Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
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- Pages.225.2-226
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- 2003
Protective Effect of Kakkalide from Puerarie Flos on Ethanol-Induced Lethality and Hepatic Injury Is Expressed by Human Intestinal Microflora
- Han, Yeo-Ok (Department of Food Science and College of Pharmacy, Kyung Hee University) ;
- Han, Myung-Joo (Department of Food Science and College of Pharmacy, Kyung Hee University) ;
- Park, Sung-Hwan (Department of Food Science and College of Pharmacy, Kyung Hee University) ;
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Kim, Dong-Hyun
(Department of Food Science and College of Pharmacy, Kyung Hee University)
- Published : 2003.04.01
Abstract
The inhibitory effect of kakkalide isolated from Puerariae flos on ethanol-induced lethality and hepatic injury were investigated. Intraperitoneally treated Kakkalide was weakly reduced the mortality associated with administration of ethanol and did not reduce alcohol hepatotoxicity. However, orally administered kakkalide and intraperitoneally administered irisolidone significantly reduced serum ALT and AST activities on liver-injured mice by ethanol. (omitted)
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