• The Korean Society of Law and Medicine
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• v.23 no.3
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• pp.117-137
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• 2022

Today, the medical system is changing into a comprehensive health care system in which collaborative relationships between medical professionals and non-medical personnels in neighboring occupational areas. The current medical act brands such "collaboration" as unlicensed medical practice, and punishes non-medical personnel who acted in the risk management of doctors as well as doctors collaborated with non-medical personnel as unlicensed medical practice. In order to narrow the gap between the legal system that regulates unlicensed medical practices and the medical reality, it is necessary to overcome the structural limitations of dualistic, nationalistic, and identity-oriented regulation of unlicensed medical practices. The legal interests of unlicensed medical practice have a dual nature as a personal legal interest of "human life and body" as well as a national legal interest of "maintenance and protection of the nation's medical license system", and it should be noted that the criteria for judging the legal interests protected by the regulations of criminal punishment should be found in "personal legal interest theory." In addition, when determining which behavior is a medical practice and evaluating its risk, the dimension of behavior and measures should be considered in a fair manner without being biased against the subject (identity) of the action. In other words, judging unlicensed medical practice should depend on whether the risk of side effects that may result from the act is reasonably managed. Considering the prospect of therapeutic dialogue between medical professionals and patients, it would be desirable for medical law policies to move in a way that does not fundamentally block the possibility of collaboration among pluralistic medical personalities.

• 한국노년학
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• v.40 no.4
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• pp.691-706
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• 2020

This study aims to explore health behavior profiles and the association between the derived profiles and living arrangement among middle-aged and older adults. Using data from wave 6 (2016) of the Korean Longitudinal Study of Aging, latent profile analyses were applied to identify patterns of health behaviors and multinomial logistic regression models were conducted to predict profile membership using living arrangement (i.e., living alone, living with spouse only, living with family members) and sociodemographic characteristics. A sample of 7,048 respondents aged 55 and older were included in the study. Results revealed that Korean middle-aged and older adults can be grouped into four health behavior profiles: "High health-compromising" (4%), "Moderate health-compromising" (28%), "Low health-compromising" (65%), and "High physical activity" (3%). Also, living arrangement showed significant profile differences. Compared to the respondents living alone, those living with spouse only were more likely to belong to low and moderate levels of health-compromising behavior profiles than the "High physicial activity profile". Respondents living with family members were more likely to belong to the "High health-compromising profile" than the "High physical activity profile" compared to those living with spouse only. These findings indicate that living arrangement needs to be taken into consideration when developing health promoting programs and supports. Moreover, policy interventions suiting the needs of various sociodemographic subgroups are recommended.

• Nutrition Research and Practice
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• v.16 no.1
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• pp.60-73
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• 2022

BACKGROUND/OBJECTIVES: The extract from Dendropanax morbifera exhibited diverse therapeutic potentials. We aimed to evaluate the efficacy and safety of D. morbifera leaf extract for improving metabolic parameters in human. SUBJECTS/METHODS: A 12-week, double blind, placebo-controlled and randomized trial included a total of 74 adults, and they were assigned to the placebo group (n = 38) or 700 mg/day of D. morbifera group (n = 36). The efficacy endpoints were changes in glycemic, lipid, obesity, and blood pressure (BP) parameters, in addition to the prevalence of metabolic syndrome (MetS) and the numbers of MetS components. Safety was assessed by monitoring adverse events (AEs). RESULTS: After 12 weeks of treatment, the hemoglobin A1c (HbA1c) level significantly decreased in the D. morbifera group compared to that of the placebo group (difference: -0.13 ± 0.20% vs. 0.00 ± 0.28%, P = 0.031; % of change: -2.27 ± 3.63% vs. 0.10 ± 5.10%, P = 0.025). The homeostatic model assessment for insulin resistance level also decreased significantly from its baseline in the D. morbifera group. The systolic BP of D. morbifera group decreased significantly than that of placebo group (difference: -3.9 ± 9.8 mmHg vs. 3.3 ± 11.7 mmHg, P = 0.005; % of change: -2.8 ± 7.7% vs. 3.3 ± 10.2%, P = 0.005). However, the lipid parameters and body composition including body weight did not differ between the groups. The prevalence of MetS (36.8% vs. 13.9%, P = 0.022) and the incidence of MetS (10.5% vs. 13.9%, P = 0.027) at 12 weeks was significantly lower in the D. morbifera group than it was in the placebo group. No serious AEs occurred in either group. CONCLUSIONS: Supplementation with D. morbifera extracts over a 12-week period improved metabolic parameters such as HbA1c and BP and reduced the prevalence of MetS.

• Journal of Food Hygiene and Safety
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• v.37 no.5
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• pp.364-371
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• 2022

The bones of the human body support the structures of the body and provide protection for a person's internal organs. Bone metabolic diseases are on the rise due to a significant increase in life expectancy over a short period of time. Therefore, we investigated the osteoblast differentiation promoting and osteoclastogenesis inhibitory activities of fermented Benincasa hispida cong. (HR1901-BS, HR1901-BSaf). We evaluated the alkaline phosphatase (ALP) activity of MC3T3-E1 mouse calvarial-derived osteoblasts. We also evaluated expression of ALP, osteocalcin (OCN), and runt-related transcription factor 2 (Runx2), which regulate osteoblast differentiation. To assess effects on osteoclast formation, tartrate-resistant acid phosphatase (TRAP) activity in RAW264.7 cells was analyzed. ALP activity increased by 121-136% and 140-156%, respectively in the presence of HR1901-BS and HR1901-BSaf. Expression of osteoblast differentiation factor also increased significantly. We also confirmed that HR1901-BS and HR1901-BSaf decreased TRAP activity in osteoclasts by 35-47% and 23-39%, respectively. Our results showed that fermented Benincasa hispida cong. (HR1901-BS, HR1901-BSaf) increase bone mineralization and osteoblast differentiation activity in MC3T3-E1 cells, and inhibit bone resorption activity in RAW264.7 cells. In conclusion, fermented Benincasa hispida cong. (HR1901-BS, HR1901-BSaf) can be used as an effective natural resource for preventing and treating bone-related diseases.

• Korean Journal of Remote Sensing
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• v.38 no.5_3
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• pp.811-818
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• 2022

Recently, the number of natural and environmental disasters is rapidly increasing due to extreme weather caused by climate change, and the scale of economic losses and damage to human life is increasing accordingly. In addition, with urbanization and industrialization, the characteristics and scale of extreme weather appearance are becoming more complex and large in different ways from the past, and need for remote sensing and artificial intelligence technology for responding and managing global environmental disasters. This special issue investigates environmental disaster observation and management research using remote sensing and artificial intelligence technology, and introduces the results of disaster-related studies such as drought, flood, air pollution, and marine pollution, etc. in South Korea performed by the i-SEED (School of Integrated Science for Sustainable Earth and Environmental Disaster at Pukyong National University). In this special issue, we expect that the results can contribute to the development of monitoring and management technologies that may prevent environmental disasters and reduce damage in advance.

• Journal of the Korean Institute of Traditional Landscape Architecture
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• v.39 no.1
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• pp.20-30
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• 2021

The purpose of this study was to identify the ecological characteristics of Namhan Mountain Fortress Walls vascular plants through investigation and analysis of Namhan Mountain Fortress Walls and to provide basic data when establishing a plan for conservation and management of Namhansanseong Fortress Wall vascular plants. The result of this survey revealed 249 taxa composed of 77 families, 169 genera, 222 species, 5 subspecies, 19 varieties and 3 forms. In terms of life form of Namhan Mountain Fortress Walls, the appearance rate of Hemicryptophytes(H) was high. Rare plants was 1 taxa and Korea endemic plants was 5 taxa. The total number of floristic regional indicator plants was 15 taxa, gradeI 9 taxa, gradeII 2 taxa, gradeIII 3 taxa, gradeIV 1 taxa. Among them, Polygala tatarinowii Regel is considered to the most important(gradeIV), and it is first description because in Gyeonggi-do, as no additional forms have been confirmed other than this site. Plants identified as rock vegetation were found in 21 taxa. Invasive alien plants were identified 20 taxa. Plants distributed on the walls of Namhan Mountain Fortress, such as Aconitum longecassidatum Nakai, Clematis heracleifolia DC. var. tubulosa (Turcz.) Kuntze, Hylotelephium spectabile (Boreau) H.Ohba and Polygala tatarinowii Regel etc, are feared to decrease the number of species and individuals due to the loss of walls, the spread of invasive alien plant and human interference, so conservation and management measures are needed.

• Journal of Popular Narrative
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• v.26 no.2
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• pp.123-153
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• 2020

As the importance of documented fact has weakened in historical dramas, the combination with other genres has become prominent. By reviewing the way romance is dealt with in historical dramas, this research examines how the properties of historical events adopted by historical dramas are related to the motif of love, and how the narrative of love and romance contributes to the historical effects, with a focus on the television drama Mr. Sunshine. Mr. Sunshine is the first historical drama written by Kim Eun-sook, combining deliberately rearranged history with the writer's unique grammar of romance. The failed resistance movement of the righteous army in the drama is matched with the love that cannot be achieved based on self-negation. The drama, which deals with the tyranny of Japanese imperialism and the independence of Joseon, fictionalizes key characters and events, transforming the desire of love into the passion of patriotism. Romance in Mr. Sunshine serves as a catalyst for emphasizing the tragedy of historical events and reconstitutes cultural memories. In historical dramas, the fictional plot of romance leads viewers to reflect on human life in history that flows from the past to the future. How does an individual's inner feelings contribute to the historical representation? This research is significant as it is the first attempt to examine the relationship between historical drama and romance in various ways.

• Journal of Korea Entertainment Industry Association
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• v.14 no.6
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• pp.77-89
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• 2020

The film "Parasite" portrays Korea's history and its present in a space that clearly represents the real world's hierarchy as a vertical structure. It demonstrates the problems of an insurmountable reality and the elements of various conflicts occurring below the surface of Korean society through a complex mix of human emotions and relationships. The most realistic yet unrealistic characters cross boundaries between being victims and perpetrators, defamiliarizing ordinary scenes from everyday life through their small mistakes, strange obsessions, bizarre behavior, anxious psychology, and desperate struggles. This study analyzes the expression of the film "Parasite" through its characters with the belief that the film expresses director Bong Joon-ho's consistent cinematic philosophy of taking reality beyond the traditional rules of film genres. By doing so, Bong creates a feature of the expression that shifts genres as the characters' personalities amplify related behaviors, conflicts and questions, and that this is the core of the unique nuance and distinct humor of this film. In addition, the personalities of the characters interact with all the film's elements (cinematic techniques, space, props, etc.), evoking effects of various meanings, which are transmitted through the actors'images and acting. In this respect, the study analyzes how the actors were cast in order to realistically reproduce the characters of the actors, how their acting was harmonized with the film's elements, and its features as well as how they were expressed.

• Animal Bioscience
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• v.36 no.1
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• pp.29-42
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• 2023

Objective: Pigs, an ideal biomedical model for human diseases, suffer from about 50% early embryonic and fetal death, a major cause of fertility loss worldwide. However, identifying the causal variant remains a huge challenge. This study aimed to detect single nucleotide polymorphisms (SNPs) and candidate genes for the number of mummified (NM) piglets using the imputed whole-genome sequence (WGS) and validate the potential candidate genes. Methods: The imputed WGS was introduced from genotyping-by-sequencing (GBS) using a multi-breed reference population. We performed genome-wide association studies (GWAS) for NM piglets at birth from a Landrace pig populatiGWAS peak located on SSC11: 0.10 to 7.11 Mbp (Top SNP, SSC11:1,889,658 bp; p = 9.98E-13) was identified in cyclin dependent kinase on. A total of 300 Landrace pigs were genotyped by GBS. The whole-genome variants were imputed, and 4,252,858 SNPs were obtained. Various molecular experiments were conducted to determine how the genes affected NM in pigs. Results: A strong GWAS peak located on SSC11: 0.10 to 7.11 Mbp (Top SNP, SSC11:1,889,658 bp; p = 9.98E-13) was identified in cyclin dependent kinase 8 (CDK8) gene, which plays a crucial role in embryonic retardation and lethality. Based on the molecular experiments, we found that Y-box binding protein 1 (YBX1) was a crucial transcription factor for CDK8, which mediated the effect of CDK8 in the proliferation of porcine ovarian granulosa cells via transforming growth factor beta/small mother against decapentaplegic signaling pathway, and, as a consequence, affected embryo quality, indicating that this pathway may be contributing to mummified fetal in pigs. Conclusion: A powerful imputation-based association study was performed to identify genes associated with NM in pigs. CDK8 was suggested as a functional gene for the proliferation of porcine ovarian granulosa cells, but further studies are required to determine causative mutations and the effect of loci on NM in pigs.

• Journal of Navigation and Port Research
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• v.46 no.4
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• pp.338-343
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• 2022

As the revitalization of the global maritime industry continues, the number of foreign ships navigating the maritime territories of maritime neighboring countries has rapidly increased. However, large-scale marine accidents have occurred, caused by the insufficient establishment of a system for management and operation relative to vessels' safety-condition. To address that, the IMO has granted the right to exercise port state control, especially for foreign vessels, to countries with jurisdiction over maritime territories with strengthening regulations and guidelines. In particular, the Republic of Korea, as a member of the TOKYO MOU, is conducting PSC, but as of 2020, the proportion of foreign ships was three times higher than that of national ships that called in domestic ports. However, the inspection rate was low at 9% which has not met the recommended level by the TOKYO MOU. Thus, this study conducted an IPA analysis as well as content analysis, by collecting the practical opinions and views of PSCO through objective questionnaires and written expert interviews, for improving the efficiency and effectiveness of domestic PSC. As a result, it was derived that the importance and performance related to human factors such as life on board, working environment, and response to safety accidents should be improved in to raise the quality of PSC inspection. Additionally, the work environment and performance of PSC in domestic ports for foreign vessels could be improved, if multifaceted support bases are established, for administrative unification of related tests for PSC, recruitment of PSCO, activation of the defection-reporting system, reorganization of the PSC execution group, etc.