• Title/Summary/Keyword: human-to-human (H2H)

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Role of Activated Carbon Modified by H3PO4 and K2CO3 From Natural Adsorbent for Removal of Pb (II) From Aqueous Solutions

  • Manoochehri, Mahboobeh;Khorsand, Ameneh;Hashemi, Elham
    • Carbon letters
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    • v.13 no.3
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    • pp.167-172
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    • 2012
  • Most heavy metals are well-known toxic and carcinogenic agents and when discharged into wastewater represent a serious threat to the human population and the fauna and flora of the receiving water bodies. The present study aims to develop a procedure for Pb (II) removal. This procedure is based on using powdered activated carbon, which was prepared from walnut shells that were generated as plant wastes and modified with potassium carbonate and phosphoric acid as chemical agents. The main parameters, such as effect of pH, effect of sorbent dosage, Pb (II) concentrations, and various contact times influence the sorption process. The experimental results were analyzed by using Langmuir, Freundlich, Tempkin, and Dubinin-Radushkevich adsorption models. The kinetic study of Pb (II) on activated carbon from walnut shells was performed based on pseudo- first order and pseudo- second order equations. The data indicate that the adsorption kinetics follow the pseudo- second order rate. The procedure was successfully applied for Pb (II) removal from aqueous solutions.

TAH(Total Artificial Heart) Virtual Surgery Using Multi-Volume Visualizing Technique (다중 체적 가시 기법을 이용한 완전인공심장의 가상 수술)

  • Lee, D.H.;Kim, J.H.;Kim, N.K.;Min, B.G.
    • Proceedings of the KOSOMBE Conference
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    • v.1997 no.11
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    • pp.587-589
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    • 1997
  • The virtual surgical trial of TAH is very important in some points as follows. The chests of patients who is under heart-disease are various types of undefine form. It is hard to say that there exist the standard shape of TAH and the position to surgern. So, the virtual surgery system is very important in realizing TAH surgery of human. We have implemented virtual surgery system of TAH that supporting multi volume fitting trial. We have acquired CT images of patients with DICOM format. Each organ of patients was segmented in 2-dimensional CT images. 3-dimensional objects were made with marching cube algorithm and save as file in VRML format. Virtual fitting trial was performed on Cosmo-World; a VRML editor. The collision points of TAH with other organs were well observed. And the best position and angles were determined and saved or each case. We believed that this virtual surgery will be helpful in TAH surgery and TAH customizing.

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The Development of Popular type Domestic Superconducting MRI Magnet with Middle Magnetic Field Range (중자장급 보급형 국산 초전도 MRI 마그네트 개발)

  • Bae, J.H.;Ko, R.K.;Sim, K.D.;Jin, H.B.;Cho, J.W.;Lee, E.Y.;Kwon, Y.K.;Ryu, K.S.
    • Proceedings of the KIEE Conference
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    • 2001.04a
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    • pp.22-25
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    • 2001
  • The research results on the superconducting magnet for whole body MRI are presented. The magnet consists of main coil with 6 solenoid coils, shielding coil with 2 solenoid coils and 6 sets of cryogenic shim coil. The ferromagnetic shim assembly is installed on the inside wall of the room temperature bore for shimming inhomogeneous field components generated due to manufacturing tolerances, installation misalignments and external ferromagnetic materials near the magnet. Also, the magnet is enclosed with the horizontal type cryostat with 80cm room temperature bore to keep the magnet under the operating temperature. The magnetic field distributions within the imaging volume were measured by the NMR field mapping system. Through the test, the central field of magnet was 1.5 Tesla and the field homogeneity of 9.3 ppm has been obtained on 40cm DSV(the diameter of spherical volume) and using this magnet, comparatively good images for human body, fruits and water phantoms have been achieved.

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Study on Metabolism and Excretion of Carteolol in Human Urine using GC/MS (GC/MS를 이용한 carteolol의 대사 및 배설연구)

  • Min, Hye-Ki;Kim, Myungsoo;Cho, Hyun-Woo;Kim, Taek-Jae;Kim, Dong-Hyun;Myung, Seung-Woon
    • Analytical Science and Technology
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    • v.15 no.5
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    • pp.482-487
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    • 2002
  • International Olympic Committee (IOC) prohibits the use of carteolol which is one of ${\beta}$-blockers. To prove whether carteolol product was taken or not, the analytical method in urine using GC/MS was established, and metabolism and excretion study were evaluated. As compared with acid hydrolysis, enzyme hydrolysis method was more efficiency. Coefficients of variation for intra-assay precision was around 10%. Error was less than 5% except the concentration of $0.05{\mu}g/m{\ell}$. Recovery was 78.5% at $2{\mu}g/m{\ell}$. Free carteolol, conjugated carteolol, and small amount of p-OH carteolol were found in dosed human urine samples. The conjugated form was being 59.4% of the total carteolol in human urine. The amount of carteolol renal excreted for 72 h after oral dose of 10 mg of carteolol was 49% of the administred dose.

Light/Dark Responsiveness of Kinetin-Inducible Secondary Metabolites and Stress Proteins in Rice Leaf

  • Cho, Kyoung-Won;Kim, Dea-Wook;Jung, Young-Ho;Shibato, Junko;Tamogami, Shigeru;Yonekura, Masami;Jwa, Nam-Soo;Kubo, Akihiro;Agrawal, Ganesh Kumar;Rakwal, Randeep
    • Journal of Crop Science and Biotechnology
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    • v.10 no.2
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    • pp.112-116
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    • 2007
  • Kinetin(KN) is an inducer of rice(Oryza sativa L.) defense/stress responses, as evidenced by the induction of inducible secondary metabolite and defense/stress protein markers in leaf. We show a novel light-dependent effect of KN-triggered defense stress responses in rice leaf. Leaf segments treated with KN(100 ${\mu}M$) show hypersensitive-like necrotic lesion formation only under continuous light illumination. Potent accumulation of two phytoalexins, sakuranetin and momilactone A(MoA) by KN that peaks at 48 h after treatment under continuous light is completely suppressed by incubation under continuous dark. Using two-dimensional gel electrophoresis we identified KN-induced changes in ribulose-1, 5-bisphosphate carboxylase/oxygenase, energy- and pathogenesis-related proteins(OsPR class 5 and 10 members) by N-terminal amino acid sequencing and mass spectrometry. These changes were light-inducible and could not be observed in the dark(and control). Present results provide a new dimension(light modulation/regulation) to our finding that KN has a potential role in the rice plant self-defense mechanism.

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C-Glycoside-Metabolizing Human Gut Bacterium, Dorea sp. MRG-IFC3

  • Huynh Thi Ngoc Mi;Santipap Chaiyasarn;Heji Kim;Jaehong Han
    • Journal of Microbiology and Biotechnology
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    • v.33 no.12
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    • pp.1606-1614
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    • 2023
  • Biochemical gut metabolism of dietary bioactive compounds is of great significance in elucidating health-related issues at the molecular level. In this study, a human gut bacterium cleaving C-C glycosidic bond was screened from puerarin conversion to daidzein, and a new, gram-positive C-glycoside-deglycosylating strain, Dorea sp. MRG-IFC3, was isolated from human fecal sample under anaerobic conditions. Though MRG-IFC3 biotransformed isoflavone C-glycoside, it could not metabolize other C-glycosides, such as vitexin, bergenin, and aloin. As evident from the production of the corresponding aglycons from various 7-O-glucosides, MRG-IFC3 strain also showed 7-O-glycoside cleavage activity; however, flavone 3-O-glucoside icariside II was not metabolized. In addition, for mechanism study, C-glycosyl bond cleavage of puerarin by MRG-IFC3 strain was performed in D2O GAM medium. The complete deuterium enrichment on C-8 position of daidzein was confirmed by 1H NMR spectroscopy, and the result clearly proved for the first time that daidzein is produced from puerarin. Two possible reaction intermediates, the quinoids and 8-dehydrodaidzein anion, were proposed for the production of daidzein-8d. These results will provide the basis for the mechanism study of stable C-glycosidic bond cleavage at the molecular level.

Association Between HLA-DQ Genotypes and Haplotypes vs Helicobacter pylori Infection in an Indonesian Population

  • Zhao, Yang;Wang, Jingwen;Tanaka, Tsutomu;Hosono, Akihiro;Ando, Ryosuke;Soeripto, Soeripto;Triningsih, F.X. Ediati;Triono, Tegu;Sumoharjo, Suwignyo;Astuti, E.Y. Wenny;Gunawan, Stephanus;Tokudome, Shinkan
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.4
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    • pp.1247-1251
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    • 2012
  • Background: Helicobacter pylori is an important gastrointestinal pathogen related to the development of not only atrophic gastritis and peptic ulcer, but also gastric cancer. Human leukocyte antigens (HLA) may play particular roles in host immune responses to bacterial antigens. This study aimed to investigate the association between HLA-DQA1 and DQB1 genotypes and haplotypes vs H. pylori infection in an Indonesian population. Methods: We selected 294 healthy participants in Mataram, Lombok Island, Indonesia. H. pylori infection was determined by urea breath test (UBT). We analyzed HLA-DQA1 and DQB1 genotypes by PCR-RFLP and constructed haplotypes of HLA-DQA1 and DQB1 genes. Multiple comparisons were conducted according to the Bonferroni method. Results: The H. pylori infection rate was 11.2% in this Indonesian population. The DQB1*0401 genotype was noted to be associated with a high risk of H. pylori infection, compared with the DQB1*0301 genotype. None of the HLA-DQA1 or DQB1 haplotypes were related to the risk of H. pylori infection. Conclusions: The study suggests that HLADQB1 genes play important roles in H. pylori infection, but there was no statistically significant association between HLA-DQA1 or DQB1 haplotypes and H.pylori infection in our Lombok Indonesian population.

Immobilization of Arsenic in Tailing by Fenton-like reaction (펜톤유사반응을 이용한 광미중에 비소의 불용화)

  • 정익재;최용수
    • Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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    • 2002.04a
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    • pp.127-130
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    • 2002
  • Recently, the contamination with heavy metals in closed mines has been seriously considered since it can disturb human health through the polluted drinking-water and crops. Therefore, the concerns about the remediation of polluted land and treatment technology for hazardous matters have been accelerated. However, any of practical methods for treatment and/or remediation have not been yet suggested. In this research, a novel technology was studied to immobilize arsenic in tailings and soils disturbed by mining. In this technology, Fenton-like reaction were applied to immobilize arsenic in tailings. In the examination of Fenton-like reaction using pure pyrite, $H_2O$$_2$ and arsenic, the concentrations of extracted arsenic and iron were reduced up to 90 and 75%, respectively From the result of SEM-EDS, the Immobilization of arsenic was observed on the surface of pyrite. Thus, it can be said that the coating and/or adsorption prevents the extraction of arsenic.

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Convergent and Discriminant Validity of the Toddler Behavior Assessment Questionnaire in Korean Children (걸음마기 아동 기질척도의 타당도 연구)

  • Park, Seong Yeon;Rubin, Kenneth H.
    • Korean Journal of Child Studies
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    • v.28 no.5
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    • pp.55-72
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    • 2007
  • Replication of the factor structure of the TBAQ(Toddler Behavior Assessment Questionnaire Goldsmith, 1988) in Korean 2-year-old children was examined by Multitrait Multimethod matrix of observed and reported child behavior. Participants included 113 toddlers and their mothers. Three factors comprising 63 items were identified and labeled as easy, difficult and fearful. On the Child Behavior Checklist(Achenbach & Edelbrock, 1983) difficult temperament was positively related to externalizing while fearful temperament was positively related to internalizing problems. Observation of inhibited child behavior in both unfamiliar social and nonsocial situations demonstrated a positive relationship to observed inhibition of fearful temperament. Easy temperament correlated negatively with both social inhibition and internal behavior problems. Results supported construct validity of TBAQ factors for Korean 2-year-old children.

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RESVERATROL APPEARS TO AFFECT IN A DIFFERENT WAY PRIMARY VS. FIXED DNA DAMAGE INDUCED BY $H_2O_2$ IN MAMMALIAN CELLS IN VITRO

  • Salvia, Rosella-De;Fabiola Festa;Ruggero Ricordy;Paolo Perticone;Cristina Mucc;Renata Cozzi
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2001.10a
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    • pp.108-109
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    • 2001
  • Resveratrol (3, 5, 4'-trihydroxystilbene) is a naturally occuring molecule, synthesized by several plants in response to different stresses. Recently many studies performed in human and mammalian cells demonstrated the involment of resveratrol in the modulation of several biological processes (inhibition of lipidic peroxidation, platelet aggregation, estrogenic activity). It has also been found to possess scavenging and antioxidant properties (1).(omitted)

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