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단일 3차 의료기관에 내원한 당뇨병성 족부병변 환자의 창상 배양검사를 통한 세균 검출 현황 (The Current Status of Bacterial Identification by Wound Culture for Diabetic Foot Lesions in a Single Tertiary Hospital in South Korea)

  • 정성윤;이명진;이승엽;이상윤
    • 대한족부족관절학회지
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    • 제25권2호
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    • pp.100-107
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    • 2021
  • Purpose: The present study aimed to develop guidelines regarding initial choice of antibiotics for diabetic foot ulcers (DFU) by investigating bacterial isolates. Materials and Methods: This study included 223 DFU patients that visited a single tertiary hospital and underwent bacterial culture between January 2016 and February 2020. The study was conducted in two parts: 1) to compare bacterial isolates and wound healing according to comorbidities such as chronic kidney disease (CKD) and peripheral artery disease (PAD), and 2) to compare bacterial isolates according to wound depth using the Wagner classification. Results: Of the 223 patients, 43 had CKD (group A), 56 had PAD (group B), 30 had CKD and PAD (group C), and 94 had none of these comorbidities (group D). The isolation rate for multidrug-resistant gram-negative bacteria (MRGNB) and gram-negative to gram-positive bacteria ratio were highest in group C (p=0.018, p=0.038), and the proportion that achieved wound healing was lowest in group C (p<0.001). In the second part of the study, subjects were classified into 5 grades by wound depth using the Wagner classification; 13 grade I, 62 grade II, 60 grade III, 70 grade IV, and 17 grade V. No significant difference was observed between these grades in terms of isolation rates or gram-negative to gram-positive bacteria ratios. Conclusion: This study suggests antibiotics that cover gram-negative bacteria including MRGNB produces better results in the presence of CKD and PAD and that initial antibiotic choice should be based on the presence of CKD and PAD rather than wound depth.

Immunomodulatory effect of Tinospora cordifolia and Centella asiatica and its modulation on cyclophosphamide challenge

  • Siddiqui, NA;Ali, Mohd;Singh, Shobhna
    • Advances in Traditional Medicine
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    • 제8권4호
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    • pp.380-385
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    • 2008
  • Ethanolic extracts of T. cordifolia and C. asiatica were evaluated for immunostimulatory effect in mice against sheep RBCs as antigen by three models viz. delayed type hypersensitivity reaction, ercent change in neutrophil count and haemagglutination titre. Immunostimulatory effect in the presence of immunosuppressant agent, cyclophosphamide (100 mg/kg, i.p.) was also investigated. T. cordifolia and C. asiatica significantly (p < 0.001, p < 0.05 respectively) enhanced foot pad thickness when measured after 24 hours of sheep RBC antigen challenge. Both the plant materials increased foot pad thickness even after being subjected to immunosuppressant exposure. T. cordifolia revealed enhanced neutrophil counts, while C. asiatica had no significant effect on neutrophil counts. T. cordifolia exhibited significantly (P < 0.01) elevated neutrophil levels even in the presence of cyclophosphamide administration. Both the plants exhibited humoral antibody response, as haemagglutination titre values were significantly high as compared to control. T. cordifolia and C. asiatica could combat immunosuppressant effect of cyclophosphamide (P < 0.01). This suggests that T. cordifolia and C. asiatica can be regarded as biological response modifiers and can be utilized for the development of immunostimulating agent among plant sources.

이진 알고리즘을 이용한 변형 시리얼테스트 설계에 관한 연구 (Design variation serial test using binary algorithm)

  • 최진석;이성주
    • 한국지능시스템학회논문지
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    • 제20권1호
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    • pp.76-80
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    • 2010
  • 급변하는 정보의 홍수 속에서 정보의 보안과 이를 가공하고 전송하는 것이 중요한 과제로 떠오르고 있다. 초기 정보보호이론과 암호화 전송단계에서는 간단한 치환과 수학적 계산 알고리즘을 적용한 암 복호화 과정을 이용하였다. 완벽한 정보보호는 One-time pad를 이용하는 것이나 이를 적용하기에는 하드웨어와 금전적 손실이 너무 크기에 실난수가 아닌 난수성을 만족하는 의사난수를 사용하고 있다. 본고에서 제안하는 변형 시리얼 테스트는 의사난수성을 입증하는 테스트 중 시리얼테스트에서 변형된 것으로 연산속도와 효율성 면에서 보다 더 강력한 난수성임을 입증하고 있다.

WWDC2012와 Google I/O를 통해 본 모바일 OS의 변화

  • 신재경
    • 정보와 통신
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    • 제29권9호
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    • pp.3-9
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    • 2012
  • 본고에서는 WWCD2012에서 발표한 iOS 6.0에서는 Maps/Siri/Facetime/Passbook 등의 자체 서비스 강화, Major Service의 Embedded를 통한 Application 기능 강화 등에 초점을 맞추어 개선점을 찾아가고 있다. 이에 대해 Google도 Siri에 대응되는 Google Now를 발표하고, iPad에 대응되는 넥서스7를 발표하였다. 지금까지는 자체 개선점에 주력하며 기능을 하나씩 개선하는데 주력한 것에 비해서 2012년에는 안정적이고 빠른 UI 및 Frameworks의 개선을 제시하면서 사실상 유사한 품질을 제공하려 노력하고 있으며, 경쟁 OS 대비 경쟁을 의식한 기능과 서비스를 계속 제안할 것이다.

나로우주센터 발사장에서 나로호 GPS 수신기 시스템의 운용 (Operation of the GPS Receiver System for KSLV-I on the Launch Site at Naro Space Center)

  • 권병문;문지현;신용설;최형돈;조광래
    • 한국항공우주학회지
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    • 제38권7호
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    • pp.737-745
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    • 2010
  • 본 논문은 고흥에 위치한 나로우주센터 발사장에 나로호가 발사대기하고 있을 때에 나로호에 탑재된 GPS 수신기 시스템의 운용결과에 대하여 다룬다. 나로호가 발사대에서 수직으로 기립하고 있는 동안에 GPS 수신기 시스템을 포함한 나로호의 모든 탑재장비들은 나로호의 이륙 직전까지 동작상태와 성능이 점검되어야 한다. 나로호에 탑재된 GPS 수신기는 기체 표면에 설치된 3개의 패치형 GPS 안테나와 연결된다. 각각의 GPS 안테나에서 수신된 GPS 위성신호를 바탕으로 나로호가 발사대에 발사대기중일 때에 발사장 환경에 의해 GPS 수신기에서 관찰된 신호간섭과 다중경로로 인해 발생한 현상 등을 분석한다.

Brass fillers in friction composite materials: Tribological and brake squeal characterization for suitable effect evaluation

  • Kchaou, Mohamed;Sellami, Amira;Abu Bakar, Abd. Rahim;Lazim, Ahmad Razimi Mat;Elleuch, Riadh;Kumar, Senthil
    • Steel and Composite Structures
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    • 제19권4호
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    • pp.939-952
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    • 2015
  • In this paper, brake pad performance of two organic matrix composites namely, Sample 1 (contains no brass filler) and Sample 2 (contains 1.5% brass filler), is studied based on tribological and squeal noise behavior. In the first stage, a pin-on-disc tribometer is used to evaluate the frictional behavior of the two pads. On the following stage, these pads are tested on squeal noise occurrence using a drag-type brake dynamometer. From the two type of tests, the results show that; (i) brass fillers play a dual role; firstly as reinforcing element of the brake pad providing primary contact sites, and secondly as solid lubricant by contributing to the formation of a layer of granular material providing velocity accommodation between the pad and the disc; (ii) brass fillers contribute to friction force stabilization and smooth sliding behavior; (iii) the presence of small weight quantity of brass filler strongly contributes to squeal occurrences; (iv) there is close correlation between pin-on-disc tribometer and brake dynamometer tests in terms of tribological aspect.

뇨분석 시스템 개발에 관한 연구 (A Study on the Development of Urine Analyzer System)

  • 이승진;최병철;김광년;홍순익;김재호;김재형;전계록
    • 대한의용생체공학회:학술대회논문집
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    • 대한의용생체공학회 1997년도 춘계학술대회
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    • pp.303-308
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    • 1997
  • In this paper, we analyzed the spectroscopic properties of strip to analyzer urine qualitatively & quantitatively and make urine analyzer system stable by spectroscopy, and research the property of preamplifier unit. The analysis of spectroscopic properties of 10 pads in the strip is used for determine the wave length of light source of optic detector unit and used for basic materials which are necessary that we develop the algorithm analyzing the density grade of pad accurately. We make preamplifier unit by using the current to frequency method to measure the distribution of pad color. We implemented urine analyzer system. This system's hardware is composed of measuring unit for detect of distribution density of strip pad, main processing unit, communication unit, interface device, thermal printer, and indicator. The software consists of the program which manage the argument of test, proportion initial value of urine analyzer and calibrate analyzed result.

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프로세스 고속 경량 원심 압축기의 로터다이나믹 안정성 강화를 위한 설계해석 - Part II: 로터다이나믹 안정성 개선 (Design Analysis for Enhancing Rotordynamic Stability of Process High-Speed Light weight Centrifugal Compressor - Part II: Improvements to Rotordynamic Stability)

  • 이안성
    • Tribology and Lubricants
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    • 제30권1호
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    • pp.9-14
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    • 2014
  • In this Part II study, rotordynamic stability analyses were carried out to confirm improvements to the stability of a process high-speed lightweight centrifugal compressor, depending on the effects of tilting pad journal bearing designs. The bearing design variables considered were the clearances, LBPs, LOPs, and preloads. The results showed that the rotordynamic stability of the subject compressor rotor-bearing system improves exactly in accordance with the effects of the bearing design variables, which were determined in the preceding Part I study, owing to reduced bearing stiffnesses. Specifically, it was confirmed that the stability of the rotor system can be greatly improved by increasing both the machined and assembled bearing clearances, but there were no stability improvements by simply changing from an LBP to an LOP design. In addition, it was confirmed that for given fixed machined bearing clearances, the stability can be additionally improved by decreasing the preloads, i.e., by increasing the assembled clearances. In conclusion, it may be necessary to improve the designs of the original tilting pad bearings to obtain a sufficient margin of rotordynamic stability against a possible aerodynamic cross-coupled stiffness in a process high-speed centrifugal compressor. Thus, increasing the machined and assembled bearing clearances and decreasing the preload could be effective solutions.

모바일 클라우드 컴퓨팅 소프트웨어 기술

  • 이성원;김현준
    • 정보와 통신
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    • 제27권6호
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    • pp.35-43
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    • 2010
  • 본 고에서는 최근 IT 분야의 주요 이슈로 부각되고 있는 클라우드 컴퓨팅 환경과 관련한 소프트웨어 기술에 대해서 알아본다. 특별히 IMT-Advanced를 통한 4세대 이동통신의 상용화가 몇 년 앞으로 다가와 있으며, Apple Phone/iPad의 확산에 따른 모바일 기기와 서비스에 대한 급격한 관심과 사용의 증가를 고려하여, 모바일 클라우드 컴퓨팅 환경을 고려한 기술에 대하여 알아본다.