• Title/Summary/Keyword: human injury

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Protective Effect of Kakkalide from Puerarie Flos on Ethanol-Induced Lethality and Hepatic Injury Is Expressed by Human Intestinal Microflora

  • Han, Yeo-Ok;Han, Myung-Joo;Park, Sung-Hwan;Kim, Dong-Hyun
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.225.2-226
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    • 2003
  • The inhibitory effect of kakkalide isolated from Puerariae flos on ethanol-induced lethality and hepatic injury were investigated. Intraperitoneally treated Kakkalide was weakly reduced the mortality associated with administration of ethanol and did not reduce alcohol hepatotoxicity. However, orally administered kakkalide and intraperitoneally administered irisolidone significantly reduced serum ALT and AST activities on liver-injured mice by ethanol. (omitted)

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Development of Pedestrian Dummies with Korean Anthropometric Data (한국인 표준체형을 고려한 보행자 더미 개발)

  • Shin D.H.;Kim K.H.;Son K.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2006.05a
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    • pp.523-524
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    • 2006
  • It is necessary to have a model that describes the anthropometry of the crash victim with a sufficient accuracy Koreans, however, do not have their own pedestrian dummies to be used in pedestrian collision tests. They have to use European and American dummies for their safety analysis. In this study scaled pedestrian dummies were constructed by using MADYMO. The dummies represent Korean average males and females aged from 25 to 29. The scaled Korean dummies and MADYMO human models were used to obtain and compare the pedestrian dynamic behaviors and injury criteria during the impact events.

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Balloon Angioplasty for Budd-Chiari Syndrome Resulting from Primary Repair of an Inferior Vena Cava Injury (하대정맥 손상후 일차봉합술로 인해 발생한 버드-키아리 증후군 환자를 혈관성형술로 치료한 증례보고)

  • Sim, Joohyun;Won, Je Hwan;Jung, Kyoungwon;Lee, Cook John;Kim, Young Hwan
    • Journal of Trauma and Injury
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    • v.27 no.4
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    • pp.196-200
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    • 2014
  • Budd-Chiari syndrome is an uncommon condition characterized by hepatic outflow obstruction. Direct suture of the injured Inferior vena cava in a patient with blunt hepatic trauma also may cause an equivalent condition. However, early diagnosis is possible with common symptoms and radiologic evaluation. Moreover, a transluminal approach with balloon angioplasty could prevent long-term complications of Budd-Chiari syndrome without repeated abdominal surgery.

Development of a Model for the Analysis of Occupant Response subjects in Low-Speed Rear-End Collision (저속 후방 추돌에 따른 승객 거동 현상 해석용 모델 개발)

  • 김희석;김영은
    • Transactions of the Korean Society of Automotive Engineers
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    • v.8 no.3
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    • pp.139-150
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    • 2000
  • Although a number of neck injuries are generated, the data which quantify the kinematic response of the human head and cervical spine in low-speed rear-end automobile collisions is very limited. On this problem, just few in vitro experimental research or some experimental research using dummy on neck injury by rear-end collision was conducted, thus systematic research is requested on full scale injury mechanism. An occupant model for the response of the occupant subject to rear-end collision using commercial dynamics package DADS was developed. Developed model shows more close agreement with the experimental data compared with the MADYMO simulation results for the cases of ${\delta}V=16$ kph in sled test. For the case of ${\delta}V=8$ kph and 33.5 kph with production seat, model also shows its reliable response compared with experimental results using Hybrid III and Hybird III with RID.

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Analysis of Two Electrocution Accidents in Greece that Occurred due to Unexpected Re-energization of Power Lines

  • Baka, Aikaterini D.;Uzunoglu, Nikolaos K.
    • Safety and Health at Work
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    • v.5 no.3
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    • pp.158-160
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    • 2014
  • Investigation and analysis of accidents are critical elements of safety management. The over-riding purpose of an organization in carrying out an accident investigation is to prevent similar accidents, as well as seek a general improvement in the management of health and safety. Hundreds of workers have suffered injuries while installing, maintaining, or servicing machinery and equipment due to sudden re-energization of power lines. This study presents and analyzes two electrical accidents (1 fatal injury and 1 serious injury) that occurred because the power supply was reconnected inadvertently or by mistake.

Actoprotective effect of ginseng: improving mental and physical performance

  • Oliynyk, Sergiy;Oh, Seikwan
    • Journal of Ginseng Research
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    • v.37 no.2
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    • pp.144-166
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    • 2013
  • Actoprotectors are preparations that increase the mental performance and enhance body stability against physical loads without increasing oxygen consumption. Actoprotectors are regarded as a subclass of adaptogens that hold a significant capacity to increase physical performance. The focus of this article is studying adaptogen herbs of genus Panax (P. ginseng in particular) and their capabilities as actoprotectors. Some animal experiments and human studies about actoprotective properties of genus Panax attest that P. ginseng (administered as an extract) significantly increased the physical and intellectual work capacities, and the data provided suggests that ginseng is a natural source of actoprotectors. Preparations of ginseng can be regarded as potential actoprotectors which give way to further research of its influence on physical and mental work capacity, endurance and restoration after exhaustive physical loads while compared with reference actoprotectors.

A study on Standard Safety Operation Evaluation Method for Improving Safety Activity (안전활동 개선을 위한 표준 안전작업 평가기법 설계)

  • Yang, Kwang-Mo;Yang, Hyun-Hoo;Kang, Yun-Jin;Kang, Kyung-Sik
    • Journal of the Korea Safety Management & Science
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    • v.9 no.4
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    • pp.39-47
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    • 2007
  • An industrial injury prevention has a basis on fundamental spirit of human respect rather than only injury prevention in company. The employer should recognize employee as a core part of an industrial management and use as a starting point of safety and health management rather than means of production. There are many reason for unsafety action without safety operation. The reason is no standard safety operation in company or the workers never get a enough education. Standard safety operation is prepared by paper for accurate directions and orders and operators must read the paper to prevent an error of action. Also an essential particular is safety of equipment and machine must be assumed to establish standard safety operation then safety of operations will be possible.

Human Sting of Cephalonomia gallicola (Hymenoptera: Bethylidae) in Korea

  • Lee, In-Yong;Shin, Chang-Seob;Sim, Seobo;Park, Jung-Won;Yong, Tai-Soon
    • Parasites, Hosts and Diseases
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    • v.52 no.6
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    • pp.681-684
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    • 2014
  • Hymenoptera stings can cause serious injury to humans. We report the clinical findings of 6 cases of Hymenoptera stings. All patients developed painful erythematous papules at the sting sites and had a past history of parasitoid wasp sting. This is the first clinical report of the parasitoid wasp, Cephalonomia gallicola, causing human stings in Korea.

The Development of the Korean Life Change Unit Model for Accident Prevention - Focused on the Married Workers Living in the Middle Area - (재해방지를 위한 한국형 생활변화단위 모형의 개발 - 중부지역 거주 기혼 근로자를 중심으로 -)

  • Kang Young-Sig;Choi Man-Jin
    • Journal of the Korean Society of Safety
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    • v.19 no.3 s.67
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    • pp.118-123
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    • 2004
  • The more the lift environment eastern idea, culture, factory automation system and information technology complicates, the more the various human error brings about. It brings about all kind of accidents and occupational diseases. Also the death and sickness or injury by psychological stress among the human error has increased every year. Therefore this paper describes the Korean lift change unit model through statistical testing with the proposed life change unit factors on the married workers living the middle area. The proposed model can be simply used in order to minimize the industrial accident and human error in real fields. Finally, the result will be helpful for the better safety management.

Inhibitory Effects of PD98059, SB203580, and SP600125 on α-and δ-granule Release and Intracellular Ca2+ Levels in Human Platelets

  • Kwon, Hyuk-Woo
    • Biomedical Science Letters
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    • v.24 no.3
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    • pp.253-262
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    • 2018
  • Platelets are activated at sites of vascular injury via several molecules, such as adenosine diphosphate, collagen and thrombin. Full platelet aggregation is absolutely essential for normal hemostasis. Moreover, this physiological event can trigger circulatory disorders, such as thrombosis, atherosclerosis, and cardiovascular disease. Therefore, platelet function inhibition is a promising approach in preventing platelet-mediated circulatory disease. Many studies reported the involvement of mitogen-activated protein kinases (MAPKs) signaling pathways in platelet functions. However, these studies were limited. Thus, we examined MAPK signaling pathways in human platelets using specific MAPK inhibitors, such as PD98059, SB203580, and SP600125. We observed that these inhibitors were involved in calcium mobilization and influx in human platelets. They also suppressed thrombin-induced ${\alpha}$- and ${\delta}$-granule release. These results suggest that PD98059, SB203580, and SP600125 exhibit $Ca^{2+}$ antagonistic effects.