• Preventive Nutrition and Food Science
• /
• v.1 no.1
• /
• pp.93-98
• /
• 1996

Lipopretein(a)[Lp(a)] is a macromolecular complex found in human plasma that combines structural elements composed of LDL and apo(a), and that is associated with premature coronary heart disease and stroke. In this study, various samples which consisted of normal and abnormal LDL and LP(a) were selected for compar-ison. The above samples were incubated with copper in order to oxidize and to compare atheroma formation, in vitro and free radical formation of Lp(a) was decreased compared to purified LDl. And LDL or Lp(a) from a 40 year old donor was higher in the free radical formation than that fro, a 20 years old donor. In order to investigate the macrophage foam cell formation, oxidized LDL of Lp(a) was incubated with human monocyte derived macrophage(HMDM). Oxidized samples enhanced on acceptability f foam cell formation by HMDM were compared to the control group. Also, structural change of LDL and Lp(a) against oxidation times were found from HPLC mapping.

• Kyungpook Mathematical Journal
• /
• v.61 no.3
• /
• pp.591-612
• /
• 2021

In this paper, a uniformly convergent numerical scheme is designed for solving singularly perturbed reaction-diffusion problems. The problem is converted to an equivalent weak form and then a Galerkin finite element method is used on a piecewise uniform Shishkin mesh with linear basis functions. The convergence of the developed scheme is proved and it is shown to be almost fourth order uniformly convergent in the maximum norm. To exhibit the applicability of the scheme, model examples are considered and solved for different values of a singular perturbation parameter ε and mesh elements. The proposed scheme approximates the exact solution very well.

• Korean Journal of Fisheries and Aquatic Sciences
• /
• v.39 no.2
• /
• pp.106-117
• /
• 2006

We measured the concentrations of organic matter and metallic elements (Al, Fe, Cr, Mn, Ni, Cu, Zn, As, Cd, Pb and Hg) in the surface sediments of Masan Harbor (in the southern sea, Korea) to evaluate the geochemical characters of sediment and the pollutions by organic matter and metallic elements. The mean grain size of the surface sediments in the study area ranged from $5.6{\phi}$ to $7.8{\phi}$, indicating silt sediment. The water content of the surface sediments exceeded 60% except at some stations. The contents of ignition loss (IL), total organic carbon (TOC) and total nitrogen (TN) ranged from 7.2-14.3%, 1.2-3.2%, and 0.10-0.28%, respectively. Based on the C/N ratios, the organic matter in the surface sediments of Masan Harbor may originate from terrigenous sources including fluvial inputs (mainly sewage in urban areas). The chemical oxygen demand (COD) and acid volatile sulfide (AVS) ranged from $11.3-29.9\;mgO_2/g\;dry$ and 0.20-4.47 mgS/g dry, respectively, and low concentrations were observed near a shipping route. In addition, the concentrations of metallic elements showed large spatial variations in Masan Harbor and the distributions of metallic elements were also comparable to those of organic matter. This implies that the distributions of organic matter and metallic elements in the surface sediments of Masan Harbor are mainly controlled by biogenic matter and artificial action (mainly dredging). In addition, we calculated the enrichment facto. (EF) and geoaccumulation index (Igeo) in order to evaluate pollution by metallic elements. The enrichment of metallic elements relative to Al was three to eighteen times higher at the study sites, compared to levels in the Earth's crust except for Fe, Ni and Mn. In addition, the Igeo class indicated that the surface sediments in the study area were moderately to strongly polluted in terms of metallic elements.

• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.30 no.1 s.244
• /
• pp.18-25
• /
• 2006

The purpose of this research work is to demonstrate a successful application of hybrid-mixed formulation and nodeless degrees of freedom in developing a very accurate in-plane curved beam element for free vibration analysis. To resolve the numerical difficulties due to the spurious constraints, the present element, based on the Hellinger-Reissner variational principle and considering the effect of shear deformation, employed consistent stress parameters corresponding to cubic displacement polynomials with additional nodeless degrees. The stress parameters were eliminated by the stationary condition, and the nodeless degrees were condensed by Guyan Reduction. Several numerical examples indicated that the property of the mass matrix as well as that of the stiffness matrix have a great effect on the numerical performance. The element with consistent mass matrix produced best results on convergence and accuracy in the numerical analysis of Eigenvalue problems. Also, the higher-order mixed curved beam element showed a superior numerical behavior for the free vibration analyses.

• Proceedings of the Korean Environmental Health Society Conference
• /
• 2002.04a
• /
• pp.16-19
• /
• 2002

This study was carried out to establish the standardized analysis method in order to decide accurate concentrations of hazardous metals in the air. Acid decomposition method used usually was compared to microwave digestion method. Comparing results of tested background concentration in blank filter, we found that the magnitude of element concentration was Na, Ca, K, Mg, Al and Ba by order. The element concentrations of Glass fiber filter were higher than those of Quartz fiber filter, and the number of undetected components in Glass fiber filter was lower than that in Quartz fiber filter. Thus it is supposed that the concentration of background elements in Glass fiber filter was higher than those in Quartz fiber filter The extraction rate of microwave digestion method was superior to those of acid decomposition method during the test of blank filter as well as SRM of NIST. In case of the SRM of NIST, the average extraction efficiency of acid decomposition Method and microwave pretreatment is 53.8∼82.7％, 81.3∼97.1％, respectively. This result might be caused by the closed system of Microwave, which make outflow and loss of components less. Also microwave digestion method has other merits such as the minimization of time, reagents, and contamination. Furthermore, if the extraction condition, extraction time and used acids are optimized, the better results will be represented.

• Journal of The Korean Astronomical Society
• /
• v.35 no.4
• /
• pp.209-220
• /
• 2002

In order to increase the completeness of the investigations of stellar abundances, we can use spectrum synthesis method, new atomic data and observation of stellar spectra with resolution comparable to solar spectral atlases. We made a brief review of main problems of these three ways. We present new results of abundance determinations in the atmospheres of four stars. The first is the implementation of new atomic data to well known Przybylski's star. We show that the number of spectral lines, which can be identificated in the spectrum of this star, can be significantly higher. The second example is the investigation of $\zeta$ Cyg. We found the abundances of 51 elements in the atmosphere of this mild barium star. The third example is halo star HD221170. Our preliminary abundance pattern consists of 42 elements. The heaviest elements in this pattern are U and Th. The last star is the spectroscopic binary HD153720. The number of elements investigated in the spectra of components of this star is not large, but the results show that the components are Am-stars.

• Proceedings of the Korean Society for Applied Microbiology Conference
• /
• 2000.04a
• /
• pp.178-181
• /
• 2000

In order to develop the novel gene expression system, we introduced new control elements which could influence the foreign gene expression in animal cells. When the foreign genes are introduced into the genome of higher eukaryotic cells, the expressions from these integrated genes are often low and can vary greatly depending on the positions of the integration sites due to the complex nature of the chromatin structures (1). First we screened the various DNA sequence elements which can function as an insulator of gene expression from these position effects and can cooperate with the SV40 enhancer/promoter. Among the several DNA elements from the various sources, we identified the particular DNA element which confers the increased frequency of the positive colonies, assayed by the reporter gene from stable selections indicating significantly reduced position effects. This element also showed the several fold-increased expression level as well as the copy-number dependent expression with host cell specificity. Second we modified the transcription termination element where we introduced the specific terminator in combination with SV40 polyA signal. This modified terminator showed the increased efficiency and the level of the gene expression. By combining these two elements, we made the animal cell expression system and tested successfully for the recombinant protein productions of TGF ${\beta}$-soluble receptor, Antithrombin III, and single chain Pro-Urokinase. [Supported by grants from MOCIE]

• Journal of Digital Convergence
• /
• v.18 no.10
• /
• pp.389-396
• /
• 2020

The purpose of this study is to investigate the various perspectives that children can provide by utilizing specific physical spaces for play, and to study how to effectively apply them to surrounding spaces and environments. AHP was used to analyze the preferred elements for effectively designing a play area. The main keywords were derived through case studies of various domestic and foreign play space designs, and each keyword was grouped and a keyword of a higher concept was derived. The results of the comparison of 14 keywords that were finally drawn using AHP for each element were used to derive the priority for the preferred elements. As a result, preference was derived in the order of "Openness", "Safety", and "Diversity" in the morphological properties of the play space, and "Adventure", "Five senses elements", "Visual elements" and "Interactivity" in the content properties of the play space.

• The Korean Journal of Quaternary Research
• /
• v.7 no.1
• /
• pp.69-91
• /
• 1993

A total of 76 surface sediment samples, collected from the Korean west coast and the eastern Yellow Sea areas, were analyzed for their elemental composition in order to understand the geochemical characteristics of these deposits. The analyzed elements included 9 major elements (Al, Fe, Na, K, Mg, Ca, Ti, P, Mn), 8 minor elements (Sr, Ba, V, Cr, Co, Ni, Cu, Zn), organic carbon and calcium carbonate. Contents of most analyzed elements, excluding K and Ba, were generally low compared to those of average crust. Contents of most elements, except K and Ca, also correlated with sediment grain size, though the degree of relationship varied widely from one element to another. For fine-grained sediments, a distinction could be made between those in the central Yellow Sea and those in the Keum Estuary based on their characteristic elemental composition: the former were rich in Fe, Na, K, Mg, Ca and V, and the latter in Mn, Co and Ni. The element/aluminium ratios, on the other hand, showed that the central Yellow Sea muds were enriched in Fe, Mg, V, Ni, Cu and Zn and depleted in K, Mn, Ba and Sr relative to the mud located near the Korean Peninsula. Based on the analysis of these results, as well as of the influences of particular mineral phases or pollution effects, we could suggest geochemical criteria which can be used in distinguishing muds from the two different sources, the Keum River and the Yellow River: the former by the higher Mn content and the latter by the higher Mg and V contents, relative to each other.

• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.36 no.10
• /
• pp.1139-1146
• /
• 2012

An alternative approach for topology optimization of steady incompressible Navier-Stokes flow problems is presented by using P1 nonconforming finite elements. This study is the extended research of the earlier application of P1 nonconforming elements to topology optimization of Stokes problems. The advantages of the P1 nonconforming elements for topology optimization of incompressible materials based on locking-free property and linear shape functions are investigated if they are also valid in fluid equations with the inertia term. Compared with a mixed finite element formulation, the number of degrees of freedom of P1 nonconforming elements is reduced by using the discrete divergence-free property; the continuity equation of incompressible flow can be imposed by using the penalty method into the momentum equation. The effect of penalty parameters on the solution accuracy and proper bounds will be investigated. While nodes of most quadrilateral nonconforming elements are located at the midpoints of element edges and higher order shape functions are used, the present P1 nonconforming elements have P1, {1, x, y}, shape functions and vertex-wisely defined degrees of freedom. So its implentation is as simple as in the standard bilinear conforming elements. The effectiveness of the proposed formulation is verified by showing examples with various Reynolds numbers.