• Korean Journal of Occupational Health Nursing
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• v.11 no.2
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• pp.158-163
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• 2002

This study aimed to develop hypertension control programs and to analyse their effects in small scale enterprises. The program was self-efficacy promoting program for worker with hypertension. The target population of the programs are 67 workers. The program was conducted for 18 weeks after a pre- intervention survey. Data were analyzed by the SAS program with paired t-test. The results of the study are as follows; First, after the program, scores on self-efficacy were increased significantly. Second, after the program, life-style change was increased significantly. Third, the blood pressure level was diminished in the program. The workers have lost systolic blood pressure by 18mmHg and diastolic blood pressure by 13mmHg. In conclusion, the self-efficacy promoting program is an effective intervention to lower the blood pressure. Thus this program can be recommended as an intervention program of hypertension in small scale enterprises.

• Research in Community and Public Health Nursing
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• v.22 no.2
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• pp.100-110
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• 2011

Purpose: The purpose of this study was to evaluate the effects of hand moxa and hand press pellet on blood pressure, blood lipids and blood cell components in elderly women. Methods: This study was conducted as a quasi-experiment with none equivalent control group pre-post test design. The participants were elders who had essential hypertension. There were 18 members in the experimental group and 20 members in the control group. The experimental group received hand moxibustion and hand press pellet 3 times a week for 12 weeks. The results were analyzed using $x^2$ test, t-test, Fisher's exact test and repeated measures ANOVA with the SPSS/WIN program. Results: There were significant decreases in blood pressure in the experimental group compared to the control group. No significant difference was observed in total triglyceride, LDL cholesterol and HDL cholesterol between the two groups. Differences in hemoglobin and hematocrit were not significant either. However, there were significant increases in RBC in the experimental group after the intervention. Conclusion: The results suggest that combined hand therapy contributes to the decrease of blood pressure among the elderly with hypertension. Therefore combined hand therapy is recommended as a complementary nursing intervention strategy for the elderly with essential hypertension.

• Toxicological Research
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• v.22 no.2
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• pp.69-74
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• 2006

Hypertension leads to major health problems in many industrialized countries, and multiple etiologic factors are involved in the pathogenesis of this disorder. The genetic components of the natriuretic peptide system might be involved in the pathogenesis of hypertension. In this regard, the atrial natriuretic peptide (ANP) gene has been proposed as a candidate hypertension gene. Therefore, we investigated the G1837A and C-664G polymorphisms of the ANP gene in 143 Korean normotensives and 118 hypertensives. There were no significant differences in the genotype and allele frequencies between the two groups. Although the frequencies in each of these polymorph isms were not significantly different between normotensives and hypertensives, our results provide additional ethnic information for linkage analysis and associated studies of this disorder with cardiovascular disease.

• CELLMED
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• v.3 no.2
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• pp.16.1-16.5
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• 2013

Hypertension induces many of the social costs related by cardiovascular diseases. Sodium is known as a crucial factor in inducing type I hypertension. In traditional Korean medicine, bamboo salt (BS) has been used in the attenuation of salts toxic coldness and nowadays it has shown various therapeutic effects. It contains mostly sodium chloride (about 91.7% of BS); however, the effect of BS on hypertension is still not completely understood. Thus, we investigated the effect of BS on blood pressure for the first time. Two group of BS, sun-dried salt (SDS), NaCl, or distilled water (DW, vehicle control) was administrated orally for 8 weeks. Although BS had no effect on body weight and food intake, it increased water intake (p < 0.05). The BS groups, in terms of blood pressure, was similar to the DW group; whereas the SDS and NaCl groups showed significantly increased blood pressure levels (p < 0.05). BS also decreased sodium-chloride cotransporter (NCC) mRNA expression, unlike SDS or NaCl. These observations indicate that BS may be a promising strategy for the prevention of various diseases including salt-related diseases.

• The Korean Journal of Physiology and Pharmacology
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• v.21 no.1
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• pp.99-106
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• 2017

Obesity is a critical risk factor for the hypertension. Although angiotensin II (Ang II) in obese individuals is known to be upregulated in obesity-induced hypertension, direct evidence that explains the underlying mechanism for increased vascular tone and consequent increase in blood pressure (BP) is largely unknown. The purpose of this study is to investigate the novel mechanism underlying Ang II-induced hyper-contractility and hypertension in obese rats. Eight-week old male Sprague-Dawley rats were fed with 60% fat diet or normal diet for 4 months. Body weight, plasma lipid profile, plasma Ang II level, BP, Ang II-induced vascular contraction, and expression of regulatory proteins modulating vascular contraction with/without Ang II stimulation were measured. As a result, high fat diet (HFD) accelerated age-dependent body weight gaining along with increased plasma Ang II concentration. It also increased BP and Ang II-induced aortic contraction. Basal expression of p-CPI-17 and myosin light chain (MLC) kinase was increased by HFD along with increased phosphorylation of MLC. Ang II-induced phosphorylation of CPI-17 and MLC were also higher in HFD group than control group. In conclusion HFD-induced hypertension is through at least in part by increased vascular contractility via increased expression and activation of contractile proteins and subsequent MLC phosphorylation induced by increased Ang II.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.19 no.4
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• pp.474-482
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• 2012

Purpose: The purposes of this study were to identify knowledge, health belief and compliance in patients with hypertension and to identify the most important predictors for compliance of hypertensive patient. Method: The participants in this study were 117 patients who were receiving treatment for hypertension at E. university hospital or one of three local clinics in D-city. Data were collected using a knowledge measurement instrument, health belief scale, and an instrument on compliance. Collected data were analyzed using $X^2$ test, ANOVA, multiple linear regression with PASW statistics 18.0 program. Results: There were statistically significantly positive correlations between knowledge of hypertension and health belief, health belief and compliance. But there was no correlation between knowledge of hypertension and compliance. In the multiple regression analysis, perceived barriers, perceived severity, perceived benefits were significant predictors to explain compliance and accounted for 54.1% of the variance in compliance. Conclusion: The results of the study indicate that health belief and compliance are significantly strongly correlated. Thus it is suggested that nursing interventions to improve compliance should include nursing care plans to increase health belief, perceived severity, perceived benefit and to decrease perceived barrier.

• Korean Journal of Adult Nursing
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• v.19 no.4
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• pp.644-655
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• 2007

Purpose: The purposes of this study were to describe the pattern of type D personality, to compare the life style and quality of life between type D personality and non-type D personality patients, and to investigate the factors influencing quality of life in patients with hypertension. Methods: A cross sectional, descriptive study was used. The participants in this study were 193 outpatients who were diagnosed with hypertension at two university hospitals in urban area, Korea. The data was collected from December, 2006 to January, 2007. Type D personality was measured by the DS-14 scale. Results: The prevalence of type D personality was 83.9%. Patients of type D personality were significantly different in educational status, monthly income, fat intake and exercise, and had a lower overall quality of life than patients of non-type D personality. Under controlled general characteristics and life style factors, multiple linear regression analysis was performed. The most significant factor influencing quality of life in hypertensive patients was type D personality, and this factor explained their quality of life with a variance of 14.8%. Conclusions: Various programs for psychological intervention are required to control for the distressed personality of patients with hypertension. Further studies should be conducted prospectively on a larger patient population.

• Journal of Korean Academy of Nursing
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• v.38 no.4
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• pp.593-602
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• 2008

Purpose: This study aimed to compare self-care behaviors and depressive symptoms between the young old (65-74 yr) and the old-old (75-84 yr) in low-income women with hypertension. Methods: This study used a descriptive research design. The subjects of this study were 136 elderly women over 65 yr living in D city. Data was collected from September to December 2007 through personal interviews using a questionnaire. The collected data was analyzed using the SPSS WIN 12.0 Program. Results: Self-care behaviors, functional status, and number of medications showed a significant difference between young elderly and middle elderly. There was a negative correlation between self-care behaviors and depressive symptoms. 52.2% of variance in self-care behaviors of young elderly and 76.8% of variance in self-care behaviors of middle elderly were explained by depressive symptoms, number of medications, and functional status. Conclusion: It is necessary to manage depressive symptoms to improve the self-care behaviors of low-income elderly with hypertension. Depressive symptoms need to be considered in planning hypertension programs for low-income elderly women.

• Korean Journal of Adult Nursing
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• v.19 no.1
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• pp.109-120
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• 2007

Purpose: This study was conducted to investigate factors related to middle-aged women's health beliefs and their intention to practice health behaviors for preventing and improving hypertension. Methods: The participants were 319 middle-aged(40-59 years) women who lived G city. Data was collected from January to February, 2005. Personal interviews were performed. The data was analyzed using t-test, ANOVA, Scheffe's multiple comparison test and hierarchial multiple regression analysis. Results: Perceived susceptibility of health belief was high in those who had higher educational level, disease history and health education experience, significantly(p<0.05). Perceived seriousness was high in those who had higher educational level, middle economic status and health education experience, significantly(p<0.05). Perceived benefits was high in those who had higher educational level and perceived barriers was low in those who had disease history and hypertension, significantly(p<0.05). The subject's intention to practice health behaviors was significantly high in those who were younger, who had higher educational level and menopausal status(p<0.05). In hierarchial multiple regression analysis, the subject's intention was related to perceived seriousness, perceived benefit and educational level, significantly(p<0.05). Conclusion: It is necessary to develope the education programs which can increase the subject's health belief and intention to practice health behaviors towards hypertension in middle-aged women.

• Korean Journal of Adult Nursing
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• v.19 no.2
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• pp.248-259
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• 2007

Purpose: The purpose of this study was to explore the experiences of young adults with hypertension, using phenomenology in order to describe the essence of such experiences and to understand them from the patients' point of view. Methods: Participants in this study were 4 hypertension patients with ages ranging from 20 to 35 years old, living in Seoul city. Data were collected from in-depth interviews done from October to November in 2005. Colazzi method(1978) was used to analyze the data. Results: The 12 themes were extracted in this study ; 'Discovery by accident', 'Denial of the diagnosis', 'A disease unworthy of the young men', 'Guilty feeling toward their parents', 'Fear of death', 'Unconvinced reason', 'Worry about the future', 'Attribute all symptoms to the disease', 'Will of not life-long medication', 'Concern for fertility problem', 'Not convinced with current treatment method', 'Becoming unimportant'. Conclusion: The results of this study show that the young adult with hypertension will be in a high risk group of non compliance, so helpful program for them should be developed and the nurses need to pay more attention to the psychosocial aspect of nursing.