• Title/Summary/Keyword: histopathologic lesion

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A Surgical Experience of Livedo Vasculitis: A Case Report (청피반성 혈관염의 수술적 치험 1례)

  • Choi, Won Seok;Park, Dae Hwan;Song, Chul Hong
    • Archives of Plastic Surgery
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    • v.33 no.5
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    • pp.666-668
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    • 2006
  • Purpose: Livedo vasculitis is recurrent painful ulceration of the feet, ankles and legs characterized by purpuric papules and plaques that undergo superficial necrosis and healing with residual white atrophic scars (atrophie blanche). The typical histopathologic findings of livedo vasculitis are characterized by endothelial proliferation and hyaline degeneration along with thrombosis of dermal vessels. Standard therapeutic strategies for treatment of livedo vasculitis are usually on the basis of rheologic, anti-inflammatory or immnosuppressive treatments, a aspirin, dipyridamole, glucocorticosteroids, pentoxyfylline, or high-dose intravenous immunoglobulin are often ineffective or partially effective. Methods: We report a case of 24-year-old male patient with livedo vasculitis on the ankles and dorsal surfaces of both feet. Results: The lesion that had been unresponsive to medical treatment were successfully healed with complete debridement and skin grafting without recurrences. Conclusion: Surgical treatment can be one of the therapeutic choice in Livedo vasculitis.

Synovial Sarcoma Misunderstanding as a Benign Soft Tissue Tumor Finding on Ultrasonography (초음파에서 양성 연부조직 종양으로 오인된 활막육종)

  • Min, Kyoung-Dae;Hwang, Seok-Ha;Kim, Wook-Joong;Park, Sang-Mo;Lee, Byung-Ill
    • The Journal of Korean Orthopaedic Ultrasound Society
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    • v.5 no.1
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    • pp.22-26
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    • 2012
  • Ultrasonography is an effective first-line examination for soft-tissue masses. We reported a case who presented with superficial soft-tissue mass on the left distal thigh accompanying by pain. On ultrasonography, the lesion was determined as a benign mass. The patient, however, was diagnosed with synovial sarcoma based on the histopathologic result. Herein, we reported the case and reviewed of relevant literature.

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Histopathologic Lesion of Mannheimia haemolytica pneumonia in calves (송아지에서 발생한 Mannheimia haemolytica 폐렴의 병리조직학적 소견)

  • Jean, Young Hwa;Roh, In Soon;Lee, Kyung Hyun;Lee, Kyung Woo;Lee, Hee Soo
    • Korean Journal of Veterinary Research
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    • v.48 no.3
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    • pp.317-321
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    • 2008
  • Four 5 month old calves were died after showing respiratory distress after long-distance transportation at winter season. They were diagnosed as fibrinous lobar pneumonia caused by Mannheimia (M.) haemolytica. Grossly, lungs were attached onto the pleura by fibrin, with a rich yellowish fluid in thorax. The cut surface of the lung was showed marbled pattern of the reddish or greyish consolidation and widened interlobular septa by fibrin deposition. Histopathologically, parenchymal necrosis was delineated by a band of the degenerated inflammatory cells, and distended interlobular septa with serofibrinous exudates and vascular thrombosis with alveolar capillaries degeneration and abundant serofibrinous exudates in alveoli. M. hemolytica were isolated from all calves, and bovine viral diarrhea virus and parainfluenza type 3 virus in one calf were detected by RT-PCR. Thus, it was concluded that this case was diagnosed as pneumonic mannheimiosis suggested by complex infection with viruses after long-distance transportation and coldness.

THE IMPORTANCE OF THE PROPHYLACTIC NECK DISSECTION IN THE EARLY-STAGE TONGUE CANCER (초기설암치료시 예방적 경부곽청술의 의의)

  • Hong, Chang-Soo;Kim, Chin-Soo;Jang, Hyun-Joong;Lee, Sang-Han
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.17 no.1
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    • pp.73-81
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    • 1995
  • The poor survival rates of patients with carcinoma of a tongue, despite of modern therapy, is well recognized. One of the most important prognostic factors is status of the cervical lymph nodes. There have been a long-standing debate about the treatment of cervical lymph nodes in early-stage tongue cancer. There are two major treatment opinion. The one is surgical excision of primary tumor with prophylactic neck dissection, simultaneously, and the other is to delay the cervical therapy until cervical lymph node is palpable. Recently we have experienced the early cervical metastasis in three patients who had been diagnosed as a carcinoma of the tongue. They were T1, T2 lesion and no palpable node was found. But histopathologic examination showed the occult metastasis or delayed cervical metastasis was occured. By the review of literature and clinical experience, we could conclude the prophylactic neck dissection offers a better chance for success than therapeutic neck dissection of palpable lymph nodes, in case of oral tongue cancer.

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Salivary Gland Tumors: A Clinicopathologic Study of 366 Cases in Southern Iran

  • Jaafari-Ashkavandi, Zohreh;Ashraf, Mohammad-Javad;Moshaverinia, Maryam
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.1
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    • pp.27-30
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    • 2013
  • Background: Salivary gland tumors (SGT) are one of the most complex human neoplasms, demonstrating variations in their clinicopathological profile related to racial and geographic differences. Few studies with large samples have been reported in Iran. We here investigated a large group of patients in southern Iran. Materials and Methods: In this retrospective study, all cases of primary epithelial salivary gland tumors, which had been recorded in a 5 years period from 2005-2009, were enrolled. Clinical data such as histopathologic type and site of the lesion as well as patients' age and gender were analyzed. Results: Data of 366 cases of SGTs were recorded. Pleomorphic adenoma (80.2%) and adenoid cystic carcinoma (46.6%) were the most common benign and malignant neoplasms. Male to female ratio (M/F) and the mean age of patients were 1:1.05 and 37.7 for benign tumors while they were 1.2:1 and 50.6 for malignant tumors, respectively. Parotid and minor salivary glands were involved more frequently. Conclusions: Although the salivary gland tumours encountered were similar in most of their characteristics to those reported in other countries, some differences such as relative frequency and age and gender prevalence were discovered. These findings should help surgeons and pathologists for more accurate diagnosis, management and treatment.

Cherubism: Review of 2 Cases (체루비즘: 2예 보고)

  • Kwak, Juhee;Kim, Ji-Youn;Kim, Myung-Rae;Kim, Sun-Jong
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.34 no.5
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    • pp.357-362
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    • 2012
  • Cherubism is a rare familial disease of childhood, characterized by proliferative lesion, which is within the maxilla and mandible. In a typical case, painless symmetric expansile lesions develop in the jaws. It shows substitution of the bone by proliferating fibrous tissue exhibiting mature fibroblasts and a number of multinucleated giant cells within an intercellular matrix. Usually, the disease manifests in early childhood, and becomes more marked until puberty, at which time the bony lesions begin to regress. As such, conservative approaches to management are advisable. However, excision of tissue through enucleation or curettage appears to be necessary in more aggressive cases, to reduce the maxillofacial deformity after puberty and to ensure a successful outcome without the risk of progression, requiring additional resection. This report describes 2 cases of manifestation of cherubism of oral and maxillofacial region. We present diagnosis, radiological - histopathologic features, and treatment of cherubism.

FLORID OSSEOUS DYSPLASIA OF THE JAWS (상, 하악골에 발생된 개화성골이형성증)

  • Cho Su-Beom;Koh Kwang-Joon
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.25 no.1
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    • pp.159-170
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    • 1995
  • Few cases of florid osseous dysplasia has been described as a condition that characteristically affects the jaws. It usually manifests as multiple radiopaque masses distributed throughout the jaws. Confusion exists about the relationship of florid osseous dysplasia, gigantiform cementoma, chronic sclersing osteomyelitis, sclerosing osteitis or multiple enostosis. Authors experienced a case of florid osseous dysplasia of the jaws in 52-year-old female on the basis of clinical, radiographic and histopathologic findings. The characteristic features are as follows : 1. In clinical examination, there was no clinical sign and symptoms except extracted area. And there was no facial asymmetry. 2. Radiograms show round or lobular dense radiopaque masses surrounded by radiolucent bands in lower molar teeth area bilaterally. And slight increased radiopacities in maxillary molar teeth area bilaterally. There was no expansion or thinning of buccal and lingual cortical bones. There is no displacement or resorption of involved teeth. In right side of mandible, mandibular canal is displaced inferiorly due to mass. 3. Photomicrograms show densely mineralized sclerotic acellular masses with empty lacunae. Pattern is suggestive of cementum, although it could be considered sclerotic bone. In the periphery, lesion consisting of moderately cellular fibrous tissue in which globular calcified products are deposited.

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Recurrent odontogenic keratocyst within the masticatory space (저작근 공간에서 재발된 치성각화낭)

  • Lim, Su-Yeon;Huh, Kyung-Hoe;Yi, Won-Jin;Choi, Hyun-Bae;Choi, Soon-Chul
    • Imaging Science in Dentistry
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    • v.38 no.2
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    • pp.117-120
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    • 2008
  • The odontogenic keratocyst (OKC) is a developmental odontogenic cyst typically occurring in the jaws. Since the first description of OKC was published in 1956, the lesion has been of particular interest because of its specific histopathologic features, high recurrence rate, and aggressive behavior. Recurrences most commonly arise within bone at the site of the original cyst. However, as lining cells may find their way into surrounding tissues either from implantation during surgery or from cortical perforation recurrences may arise at a distance from the original cyst. Here, we report a rare case of recurrent OKC which was first developed in mandible and recurred within the masticatory space.

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Primary Sinonasal Squamous Cell Carcinoma with Contralateral Lymph Node Metastasis (반대측 림프절 전이를 동반한 비강의 편평 세포암 1예)

  • Kim, Tae-Hoo;Heo, Chul-Young;Kim, Beom-Gyu;Park, Il-Seok;Kim, Yong-Bok
    • Korean Journal of Head & Neck Oncology
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    • v.25 no.2
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    • pp.163-167
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    • 2009
  • Sinonasal malignant tumors comprise less than 1% of all cancers and 3% of all malignant tumors of the head and neck, which explains a lack of large series addressing the clinical characteristics and management of these tumors. Neck node metastasis occurs in only about 7% to 15% of malignant tumors compared with other head and neck cancers. A 90-yr-old woman presented with left palpable neck mass and right nasal mass occupying nasal cavity. Fine needle aspiration biopsy of left neck mass results in metastatic squamous cell carcinoma(SCC). PET/CT shows intense FDG uptake in right nasal cavity with bone invasion. Histopathologic examination of excised lesion in the right nasal cavity revealed SCC. We report here on a primary sinonasal SCC with contralateral lymph node metastasis.

A Case of Mucinous Gland Adenomatoid Hamartoma Originated from Submental Space (이하공간에 발생한 점액선 선종양 과오종 1예)

  • Kim, Sang Wook;Lee, Sung Min;Lee, Kang Hyun;Park, Ki Joon;Park, Hae Sang
    • Korean Journal of Head & Neck Oncology
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    • v.35 no.2
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    • pp.61-65
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    • 2019
  • Hamartomas are non-neoplastic malformations or congenital errors of tissue development. Hamartoma is composed by an excessive growth of mature tissue present in wrong proportions and abnormal arrangements. The lesion usually presents as a submucosal mass with ill-defined margins. Hamartoma occurs in all areas of the body, especially in the liver, spleen, kidney and lung. However, hamartoma is very rare in the head and neck. Presenting symptoms of hamartoma are typically vague and nonspecific. Treatment of hamartomas consists of adequate surgical excision. We present a 59 year-old male patient who presented with submental swelling. Malignancy could not be ruled out with preoperative radiologic examination, so surgical excision was planned. The mass was excised with transcervical approach. Histopathologic examination has confirmed the mass as a mucinous gland adenomatoid hamartoma.