• Applied Biological Chemistry
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• v.50 no.4
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• pp.352-357
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• 2007

For a correlation to study the five tastes and efficacies in oriental medicine concepts, we used herbal medicines with bitter taste character in traditionally effective and experimental methods. In this study, we tested the in vitro effect of 20 typical kinds of herbal medicines with bitter taste on platelet aggregation induced by collagen in human whole blood using the impedance method of aggregometry. Among them, 3 kinds of hot water extracts and 2 kinds of 70% ethanol extracts showed the significant inhibiting effect on whole blood aggregation $(^{***}p<0.001)$. In particular, Coptidis Rhizoma (Coptis chinensis) extracts were selected as the most effective candidate with a strong grade of bitter taste through the sensory test of trained panels. The results from this experiment provide pharmacological evidence for the traditional use of bitter tasting herbs with traditional medicine theory, suggesting that strong bitter taste herbs could be help problems of blood circulation more than mild bitter tasting herbs.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.9
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• pp.5796-5800
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• 2014

This paper presents reconfigurable beam steering patch antenna with high gain for a wireless headset. Because existing antenna for wireless communication in headsets has an omni-directional radiation pattern, it has a deleterious effect in the vicinity of the human head. To reduce this effect, this paper proposed an antenna comprised of a U-slot and manufactured on a FR-4 substrate. The antenna operating at the 2.37-2.5 GHz band used a tapered matching method to match the impedance between the feed part and patch part. To implement the beam steering capability, the antenna used two PIN diodes. Using PIN diodes, the antenna presented three states ($S_0$, $S_1$ and $S_2$) in the maximum beam directions of the YZ-plane ($0^{\circ}$, $30^{\circ}$ and $330^{\circ}$, respectively). The peak gains of the antenna in the headset were 4.22-5.15 dBi. The fabricated antenna could communicate efficiently with a wireless headset.

• Journal of Preventive Medicine and Public Health
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• v.33 no.2
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• pp.193-198
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• 2000

Objective : To evaluate the relationship between serum leptin concentration and obesity indices in a rural population. Methods : Two hundred and nine subjects were randomly sampled from 1036 residents who had participated in the survey. Their obesity indices were measured by bioelectrical impedance analysis and anthropometry. Serum leptin concentrations were measured by immunoradiometric assay. Results : Serum leptin concentrations were positively correlated with body mass index, percent of body fat, fat mass, waist circumference, and hip circumference. Serum leptin concentrations were higher in obese or overweighted subjects than normal or thin subjects(8.5[0.9-31.4] compared with $2.7[0.1-12.0]{\mu}g/L$, p<0.01). Serum leptin concentrations were higher in women than men, even after an adjustment to body mass index$(\beta=4.183,\;p<0.01)$. According to body composition, serum leptin concentrations were more related with waist circumference in men, hip circumference in women. Conclusions : Serum leptin concentrations are positively correlated with obesity indices. Serum leptin concentrations are higher in obese subjects, in women, and more related with peripheral obesity. These findings support the hypothesis that human obesity is associated with leptin-resistance rather than leptin-deficiency.

• Journal of Biomedical Engineering Research
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• v.23 no.4
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• pp.269-279
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• 2002

When we inject a current into an electrically conducting subject such as a human body, voltage and current density distributions are formed inside the subject. The current density within the subject and injection current in the lead wires generate a magnetic field. This magnetic flux density within the subject distorts phase of spin-echo magnetic resonance images. In Magnetic Resonance Current Density Imaging (MRCDI) technique, we obtain internal magnetic flux density images and produce current density images from $\bigtriangledown{\times}B/\mu_\theta$. This internal information is used in Magnetic Resonance Electrical Impedance Tomography (MREIT) where we try to reconstruct a cross-sectional resistivity image of a subject. This paper describes numerical techniques of computing voltage. current density, and magnetic flux density within a subject due to an injection current. We use the Finite Element Method (FEM) and Biot-Savart law to calculate these variables from three-dimensional models with different internal resistivity distributions. The numerical analysis techniques described in this paper are used in the design of MRCDI experiments and also image reconstruction a1gorithms for MREIT.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.24 no.1
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• pp.1-10
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• 2013

In this paper, a broadband planar monopole antenna for multi-band services is proposed. The physical size of the proposed antenna is miniaturized by folding a rectangular loop. And a resonance point in the 3.9 GHz band is reduced by a coupling phenomenon with the central part of the T-shaped patch and the folded rectangular loop. In addition, the T-shaped patch is inserted to the rectangular shaped monopole antenna due to deriving the broadband frequency characteristics. The frequency characteristic is optimized by adjusting the gap and length of the folded rectangular loops and a transverse diameter of the T-shaped patch. The antenna dimensions including the ground plane are $40{\times}60{\times}1.6mm^3$. It is fabricated on the FR-4 substrate(${\epsilon}_r$=4.4) using a microstrip line of $50{\Omega}$ for impedance matching. In the measured result, the bandwidth corresponding to the VSWR of 2:1 is 162 MHz(815~977 MHz) and 2,530 MHz(1.43~3.96 GHz). For analyzing the human effect by the proposed antenna, 1 g and 10 g averaged SARs are simulated and measured. As the simulated results, 1 g-averaged SAR is 1.044 W/kg, and 10 g-averaged SAR is 0.718 W/kg. This result are satisfied by the SAR guidelines which are 1.6 W/kg(1 g-averaged) and 2.0 W/kg(10 g-averaged).

• Journal of the Institute of Electronics Engineers of Korea TE
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• v.39 no.2
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• pp.34-43
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• 2002

In this paper, with the reference of the pulse wave acquired by the pulse-checking device, it is measured the impedance on the key measuring points of the 12 kyungmaks of the human body's left and right by using 24-channels Yangdorak machine. Then, based on the Fuzzy theory, this study diagnosed the each meridian's strength and weakness. After that, both the strengthening and weakening stimulus of magnetic fields are applied to the dominant direction to find out how the degree of strength and weakness of the meridian changed. Ultimately, the magnetic therapy that can stimulate the magnetic field at the time of diagnosis and thereby balancing the interactive of five-system(O-hang) have been materialized. For the stimulation of magnetic fields, a stimulating device which can change the direction and time on a specific part of the key measuring points of the limbs of 24 kyungmaks have been developed and used. The therapeutic methods are as follows. First, the strength and weakness of the meridian have been determined. Second, both the extremely weak meridian of Yin(Shade) and Yang(Shine), and the extremely strong meridian of Yin and Yang were adjusted by applying appropriate ascending and descending stimuli respectively. All these adjusting processes can now be carried out automatically on a personal computer(PC). 

• Journal of Nutrition and Health
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• v.41 no.4
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• pp.307-316
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• 2008

The purpose of the study was to investigate nutritional status of chronic obstructive pulmonary disease (COPD) patients and to find out the differences according to the stages of disease. From March to October, 2006, 41 stable male patients of mild to severe COPD patients were recruited from Seoul National University hospital. The patients' of body weight and fat free mass were assessed by bioelectrical impedance analysis. The nutritional status of the patients was also assessed by 3-day recall, index of nutritional quality (INQ), dietary diversity score (DDS), dietary variety score (DVS), food group index pattern and dietary quality index (DQI). The total of 41 patients were classified into three groups, stage I, stage II and stage III groups according to the classification of Global Initiative for Chronic Obstructive Lung Disease (GOLD) standard. The mean age of the patients in each stage were 67.2-66.9 years showing no significant difference. The ratio of $FEV_1$/FVC were $57.5{\pm}7.3$, $46.9{\pm}7.6$ and $38.2{\pm}6.8%$, respectively showing significant differences according to the stages of disease. The fat free mass of the stage II ($48.2{\pm}4.7kg$) and III ($47.3{\pm}4.5kg$) was significantly lower than that of stage I ($53.1{\pm}6.9kg$) patients. There were significant correlation of fat free mass with $FEV_{1}$, and BMI (body mass index) with $FEV_{1}$/FVC ratio (p < 0.05). COPD patients showed the diet-related clinical symptoms of anorexia, dyspnea, dyspepsia, and chewing difficulty. Daily intakes of calorie, K, vitamin $B_2$ and folate of the patients were very low ($83.8{\pm}20.7%$, $58.9{\pm}14.4%$, $70.7{\pm}19.6%$ and $74.4{\pm}10.2%$, respectively) however, they did not significantly different according to the stages of disease. Daily intake of calcium was significantly lower in the stage III patients (p < 0.05). The mean scores of dietary variety score was significantly lower in the stage III patients (p < 0.001). Dietary quality index of the patients were not different among the stages of disease and the scores indicated poor quality of diet. As a summary, we found that body fat free mass, regularity of exercise, frequency of having snacks and dietary variety score were significantly associated with the severity of chronic obstructive pulmonary disease.

• Journal of the Korean Society of Marine Environment & Safety
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• v.24 no.4
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• pp.459-466
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• 2018

Hazardous and Noxious Substances (HNS) are defined as substances that are likely to create a significant impact on human health and marine ecosystem when they are released into the marine environment. Recently, as the volume of HNS transported by ships increases, the rate of leakage accidents also increases. Therefore, research should be conducted to control and monitor sunken materials from the viewpoint of technology development for hazardous material leakage accident response. In this paper, acoustic detection experiments were carried out using HNS substitute materials in order to confirm the possibility of acoustic detection of sunken HNS on the sediment. The castor oil, which has a similar acoustic impedance with chloroform, is used as a substitute. 200 kHz high frequency signals were used to discriminate the reflected signals and measure reflection loss from the interface between water and castor oil. The reflection loss measured is in good agreement with the modeling results, showing a possibility of acoustic detection for sunken HNS.

• Journal of Advanced Navigation Technology
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• v.25 no.6
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• pp.536-542
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• 2021

In this paper, we proposed a triple band printed monopole antenna with a bent branch strips for WiFi / 5G. An antenna structure in which bent strips for generating multiple resonance are attached in the form of branches was newly proposed based on a typical monopole strip vertically erected as a triple band antenna structure. The proposed antenna is designed on a FR-4 substrate with dielectric constant 4.3, thickness of 1.6 mm, and size of 28×40 mm². The measured impedance bandwidth is 430 MHz (2.22~2.65 GHz) in the 2.4 GHz WLAN, 450 MHz (3.38~3.83 GHz) in the 3.5 GHz and 2390 MHz (4.95~7.34 GHz), In particular, it has been observed that antenna has a stable omnidirectional radiation patterns as well as gain of 1.537 dBi, 1.878 dBi and 2.337 dBi in the entire frequency band of interest.

• Journal of Korea Entertainment Industry Association
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• v.13 no.2
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• pp.197-205
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• 2019

This study was to compare arterial stiffness and hemodynamic responses between male smokers and non-smokers. This study also investigates the influences of smoking before exercise on arterial stiffness and hemodynamic responses. 24 male subjects of age 20-29 without history of cardiorespiratory disease were divided into smokers and non-smokers. Smokers had more than 5 years of smoking experience. In order to evaluate the effects of pre-exercise smoking, smokers were tested twice, once with a cigarette before the exercise and the other once without one. Data was collected from bio-impedance analysis, SphygmoCor XCEL, graded exercise test, and fitness test. Main results of this study are as follows: First, there are differences between smokers and non-smokers in cardiorespiratory and hemodynamic response functions, as shown by maximal oxygen consumption, exercise duration, and heart rate. Second, the although the arterial stiffness between smokers and non-smokers showed statistically significant differences in the speed of the pulse wave velocity and augmentation index, smoker had a faster rate. It shows that smoking behavior has a negative impact on the cardiovascular system. Third, pre-exercise smoking behavior does have an impact on cardiorespiratory and hemodynamic response functions, as shown by exercise duration and heart rate. Lastly, arterial stiffness between smokers and non-smokers showed statistically not significant in the speed of the pulse wave velocity and augmentation index. However, the difference was not statistically significant. Brachial systolic pressure, a component of pulse wave analysis, on the other hand, was significantly dependent on pre-exercise smoking behavior. Subjects who participated in this study are college students in early 20s. Given their relatively short history of smoking, it is possible that their smoking habits are not severe enough to develop into cardiorespiratory or cardiovascular diseases. But Smokers showed lower levels of cardiopulmonary functions, as maximal oxygen consumption and exercise duration than nonsmokers.