• Asian-Australasian Journal of Animal Sciences
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• 제12권5호
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• pp.815-836
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• 1999

The role of animal agriculture for the quality of human life has always been emphasized during 20th century and it is expected to be even more important in terms of food supplies and in providing additional functions in the future. The world human population has almost tripled during a period of half century. The world population of animals has increased 2~3 times (6 times for chicken) during the last 60 years, and the total amount of livestock products has increased 5~6 times (more than 10 times in pork) with higher annual growth rate (9%) in developing countries. Increased personal income certainly encouraged demand for animal products over grains and lower animal production costs resulted from scientific and technological advances. Similarly the production of total grains has more than doubled owing to the advances in agricultural science during the later part of the 20th century. The average life span of world people in 1950s was only 46 years, which will be increased to almost 66 years in the year 2000. Present date clearly indicate that the life span of people is proportional to their income (GNP) and/or animal protein intake. Animals can provide other resources than foods. The increase of human population indicates that the number of animals as well as per capita consumption of animal products will be increased in the 21st century. The other resources we get from animals are drafts, packing, riding, hunting and herding. Guiding the blind, protection and companionship are also examples of what we can expect from animals. In the very near future, animals will become major donors of organs, skin and producers of drugs or special functional foods. It may be concluded that animals are very closely associated and related to the quality of human life, and they are expected to remain the same way in the 21st century.

• Molecules and Cells
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• 제40권1호
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• pp.37-44
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• 2017

PDK1 is essential for T cell receptor (TCR)-mediated activation of $NF-{\kappa}B$, and PDK1-induced phosphorylation of $PKC{\theta}$ is important for TCR-induced $NF-{\kappa}B$ activation. However, inverse regulation of PDK1 by $PKC{\theta}$ during T cell activation has not been investigated. In this study, we found that $PKC{\theta}$ is involved in human PDK1 phosphorylation and that its kinase activity is crucial for human PDK1 phosphorylation. Mass spectrometry analysis of wild-type $PKC{\theta}$ or of kinase-inactive form of $PKC{\theta}$ revealed that $PKC{\theta}$ induced phosphorylation of human PDK1 at Ser-64. This $PKC{\theta}$-induced PDK1 phosphorylation positively regulated T cell activation and TCR-induced $NF-{\kappa}B$ activation. Moreover, phosphorylation of human PDK1 at Ser-64 increased the stability of human PDK1 protein. These results suggest that Ser-64 is an important phosphorylation site that is part of a positive feedback loop for human PDK1-$PKC{\theta}$-mediated T cell activation.

• 동의생리학회지
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• 제14권2호통권20호
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• pp.99-116
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• 1999

This study was undertaken to define the expression rule of six vital substances for human life(六氣) in Meridians and the rule of following of three ${\breve{U}}m$ and three Yan. In order to investigate the expression rule of six vital substances for human life(六氣), incident(標)-fundamental(本) and Ki of middle energizer(中氣) of three ${\breve{U}}m$ and three Yang(三陰三陽) were reviewed. 1, The rule of following is formed centering around fundamental Ki(本氣) between incident(標) and fundamental(本). And in case the ${\breve{U}}m$ and Yang (陰陽) disposition of incident(標) and fundamental(本) is different, whether the ${\breve{U}}m$ and Yang(陰陽) disposition of incident(標) and fundamental(本) is same as those of Ki of middle energizer(中氣), is the key point in following fundamental and activating of the vital energy(氣化). 2. As twelve channels(十二經脈) have not only fundamental Ki(本氣) but also Ki of middle energizer(中氣) at the same time, in expression of six vital substances for human life(六氣), if the fundamental Ki(本氣) is stronger, fundamental Ki(本氣) can be expressed or if the fundamental Ki(本氣) is weaker, Ki of middle energizer(中氣) can be expressed. 3. Twelve channels which is connected with each other through the relation of the interior and the exterior can be regarded as a system, in which Wind(風) and Fire(火), Dryness(燥) and Dampness(濕), Cold(寒) and Heat(熱) maintain balance through mutual control. 4. We can see that in the disease caused by the unbalance of six vital substances for human life(六氣), expression of six pathogenic factor and controlment of six vital substances for human life(六氣) are made up after the following one in the rule of following(從化規律).

• 철학연구
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• 제126권
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• pp.235-261
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• 2013

이 글은 근대에 의한 현대 체제 일반과 그를 극복하려는 탈근대 담론 안에서 왜 로컬 혹은 로컬리티가 필연적으로 인간 삶의 존재론적 '사이'의 문제로 제기될 수밖에 없는지를 철학적으로 조명하려는 시도를 담고 있다. 따라서 우리는 근대와 탈근대의 논의 과정에서 제기된 수많은 문제들 중 인간존재에 대한 근본적인 물음을 제기하면서 동시에 인간 삶의 질을 점검할 필요가 있다(2). 또한 이 과정에서 로컬 혹은 로컬리티는 인간 삶의 질과 어떤 연관성을 맺고 있는지도 자세히 들여다보아야 할 것이다. 왜냐하면 로컬 안에서만 비로소 인간은 다양한 질감의 흔적과 주름들이 뒤엉켜 시간과 장소를 의미화시켜 나가는 주체가 되기 때문이다. 여기서 주체들은 상호주관적 관계망을 통해 사회를 이루고 함께 살아간다는 것을 확인할 수 있다(3). 이럴 때 로컬 혹은 로컬리티는 참된 인간적 사회적 삶이 가능한 장소, 즉 존재론적 '사이'로서 로컬리티 인문학의 가능성으로 드러나게 될 것이다(4).

• 한국경영과학회:학술대회논문집
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• 대한산업공학회/한국경영과학회 1996년도 춘계공동학술대회논문집; 공군사관학교, 청주; 26-27 Apr. 1996
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• pp.450-453
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• 1996

Human sensibility ergonomics is the technology of measuring human sensibility, applying informaiton to the design of products, systems, and environments for convenient, comfort, and safe human use, and pleasuring human life. This study introduce the research contents and strategy on the human sensibility ergonomics project, which started as one of the national research projects of Korea. The objective of the project is to construct the basis of application technology for human-centered products and environments design in order to enhance the competitive power of the products and the quality of human life. The project consists of three main parts, that is, development of fundamental technology for human sensibility, development of simulator for measurement and evaluation of human sensibility, and development of application technology for products and environments. Total research funds is 70million dollars for 7 years.

• 문화기술의 융합
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• 제5권2호
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• pp.305-311
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• 2019

삶의 치유는 무덤으로 통할까, 아니면 죽음이 삶을 치유할 수 있을까. 삶에 있어서의 치유는 삶의 공간의 감정 회로에 존재한다. 그러면 죽음에서의 치유는 어떤 공간에 존재할까. 일단은 죽음에서의 치유는 삶의 너머에 있다. 임제(林悌, 1549~1587)는 그가 사랑하는 황진이의 무덤에서 슬픔의 시조를 읊은 것으로 유명하다. 문학치료를 위해, 이번에는 임제가 황진이의 무덤에서 읊었다고 하는 시조 "청초 우거진 골"의 감정들을 코딩하려고 한다. 이 시조는 사랑과 죽음, 무덤과 슬픔이라는 고통같은 슬픔의 사랑을 노래한다. 즉 사랑과 아픔 혹은 사랑과 이별이라는 상반된 개념이 일으키는 인간의 감정이 어떻게 융합하는지에 관련된 것이다. 임제의 이 시조는 무덤과 사랑과 슬픔이라는 기표들을 융합하여 '인생의 무상함'을 코딩한다. 이 '인생의 무상함'이 이 시조의 문학치료 기능이다. '인생의 무상함'은 인체의 긴장을 풀어주는 치유의 역할을 한다. 이렇게 문학치료가 이루어지면 아무리 고통스러운 삶이라도 우리들은 여유를 가지게 된다. 이 시조에서 전달하는 '인생의 무상함'에 대한 슬픔이 삶 전체를 관조하며 관용하는 문학치료의 효과를 전달하기 때문이다. 앞으로 이러한 연구를 지속하여 새로운 삶에 대한 감정 코딩이 이루어지길 기대한다.

• 생명과학회지
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• 제5권3호
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• pp.117-120
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• 1995

Human milk was examined for antiangiogenic activities by using the chick embryo chorioallantoic membrane (CAM) assay and endothelial cell growth. The low molecular weight (20 KD>$\sim$ ) fraction of human milk stimulated the angiogenesis and increased the endothelial cell growth. These results suggest that the increase of angiogenesis and endothelial cell growth might be attributed to several growth factors and/or angiogenic factors in low molecular fraction (20 KD>$\sim$) of human milk.

• 한국생활과학회지
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• 제15권6호
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• pp.985-997
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• 2006

In this study, we grasped the life time structure according to working woman's income using '2004 life time research' of Korea National Statistical Office. Concrete results are shown as follows. First, inspecting the difference of individual characteristic according to income, young women who have higher education level and larger house area had acquired more income. Second, in case of the difference of life time according to income, there was no difference of individual support time, while there was statistically significant difference of working hours, household affairs, leisure time and moving hours. Third, inspecting the individual time of working, household affairs, bringing up and leisure according to income, there was statistically significant difference by age, education level, sense of time oppression, and fatigue cognition. This individual difference was revealed more strongly in medium to low-ranked group.

• 대한한의정보학회지
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• 제18권1호
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• pp.116-137
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• 2012

The topic of this study is to ask and answer about 'What matters most in medicine'. And the purpose of this study is to establish paradigm which guarantee 'the original principles of science in medicine' and 'the safety of human life in medicine'. The organized characteristics of this study is as follows. 1. 'The harmony of nature (heaven, earth and human)' is the base of medicine. Because medicine control life directly and all life is 'the son of nature'. 2. 'The harmony of Eum and Yang' is the essential power of universe and the key of metabolism of all life including human, animals and plants. Because 'the nature of universe' and all 'Life field' is 'electro-magnetic field'. 3. The Convergence of Oriental medicine and Western medicine orients 'the harmony of Eum and Yang'.

• 생명과학회지
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• 제17권5호
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• pp.671-677
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• 2007

발효 및 비발효 차가버섯 수용성 추출물이 정상 세포주 NIH3T3 mouse normal fibroblast cell 및 인체 종양 세포주 AGS human gastric cancer cell(위암), HCT-15 human colon cancer cell(대장암), Hep3B human hepatoma cancer cell(간암), MCF-7 human breast cancer cell(유방암), HeLa human cervical cancer cell(자궁경부암)에서 MTT(3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide) assay 방법에 의한 세포 증식 억제와 암세포 증식억제의 기전 연구의 일환으로 apoptosis가 일어날 때 나타나는 DNA fragmentation을 agarose gel electrophoresis 방법으로 검토하였다. 인체 종양 세포주의 생육저해 효과가 발효 차가버섯 추출물이 비발효 차가버섯 추출물보다 강한 것으로 나타났다. 그러나 동일한 실험조건하에서 마우스 정상 세포주 NIH3T3은 80% 이상의 생존율을 나타내어 정상 세포주에는 큰 영향을 미치지 않는 것으로 나타났다. 특히, 발효 및 비발효 차가버섯 추출물에서 본 실험에 사용한 세포주 중에서 대장암 세포주 HCT-15에 대해 가장 세포 증식 억제효과가 뛰어났으며, 이러한 효과는 첨가 농도 의존적 이였다. 발효 및 비발효 차가버섯 추출물에 의한 암세포 증식억제가 기전 연구로 apoptosis가 일어날 때 나타나는 DNA fragmentation을 세포로부터 genomic DNA를 분리하여 agarose gel electrophoresis 방법으로 조사한 결과, 정상세포인 NIH3T3 세포는 DNA fragmentation이 거의 일어나지 않아 세포 생존율 결과와 유사한 경향을 보였으나, 특히 대장암 세포주인 HCT-15에서는 발효 차가버섯뿐만 아니라 비발효 차가버섯 추출물에서도 DNA fragmentation이 많이 일어나는 것이 관찰되어 암세포 증식억제 효과가 높다는 결과를 뒷받침 해주고 있다.