• Journal of Acupuncture Research
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• 제22권2호
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• pp.1-12
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• 2005

Objective: With the onset of stroke, white blood cells release several proinflammatory cytokines, including interleukin (IL)-6, IL-10, and tumor necrosis factor $(TNF)-{\alpha}$. It has been proven in previous studies that the release of these cytokines is related to the extent of damage to the brain and to overall prognosis. However, no studies have yet been performed to determine the connection with IL-6 and IL-10. Thus, this study is performed to see whether polymorphisms of IL-6, IL-10, and $TNF-{\alpha}$ genes that show increased serum concentration with the onset of stroke are related to stroke attack in Koreans. Methods : Peripheral blood samples derived from patients with stroke (n=100) and healthy controls (n=100) were taken under informed consent. In subjects with stroke, blood samples were obtained within 24 hours of stroke onset. Genomic DNA was isolated using the Wizard DNA Purification Kit (Promega, Madison, WI). Results : 1. Subjects with Heterozygote (GA) and Homozygote (AA) $TNF-{\alpha}$ gene types showed 2.433 and 20.457 times higher risks of being attacked by stroke, respectively, compared to subjects with wild type (GG) $TNF-{\alpha}$ gene type. The data was still statistically significant after adjusting for age, sex, history of smoking, and history of alcohol drinking. 2. Subjects with Homozygote (CC) IL-6 gene type showed 182.033 times higher risk of being attacked by stroke, compared to subjects with wild type (GG) IL-6 genes. This data was statistically insignificant (p=0.700). The data was still statistically insignificant after adjusting for age, sex, history of smoking, and history of alcohol drinking. 3. Subjects with Heterozygote (GA) and Homozygote (GG) IL-10 gene types showed 8.785 and 3.303 times higher risks of being attacked by stroke, respectively, compared to subjects with wild type (AA) IL-10 genes. The data was still statistically insignificant after adjusting for age, sex, history of smoking, and history of alcohol drinking. Conclusion : Our results suggest that the investigated $TNF-{\alpha}$ and IL-10 gene polymorphisms play an important role in stroke attack, but IL-6 gene polymorphism has not been found to associated with stroke.

• 한국학교보건학회지
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• 제26권3호
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• pp.144-157
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• 2013

Purpose: Health management programs should provide comprehensive health services for students and staffs at schools. Health management programs are critical for helping students become adults with physically, mentally, and socially good health conditions. The aim of this study was to identify the past and present history of health management programs and health laws to help schools develop future health plans. Methods: This study was conducted by analyzing reference data collected using data from Ministry of Education and Science Technology, Korean Educational Development Institute, Korea Centers for Disease Control and Prevention, and National Statistical Office as well as legal documents from the Legislative Office related to school health from 2001 to 2010. Results: Health management programs in schools included three sections: disease prevention and control, physical examinations, and prevention of communicable diseases. Disease prevention and controls consisted of obesity control, drug abuse prevention and control,and management of students' mental health. Various strategies and services were developed to improve health status of students for 10 years from 2001 to 2010. School health laws and systems have been established for disease prevention, physical examinations and communicable disease control as well, to improve students' health as well. Conclusion: The history of health management programs has a number of implications to help design future plans for school health programs and services for students and staffs.

• 건축역사연구
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• 제5권2호
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• pp.83-95
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• 1996

Computerized visual database construction of architectural precedents has just begun in some research institutes in the world. In Korea the first visual database has shown its testl version by S architectural design firm in september 1996. In this article the author discusses the historical contexts and the recent computerization cases, the traits, the uses and the limits of architectural visual database system of precedents. The forms and contents of data fields in two cases are compared with a focus on the description of architectural traits of each data entry. Compared to the KIA format, the S database has better performance for architectural design reference because it collects more pictures and drawings and larger texts for the field of architectural chracteristics. But this latter also is constrained by its capacity of memory and so lacks the reciprocity of the DOORS in the Graduate School of Design, Harvard University. A visual database system which has more flexible allocation of memory and respondent with the users is yet to be prepared. But this system also should be maintained by some experts in architectural history, theory and criticism, because their knowledge is essential for selection of precedents and revision of the data description. A full-fledged electronic visual database in architecture will not only save much effort for the architect, but also will change the architects' design behavior. Nevertheless this does not mean the automatic promotion of architects' creativity.

• 한국한의학연구원논문집
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• 제15권1호
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• pp.91-94
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• 2009

Understanding the present condition of Oriental traditional medicine in different country is demanded for the Korean Traditional Medicine to prepare his orientation in future. Also it is not possible to separate the present condition of OTM from history of oriental medicine as a whole. This is valid for the introduction of TCM in the west. The first information have arrived in Europe by the terrestrial and maritime travelers accounts. The diplomatic way, with special reference to Jesuit fathers, has brought cultural and theoretical precise data. The physicians of East India Company and, later, of expeditionary forces, have supplied with practical data. Five periods follow one another: 1) Period when the source reached and are used in Europe. This first step is intimately involved with the use and comparison of similar factor between the two medical systems ; 2) "Discovery" and use of needles ; 3) latent period when techniques coming from acupuncture source were developed ; 4) "Chinese Acupuncture" correctly speaking ; 5) modern period or investigating period, when Eastern and Western people are trying to correlate data of traditional medicine with those of western science. In particular the actual situation from 2000.

• 한국공간정보시스템학회 논문지
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• 제2권2호
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• pp.127-142
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• 2000

지리정보 시스템은 토지와 관련한 속성 데이터와 공간 데이터의 통합 정보를 저장하고 저장된 데이터를 분석할 수 있다. 대부분의 지리정보 시스템은 토지의 현재 정보만을 지원한다. 그러나 토지에 대한 소유권 분쟁이나 토지 정책 수립에 필요한 통계 정보는 현재 정보뿐만 아니라 과거의 이력 정보를 필요로 한다. 따라서, 이 논문에서는 효율적으로 이력 정보를 관리할 수 있는 시공간 연산자를 설계 및 구현하였다. 이 연산자들은 GIS 기반 토지대장/지적도 이력관리 시스템에서 사용된다. 이력 정보는 시공간 연산자의 공간 연산에 의해 발생되며, 구현된 연산자는 이력 정보를 저장하고, 관리할 수 있는 기능을 제공한다.

• 한국콘텐츠학회:학술대회논문집
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• 한국콘텐츠학회 2008년도 춘계 종합학술대회 논문집
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• pp.575-578
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• 2008

현재 대부분의 자동차 부품 제조업체에서는 자동차 부품개발 및 구매, 생산 관리 등에 어려움을 격고 있으며, 자동차 부품의 신규 개발 및 설계 변경 시 신규 등록 및 이력 관리에 어려움이 있다. 이에 따라 여러 가지 부품에 대한 자동화된 이력관리와 부품의 데이터베이스 구축에 대한 필요성을 절실히 느끼고 있는 상항이다. 이에 본 논문은 자동차 제조 부품관련 데이터 검색과 실시간 생산통합관리 시스템 개발을 위한 설계를 목적으로 한다. 설계 데이터 변경에 대한 자재변경과정을 입력함으로써 자동적으로 데이터 갱신이 이루어질 수 있도록 하였고, 부품에 대한 품명, 품번을 입력하면 관련 부품 이력정보의 통합관리가 가능하도록 하였다.

• 이베로아메리카
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• 제12권1호
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• pp.241-265
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• 2010

The main purpose of this study is to reveal the historical origins of Latin American economic underdevelopment, by answering two research questions; 1)'Why is Latin America underdeveloped?' and 2)'How has colonial experience impacted on the economic growth in Latin America?' First, this essay analyzes long-term tendency of growth domestic product(GDP) per capita data. The data verify that current underdevelopment of Latin American economy is the result of economic stagnation during the eighteenth and nineteenth centuries, when Latin America suffered political and economic instability before and after the independence from Spain and Portugal. It elucidates that colonial experience affected on the economic growth in Latin America. Second, this essay reviews key independent variables of the relationship between colonial experience and economic growth in Latin America. To do so, the study categorizes extant literature into two groups according to the type of its independent variables: 1)internal factor and 2)external factor. Finally, the essay surveys the role of institutions in Latin American economic growth and development. The survey confirms that the importance of institutions in the study of Latin American economic history. In addition, the essay suggests some tasks for further research in Latin American economic history; 1)the construction of basic economic data, 2)the substantialization of the role and characteristics of institutions, and 3)the expansion of research on institutions which overcomes ideological rigidity of existing institutional approach.

• 한국CDE학회논문집
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• 제8권2호
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• pp.90-100
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• 2003

Engineering change (EC) objects are the data structure and related operations that can support applications for EC procedures or processes. Their functionalities include controlling management data, specifying related product structure, and archiving a history of product structure changes for EC management. In this paper we introduce a systematic approach to support the propagation of changes between different product structure views using the history of structure changes in EC objects. The change propagations supported by EC objects enable designers to maintain the consistency of multiple product structure views for engineering, manufacturing or even customer support applications. This paper also includes EC examples and experimental implementations for the proposed EC objects.

• 지능정보연구
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• 제24권1호
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• pp.141-166
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• 2018

최근 디지털 인문학 (Digital humanities) 연구분야의 등장으로 정보기술을 활용하여 인문학 연구의 효율성 제고에 기여하고 있다. 특히 인문학 연구에서 특정한 인물 혹은 문서가 어떠한 사상 (idea)을 담고 있는지와 다른 사상과의 어떤 연결성을 가지는지를 자동적인 방법으로 분석하는 것은 지성사(intellectual history)를 파악하는 데 중요한 도전이 될 것이다. 본 연구의 목적은 책이나 논문, 기사와 같은 비정형 데이터 (unstructured data)에 포함된 주장을 파악하고 이를 다른 주장이나 사상과 어떠한 관련이 있는지를 자동으로 분석하는 방법을 제안하는 것이다. 특히 본 연구에서는 주장과 주장 사이의 영향관계를 밝히는 히스토리 마이닝 (History Mining)이라는 방법도 제안하였다. 이를 위해 딥러닝 기법 (deep learning method)을 포함한 분류알고리즘 기법 (classification algorithm)을 활용하였다. 본 연구가 제안하는 방법론의 성능을 검증하기 위하여 철학 사조 중에서 대표적으로 대비되는 경험주의와 합리주의 관련 철학자들을 선정하고 관련된 저서 혹은 인터넷 상의 글을 수집하였다. 분류 알고리즘의 성능은 Recall, Precision, F-Score 및 Elapsed Time으로 측정하였으며 DNN, Random Forest, 그리고 앙상블 등이 우수한 성능을 보였다. 선정된 분류 알고리즘으로 특정 철학자의 글에 대해 합리주의 혹은 경험주의로 분류하였으며, 그 철학자의 활동 연도를 고려하여 히스토리 맵을 생성할 수 있었다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권8호
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• pp.3465-3470
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• 2014

Background: Previous studies have generated conflicting evidence regarding associations between family history and survival after gastric cancer surgery. In this study, we investigated this question using a meta-analysis. Materials and Methods: To identify relevant studies, PubMed and Embase databases were searched up to June 2013. Two reviewers independently assessed search results and data extraction of included studies. Hazard ratios (HRs) and 95% confidence intervals (CIs) for overall survival (OS) were calculated based on fixed- or random-effects models. Homogeneity of effects across studies was assessed using $x^2$ test statistics and quantified by $I^2$. Results: A total of five studies were selected according to the inclusion criteria. The total number of patients included was 2,030, which ranged from 145 to 598 per study. There was no significant difference in OS by family history of cancer (HR=0.83, 95%CIs=0.50-1.38), but subgroup analysis of patients with a first-degree family history of cancer (HR=0.74, 95%CIs=0.60-0.93) and gastric cancer family history (HR=0.56, 95%CIs=0.41-0.76) tended to show better OS in these patients. Conclusions: This meta-analysis suggests that a first-degree family history of cancer or gastric cancer family history is associated with better survival of gastric cancer patients after surgery, after a systematic review of five previous studies. These results can be applied by clinicians when counselling patients regarding their risk of death from gastric cancer. Further study is needed to investigate the underlying mechanism between family history and survival in gastric cancer patients.