• Journal of the Korean Society of Physical Medicine
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• v.18 no.2
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• pp.23-31
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• 2023

PURPOSE: This study examined the anthropometric and clinical risk factors and the prevalence of sarcopenia in women aged 40 to 49 years. METHODS: The study design is a cross-sectional research and a total of 2,055 participants were included. The participants were divided into two groups based on their skeletal muscle mass index score. One hundred and twenty-six individuals were assigned to a sarcopenia group, and 1,939 were assigned to a normal group. The following variables were analyzed: age, height, weight, body mass index, waist circumference, skeletal muscle mass index anthropometric measure, systolic blood pressure, diastolic blood pressure, blood laboratory tests, fasting glucose, triglyceride, total cholesterol, and smoking and drinking smoking statuses. RESULTS: The prevalence of sarcopenia was 6.5% (95% CI: 5.33-7.92). Anthropometric variables, such as height, BMI, and waist circumference, showed significance differences between the two groups (p < .05), except for weight variable (p > .05). In terms of blood pressure and blood lab tests, the systolic blood pressure, diastolic blood pressure, fasting glucose, triglyceride, and total cholesterol were all significant risk factors for sarcopenia in the two groups. (p < .05). CONCLUSION: This study identified risk factors and the prevalence of sarcopenia among community-dwelling middle-aged women.

• Journal of Sensor Science and Technology
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• v.32 no.6
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• pp.340-351
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• 2023

Wearable sensors designed for strain, pressure, and temperature measurements are essential for monitoring human movements, health status, physiological data, and responses to external stimuli. Notably, recent research has led to the development of high-performance wearable sensors using innovative materials and device structures that exhibit ultra-high sensitivity compared with their commercial counterparts. However, the quest for accurate sensing has identified a critical challenge. Specifically, the mechanical flexibility of the substrates in wearable sensors can introduce interference signals, particularly when subjected to varying external stimuli and environmental conditions, potentially resulting in signal crosstalk and compromised data fidelity. Consequently, the pursuit of non-interference sensing technology is pivotal for enabling independent measurements of concurrent input signals related to strain, pressure, and temperature, ensuring precise signal acquisition. In this comprehensive review, we present an overview of the recent advances in noninterference sensing strategies. We explore various fabrication methods for sensing strain, pressure, and temperature, emphasizing the use of hybrid composite materials with distinct mechanical properties. This review contributes to the understanding of critical developments in wearable sensor technology that are vital for their ongoing application and evolution in numerous fields.

• Journal of Sensor Science and Technology
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• v.25 no.4
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• pp.235-242
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• 2016

A system for measuring the electrodermal activity (EDA) signal occurring at the sweat glands in the left palm and left finger of the human body was implemented in this study. The EDA measurement system (EDAMS) consisted of an algometer, a biopotential measurement system (BPMS), and a PC. Two experiments were performed to evaluate the function and clinical applicability of EDAMS. First, an experiment was carried out on the linearity of the voltage and the pressure that comprised the output signals of the algometer used for applying a pressure stimulus. Second, the amplitude of the EDA signal acquired from the electrode attached to the left palm or finger was measured while increasing the pressure stimulus of the algometer. When the pressure stimulus of the algometer applied to the left scapula was increased, the amplitude of the EDA signal increased. The amplitude of the EDA signal at the left palm was observed to be greater than that at the left finger. The amplitude of the EDA signal was observed to increase in a relatively linear relation with the intensity of the pressure stimuli. In addition, the latency of the EDA signal acquired from the electrode attached to the left palm or finger was measured while increasing the pressure stimulus of the algometer. When the pressure stimulus of the algometer applied to the left scapula was increased, the latency of the EDA signal decreased. The latency of the EDA signal at the palm was observed to be less than that at the finger. The latency of the EDA signal was observed to decrease nonlinearly with the pressure stimuli.

• Journal of the Korean Society for Precision Engineering
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• v.28 no.1
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• pp.115-122
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• 2011

Recently, we have proposed a hypothesis that spinal structures have a stress sensor driving feedback mechanism, In the human spine, spinal structure could react to modify muscular action in such a way so as to equalize stress at the disc, therefore reduce the risk of injury, In this analysis, abdominal muscle and abdominal pressure, which were not included in the previous study, were added to identify those effects in spine stability during upright stance posture for the case where the intervertebral disc plays the role of mechanoreceptor, The musculoskeletal FE model was consisted with detailed whole lumbar spine, pelvis, sacrum, coccyx and simplified trunk model. Muscle architecture with 46 local muscles containing paraspinal muscle and 6 rectus abdominal muscles were assigned according to the acting directions. The magnitude of 4kPa was considered for abdominal pressure. Minimization of the nucleus pressure deviation and annulus fiber average tension stress deviation was chosen for cost function. Developed model provide nice coincidence with in-vivo measurement (nucleus pressure). Analysis was conducted according to existence of co-activation of abdominal muscle and abdominal pressure. Antagonistic activity of abdominal muscle produced stability of spinal column with relatively small amount of total muscle force. In contrast to the abdominal muscle, effect of abdominal pressure was not clear that was partly depending on the assumption of constant abdominal pressure.

• Korean Journal of Medicinal Crop Science
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• v.19 no.2
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• pp.103-110
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• 2011

This study was performed to enhance anticancer activities of Lithospermum erythrorhizon by eluting high amount of shikonin through ultra high pressure process. Extraction yield was increased up to 5~10% by ultra high pressure process, compare to the normal extraction processes such as water solvent extraction, 70% ethyl alcohol solvent extraction. The cytotoxicity of the extracts ($1.0{\mu}g/m{\ell}$) from ultra high pressure process was showed the lowest cytotoxicity 13.4% for human lung cell (HEL299). The anticancer activities showed 80~85% by adding $1.0{\mu}g/m{\ell}$ of the extracts from ultra high pressure process in several cancer cell lines such as AGS, Hep3B, MCF-7 and HeLa cells. Among them, MCF-7 cell of the endocrine system was highest inhibited than other cells. The anticancer activities of the extracts from ultra high pressure extraction process showed 10~15%, which was higher than the extracts from normal extraction processes. From HPLC analysis of the extracts, the contents of shikonin in the extracts from ultra high pressure process was 11.42% (w/w), which was 20% higher than others. This results indicate that ultra high pressure process could increase the extraction yield of shikonin and other contents, which resulted in higher anticancer activities.

• The Transactions of the Korean Institute of Electrical Engineers P
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• v.59 no.1
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• pp.58-63
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• 2010

In this paper, we proposed a wearable respiration measurement system with textile capacitive pressure sensor. Belt typed textile capacitive pressure sensor approach of respiration measurement, from which respiration signatures and rates can be derived in real-time for long-term monitoring, are presented. Belt typed textile capacitive pressure sensor has been developed for this measurement system. the distance change of two plates by the pressure of motion has been used for the respiration measurement in chest area. Respiration rates measured with the textile capacitive pressure sensor was compared with standard techniques on 8 human subjects. Accurate measurement of respiration rate with developed sensor system is shown. The data from the method comparison study is used to confirm theoretical estimates of change in capacitance by the distance change. The current version of respiratory rate detection system using textile capacitive pressure sensor can successfully measure respiration rate. It showed upper limit agreement of $3.7997{\times}10^{-7}$ RPM, and lower limit of agreement of $-3.8428{\times}10^{-7}$ RPM in Bland-Altman plot. From all subject, high correlation were shown(p<0.0001). The proposed measurement method could be used to monitor unconscious persons, avoiding the need to apply electrodes to the directly skin or other sensors in the correct position and to wire the subject to the monitor. Monitoring respiration using textile capacitive pressure sensor offers a promising possibility of convenient measurement of respiration rates. Especially, this technology offers a potentially inexpensive implementation that could extend applications to consumer home-healthcare and mobile-healthcare products. Further advances in the sensor design, system design and signal processing can increase the range and quality of the rate-finding, broadening the potential application areas of this technology.

• Journal of the Korean Society of Clothing and Textiles
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• v.45 no.4
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• pp.586-597
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• 2021

This study analyzed clothing pressure, blood flow, and subjective sensations among women in their 50s and 60s while wearing commercially available yoga bra tops (YBTs). These findings could then serve as basic data for designing YBT for women in this age range. Clothing pressure and blood flow reactions were measured in seven participants wearing four commercially available YBTs. Subjective sensations of pressure and comfort were also evaluated. The calculated data were analyzed using the SPSS 24.0 statistical program. The results suggested that YBT4 exerted the lowest clothing pressure, while YBT2 and YBT3 exerted relatively higher clothing pressures. Participants' blood flow decreased while wearing YBTs compared to the control garment. The decrease of 47.3% when the participants wore YBT2 was especially significant. The results confirmed that the blood velocity rate was physiologically lower while wearing all four YBTs than when wearing the control garment. Results for subjective pressure and overall comfort confirmed that YBT2 and YBT3 exerted relatively high pressure, while YBT4 did not exert pressure.

• Fashion & Textile Research Journal
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• v.21 no.1
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• pp.67-74
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• 2019

This study aims to investigate the relation between pressure, 3D length change, and subjective pressure sensation in sports brassieres. Seven Korean women in their 20s and 30s were chosen as subjects. In the experiment, the subjects evaluated four types of sports brassieres wherein the lower band was changed. The results of the study were as follows. The pressure according to the measurement position was lower at the front part than at the side and back parts (p<.05), and there was no difference in the pressure according to the brassiere type. It was observed that brassiere C, which had the higher extension band, was elongated more than the other brassieres when worn. In the case of brassiere B, which had a slit in the front center, it was observed that the 3D length of the front part changed very little as the slit spreads, and the back part stretched in a manner similar to those of the other brassieres. Subjective pressure sensation was statistically different only at the front and the side of the lower band. Brassiere B(with a silt) demonstrated the least subjective pressure sensation; the pressure sensation was high when wearing brassieres A and D (p<.05). Brassieres B and C were also preferred for overall comfort. In conclusion, it was observed that the substitution of material and morphological transformation affect subjective sensation.

• 한국생물공학회:학술대회논문집
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• 2001.11a
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• pp.221-224
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• 2001

Effect of hyperosmotic pressure on growth of recombinant Chinese hamster 。 vary cells and Erythropoietin (EPO) production was investigated. Cells were cultivated in batch modes at various osmolalities. When the osmolality increased from 314 to 463mOsm/Kg, specific EPO productivity (qp) was increased up to 1.6-fold but cell growth was inhibited. EPO has a complex oligosaccharide structure that plays an important role in biological activity in vivo. To investigate the influence of hypoerosmotic pressure on the glycosylation, structural analysis of oligosaccharide was calTied out. Recombinant human EPO was produced by CHO cells grown under various osmotic pressure and purified from culture supernatants by heparin-sepharose affinity column and immunoaffinity column. N-linked oligosaccharides were released enzymatically and isolated by paper chromatography. The isolated oligosaccharides were labeled with fluorescent dye, 2-aminobenzamide and analyzed with MonoQ anion exchange chromatography and GlycosepN amide chromatography for the assignment of GU (glucose unit) value. Glycan analysis by HPLC showed that neutral (asialo) oligosaccharide was increased slightly with an increase in osmolality. In portion of sialylated glycan, total relative amount of mono- and di-sialyated glycan was increased but that of tri- and tetra-sialylated glycan decreased as osmolality was increased.

• Tribology and Lubricants
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• v.15 no.3
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• pp.272-277
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• 1999

The objective of this investigation is to examine the influence of the micro catheters, which mimic the intravascular micro active endoscopes, on local pressure changes and flow rate in an arterial branch model similar to the femoral artery of human. The effects of branch to main lumen flow rate ratios and the locations of a catheter tip were found to be significant on the local pressure changes. Relatively large pressure drops and an increase in shear stress due to the obstruction effects may induce an endothelial cell damage and a change in arterial wall permeability, which have been reported to be the primary cause of the initiation of the atherosclerosis and other major vascular diseases.