• 대한약학회:학술대회논문집
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• 대한약학회 2000년도 춘계총회 및 학술대회
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• pp.198.3-199
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• 2000

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.157-158
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• 2003

A newly synthesized thiazolodinedione derivative, CKD-501, was confirmed to have antihyperglycemic effect in in vivo study. The present study was undertaken to investigate the effect of CKD-501 on glucose transport and its stimulating mechanism in L6-myotubes. L6-myoblasts were cultured and differentiated to myotubes by reducing serum concentration in media from 10％ to 2％. (omitted)

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.158.2-159
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• 2003

Cadmium is well known as a toxic metal and has insulin mimicking effects in rat adipose tissue. To investigate the effect of CdCl2 on glucose transport and its mechanism, this study was performed in 3T3-L1 adipocytes. 10 and 25mM of CdCl2 exposed to cells for 12 hours increased 2-deoxyglucose uptake to 2.2 and 2.8 fold, respectively. Nifedipine, a calcium channel blocker, inhibited the 2-deoxyglucose uptake stimulated by CdCl2. (omitted)

• 한국식품조리과학회지
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• 제22권2호
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• pp.229-236
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• 2006

The study investigated the hygienic practice attitudes of 500 housewives living in the Seoul area through survey. The suey questionnaire evaluated general information, purchasing behaviors, 4 parts of hygienic practice attitude and the associated factors. The subjects were mostly full-time housewives aged in their $30{\sim}40's$, high school graduates from middle-class families who had been married for $6{\sim}10$ years. The mean score for hygienic practice attitude was 2.9 out of 5 point scale, representing a fairly low hygienic practice attitude except for food preparation area(3.4 pt.). Factors affecting hygienic practice attitude were age, occupation, and marriage term. Practice attitude was positively correlated with age (p<0.01). Full-time housewives had better practice attitude. Housewives with <5 and >26 years of marriage showed inferior practice attitude (p<0.05). In addition, food purchasing behaviors were strongly related to hygienic practice attitude. Housewives gathering hygiene information from mass media maintained a significantly higher practice attitude (p<0.05), and so did the housewives focusing on 'nutrition' and 'freshness' when fish and frozen foods were purchased (p<0.05). In contrast, housewives focusing on cost had a significantly lower practice attitude (p<0.05). In conclusion, the level of hygienic practice attitude of housewives was fairly low and was affected by age, occupation status, marriage term and several aspects of purchasing behaviors. Therefore, it is extremely important to conduct training and education for housewives to improve their hygienic practice attitude and awareness of hygiene.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.144-145
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• 2003

Hangover is associated with ethanol metabolism in body after the ingestion of an alcoholic beverage. Especially. The metabolism in liver is forcused by many researcher because, alcohol (approximately 90％) is metabolized by the liver. Ethanol metabolism in liver involves both liver alcohol dehydrogenase(ADH) which actalyzes the oxidation of ethanol to acetaldehyde, and liver aldehyde dehydrogenase(ALDH) which metabilized rapidly acetaldehyde, product of ethanol oxidation, to acetate. (omitted)

• Archives of Pharmacal Research
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• 제4권1호
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• pp.63-74
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• 1981

Hygienic Science is the science for the maintenance and the improvement of human health. Every investigation of hygienic science is originated from practical human life and the fruits of every studies should be recovered and utilized finally by social life. The planning, implementation, evaluation must be carried out by unbiased idea in view of four main aspects in Fig. 1. In the center of that figure you can put any problems that you concern if it is related to health sciences. Today. I want to mention the problem in food and environmental contaminants, referring to some recent status of may country.

• 생물환경조절학회지
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• 제30권3호
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• pp.206-211
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• 2021

화분매개곤충으로 중요한 산업적 가치를 지닌 꿀벌은 전 세계적으로 병해충에 의한 개체수 감소 현상이 심각한 문제로 제기 되고 있다. 본 논문에서는 이를 타개하기 위하여 질병저항성 꿀벌 계통을 선발하고자 하였으며, 이를 위해 꿀벌 육성 계통별 청소력(hygienic behavior) 평가를 수행하였다. 이는 질병 저항성 계통 선발에 관한 연구로본 연구에서는 5종의 꿀벌 계통과 2종의 교배종 계통에 대한 청소력 평가를 Pin killed brood assay 법에 의해 수행하였다. 그 결과 처리 24 시간 후 죽은 번데기를 제거하거나 개봉하는 능력이 60% 이상으로 청소능력이 낮은 계통(non-hygienic)은 확인되지 않았으며, 반대로 죽은 번데기를 제거하거나 개봉하는 능력이 90%이상인 hygienic 계통은 C, D, E, F, ♀CX♂D 그리고 ♀FX♂D 계통인 것으로 드러났으며, 그 외A 계통은 보통(intermediate)의 청소능력을 가진 것으로 확인 되었다. 이를 통해 본 연구에서는 육성 계통 대부분이 높은 질병저항성 특성을 지니는 것으로 평가되고 있으며, 이러한 결과는 지속적인 질병저항성 꿀벌 계통 선발에 활용할 수 있을 것으로 기대되고 있다.

• Environmental Analysis Health and Toxicology
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• 제11권3_4호
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• pp.53-57
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• 1996

In this study we investigated the effect of hydroxybrazilin on glutathione depletion induced by BrCCl$_3$ and menadione in cultured hepatocytes to understand the cellular mechanisms of hepatoprotective effect of hydroxybrazilin. Hydroxybrazilin alone had no effect on total glutathione level and the ratio of reduced glutathione/total glutathione (GSH/(GSSG+GSH)). BrCCl$_3$ dramatically decreased total glutathione level and hydroxybrazilin significantly prevented glutathion depletion by BrCCl$_3$. The ratio of GSH/(GSSG+ GSH) was also decreased by BrCCl$_3$ and recovered by hydroxybrazilin treatment. Menadione decreased total glutathione level and the ratio of GSH/(GSSG+GSH) but hydroxybrazilin showed no significant effects on menadione-induced glutathione depletion. These data suggest that hydroxybrazilin might prevent the hepatotoxicity induced by chemicalderived radicals but not the toxicity linked with oxidative stress.

• 한국식품조리과학회지
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• 제23권1호통권97호
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• pp.25-32
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• 2007

The objective of this study was to investigate the effect of the perceived importance of kitchen equipment and facilities on the hygienic performance of cooks in deluxe hotels. Cooks and chefs at 7 different deluxe hotels participated in this study. Out of 490 questionnaires administered, 456 (93.1%) were completed and 419 (91.9%) were analyzed using a statistical package SPSS 12.0. The results were as follows. First, the correlation between sanitary equipment, including HACCP system, in the hotel kitchens and the hygienic management performance confirmed the significant effect of the sanitary equipment on the performance of the cooks and chefs. Second, the sanitary facilities in the hotel kitchens greatly affected the hygienic management performance. The results also demonstrated that the sanitary equipment provided the same contribution to the performance irrespective of the job level, management type and HACCP practice. However, the sanitary facilities greatly affected the management type expecially the chain hotels. The hygienic management performance did not affect the cooking stage (before-cooking and during-cooking), but affected the after-cooking stage according to the management type and the HACCP practice, but not the job level.

• 한국콘텐츠학회논문지
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• 제18권3호
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• pp.421-431
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• 2018

본 연구는 요양보호사를 위한 기저귀위생간호 교육프로그램을 개발하고, 기저귀 위생간호에 관한 지식과 수행능력에 미치는 효과를 파악하기 위함이다. 연구설계는 비동등성 대조군 전후 유사 실험연구이다. 충청남도 Y군의 장기요양기관에 근무하는 요양보호사 중 실험군 25명과 대조군 25명의 총 50명을 대상자로 선정하였다. 수집된 자료는 SPSS Window 22 version을 이용하여 분석하였으며, 기저귀 위생간호 교육프로그램은 총 4회기로 구성되었다. 교육프로그램의 실험 결과, 기저귀 위생간호 지식은 사전점수($M{\pm}SD=4.64{\pm}0.23$)에 비해 사후점수($M{\pm}SD=4.88{\pm}0.23$)가 증가하였으나, 두 군 간에 통계적으로는 유의하지 않았다(t=1.253, p=.216). 기저귀 위생간호 수행능력은 사전점수($M{\pm}SD=1.86{\pm}0.18$)에 비해 사후점수($M{\pm}SD=2.89{\pm}0.15$)가 증가하였고, 두 군 간에 통계적으로 유의한 차이가 있었다(t=12.694, p=.001). 따라서, 개발된 기저귀 위생간호 교육프로그램은 요양보호사의 기저귀 위생간호 실무능력을 향상시키는데 기여할 수 있을 것으로 기대된다.