• 한국산학기술학회논문지
• /
• 제5권1호
• /
• pp.1-6
• /
• 2004

휘발성유기 화합물(Vo1ati1e Organic Compounds : VOCs)은 탄화수소 화합물을 총칭한다. 이는 오존 및 광화학 스모그의 원인물질일 뿐 아니라 인체에는 암을 유발시키는 유해 물질이다. 또한 대기 중 악취 물질로서 환경 및 건강에 영향을 초래하는 유해성 물질이다. 본 논문은 대기 중에 포함된 암을 유발시키는 유해성 물질인 BTX(Benzene, Toluene, Xylene)의 존재 유무와 농도 측정에 대해서 연구하였다. 다종의 가스센서를 어레이하여 BTX 가스를 측정하고 인공신경망(Artificial Neural Network : ANN)의 역전파(Back propagation : BP) 알고리즘으로 시뮬레이션과 실험을 통해 농도를 추론하였다. ANN모듈은 기준 데이터를 시뮬레이션을 통해 학습시키고, 가스를 주입하여 실험 할 때 학습된 델타 모델에 근거하여 추론을 할 수 있는 추론 알고리즘 모듈이다. 이 모듈은 기준데이터를 MATLAB 코드로 시뮬레이션을 하여 생성된 parameter를 가지고 수행했으며, 시뮬레이션 결과를 실험을 통해 비교 테스트하여 검증하였다.

• International Journal of Contents
• /
• 제16권1호
• /
• pp.75-86
• /
• 2020

As the elderly population is becoming an aging society, the elderly are experiencing many problems. Social security costs for the elderly are increasing and the un-linked social phenomenon is emerging. Thus, the social infrastructure and welfare system established in the past economic growth period are in danger of not functioning properly. People socially isolated or with chronic diseases among the elderly are exposed to various accidents. Thus, an active healthcare management service is imperative. Additionally, in the event of a dangerous situation, the system must have ways to notify guardians (family or medical personnel) regarding appropriate action. Thus, in this paper, we propose the smartphone-based healthcare and emergency response service platform. The proposed service platform aggregates movement of relevant data in real-time using a smartphone. Based on aggregated data, it will always recognize the user's movements and current state using the human motion recognition mechanism. Thus, the proposed service platform provides real-time status monitoring, activity reports, a health calendar, location-based hospital information, emergency situation detection, and cloud messaging server-based efficient notification to several subscribers such as family, guardians, and medical personnel. Through this service, users or guardians can augment the level of care for the elderly through the reports. Also, if an emergency situation is detected, the system immediately informs guardians so as to minimize the risk through immediate response.

• Journal of Information Processing Systems
• /
• 제13권4호
• /
• pp.876-892
• /
• 2017

A virtual reality is a virtual space constructed by a computer that provides users the opportunity to indirectly experience a situation they have not experienced in real life through the realization of information for virtual environments. Various studies have been conducted to realize virtual reality, in which the user interface is a major factor in maximizing the sense of immersion and usability. However, most existing methods have disadvantages, such as costliness or being limited to the physical activity of the user due to the use of special devices attached to the user's body. This paper proposes a new type of interface that enables the user to apply their intentions and actions to the virtual space directly without special devices, and test content is introduced using the new system. Users can interact with the virtual space by throwing an object in the space; to do this, moving object detectors are produced using infrared sensors. In addition, the users can control the virtual space with their own postures. The method can heighten interest and concentration, increasing the sense of reality and immersion and maximizing user's physical experiences.

• Molecules and Cells
• /
• 제42권1호
• /
• pp.1-7
• /
• 2019

Macrophage is an important innate immune cell that not only initiates inflammatory responses, but also functions in tissue repair and anti-inflammatory responses. Regulating macrophage activity is thus critical to maintain immune homeostasis. Tyro3, Axl, and Mer are integral membrane proteins that constitute TAM family of receptor tyrosine kinases (RTKs). Growing evidence indicates that TAM family receptors play an important role in anti-inflammatory responses through modulating the function of macrophages. First, macrophages can recognize apoptotic bodies through interaction between TAM family receptors expressed on macrophages and their ligands attached to apoptotic bodies. Without TAM signaling, macrophages cannot clear up apoptotic cells, leading to broad inflammation due to over-activation of immune cells. Second, TAM signaling can prevent chronic activation of macrophages by attenuating inflammatory pathways through particular pattern recognition receptors and cytokine receptors. Third, TAM signaling can induce autophagy which is an important mechanism to inhibit NLRP3 inflammasome activation in macrophages. Fourth, TAM signaling can inhibit polarization of M1 macrophages. In this review, we will focus on mechanisms involved in how TAM family of RTKs can modulate function of macrophage associated with anti-inflammatory responses described above. We will also discuss several human diseases related to TAM signaling and potential therapeutic strategies of targeting TAM signaling.

• 문화기술의 융합
• /
• 제9권6호
• /
• pp.1065-1071
• /
• 2023

본 논문에서는 주거지 내의 재실자의 행동을 분류하기 위한 LSTM 모델을 개발하는 연구에 대해 다룬다. 다중센서의 구성은 실내 공기질을 측정하는 IAQ(Indoor air quality) 센서, 재실감지 및 위치를 추적하는 UWB 레이더, 재실자의 생체정보를 측정하기 위한 Piezo 센서로 구성되며 실제 주거환경과 유사한 실험환경을 구축하여 외출, 재실, 요리, 청소, 운동, 수면 등의 재실자 행동 데이터를 수집한다. 수집한 데이터를 이상치와 결측치를 전처리 후 LSTM 모델을 사용하여 재실자 행동 분류 모델의 정확도, 민감도, 특이도, 그리고 T1스코어를 계산 후 평가한다.

• International Journal of Oral Biology
• /
• 제33권4호
• /
• pp.163-177
• /
• 2008

Periodontal disease, a form of chronic inflammatory bacterial infectious disease, is known to be a risk factor for cardiovascular disease (CVD). Porphyromonas gingivalis has been implicated in periodontal disease and widely studied for its role in the pathogenesis of CVD. A previous study demonstrating that periodontopathic P. gingivalis is involved in CVD showed that invasion of endothelial cells by the bacterium is accompanied by an increase in cytokine production, which may result in vascular atherosclerotic changes. The present study was performed in order to further elucidate the role of P. gingivalis in the process of atherosclerosis and CVD. For this purpose, invasion of human aortic smooth muscle cells (HASMC) by P. gingivalis 381 and its isogenic mutants of KDP150 ($fimA^-$), CW120 ($ppk^-$) and KS7 ($relA^-$) was assessed using a metronidazole protection assay. Wild type P. gingivalis invaded HASMCs with an efficiency of 0.12%. In contrast, KDP150 failed to demonstrate any invasive ability. CW120 and KS7 showed relatively higher invasion efficiencies, but results for these variants were still negligible when compared to the wild type invasiveness. These results suggest that fimbriae are required for invasion and that energy metabolism in association with regulatory genes involved in stress and stringent response may also be important for this process. ELISA assays revealed that the invasive P. gingivalis 381 increased production of the proinflammatory cytokine interleukin (IL)-$1{\beta}$ and the chemotactic cytokines (chemokine) IL (interleukin)-8 and monocyte chemotactic (MCP) protein-1 during the 30-90 min incubation periods (P<0.05). Expression of RANTES (regulation upon activation, normal T cell expressed and secreted) and Toll-like receptor (TLR)-4, a pattern recognition receptor (PRR), was increased in HASMCs infected with P. gingivalis 381 by RT-PCR analysis. P. gingivalis infection did not alter interferon-$\gamma$-inducible protein-10 expression in HASMCs. HASMC nonspecific necrosis and apoptotic cell death were measured by lactate dehydrogenase (LDH) and caspase activity assays, respectively. LDH release from HASMCs and HAMC caspase activity were significantly higher after a 90 min incubation with P. gingivalis 381. Taken together, P. gingivalis invasion of HASMCs induces inflammatory cytokine production, apoptotic cell death, and expression of TLR-4, a PRR which may react with the bacterial molecules and induce the expression of the chemokines IL-8, MCP-1 and RANTES. Overall, these results suggest that invasive P. gingivalis may participate in the pathogenesis of atherosclerosis, leading to CVD.

• 한국생활과학회지
• /
• 제19권6호
• /
• pp.1083-1094
• /
• 2010

The purpose of this study is to provide a fundamental research data that is necessary in an education of dietary life so that the students have sound dietary life through a right food purchase after investigating perception of children's dietary habit and activity, food labelling, and nutrition labelling for 400 students of the 5 and 6th grades. The result of the study are as followings. In terms of perception questions over food labelling, on the whole, "know it little bit" was the highest. Girls and country was higher than boys and city. A list of item that is important in contents of food labelling were period of circulation, data of manufacturing, price, used ingredient, origin of product, nutrition contain labelling, manufacturer, quantity in contents(quantity, the number). A meaningful difference was shown in gender(p<.05) and area(p<.01). In 30 perception questions over nutrition labelling, "know it little bit" was the most, and girls and country were higher than boys and city. In ascertaining nutrition labelling at the time of purchasing the food, "look often" was the most. Girls and city were higher than boys and Gun in average but no difference was statistically shown in knowledge mark in utilization and perception of nutrition labelling. The response rate in girls(p<.01) and country(p<.05) was higher in a question of "if nutrition labelling is displayed, nutriment that is harmful for our body will be eaten less" and girls' response rate was higher in the question of "being educated for my health". Therefore, practice centered nutrition education is necessary to purchase the food after ascertaining food nutrition labelling out of an attitude in habitually purchasing the processed food. The students develop comprehensible food nutrition labelling the direction to emphasizing nutrition educational labelling and recognizing that the healthy nutriment is contained without conventional and food safety centered labelling should be changed.

• 사상체질의학회지
• /
• 제31권1호
• /
• pp.26-35
• /
• 2019

The purpose of this study is to understand how Sasang Constitutional Medicine has been understood in China. Methods I searched for topics in Chinese such as Sasang medicine (四象醫學), Sasang constitution (四象體質), Chao medicine (朝醫), philosophy (哲學), principles (原理), the school of Confucianism (儒家), Confucianism (儒學) and ideology (思想) in CNKI database on January 15, 2019. The selected studies were summarized as three sections; the basic principles of Sasang Constitutional Medicine, influences of Confucianism and comparison with other medicines. Results In China, the principles of Sasang Constitutional Medicine is explained using the concepts such as Heaven-Human-Nature-Order, the Great Ultimate (Taiji), Two Modes (Liang-Yi), Sasang, heart, sorrow-anger-joy-pleasure, nature-emotions (Xingqing), and viscera-bowels (Zang-Fu). Sasang Constitutional Medicine is considered to has been influenced by Confucianism. The form of Sasang Constitutional Medicine was affected by the Book of Changes (Zhouyi), and the contents were impacted by the Great Learning (Daxue), the Doctrine of the Mean (Zhongyong), the Mencius (Mengzi) and the Analects (Lunyu). Sasang Constitutional Medicine have distinctive characteristics in comparison with other medicines, such as inherent determinations of constitution, organs difference by constitution the actions of nature, emotions and desire, recognition of humans as social beings, and the signification of heart as a presiding center. Conclusion In China, the philosophy of Sasang Constitutional Medicine has been studied with basis of four-element structure; activity, mind, body and matter. Also, it has been researched in medical aspects of human trying to control the nature and emotions to be physically, mentally and socially healthy.

• 한국정보통신학회논문지
• /
• 제24권9호
• /
• pp.1224-1230
• /
• 2020

스마트폰의 보급 이후 웨어러블 디바이스에 대한 관심이 높아지고 다양화되면서 사용자들의 생활에 밀접하게 연관되고 있으며, 개인화된 서비스를 제공하기 위한 방법으로 사용되고 있다. 본 논문에서는 스마트폰에 내장된 3축 가속도 센서와 3축 자이로 센서의 정보를 합성곱 신경망에 적용하여 사용자의 행동을 검출하는 방법을 제안한다. 인간의 행동은 동작의 크기와 범위에 따라서 동작을 구성하는 신호 데이터의 지속시간을 포함한 시작 시점과 끝나는 시점이 다르다. 이로 인해 합성곱 신경망에 그대로 적용하면 행동 인식 정확도에 대한 성능상의 문제가 있다. 따라서 센서 데이터를 시간의 구간에 따라 분할된 특징을 학습하는 시분할 특징 융합 합성곱 신경망(TDFFCNN: Time-Division Feature Fusion Convolutional Neural Network)을 제안하였다.

• 한국콘텐츠학회논문지
• /
• 제13권12호
• /
• pp.869-879
• /
• 2013

현대의학으로 아직 정복 하지 못한 암 질환에 대하여 치료행위 중 하나인 방사선치료에 참여하고 있는 전문직군에 대한 행위의 정당성과 적정 인력에 대하여 분석 하였다. 방사선종양학과(치료방사선과)가 설치된 의료기관에서 의학물리사의 역할이 현행 법 테두리 안에서 준 면허행위임에 틀림없으나 그 행위의 정당성을 부여받을 수 있는 현행 법 규정이 명확하지 않다. 따라서 국외 의학물리사의 인증자격 및 시험 등 제도를 조사하여 국내 규정에 반영할 수 있는 방안을 모색하였다. 더불어 의학물리사 행위가 위법성이 내재된 분야중 하나이기에 그 위법성을 조각할 수 있는 내용 중심으로 "의료법"과 "원자력안전법","의료분야의 방사선 안전관리에 관한 기술기준"에 따라 재해석 하였다. 결론적으로 "의료법"과 "의료분야의 방사선 안전관리에 관한 기술기준"에 합치되는 자격으로 인정하여, 증가하고 있는 방사선치료행위와 방사선 피폭의 안전관리에 대처해야 함이 타당할 것이다.