third, and forth ventricles. The cortical grey and subcortical white matter of left temporal lobe showed hypointense on T1-weighted images and hyperintense on T2-weighted images, and slightly enhanced on contrast-enhanced T1-weighted images. Escherichia coli strain was identified from cerebrospinal fluid sample. Palliative treatment was attempted but the neonatal calve was expired three days after admission. Severe multifocal fibrino-suppurative meningitis with Escherichia coli infection was confirmed histopathologically.

Structural Characterization of Bismuth Zinc Oxide Thin Films Grown by Plasma-Assisted Molecular Beam Epitaxy (플라즈마분자선에피탁시법으로 성장한 산화비스무스아연 박막의 구조특성)

  • Lim, Dong-Seok;Shin, Eun-Jung;Lim, Se-Hwan;Han, Seok-Kyu;Lee, Hyo-Sung;Hong, Soon-Ku;Joeng, Myoung-Ho;Lee, Jeong-Yong;Cho, Hyung-Koun;Yao, Takafumi
    • Korean Journal of Materials Research
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    • v.21 no.10
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    • pp.563-567
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    • 2011
  • We report the structural characterization of $Bi_xZn_{1-x}O$ thin films grown on c-plane sapphire substrates by plasma-assisted molecular beam epitaxy. By increasing the Bi flux during the growth process, $Bi_xZn_{1-x}O$ thin films with various Bi contents (x = 0~13.17 atomic %) were prepared. X-ray diffraction (XRD) measurements revealed the formation of Bi-oxide phase in (Bi)ZnO after increasing the Bi content. However, it was impossible to determine whether the formed Bi-oxide phase was the monoclinic structure ${\alpha}-Bi_2O_3$ or the tetragonal structure ${\beta}-Bi_2O_3$ by means of XRD ${\theta}-2{\theta}$ measurements, as the observed diffraction peaks of the $2{\theta}$ value at ~28 were very close to reflection of the (012) plane for the monoclinic structure ${\alpha}-Bi_2O_3$ at 28.064 and the reflection of the (201) plane for the tetragonal structure ${\beta}-Bi_2O_3$ at 27.946. By means of transmission electron microscopy (TEM) using a diffraction pattern analysis and a high-resolution lattice image, it was finally determined as the monoclinic structure ${\alpha}-Bi_2O_3$ phase. To investigate the distribution of the Bi and Bi-oxide phases in BiZnO films, elemental mapping using energy dispersive spectroscopy equipped with TEM was performed. Considering both the XRD and the elemental mapping results, it was concluded that hexagonal-structure wurtzite $Bi_xZn_{1-x}O$ thin films were grown at a low Bi content (x = ~2.37 atomic %) without the formation of ${\alpha}-Bi_2O_3$. However, the increased Bi content (x = 4.63~13.17 atomic %) resulted in the formation of the ${\alpha}-Bi_2O_3$ phase in the wurtzite (Bi)ZnO matrix.

New Fiduciary Plate and Orientation Marker for High Energy Radiation Therapy (고에너지 방사선치료의 정도관리를 위한 Fiduciary Plate 및 Orientation Marker의 개발)

  • Wu Hong-Gyun;Huh Sun Nyung;Kim Hak Jae
    • Radiation Oncology Journal
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    • v.22 no.1
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    • pp.69-75
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    • 2004
  • Purpose : A new fiduciary plate and orientation marker have been devised to assist the quality assurance (QA) procedures for port films in radiation therapy department. The plate is used in conjunction with the film/cassette combination during weekly QA procedures, at Seoul National University Hospital (SNUH), in order to verify treatment fields in high radiation therapy. Materials and Methods : A new fiduciary plate was fabricated using an acrylic plate, cerrobend, standard blocking tray and mercury. The acrylic plate had the dimension of $1{\times}25{\times}25$ cm, with two fiduciary markers. The plate was rigidly attached onto the standard blocking tray, thus making it easier to set the fiduciary plate to the center on the radiation field on the linear accelerator. The plate had two 2-mm vertical and horizontal lines, with the minor scales in 2-cm steps. The orientation marker was a small mercury filled disk, which was inserted into the plate. Results : The geometrical structure of the lines in the plate makes it easier to correlate two different images between the simulation and port films. The marker clearly indicated the orientation of the film, for example, the anterior, posterior, left, right and various oblique orientations, without the placement of a conventional orientation marker. Also, the new orientation marker could easily be applied to the simulator by placing the small orientation marker onto the image intensifier or in front of the film/cassette holder. Conclusions : The new fiduciary plate appears to be useful in verifying the treatment fields, and the new orientation marker makes the film orientation simple, which is expected to lower the block fabrication errors.

Evaluation of the heart and lung dosimetric parameters in deep inspiration breath hold using 3D Slicer

  • Eskandari, Azam;Nasseri, Shahrokh;Gholamhosseinian, Hamid;Hosseini, Sare;Farzaneh, Mohammad Javad Keikhai;Keramati, Alireza;Naji, Maryam;Rostami, Atefeh;Momennezhad, Mehdi
    • Radiation Oncology Journal
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    • v.38 no.1
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    • pp.68-76
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    • 2020
  • Purpose: The present study was conducted to compare dosimetric parameters for the heart and left lung between free breathing (FB) and deep inspiration breath hold (DIBH) and determine the most important potential factors associated with increasing the lung dose for left-sided breast radiotherapy using image analysis with 3D Slicer software. Materials and Methods: Computed tomography-simulation scans in FB and DIBH were obtained from 17 patients with left-sided breast cancer. After contouring, three-dimensional conformal plans were generated for them. The prescribed dose was 50 Gy to the clinical target volume. In addition to the dosimetric parameters, the irradiated volumes and both displacement magnitudes and vectors for the heart and left lung were assessed using 3D Slicer software. Results: The average of the heart mean dose (Dmean) decreased from 5.97 to 3.83 Gy and V25 from 7.60% to 3.29% using DIBH (p < 0.001). Furthermore, the average of Dmean for the left lung was changed from 8.67 to 8.95 Gy (p = 0.389) and V20 from 14.84% to 15.44% (p = 0.387). Both of the absolute and relative irradiated heart volumes decreased from 42.12 to 15.82 mL and 8.16% to 3.17%, respectively (p < 0.001); however, these parameters for the left lung increased from 124.32 to 223.27 mL (p < 0.001) and 13.33% to 13.99% (p = 0.350). In addition, the average of heart and left lung displacement magnitudes were calculated at 7.32 and 20.91 mm, respectively. Conclusion: The DIBH is an effective technique in the reduction of the heart dose for tangentially treated left sided-breast cancer patients, without a detrimental effect on the left lung.

An Analysis on the Importance of Planning Indicator of Traffic Calming Technique for Walk Safety - Focusing on Physical Side - (보행안전을 위한 교통정온화(Traffic Calming) 계획지표의 중요도 분석 - 물리적인 측면을 중심으로 -)

  • Yoon, Sanghoon;Choi, Hyoungsun;Lee, Joohyung
    • Journal of the Society of Disaster Information
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    • v.11 no.4
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    • pp.570-580
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    • 2015
  • In the study, planning indicator that should be considered in applying traffic calming technique was derived, and it was intended to analyze the importance of indicator that should most considered in planning traffic calming technique through AHP analysis on the basis of it. The result of planning indicator may be summarized by dividing into road section and crossing section. In road section, hump (0.35) for equipment stimulating reduction of speed, hump image/fort (0.31) for visual control equipment, and slalom type road (0.52) for chicane, and bollard (0.47) for blocking passing route are shown to be the most important and come before anything. In crossing section, signal indicator (0.33) for visual control equipment, rumble strip (0.44) for equipment stimulating reduction of speed, zigzag type road (0.65) for chicane, and blocking going straight at crossing (0.45) for blocking passing route are shown to be the most important and come before anything. The result of the study is judged to be used for basic material in applying traffic calming technique and establishing policy hereafter.

Scientific Investigation for Conservation Methodology of Bracket Mural Paintings of Daeungjeon Hall in Jikjisa Temple (직지사 대웅전 포벽화 보존방안을 위한 과학적 조사)

  • Lee, Hwa Soo;Kim, Seol Hui;Han, Kyeong Soon
    • Journal of Conservation Science
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    • v.34 no.2
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    • pp.107-118
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    • 2018
  • This report does studied for making the method of conserving bracket murals in Daeungjeon of Jikjisa Temple, through the scientific way. Results of evaluated the conservation status at the braket mural paintings, most serious damage is structural damage like cracks, breakage, and delamination. After optical investigation, a characteristic point wasn't found such as underdrawing or traces of a coat of paint. The ultrasonic examination speed by each wall painting was measured from about 195.8 m/s to 392.7 m/s, according to the location of the surface, and it was able to compare the surface properties according to the location. In Infrared-thermal image measurement shows that wall layer separation and paint layer delamination are closely detected, therefore it was able to judge of damage on the objective way. Material analysis revealed that the walls were made by sand and weathering soil. The wall layer combined sand with less than fine sand size by nearly 5:5, and the finishing layer was found to have mixed medium sand and fine sand at approximately 6:4 rates. However, In case of finishing layer, mixing ratios of sizes less than very fine sand were found to be significantly lower than wall. Therefore, it is estimated that the plysical damage such as the separation between the layers of the walls created in the braket mural paintings, is continuously caused by changes in the internal stresses and volume ratio caused by the density differences between the wall and the finishing layers.

The effect of patient position on dose in radiation therapy of liver cancer (환자 자세가 간의 방사선 치료 시 선량에 미치는 영향)

  • Jung, Won Seok;Kim, Ju Ho;Kim, Young Jae;Shin, Ryung Mi;Oh, Jeong Hun;Jeong, Geon A;Jo, Jun Young;Kim, Gi Chul;Choi, Tae Kyu
    • The Journal of Korean Society for Radiation Therapy
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    • v.26 no.1
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    • pp.1-9
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    • 2014
  • Purpose : To analyze tumor's movement and volume change from changing position in order to minimize movement caused by breathing. Materials and Methods : We conducted survey of 14 patients with HCC(Hepatocellular carcinoma). Patient immobilization device was made in two ways(Supine position, prone position) and from image acquisition, tumor's movement, volume and dose are analyzed. Results : The mean movement of target(LR, Left-right) in supine position and prone position was $2.76{\pm}1.25mm$, $2.21{\pm}0.93mm$. AP(Anterior-posterior) and SI(Superior-inferior) was $4.02{\pm}1.63mm$, $11.56{\pm}3.08mm$, $3.36{\pm}1.17mm$, $7.45{\pm}1.96mm$. Treatment volume was decreased and normal liver volume was increased in prone position. Conclusion : We could reduce the margin of the treatment volume by minimizing the movement of liver caused by breathing. Especially in prone position, it is considered to be able to decrease the movement of the liver and increase normal liver volume.