• Restorative Dentistry and Endodontics
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• v.24 no.2
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• pp.322-329
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• 1999

The hydrodynamic theory of dentin sensitivity states that movement of tubular contents or tubular fluid, in either direction of dentinal tubule, causes dentin sensitivity. A corollary of that theory is that anything that can decrease dentinal fluid movement or dentin permeability should decrease dentin sensitivity. A wide variety of physicochemical methods have been used to reduce the permeability and sensitivity of exposed dentin. The purpose of this study was to evaluate the ability of 4 kinds of clinical desensitizing agents(2% NaF, 30% Potassium oxalate, MS Coat$^{(R)}$, Tubulitec system$^{(R)}$) to reduce the rate of fluid flow through dentin in vitro. Sixty coronal dentin discs, 1mm in thickness, were prepared from extracted third molars, free from decay and wear. Dentin discs were treated with 3% EDTA(Tubulicid Plus$^{(R)}$(Dental Therapeutics AB, Sweden)) to remove the smear layer and debris occluding the tubular orifices. After placing the discs in a split chamber device, the rate at which physiologic saline solution could filter across dentin under 150cm $H_2O$ hydrostatic pressure was measured. The occlusal side of the discs were then treated with MS Coat$^{(R)}$, 2% NaF, Tubulitec system$^{(R)}$, and 30% Potassium oxalate, and the filter ratio of the saline solution was measured again. The following conclusions were drawn : 1. Hydraulic conductance which was measured after the application of desensitizing agents was decreased in all the groups(p<0.05). 2. % change of hydraulic conductance was compared but no significant difference was found among the four desensitizing agents(p>0.05). 2% NaF, 30% Potassium oxalate, MS Coat$^{(R)}$ and Tubulitec system$^{(R)}$ decreased the permeability of dentin. It is considered that above four agents can be used in treating the hypersensitive teeth.

• KIPS Transactions on Software and Data Engineering
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• v.5 no.2
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• pp.95-106
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• 2016

Biometric data may appear different depending on the person and sasang Medicine has a close relationship with the Department. Biometric data not only mean a human heart rate, a blood pressure, a heart rate, and the past medical history, degree of aging, body mass index, but also is used as a reference measure for determining the state of health of the person. So biometric data should be reproduced for the application purposes, depending on their applications. In previous studies, because the biometric data is changed in real time and applies only to snap shut at the time of the continuity of the current time is excluded. Therefore, in this study in order to solve this problem, we propose a biometric data patton analysis model comprising a continuity of time in the big data environment consisting of biometric data. The proposed model can help determine the choice of needle position carefully when using the electronic acupuncture for care and health promotion.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.23 no.1
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• pp.76-85
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• 2010

In general, anesthetic depth is evaluated by experience of anesthesiologist based on the changes of blood pressure and pulse rate. So it is difficult to guarantee the accuracy in evaluation of anesthetic depth. The efforts to develop the objective index for evaluation of anesthetic depth were continued but there was few progression in this area. Heart rate variability provides much information of autonomic activity of cardiovascular system and almost all anesthetics depress the autonomic activity. Novel monitoring system which can simply and exactly analyze the autonomic activity of cardiovascular system will provide important information for evaluation of anesthetic depth. We investigated the anesthetic depth as following 7 stages. These are pre-anesthesia, induction, skin incision, before extubation, after extubation, Post-anesthesia. In this study, temporal, frequency and chaos analysis method were used to analyze the HRV time series from electrocardiogram signal. There were NN10-NN50, mean, SDNN and RMS parameter in the temporal method. In the frequency method, there are LF and HF and LF/HF ratio, 1/f noise, alphal and alpha2 of DFA analysis parameter. In the chaos analysis, there are CD, entropy and LPE. Chaos analysis method was valuable to estimate the anesthetic depth compared with temporal and frequency method. Because human body was involved the choastic character.

• Journal of Physiology & Pathology in Korean Medicine
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• v.21 no.3
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• pp.626-633
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• 2007

To access the safety and efficacy of Chungyeoldodam-tang(CDT), a traditional herbal medicine prescription, on hypertension we examined various parameters involved in the pathogenesis of hypertension. CDT seems to be safe because CDT at the concentrations lower that 250 ug/ml showed no toxic effects in cultured human fibroblast and no toxic effects on liver function. The production of reactive oxygen species (ROS) were greatly decreased in CDT treated group compared with control, and angiotensin converting enzyme activities were reduced by CDT in a dose dependent manner. There was no differences in weight of hearts between control and CDT treated group. The blood pressure and pulse rate were significantly decreased. CDT greatly reduced the levels of plasma hormones including aldosterone, dopamine, and norepinephrine, but not epinephrine, and serum electrocytes including Na$^+$ and Cl$^-$, but not K$^+$. were also decreased. The levels of uric acid, BUN and creatinine were significantly decreased compared with control. These results suggested that CDT has suppressive effects on various pathologic factors in hypertension, and CDT has potential as a safe and effective therapeutics for hypertension.

• Journal of Nutrition and Health
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• v.50 no.3
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• pp.217-224
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• 2017

Purpose: Although it is well known thatmortality and morbidity due to cardiovascular diseases are higher in salt-sensitive subjects than in salt-resistant subjects, their underlying mechanisms related to obesity remain unclear. Here, we focused on salt-sensitive gene variants unrelated to monogenic obesity that interacted with sodium intake in humans. Methods: This review was written based on the modified $3^rd$ step of Khans' systematic review. Instead of the literature, subject genes were based on candidate genes screened from our preliminary Genome-Wide Association Study (GWAS). Finally, literature related to five genes strongly associated with salt sensitivity were analyzed to elucidate the mechanism of obesity. Results: Salt sensitivity is a measure of how blood pressure responds to salt intake, and people are either salt-sensitive or salt-resistant. Otherwise, dietary sodium restriction may not be beneficial for everyone since salt sensitivity may be associated with inherited susceptibility. According to our previous GWAS studies, 10 candidate genes and 11 single nucleotide polymorphisms (SNPs) associated with salt sensitivity were suggested, including angiotensin converting enzyme (ACE), ${\alpha}$-adducin1 (ADD1), angiotensinogen (AGT), cytochrome P450 family 11-subfamily ${\beta}$-2 ($CYP11{\beta}$-2), epithelial sodium channel (ENaC), G-protein b3 subunit (GNB3), G protein-coupled receptor kinases type 4 (GRK4 A142V, GRK4 A486V), $11{\beta}$-hydroxysteroid dehydrogenase type-2 (HSD $11{\beta}$-2), neural precursor cell-expressed developmentally down regulated 4 like (NEDD4L),and solute carrier family 12(sodium/chloride transporters)-member 3 (SLC 12A3). We found that polymorphisms of salt-sensitive genes such as ACE, $CYP11{\beta}$-2, GRK4, SLC12A3, and GNB3 may be positively associated with human obesity. Conclusion: Despite gender, ethnic, and age differences in genetics studies, hypertensive obese children and adults who are carriers of specific salt-sensitive genes are recommended to reduce their sodium intake. We believe that our findings can contribute to the prevention of early-onset of chronic diseases in obese children by facilitating personalized diet-management of obesity from childhood to adulthood.

• Journal of the Korean Institute of Intelligent Systems
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• v.21 no.3
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• pp.353-358
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• 2011

This paper presents a virtual-legged walking model for bipedal robots and analyzes its fundamental RPY(Roll, Pitch, and Yaw) motion effects by simulation. For the purpose of identifying the motion effects of the bipedal walking, we assign some arbitrary trajectories both at the center of mass and at the center of pressure of the robot based on human walking. And then we verify the major moments to the roll, pitch, and yaw directions of the robot. As a result, it is shown that those motions are natural in the process of bipedal walking and they are deeply dependent on the step distance, the vertical level of the center of mass, and the acceleration of the robot. The importance of trajectory planning for the footstep location during a bipedal walking is finally addressed in terms of balance.

• Journal of The Geomorphological Association of Korea
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• v.24 no.3
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• pp.149-159
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• 2017

Coastal dunes have many environmental and ecological socio-economic importances; various human activities, however, have impaired their structures and functions over the years. In 2016, environmental survey on coastal sand dune was carried out to report the present status and update the coastal sand dune list in 2001. This research analyzed the survey data in terms of geomorphological and socio-economic aspects. A list of the 189 coastal sand dune and information was updated by province. A 36.5% reduction in coastal sand dune area have been identified for using agricultural land, development area since the approximately 1940-50s. Development area in coastal sand dune covered small area as 5%, the use intensity was relatively hard. Furthermore, the difference by province also showed. Approximately 80% of the development area was concentrated in 20% of total sand dune several sand dune. It is generally accepted that coastal sand dunes were exposed high development pressure. However the result means that the general brief dose not apply for all sand dune. Therefore, characteristics of each sand dune should be analyzed and concerned the diverse management plans.

• Elastomers and Composites
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• v.38 no.3
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• pp.195-205
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• 2003

This paper presents an analytic method and a design technique for golf shoes with air-cycled pump in the midsole. The golf shoes are modeled using the finite element method for better design by considering the configuration of the midsole and the outsole, which compose the golf shoes. Also the optimum size and shape of air-cycled pump in the midsole is examined. The values or standard human pressure for boundary conditions are adopted for the FEA(Finite Element Analysis). The unknown constants of the strain energy function of Ogden type are observed in accordance with the axial tension test. By the commercial FEM software for nonlinear analysis, MARC V7.3, the strains and the values of volume change for the midsole and the outsole are obtained, respectively. It can be concluded that results obtained by FEM in the midsole and the outsole are different depending on the characteristic of elastomer The results reported herein provide better understanding of analyzing the golf shoes. Moreover, it is believed that those properties of the results can be utilized in the shoes industry to develop the effective design method.

• Journal of the Korea Society of Computer and Information
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• v.15 no.9
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• pp.129-136
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• 2010

With mobile computing, wireless sensor network and sensor technologies, ubiquitous computing services are being realized and could satisfy the feasibility of ubiquitous healthcare to everyone. This u-Healthcare service can improve life quality of human since medical service can be provided to anyone, anytime, and anywhere. To confirm the vision of u-Healthcare service, we've implemented a healthcare system for heart disease patient which is composed of two components. Front-end collects various signals such as temperature, blood pressure, SpO2, and electrocardiogram, etc. As a backend, medical information server accumulates sensing data and performs back-end processing. To simply transfer these sensing values to a medical team may be too trivial. So, we've designed a model based on context awareness for more improved medical service which is based on artificial neural network. Through rigid experiments, we could confirm that the proposed system can provide improved medical service.

• Journal of the Korean Institute of Gas
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• v.25 no.4
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• pp.1-9
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• 2021

The process and facilities of modern chemical plants are becoming increasingly complex, there is possibility of potential risk. Internal chemicals generate stress concentration when operated due to turbulence, laminar flow, pressure, temperature, friction, etc. It causes cumulative fatigue damage, which can damage or rupture chemical facilities and devices. The statistics of chemical accidents found that the highest rate of occurrence was in summer, and in the last five years statistics on chemical accidents, leakage incidents make up a decent percentage of accidents. Chemical leaks can cause serious human damage and economic damage, including explosions and environmental pollution. In this study, based on the leak accident of chemical plant, the risk analysis, and damage effects assessment were estimated using a 3D scanner and FLACS. As a result, if chemicals leak in summer, the risk is higher than in other seasons, the seasonal safety management measures, and countermeasure were estimated.