• Journal of Periodontal and Implant Science
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• 제25권2호
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• pp.253-266
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• 1995

Recently, available interests concerning the biologic significance of the extracellular matrix and proliferating cells associated with periodontal disease has been increased. The distribution or expression of cellular proliferation by PCNA, macrophage detection by ${\alpha}$-l-antichymotrypsin, fibronectin playing a important role in host defence mechanisms indirectly, and transglutaminase that cross linked to fibronectin and stimulate fibrin stabilization were studied in inflammed and healthy gingiva. The excised tissue samples were fixed neutral formalin for 24 hours, embedded with paraffin, sectioned at 4-61lffi in thickness, and immunohistochemically processed by LSAB method. The positive reaction to PCNA was localized in the suprabasal and basal layer of inflammed gingiva and an increasing reactivity was observed than healthy gingiva. ${\alpha}$-I-antichymotrypsin positive cells were localized in the basal layer of inflammed gingiva, and there was no or rare positive cells in healthy gingiva. The positive reaction to fibronectin in inflammed gingiva was more than healthy gingiva,"and shown in the connective tissue subjacent to basement membrane of epithelium and in the periphery of the collagen fiber bundles. The positive cells by transglutaminase in inflammed gingiva were noted in suprabasal, spinous, and keratin layer of epithelium, and slightly increased in the capillaries of connective tissues. But the results of this study demonstrated in vitro reaction. Therefore, the role of PCNA,${\alpha}$-l-antichyrnotrypsin, transglutaminase, fibronectin and coefficient with other growth factor and extracellular matrix were further investigated in vivo.

• 한국컴퓨터정보학회논문지
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• 제16권2호
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• pp.9-16
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• 2011

GPU는 저렴한 비용으로 쉽게 대규모 데이터 병렬성을 활용할 수 있는 장점을 갖고 있어 많은 고성능 컴퓨팅 응용 분야에서 사용되고 있는 추세다. 행렬의 고유벡터를 구하는 power method는 웹 페이지의 중요도를 계산하는 PageRank 알고리즘 등 여러 응용 분야에서 활용되고 있는 방법으로써, 본 연구에서는 power method를 GPU에서 병렬화하여 구현하였으며, 성능을 최적화하기 위한 개선 방법을 제시하였다. Power method는 행렬과 벡터의 곱셈 연산이 반복적으로 수행되며 GPU에서 쉽게 병렬화가 가능하다. 그러나, 고유벡터의 수렴 여부 판단을 위한 연산 등의 작업과 다음 곱셈을 위한 벡터 크기의 조정 등의 작업이 부가적으로 필요하며, 이러한 작업은 GPU 내의 커널 코드를 여러 차례 호출하고 불필요한 데이터 이동을 유발하는 문제점이 있다. 본 연구에서는 커널 호출 회수를 줄이고 스레드 배치를 최적함과 동시에 수렴 여부 판단을 위한 연산을 최적함으로써 power method의 성능을 향상시켰다.

• Archives of Plastic Surgery
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• 제46권3호
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• pp.204-213
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• 2019

Background In implant-based breast reconstruction, acellular dermal matrix (ADM) is essential for supporting the inferolateral pole. Recent studies have compared non-sterilized freeze-dried ADM and sterilized pre-hydrated ADM, but have not assessed whether differences were attributable to factors related to sterile processing or packaging. This study was conducted to compare the clinical outcomes of breast reconstruction using two types of sterile-processed ADMs. Methods Through a retrospective chart review, we analyzed 77 consecutive patients (85 breasts) who underwent tissue expander/implant breast reconstruction with either freeze-dried ADM (35 breasts) or pre-hydrated ADM (50 breasts) from March 2016 to February 2018. Demographic variables, postoperative outcomes, and operative parameters were compared between freeze-dried and pre-hydrated ADM. Biopsy specimens were obtained for histologic analysis. Results We obtained results after adjusting for variables found to be significant in univariate analyses. The total complication rate for freeze-dried and pre-hydrated ADMs was 25.7% and 22.0%, respectively. Skin necrosis was significantly more frequent in the freeze-dried group than in the pre-hydrated group (8.6% vs. 4.0%, P=0.038). All other complications and operative parameters showed no significant differences. In the histologic analysis, collagen density, inflammation, and vascularity were higher in the pre-hydrated ADM group (P=0.042, P=0.006, P=0.005, respectively). Conclusions There are limited data comparing the outcomes of tissue expander/implant breast reconstruction using two types of sterile-processed ADMs. In this study, we found that using pre-hydrated ADM resulted in less skin necrosis and better integration into host tissue. Pre-hydrated ADM may therefore be preferable to freeze-dried ADM in terms of convenience and safety.

• Advances in materials Research
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• 제2권1호
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• pp.37-49
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• 2013

The transition metal salt doped solid polymer electrolyte [TSPE] were prepared with HPMC as a host polymer. The virgin and doped films were prepared by solution-casting method and investigated using wide angle X-ray scattering method. Micro structural parameters like lattice strain (g%), stacking/twin faults, the average number of unit cells counted in a direction perpendicular to the Bragg's plane (hkl) spacing of (hkl) planes dhkl, crystallite size Ds, distortion width, standard deviation were determined by whole pattern powder fitting (WPPF) method, which is an extension of single order method. It is found that the crystallite size decreases with the increase in the content of $FeCl_3$. This decrease is due to increase in localized breaking of polymer network which also accounts for the amorphous nature of the material. The filler inorganic salt $FeCl_3$ acts as plasticizer. FTIR study also confirms and justifies the interaction between the polymer and in-organic salt in the matrix. Physical properties like mechanical stability and Ac conductivity in these films are in conformity with the X-ray results.

• Transactions on Electrical and Electronic Materials
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• 제15권4호
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• pp.175-181
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• 2014

In this paper, the simulation and modeling of a polyethylene/clay nanocomposite were undertaken to predict the nanocomposite's dielectric behavior and to help design a nanocomposite material with optimum electrical properties for electrotechnical or electronic applications. A 3-D simulation model using the finite elements method was employed in order to study the effective permittivity and electric field distribution of two-phase nanocomposite materials for ordered and random distributions of inclusions in a low-loss host matrix such as polyethylene. The influence of the dispersion of reinforcing particles, and of the permittivity and radius of the inclusions, was analysed. The simulation results were compared with alternative, known theoretical solutions obtained from classical models, and were found to be in good agreement. The numerical results also indicate that for fixed volume fractions of nanoparticles the effective permittivity of the mixture, for ordered and random distributions, does not vary with the degree of dispersion. The variation of the effective permittivity with the particle radius is shown, using numerical data, to agree with the analytical modules.

• The Plant Pathology Journal
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• 제30권1호
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• pp.10-24
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• 2014

Genetic diversity and differentiation of 50 Colletotrichum spp. isolates from legume crops studied through multigene loci, RAPD and ISSR analysis. DNA sequence comparisons by six genes (ITS, ACT, Tub2, CHS-1, GAPDH, and HIS3) verified species identity of C. truncatum, C. dematium and C. gloeosporiodes and identity C. capsici as a synonym of C. truncatum. Based on the matrix distance analysis of multigene sequences, the Colletotrichum species showed diverse degrees of intera and interspecific divergence (0.0 to 1.4%) and (15.5-19.9), respectively. A multilocus molecular phylogenetic analysis clustered Colletotrichum spp. isolates into 3 well-defined clades, representing three distinct species; C. truncatum, C. dematium and C. gloeosporioides. The ISSR and RAPD and cluster analysis exhibited a high degree of variability among different isolates and permitted the grouping of isolates of Colletotrichum spp. into three distinct clusters. Distinct populations of Colletotrichum spp. isolates were genetically in accordance with host specificity and inconsistent with geographical origins. The large population of C. truncatum showed greater amounts of genetic diversity than smaller populations of C. dematium and C. gloeosporioides species. Results of ISSR and RAPD markers were congruent, but the effective maker ratio and the number of private alleles were greater in ISSR markers.

• Parasites, Hosts and Diseases
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• 제37권1호
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• pp.39-46
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• 1999

As a preliminary study for the explanation of pathobiology of Neodiplostomum seoulense infection. a 54 kDa protease was purified from the crude extract of adult worms by sequential chromatographic methods. The crude extract was subjected to DEAE-Sepharose Fast Flow column, and protein was eluted using 25 mM Tris-HC1 (pH 7.4) containing 0.05. 0.1, 0.2 and 0.4 M NaC1 in stepwise elution. The 0.2 M NaCl fraction was further purified by Q-Sepharose chromatography and protein was eluted using 20 mM sodium acetate (pH 6.4) containing 0.05, 0.1. 0.2 and 0.3 M NaCl, respectively. The 0.1M NaCl fraction showed a single protein band on SDS-PAGE carried out on a 7.5-15% gradient gel. The proteolytic activities of the purified enzyme were specifically inhibited by L-trans-epoxy-succinylleucylamide (4-guanidino) butane (E-64) and iodoacetic acid. The enzyme, cysteine protease. showed the maximum proteolytic activity at pH 6.0 in 0.1 M buffer, and degraded extracellular matrix proteins such as collagen and fibronectin with different activities. It is suggested that the cysteine protease may playa role in the nutrient uptake of N. seoulense from the host intestine.

• BMB Reports
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• 제41권2호
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• pp.102-107
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• 2008

Extracellular proteases play an important role in a wide range of host physiological events, such as food digestion, extracellular matrix degradation, coagulation and immunity. Among the large extracellular protease family, serine proteases that contain a "paper clip"-like domain and are therefore referred to as CLIP-domain serine protease (clip-SP), have been found to be involved in unique biological processes, such as immunity and development. Despite the increasing amount of biochemical information available regarding the structure and function of clip-SPs, their in vivo physiological significance is not well known due to a lack of genetic studies. Recently, Drosophila has been shown to be a powerful genetic model system for the dissection of biological functions of the clip-SPs at the organism level. Here, the current knowledge regarding Drosophila clip-SPs has been summarized and future research directions to evaluate the role that clip-SPs play in Drosophila immunity are discussed.

• 한국콘텐츠학회논문지
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• 제16권4호
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• pp.224-230
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• 2016

최근 인터넷 멀티미디어 서비스의 폭발적인 증가에 따라 급증하는 데이터 트래픽을 효율적으로 전송하기 위한 콘텐츠 중심 네트워크에 대한 연구가 국내외적으로 활발하다. 콘텐츠 중심 네트워크는 기존의 호스트 중심의 전송방식에서 벗어나 콘텐츠를 중심으로 데이터 트래픽을 전송하는 네트워킹 방법이다. 본 논문에서는 기존의 시뮬레이션과 달리 수리적인 접근 방법을 이용하여 두 개 라우터로 구성된 콘텐츠 중심 네트워크의 캐싱 성능을 분석한다. 통신 네트워크의 확률적 상황을 고려하여 라우터가 두 개인 콘텐츠 중심 네트워크의 캐싱시스템을 이차원의 연속시간 마코프체인으로 모형화한다. 전이율행렬의 구조를 분석하여 캐싱 성능치의 수치해를 유도하고 다양한 수치 예제를 제시한다.

• Journal of Information Processing Systems
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• 제12권4호
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• pp.765-778
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• 2016

In watermarking schemes, the discrete wavelet transform (DWT) is broadly used because its frequency component separation is very useful. Moreover, LU decomposition has little influence on the visual quality of the watermark. Hence, in this paper, a novel blind watermark algorithm is presented based on LU transform and DWT for the copyright protection of digital images. In this algorithm, the color host image is first performed with DWT. Then, the horizontal and vertical diagonal high frequency components are extracted from the wavelet domain, and the sub-images are divided into $4{\times}4$ non-overlapping image blocks. Next, each sub-block is performed with LU decomposition. Finally, the color image watermark is transformed by Arnold permutation, and then it is inserted into the upper triangular matrix. The experimental results imply that this algorithm has good features of invisibility and it is robust against different attacks to a certain degree, such as contrast adjustment, JPEG compression, salt and pepper noise, cropping, and Gaussian noise.