• Asian Pacific Journal of Cancer Prevention
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• v.17 no.5
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• pp.2629-2635
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• 2016

Genetic polymorphisms constitute one of the reasons behind the racial variation in prostate cancer occurrence. Published studies regarding genetic associations of glutathione S-transferase mu 1 (GSTM1) and glutathione S-transferase theta 1 (GSTT1) null deletion polymorphisms with prostatic carcinoma have generated inconsistent results among different populations. To date, even a single meta-analysis is not available representing the association of these genes with prostate cancer in different ethnic groups. Therefore, the aim of the current study was to provide a clear picture of GSTM1 and GSTT1 null deletion and risk of prostate cancer among different ethnic groups (i.e. Asians, Europeans, Americans, Africans and Eurasians). A systematic search was performed with the help of various search engines to find out the all the recent studies (2004 to 2015) evaluating the role of GSTM1 and GSTT1 deletion in prostate cancer development. Odds ratios (ORs) with 95% confidence interval (CI) of a total of 34 studies with 7,281 cases and 9,082 controls was analyzed using STATA and MedCalc software. Overall, GSTM1 deletion (OR 3.67; CI 1.39-9.85; P= 0.001) was strongly associated with prostatic cancer. In the sub group analysis GSTM1 null deletion was also significantly associated with prostate cancer among Asians (OR 4.84; CI 1.08-21.5; P= 0.03), Eurasians (OR 17.69; CI 9.87-31.70; P< 0.001) and Americans (OR 0.11; CI 0.01-1.06; P= 0.05). No association was observed among Europeans (P=0.42) and Africans (P= 0.40). As a whole GSTT1 null deletion (OR 0.85; CI 0.28-2.58; P= 0.77) did not show anyt significant association with prostate cancer risk among different populations. When the data were stratified into different groups, however, Africans demonstrated a significant association of GSTT1 null deletion (OR 1.95; CI 1.57-2.39; P<0.001) with prostate cancer, whereas no association was found among Asians (P= 0.90), Americans (P= 0.50), Europeans (P= 0.89) and Eurasians (P= 1.0). In conclusion, both GSTM1 and GSTT1 may contribute to prostate cancer development but GSTM1 may prove to be a stronger candidate risk factor.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.38 no.2
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• pp.117-128
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• 2001

In order to achieve optimal retrieval, i.e., to find the best match to a query according to a certain similarity measure, the exhaustive search should be performed literally for all the images in a database. However, the straightforward exhaustive search algorithm is computationally expensive in large image databases. To reduce its heavy computational cost, this paper presents a fast exhaustive multi-resolution search algorithm based on image database clustering. Firstly, the proposed algorithm partitions the whole image data set into a pre-defined number of clusters having similar feature contents. Next, for a given query, it checks the lower bound of distances in each cluster, eliminating disqualified clusters. Then, it only examines the candidates in the remaining clusters. To alleviate unnecessary feature matching operations in the search procedure, the distance inequality property is employed based on a multi-resolution data structure. The proposed algorithm realizes a fast exhaustive multi-resolution search for either the best match or multiple best matches to the query. Using luminance histograms as a feature, we prove that the proposed algorithm guarantees optimal retrieval with high searching speed.

• Korean Journal of Veterinary Research
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• v.32 no.3
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• pp.435-450
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• 1992

To evaluate the fertilizing capacity of domestic animal spermatozoa by hamster test, semen were collected from 15 boars(Duroc, Landrace, and Yorkshire) and 2 mixed dogs which had been proved to be fertile in the past then, the semen were preserved in BWW medium at $4^{\circ}C$ or $18^{\circ}C$ for about 20 hours and coincubated with zona-free hamster ova for 5 hours. The ova were stained by lacmoid and examined under phase contrast microscope to investigate the rates of sperm binding to the ova, penetration and formation of a male pronucleus, and the numbers of both bound and penetrated sperm per ovum. Both the semen preserved at $18^{\circ}C$ for about 20 hours and that treated by swim up procedure showed considerably higher rates of sperm binding and penetration as well as higher number of penetrated sperm than that preserved at $4^{\circ}C$ for about 20 hours, respectively(p<0.01). Motility of boar sperm at insemination was from 40 to 90% and no difference in hamster test was obtained according to different degree of sperm motility. Abnormality in morphology of boar sperm at insemination was from 6 to 45% and no difference in hamster test was obtained according to different degree of sperm abnormality. The sperm concentrations of $7{\times}10^7$ and $7{\times}10^6$ showed considerably higher rates of sperm binding and penetration as well as higher number of bound sperm than that of $7{\times}10^4$ (p<0.01) along with the same higher results than that of $7{\times}10^5$(0<0.05), respectively. Boar sperm showed considerably higher rates of sperm binding and penetration as well as higher numbers of both bound and penetrated sperm than dog sperm, when both semen were treated by BWW＋heparin medium and swim up procedure, respectively. These results indicated that fertile boar sperm showed considerably lower rates in the results of hamster test, when preserved at $4^{\circ}C$ for about 20 hours and in lower concentration of sperm than when preserved at $18^{\circ}C$ for about 20 hours and in higher concentration of sperm, respectively, and at the same time considerably higher results than fertile dog sperm, consequently to prove that hamster test would be of great value in assaying the fertilizing capacity of boar sperm.

• Journal of the Korean Institute of Gas
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• v.1 no.1
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• pp.27-32
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• 1997

Continual monitoring of abnormal operating conditions i a key issue in maintaining high product quality and safe operation, since the undetected process abnormality may lead to the undesirable operations, finally producing low quality products, or breakdown of equipment. The statistical projection method recently highlighted has the advantage of easily building reference model with the historical measurement data in the statistically in-control state and not requiring any detailed mathematical model or knowledge-base of process. As the complexity of process increases, however, we have more measurement variables and recycle streams. This situation may not only result in the frequent occurrence of process Perturbation, but make it difficult to pinpoint trouble-making causes or at most assignable source unit due to the confusing candidates. Consequently, an ad hoc skill to monitor and diagnose in plat-wide scale is needed. In this paper, we propose a hierarchical plant-wide monitoring methodology based on hierarchical decomposition and principal component analysis for handling the complexity and interactions among process units. This have the effect of preventing special events in a specific sub-block from propagating to other sub-blocks or at least delaying the transfer of undesired state, and so make it possible to quickly detect and diagnose the process malfunctions. To prove the performance of the proposed methodology, we simulate the Tennessee Eastman benchmark process which is operated continuously with 41 measurement variables of five major units. Simulation results have shown that the proposed methodology offers a fast and reliable monitoring and diagnosis for a large scale chemical plant.

• The Journal of the Korea Contents Association
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• v.18 no.3
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• pp.70-80
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• 2018

Due to the recent development of social media and mobile devices, graph data have been using in various fields. In addition, caching techniques for reducing I/O costs in the process of large capacity graph data have been studied. In this paper, we propose a multi-layer caching scheme considering the connectivity of the graph, which is the characteristics of the graph topology, and the history of the past subgraph usage. The proposed scheme divides a cache into Used Data Cache and Prefetched Cache. The Used Data Cache maintains data by weights according to the frequently used sub-graph patterns. The Prefetched Cache maintains the neighbor data of the recently used data that are not used. In order to extract the graph patterns, their past history information is used. Since the frequently used sub-graphs have high probabilities to be reused, they are cached. It uses a strategy to replace new data with less likely data to be used if the memory is full. Through the performance evaluation, we prove that the proposed caching scheme is superior to the existing cache management scheme.

• The Korean Journal of Applied Statistics
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• v.23 no.3
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• pp.443-456
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• 2010

This study is an empirical research of the stock markets to prove the synchronization phenomenon of the world economy. For this research I analyzed Korea's KOSPI, USA's DOW & NASDAQ reflecting stock markets in North America, Japan's NIKKEI in Asia, and Germany's DAX in Europe. Because the raw series are not stationary, they are to be transformed to returns series. The results of the study are follows: First of all, there are significant causalities between KOSPI's returns and those of other indices. Second, feedback effects are found between the market returns with several time lags. Third, there are 4 cointegrating equations which embody the relation of the five returns series. And forth, KOSPI reacts more sensitively to impacts from the foreign indices compared to the other indices do when they got impacts from each other except KOSPI. On conclusion, there exists a clear evidence for the synchronization phenomenon in returns of the stock indices, and we can expect Korea market may get similar changes depending on the economic changes of North America, Europe, or Asia. Therefore more closing researches should be conducted about the world economy synchronization in various fields as soon as possible.

• Physical Therapy Korea
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• v.10 no.2
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• pp.45-59
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• 2003

The purpose of this study was to assess the effects of ultrasound on adjuvant-induced arthritis in rats. Adjuvant arthritis was induced in 26 female Sprauge-Dawley rats by the subcutaneous injection of a single dose of .1 mL of Complete Freund's Adjuvant (CFA) (1 mg of Mycobacterium Butyricum suspended in .1 $m{\ell}$ paraffin oil) into the right hind paw. After confirming inflammatory edema and arthritis in the paw 2 weeks later, the arthritic rats were divided into 3 groups, i.e., a control group, a pulsed ultrasound group (Group A), and a continuous ultrasound group (Group B) with 8 rats placed in each group. The rats in Group A were treated with pulsed ultrasound at 1 MHz frequency with .5 $W/cm^2$ intensity in 1 : 4 mode for 3 minutes. The rats in Group B were treated with continuous ultrasound at 1 MHz frequency with 2 $W/cm^2$ intensity in the continuous mode for 3 minutes. The ultrasound treatment was done in the left and right ankles for 2 weeks. Clinical, radiographic and histopathologic findings were then evaluated before and after treatment and yielded the following results. 1. No significant difference was present in body weight between the control group and the treated groups. 2. A statistically significant decrease in the edema of the paw was seen in the rats in Group A that was treated with pulsed ultrasound by 26~29 days after the treatment started (p<.05). 3. According to radiological examination, Group A showed the lowest score in arthritis scale which means it showed a tendency to suppress arthritic inflammation of the left and right hind paws. However, no statistically significant difference was present in the score between the control group, Group A and Group B. 4. According to histopathologic findings, the degree of infiltration by inflammatory cells and hypertrophy of the synovium were less in Group A compared with the control group and Group B. The results of the study show that rats that were treated with the pulsed ultrasound effectively suppressed adjuvant arthritis. However, more effort is needed to objectively prove the effectiveness of ultrasound by developing more sensitive testing methods that could quantitatively evaluate the treatment effects of acute rheumatoid arthritis and by trying out different ultrasound treatment methods.

• Journal of the Korean Society of Costume
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• v.38
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• pp.193-211
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• 1998

Without a solid marketing system in placed, the fashion industry cannot flourish on out-standing design or technology alone. Even though the significance of collecting and analyzing information, merchandising, and retail distribution is recognized, these functions are not firmly rooted or prevalent in our industry. In contrast, Italy which possesses similar demographic traits such as the lack of natural resources and other physical factors has succeed-ed in globalizing its fashion market by responding swiftly and exercising flexiblity to its constantly changing consumer demand. This in turn has earned Italy the competitive edge in the global fashion arena. Italy's unique management skills and operation know-how, along with successful market strategies come into play in bringing competitiveness to Italy's fashion market. Firstly, smaller companies with ability to adopt swiftly to the ever changing market. Secondly, fashion friendly social environment. Thirdly, niche marketing through highly specialized system and differentiation. Fourthly, timeless innovation through intense corporate competition. Lastly, establishment of foundations to support the industry through diverse networking. The alone building blocks have formed a basis for erecting an unparalleled market with a reputation for excellence in design and quality in the global fashion world. This study has examined how Italy's fashion industry has evolved from an underdeveloped textile business into a cutting edge fashion in-dustry. Italy's unique business processes and practices were studied to come up with a collection and merchandising ideas in a niche market. By selecting this venue we are able to continuously grow and develop in a market with diverse consumer needs. To analyze the Italian fashion market, data from 3 institutions were utilized, namely, CIT-ER which has provided consumer trends and sales analysis, SITA,a data service provided statistics from the textile and apparel businesses, and NBI has also furnished valuable data. Italian consumer preference, buying behavior, consumer profile, retail channels and other related data from the above institutions has formed a backbone for market segmentation and target markets, and as a result, we were able to zero in on the type of consumer, produce, pricing and retail channels for our womenswear. Going forward the direction is to elevate product image and pretige, and create syn-ergy between related industries, and at the same note, in order to develop internationally recognized brands such as Max Mara and Benetton. Certain elements such as the specialization of the fashion industry, alon-g with fashion-related data base and systems support, and most importantly experts with acute fashion sense and capacity to analyze pertinent data are in need. I firmly believe that we can achieve Italy's level in the fashion market with support from the government and unrelenting effort within the industry itself, and hope that this report can prove to be useful.

• Journal of the Institute of Electronics Engineers of Korea TE
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• v.42 no.1
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• pp.13-20
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• 2005

In this paper, I recognized Korean isolated words using CVEM which is suggested by M. Bilginer et al. CVEM is an algorithm which is easy to extract the common properties from training voice signals and also doesn't need complex calculation. In addition CVEM shows high accuracy in recognition results. But, CVEM has couple of problems which are impossible to use for many training voices and no discriminant information among extracted common vectors. To get the optimal common vectors from certain voice classes, various voices should be used for training. But CVEM is impossible to get continuous high accuracy in recognition because CVEM has a limitation to use many training voices and the absence of discriminant information among common vectors can be the source of critical errors. To solve above problems and improve recognition rate, k-clustering subspace method and DCVEM suggested. And did various experiments using voice signal database made by ETRI to prove the validity of suggested methods. The result of experiments shows improvements in performance. And with proposed methods, all the CVEM problems can be solved with out calculation problem.

• Journal of the Korean Society of Food Science and Nutrition
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• v.42 no.8
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• pp.1190-1196
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• 2013

The purpose of this study was to investigate the mechanism and effects of different types of ginseng on memory improvement in an experimental rat model. In this study, SD rats were induced for memory deficits through scopolamine treatment (1 mg/kg, i.p.) then administrated with ginseng extract for 7 weeks. The rats were divided into five groups: saline (1 mL/kg, NC: negative control), white ginseng (300 mg/kg, WG), red ginseng (300 mg/kg, RG), black ginseng (300 mg/kg, BG), and scopolamine (1 mg/kg, PC: positive control). The step through latency of the BG and RG groups was significantly longer than the PC group in the retention trial of multiple trial passive avoidance test. In the spatial reference memory triads of the Morris water maze test, the latency time of BG and RG was significantly lower than the PC group. In addition, in the prove test, the time spent in the platform quadrant of BG and RG groups were significantly longer than the PC group. Brain choline acetyltransferase (ChAT) activities BG and RG groups significantly increased compared to other groups. On the other hand, the levels of malondialdehyde (MDA) were significantly lower in the BG and RG groups compared to other groups. These result suggested that black ginseng could be useful to enhance learning memory and cognitive function by regulation of cholinergic enzymes.