• Title/Summary/Keyword: iSC

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Introduction of Clinical and Laboratory Standards Institute Antibiotic Susceptibility Testing Subcommittee Meeting (Clinical and Laboratory Standards Institute의 항생제 감수성 검사 소위원회 회의 소개)

  • Chang, Chulhun L.
    • Annals of Clinical Microbiology
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    • v.21 no.4
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    • pp.69-74
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    • 2018
  • Laboratory medicine is a specialized division that supports physicians in the care of patients by providing rapid and accurate in vitro diagnostic tests. Standardization of every component of a specific test is essential for producing accurate results. The Clinical and Laboratory Standards Institute (CLSI) was founded to develop a formal consensus process for standardization in 1968, and has been publishing standards and guidelines covering all aspects of clinical, research, and other laboratory work. CLSI guidelines are widely used around the world for standardization. The CLSI antimicrobial susceptibility testing subcommittee (AST SC) consists of 6 standing and many ad hoc working groups. Members of the AST SC review submitted proposals and suggestions, decide on approving these submissions in face-to-face meetings held twice a year, and revise CLSI documents accordingly. As these face-to-face meetings are open to anyone who registers to attend, I strongly encourage the members of our Society to attend and actively participate in document development.

Knowledge Domain and Emerging Trends of Intelligent Green Building and Smart City - A Visual Analysis Using CiteSpace

  • Li, Hongyang;Dai, Mingjie
    • International conference on construction engineering and project management
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    • 2017.10a
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    • pp.24-31
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    • 2017
  • As the concept of sustainability becomes more and more popular, a large amount of literature have been recorded recently on intelligent green building and smart city (IGB&SC). It is therefore needed to systematically analyse the existing knowledge structure as well as the future new development of this domain through the identification of the thematic trends, landmark articles, typical keywords together with co-operative researchers. In this paper, Citespace software package is applied to analyse the citation networks and other relevant data of the past eleven years (from 2006 to 2016) collected from Web of Science (WOS). Through this, a series of professional document analysis are conducted, including the production of core authors, the influence made by the most cited authors, keywords extraction and timezone analysis, hot topics of research, highly cited papers and trends with regard to co-citation analysis, etc. As a result, the development track of the IGB&SC domains is revealed and visualized and the following results reached: (i) in the research area of IGB&SC, the most productive researcher is Winters JV and Caragliu A is most influential on the other hand; (ii) different focuses of IGB&SC research have been emerged continually from 2006 to 2016 e.g. smart growth, sustainability, smart city, big data, etc.; (iii) Hollands's work is identified with the most citations and the emerging trends, as revealed from the bursts analysis in document co-citations, can be concluded as smart growth, the assessment of intelligent green building and smart city.

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Top Electrode Engineering in Organic Light-Emitting Devices Formed by Soft Contact Lamination

  • Lee, Tae-Woo;Zaumseil, Jana;Bao, Zhenan;Hsu, Julia W.P.;Rogers, John A.
    • 한국정보디스플레이학회:학술대회논문집
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    • 2004.08a
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    • pp.348-351
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    • 2004
  • We describe a new approach for building organic light-emitting diodes (OLEDs), which is based on physical lamination (i.e. soft contact lamination (ScL)) of thin metal electrodes supported by an elastomeric layer (polydimethylsiloxane) against an electroluminescent organic. We find that the devices fabricated have much better performance than those constructed with conventional vacuum deposition process. In addition, the ScL is intrinsically compatible with the technique of soft lithograph so that it is easy to build patterned OLEDs with feature sizes into the nanometer regime.

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A Study on ZnSe/GaAs Heterojunction Solar Cells Grown by MBE (MBE법으로 제작한 ZnSe/GaAs 이종접합 태양전지에 관한 연구)

  • Lee, Hong-Chan;Lee, Sang-Tae;Oh, Jin-Suck;Kim, Yoon-Sik;Chang, Ji-Ho
    • Proceedings of the Korean Society of Marine Engineers Conference
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    • 2006.06a
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    • pp.289-290
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    • 2006
  • We report a study of Zn(S)Se/GaAs heterojunction solar cells grown by molecular beam epitaxy (MBE). Zn(S)Se/GaAs heterostructures prepared under different conditions were characterized in-situ by reflection high-energy electron diffraction (RHEED). Structural and electrical properties were investigated with double crystal X-ray diffraction and current-voltage characteristics, respectively. The fabricated $n-ZnS_{0.07}Se_{0.93}/p-GaAs$ solar cell (SC #2) exhibited open circuit voltage($V_{oc}$) of 0.37 V, short circuit current($I_{sc}$) of $1.7{\times}10^{-2}$ mA, fill factor of 0.62 and conversion efficiency of 7.8 % under 38.5 $mW/cm^2$ illumination.

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Analysis of a breakdown in 154 kV STATCON Bank condenser cell (154 kV STATCON Bank용 콘덴서 셀 절연파괴 원인분석)

  • Ju, H.J.;Kweon, D.J.;Kang, Y.W.;Shim, E.B.;Lee, S.I.;Lee, H.H.
    • Proceedings of the KIEE Conference
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    • 2003.11a
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    • pp.388-391
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    • 2003
  • 154 kV 변전소에 설치 운전 중인 SC Bank 콘덴서 셀의 절연파괴 고장이 빈번하게 발생되어 전력계통의 운용 및 변전소 운전에 지장을 주는 사례가 많이 발생하였다. 따라서 이의 고장원인 진단을 통하여 대책수립을 하고자 EMTP(Electro-Magnetic Transient Program)를 이용하여 SC Bank의 정상상태시 과전압, 과전류에 의한 소손현상을 검토하고, 계통조건에 따른 공진점변화와 고조파에 따른 이상전압 및 콘덴서 셀 전압의 상승 현상을 검토 분석하고, 고조파 성분에 따른 과전압 및 과전류를 분석하여 대책을 제시한 사례연구의 결과이다.

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COMPARISON AMONG SEVERAL ADJACENCY PROPERTIES FOR A DIGITAL PRODUCT

  • Han, Sang-Eon
    • Honam Mathematical Journal
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    • v.37 no.1
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    • pp.135-147
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    • 2015
  • Owing to the notion of a normal adjacency for a digital product in [8], the study of product properties of digital topological properties has been substantially done. To explain a normal adjacency of a digital product more efficiently, the recent paper [22] proposed an S-compatible adjacency of a digital product. Using an S-compatible adjacency of a digital product, we also study product properties of digital topological properties, which improves the presentations of a normal adjacency of a digital product in [8]. Besides, the paper [16] studied the product property of two digital covering maps in terms of the $L_S$- and the $L_C$-property of a digital product which plays an important role in studying digital covering and digital homotopy theory. Further, by using HS- and HC-properties of digital products, the paper [18] studied multiplicative properties of a digital fundamental group. The present paper compares among several kinds of adjacency relations for digital products and proposes their own merits and further, deals with the problem: consider a Cartesian product of two simple closed $k_i$-curves with $l_i$ elements in $Z^{n_i}$, $i{\in}\{1,2\}$ denoted by $SC^{n_1,l_1}_{k_1}{\times}SC^{n_2,l_2}_{k_2}$. Since a normal adjacency for this product and the $L_C$-property are different from each other, the present paper address the problem: for the digital product does it have both a normal k-adjacency of $Z^{n_1+n_2}$ and another adjacency satisfying the $L_C$-property? This research plays an important role in studying product properties of digital topological properties.

Scavenging Capacities of DPPH and ABTS Free Radicals and Anti-inflammatory Activities of Ethanol Extracts and their Fractions from Sophora tonkinensis

  • Eun Sun Moon;Ji Yoon Lee;Seongdae Kim;Chang Won Choi
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2021.04a
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    • pp.46-46
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    • 2021
  • The first purpose of this study was to evaluate the scavenging capacity (SC) of DPPH and ABTS free radicals for ethanol extract (STR-E) and its active fractions from Sophora tonkinensis root (STR). Four different fractions from STR-E were prepared by using different types of solvents such as chloroform (STR-E-C), ethyl acetate (STR-E-EA), n-butanol (STR-E-B), and water (STR-E-W). STR-E-C showed the highest value of total phenolic content, while STR-E showed the highest value of total flavonoid and terpenoid content. In STR-E and its four fractions, STR-E-EA showed the strongest SC with the lowest SC50 values of the DPPH radicals and ABTS radicals. The second purpose of this study was to evaluate anti-inflammatory activity in the lipopolysaccharide (LPS)-induced RAW 264.7 macrophages treated with STR-E, STR-E-C, and STR-E-EA, respectively. No cytotoxic effect to RAW 264.7 cells was observed at 20 ~ 25 ㎍/ml of STR-E, 10 ㎍/ml of STR-E-C, and 5 ㎍/ml of the STR-E-EA, presenting cell viability values close to that of the untreated control (100%). STR-E, STR-E-C, and STR-E-EA significantly suppressed the LPS-induced nitric oxide (NO) in a dose-dependent manner. Results of reverse-transcription (RT)-qPCR analysis showed that the peak mRNA levels of IL-1β, TNF-α, iNOS, IL-6, and IL-10 were observed in the LPS-stimulated macrophages at 4 h, 2 h, 12 h, 12 h, and 12 h, respectively. The peak mRNA levels of IL-1β, TNF-α, iNOS, and IL-6 were significantly reduced in the LPS-stimulated macrophages co-treated with 20 ㎍/ml and 25 ㎍/ml of STR-E, respectively. In the case of IL-10, its peak mRNA level slightly increased without statistical significance. Compared with the LPS-stimulated macrophages, the peak mRNA levels of IL-1β, TNF-α, iNOS, and IL-6 reduced in the LPS-stimulated macrophages co-treated with 10 ㎍/ml and 20 ㎍/ml of STR-E-C, respectively. In contrast, the peak mRNA level of IL-10 significantly increased at 8 h. Compared with the LPS-stimulated macrophages, the peak mRNA levels of IL-1β, TNF-α, iNOS, and IL-6 reduced in the LPS-stimulated macrophages co-treated with 5 ㎍/ml and 10 ㎍/ml of STR-E-EA, respectively. In contrast, the peak mRNA level of IL-10 increased at 4 h. Taken together, our data indicated that STR-E, STR-E-C, and STR-E-EA activate macrophages to secrete both pro-inflammatory and anti-inflammatory cytokines.

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Effects of Glucagon-Like Peptide-2-Expressing Saccharomyces cerevisiae Not Different from Empty Vector

  • Zhong, Xi;Liang, Guopeng;Cao, Lili;Qiao, Qi;Hu, Zhi;Fu, Min;Bo, Hong;Wu, Qin;Liang, Guanlin;Zhang, Zhongwei;Zhou, Lin
    • Journal of Microbiology and Biotechnology
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    • v.29 no.10
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    • pp.1644-1655
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    • 2019
  • Saccharomyces cerevisiae (S. cerevisiae) and glucagon-like peptide-2 (GLP-2) have been employed to improve the intestinal development of weaned animals. The goal of this study was to determine whether either exogenous S. cerevisiae or GLP-2 elicits major effects on fecal microbiotas and cytokine responses in weaned piglets. Ninety-six piglets weaned at 26 days were assigned to one of four groups: 1) Basal diet (Control), 2) empty vector-harboring S. cerevisiae (EV-SC), 3) GLP-2-expressing S. cerevisiae (GLP2-SC), and 4) recombinant human GLP-2 (rh-GLP2). At the start of the post-weaning period (day 0), and at day 28, fecal samples were collected to assess the bacterial communities via sequencing the V1-V2 region of the 16S-rRNA gene, and piglets' blood was also sampled to measure cytokine responses (i.e., IL-$1{\beta}$, TNF-${\alpha}$, and IFN-${\gamma}$). This study revealed that, on the one hand, although S. cerevisiae supplementation did not significantly alter the growth of weaned piglets, it induced increases in the relative abundances of two core genera (Ruminococcaceae_norank and Erysipelotrichaceae_norank) and decreases in the relative abundances of two other core genera (Lachnospiraceae_norank and Clostridiale_norank) and cytokine levels (IL-$1{\beta}$ and TNF-${\alpha}$) (p < 0.05, Control vs EV-SC; p < 0.05, rh-GLP2 vs GLP2-SC). On the other hand, GLP-2 supplementation had no significant influence on fecal bacterial communities and cytokine levels, but it produced better body weight and average daily gain (p < 0.05, Control vs EV-SC; p < 0.05, rh-GLP2 vs GLP2-SC). Therefore, altered fecal microbiotas and cytokine response effects in weaned piglets were due to S. cerevisiae rather than GLP-2.

Anti-Inflammatory Effects of the Mixture of Sorbus commixta, Urtica dioica, Phyllostachys nigra, and Rhus semialata Gall Extracts on LPS-induced Inflammation in HaCaT Cells (각질형성세포에서 LPS로 유도된 염증반응에 대한 마가목, 쐐기풀, 죽여 및 오배자 혼합추출물의 항염 효과)

  • Lee, Kyung-Eun;Nam, Jin-Ju;Kim, Seon-Mi;Kim, Han-Kon;Moon, Seong-Joon;Youm, Jong-Kyung
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.40 no.1
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    • pp.45-54
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    • 2014
  • Lipopolysaccharide (LPS)-induced inflammatory responses in the HaCaT keratinocyte cell line produce proinflammatory cytokines, such as interleukin-1${\alpha}$(IL-1${\alpha}$), tumor neurosis factor-${\alpha}$ (TNF-${\alpha}$), interleukin-6 (IL-6), and interleukin- 8 (IL-8) and also increase the expression of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandins E2 (PGE2). In this study, we developed new natural ingredients for cosmetics that inhibit the pro-inflammatory responses induced by LPS in HaCaT cells. The mixture of Sorbus commixta (SC), Urtica dioica (UD), Phyllostachys nigra (PN), and Rhus semialata gall (RS) extracts blocked the increase of TNF-${\alpha}$ IL-1${\alpha}$ IL-6, and IL-8. The increase of COX-2, iNOS, and PGE2 were also blocked by it. Finally, the mixture inhibited skin irritation induced by sodium lauryl sulfate (SLS), when applied on skin through IQ chamber$^{(R)}$. In conclusion, these results show that the mixture of SC, UD, PN, and RS can be used as a primary ingredient to alleviate skin irritation when cosmeceutical products are developed for sensitive skin.

Assessment of Soil Aggregates and Erodibility Under Different Management Practices in the Mountainous Soils (산지에서 영농방법에 따른 토양입단과 침식성 평가)

  • Joo, Jin-Ho;Yang, Jae-E;Kim, Jeong-Je;Jung, Yeong-Sang;Choi, Joong-Dae;Yun, Sei-Young;Ryu, Kwan-Shig
    • Korean Journal of Soil Science and Fertilizer
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    • v.33 no.2
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    • pp.61-70
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    • 2000
  • Soil erosion in the hilly and mountainous uplands in the Daekwanryong area, Kangwon-Do, were investigated through a field plot experiment. The plot size was 15m long and 2.5m wide with the average slope of 12.5 percents. Soil erodibility factor (K), surface coverage (SC), soil aggregate percentage and wind erodibility (I) were evaluated in the mountainous soils under different management practices for corn and potato cultivations. Soil erodibility factor (K) was greater in upper part than in lower part of the plots. Surface coverage (SC) values ranged from 0.01 to 0.84 depending on the amounts of crop residues. Soils having a greater crop residue in surface were less subjected to soil erosion. SC values after corn harvest were 0.4 to 0.8, while those after potato harvest were 0.4 to 0.5, indicating potato might be better than corn for erosion control. Soil aggregate percentages of the experimental plots ranged from 49.7 to 79.8%. Those were higher in potato-cultivated plots with higher surface coverage, organic fertilizer treatment and contour tillage. Soil aggregate percentage of potato-cultivated plots was significantly correlated to crop residue coverage after harvest. The dried soil aggregate percentage, showing the ranges of 26.4 to 56.4%, were higher in the plots with the increased crop residue incorporation. Wind erodibility (I) of the soil was decreased with increasing surface coverage. When soil had 26.4% of the dried aggregate percentage, wind erodibility was estimated to be $183Mgha^{-1}$ which was equivalent to soil loss of $0.5Mg\ha^{-1}day^{-1}$.

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