• Biotechnology and Bioprocess Engineering:BBE
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• v.3 no.1
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• pp.1-5
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• 1998

One cervical cancer cell line, C9, carrying human papillomavirus type 18 (HPV18) genes that is one of the major etiologic concoviruses for cervical cancer was characterized. This cell line was further characterized for its capacity related to the epithelial cell proliferation, stratification and differentiation in reconstituted artificial epithelial tissue. The in vitro construction of three dimensional artificial cervical opithelial tissue has been engineered using C9 epithelial cancer cells, human foreskin fibroblasts and a matrix made of type I collagen by organotypic culture of epithelial cells. The morphology of paraffin embedded artificial tissue was examined by histochemical staining. The artificial epithelial tissues were well developed having multilayer. However, the tissue morphology was similar to the cervical tissus having displasia induced by HPV infection. The characteristics of the artificial tissues were examined by determinining the expression of specific marker proteins. In the C9 derived artificial tissues, the expression of EGF receptor, as epithelial proliferation marker proteins for stratum basale was observed up to the stratum spinosum. Another epithelial proliferation marker for stratum spinosum, cytokerations 5/6/18, were observed well over the stratum spinosum. For the differentiation markers, the expression of involucrin and filaggrin were observed while the terminal differentiation marker, cytokeratins 10/13 was not detected at all. Therefore the reconstituted artificial epithelial tissues expressed the same types of differentiation marker proteins that are expressed in normal human cervical epithelial tissues but lacked the final differentiation capacity representing characteristics of C9 cell line as a cancer tissue devived cell line. Expression of HPV18 E6 oncoprotein was also observed in this artifical cervical opithelial tissue though the intensity of the staining was weak. Thus this artificial epithelial tissue could be used as a useful model system to examine the relationship between HPV-induced cervical oncogenesis and epithelial cell differentiation.

• Proceedings of the KSAR Conference
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• 2004.06a
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• pp.275-275
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• 2004

To evaluate the potential of the stem cell therapy as a method for prenatal management of spinal open neural tube defect (ONTD), the influence of embryonic stem cells injected into the amniotic cavity on the re-closure capacity of spinal ONTD was investgated. Spinal neural tube was incised open for a length of 6 somites using chick embryos of Hamburger and Hamilton stage 18 or 19. (omitted)

• Journal of Contemporary Eastern Asia
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• v.14 no.2
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• pp.37-44
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• 2015

Many people criticized how the Chinese government responded to the Wenchuan Earthquake. They focused on how it failed to address the psychological needs of the survivors. The study presented here approached this issue from a human resources perspective. It was determined that the Chinese government approached the situation in a bureaucratic way that limited the government's capacity and barred non-profit organizations and community groups from participating. It was also found that survivors could not contact these organizations for psychological support. This study concludes that the situation called for a more flexible and improvised institution that would respond to the emerging needs of survivors.

• Journal of the Korean Society of Clothing and Textiles
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• v.24 no.7
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• pp.1073-1080
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• 2000

Moisture transfer property of fabrics has known as one of the most important factors deciding wearer's subjective comfort not only thermally but also of sensorial. As a decisive property of fabric materials in determining human sensorial comfort, moisture vapor management property of heat resistant workwear material was examined in terms of increasing and decreasing rate and maximum value of relative humidity in the microclimate under the sweat pulse situation. An unique moisture regulation index, B$_{d}$, was calculated from the measurements using a novel dynamic sweating hot plate apparatus and was used to assess the buffering capacity of fabrics against a moisture vapor sweat pulse.e.

• Journal of Yeungnam Medical Science
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• v.26 no.1
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• pp.1-14
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• 2009

Human bone marrow-derived mesenchymal stem cells (MSCs) are a rare population of undifferentiated cells that have the capacity of self renewal and the ability to differentiate into mesodermal phenotypes, including osteocytes, chondrocytes, and adipocytes in vitro. Recently, MSCs have been shown to reside within the connective tissue of most organs, and their surface phenotype has been well analyzed. Many reports showed that transplanted MSCs enhanced regeneration as well as functional improvement of damaged organs and tissues. The wide differentiation plasticity of MSCs was expected to contribute to their demonstrated efficacy in a wide variety of experimental animal models and in human clinical trials. However, new findings suggest that the ability of MSCs to alter the tissue microenvironment via secretion of soluble factors may contribute more significantly than their capacity for differentiation in tissue repair. This review describes what is known about the cellular characteristics and differentiation potential of MSCs, which represent a promising stem cell population for further applications in regenerative medicine.

• Journal of Korean Society for Quality Management
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• v.21 no.2
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• pp.215-223
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• 1993

A paired comparison which is a method of comparative judgements is widely used to increase the amount of information transmitted to human sense organ. In this study, a paired comparison method is proposed for the discrimination capacity and preference analysis of non-skilled sensory inspectors. We consider on order effect, that is, difference of evaluation occurred as a result of sample presentation by random order. The purpose of this paper is to determine a sample with the highest preference degrees by analyzing a discrimination capacity and evaluating preference degrees of sensory inspectors. An analysis of a discrimination capacity is bared on the capacity index obtained by an eigen-vector method and an evaluation of preference degrees is performed by a significance test.

• Journal of Biomedical Engineering Research
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• v.3 no.1
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• pp.49-50
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• 1982

In this paper, the information capacity, the intergrate performance measure of digital radiography system has been quantitatively analyzed. The effect of various factors affecting the information capacity of the digital radiography system in multi-stage detection processes has been considered and analyzed in detail. The results show that the more information capacity can be obtained with the smaller detector cell area, despite of the reduced signal to noise ratio due to the reduced number of X-ray photons per detector cell. Considering the limit of human visual acuity. however, the sufficient resolution will be obtained when the detector cell size in 0.2${\times}$0.2mm with 8 bit quantizaion. And also the results indicates that the information capacity may be severely reduced by the mixture of electric noise in final read-out stage.

• Bulletin of the Korean Chemical Society
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• v.31 no.9
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• pp.2557-2560
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• 2010

To assay for antioxidant capacity of natural products considered important in producing human health benefits, a practical and economical method using pellet techniques was developed. A standard visualizing reagent, 1,1diphenyl-2-picryl-hydrazyl (DPPH), was mixed with a water-miscible polyvinyl alcohol (PVA), serving as a solid phase support for the DPPH reagent. A DPPH pellet was prepared by dropping a small volume of the DPPH solution onto PET film, and drying in an oven. The PVA-based DPPH pellet was dissolved into water, in which the water-miscible PVA plays as a non-ionic surfactant to help the DPPH reagent to be dissolved into the solvent. Using the DPPH assay, the antioxidant capacity of water-soluble extracts of black soybean, barley, green tea, and green gram was examined. Among the natural products tested, green tea showed the highest antioxidant capacity. This PVA-based DPPH antioxidant assay can be further applied in the natural food, raw plant material, and health product inspection field.

• The Journal of Asian Finance, Economics and Business
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• v.8 no.11
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• pp.31-39
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• 2021

This study empirically examines the proposition that the domestic fundamentals of a nation can emerge as absorptive capacity factors to reap the benefits of inward FDI. The study is contextualized in Asia, set from1982 to 2017, and data is grouped into low-income and lower-middle-income economies, in comparison to high-income and upper-middle-income economies, catering to different geographical regions within Asia. The investigation is based on a series of absorptive capacity factors such as infrastructure, human capital, domestic credit, and health indicator. The methodological analysis is premised on dynamic panel structure and employs the Generalized Method of Moments (GMM) estimation technique. The empirical findings suggest that that the infrastructure variable appears to be the major absorptive capacity factor for both groups of countries. The health indicator, on the other hand, can help reap the benefits of inward FDI, but only if the threshold level is met. The selected economies must achieve this threshold level to reap the benefits of FDI. To absorb the benefits of inward FDI, countries must be proactive in providing sound infrastructure and implementing proper healthcare measures.

• Molecules and Cells
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• v.41 no.7
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• pp.613-621
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• 2018

The capacity of differentiation of human pluripotent stem cells (hPSCs), which include both embryonic stem cells and induced pluripotent stem cells, into cardiomyocytes (CMs) in vitro provides an unlimited resource for human CMs for a wide range of applications such as cell based cardiac repair, cardiac drug toxicology screening, and human cardiac disease modeling. However, their applicability is significantly limited by immature phenotypes. It has been well known that currently available CMs derived from hPSCs (hPSC-CMs) represent immature embryonic or fetal stage CMs and are functionally and structurally different from mature human CMs. To overcome this critical issue, several new approaches aiming to generate more mature hPSC-CMs have been developed. This review describes recent approaches to generate more mature hPSC-CMs including their scientific principles, advantages, and limitations.