• 제목/요약/키워드: high-producer

검색결과 245건 처리시간 0.026초

참여 지분형 계약거래를 통한 양식산업 금융지원 연구 (Research on Financing the Aquaculture Industry through Participatory Equity Contracting)

  • 이화용;한병석;강형구
    • 수산경영론집
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    • 제54권4호
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    • pp.47-64
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    • 2023
  • The development potential of the aquaculture industry is very high, but there is no financial support for investment except for the government, policy funds, fishery funds, etc. Therefore, we would like to propose a contract transaction in the aquaculture industry. This refers to a forward contract between a producer (fish farmer) and a buyer (mainly a processor or marketer) that stipulates the production and supply of fish products at a predetermined price, but it also refers to an "equity participation type" contract in which both producers and buyers can participate. In other words, it is a model in which part of the fish farm is produced in a way that meets the conditions of the buyer, and part is produced by the producer. This study aims to establish the basic contract trading process. It provides an academic approach to prevent adverse selection and moral hazard due to information asymmetry. It also provides an idea to converge the aquaculture industry with the financial industry using Pecking Order theory. By doing so, we have made it possible for venture capitalists to invest with confidence and provided a process for investors to resolve their concerns, paving the way for the aquaculture industry and the financial industry to develop together.

Rapid Establishment of CHO Cell Lines Producing the Anti-Hepatocyte Growth Factor Antibody SFN68

  • Song, Seong-Won;Lee, Song-Jae;Kim, Chang-Young;Han, Byungryeul;Oh, Jong-Won
    • Journal of Microbiology and Biotechnology
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    • 제23권8호
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    • pp.1176-1184
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    • 2013
  • Anti-hepatocyte growth factor (anti-HGF) monoclonal antibodies (mAbs) are potential therapeutics against various cancers. Screening for high-producer clones is a time-consuming and complex process and is a major hurdle in the development of therapeutic mAbs. Here, we describe an efficient approach that allows the selection of high-producer Chinese hamster ovary (CHO) cell lines producing the novel anti-HGF mAb SFN68, which was generated previously by immunizing HGF bound to its receptor c-Met. We selected an SFN68-producing parental cell line via transfection of the dihydrofolate reductase-deficient CHO cell line DG44, which was preadapted to serum-free suspension culture, with an SFN68-expression vector. Subsequent gene amplification via multiple passages of the parental cell line in a methotrexate-containing medium over 4 weeks, followed by clonal isolation, enabled us to isolate two cell lines, 2F7 and 2H4, with 3-fold higher specific productivity. We also screened 72 different media formulated with diverse feed and basal media to develop a suboptimized medium. In the established suboptimized medium, the highest anti-HGF mAb yields of the 2F7 and 2H4 clones were 842 and 861 mg/l, respectively, which were about 10.5-fold higher than that of the parental cell line in a non-optimized basal medium. The selected CHO cell lines secreting high titers of SFN68 would be useful for the production of sufficient amounts of antibodies for efficacy evaluation in preclinical and early clinical studies.

고해상도 IKONOS 위성영상을 이용한 임상분류 (Classification of Forest Type Using High Resolution Imagery of Satellite IKONOS)

  • 정기현;이우균;이준학;김권혁;이승호
    • 대한원격탐사학회지
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    • 제17권3호
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    • pp.275-284
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    • 2001
  • 본 연구에서는 강원도 평창군 봉평면 일대의 지역에 대해 2000년 4월 24일에 수신된 IKONOS 위성영상을 이용하여 피복분류를 수행하였다. 피복분류는 임상분류에 중점을 두었으며, 분류에 적용한 분류항목(class)은 현지조사 및 영상을 통하여 상록침엽수, 낙엽송, 활엽수, 나지, 밭, 초지, 수역, 사토지역, 아스팔트지역의 9개로 나누었다. 영상분류는 최대우도법을 적용하여 감독분류를 수행하였다. 정확도는 검정지역에 대한 전체정확도, 생산자정확도, 사용자정확도, k의 항목에 대해 분류오차행렬표를 통하여 평가하였다. 분류 및 분석에는 ERDAS사의 Imagine 8.4와 Purdue 대학에서 개발한 Multispec 소프트웨어를 사용하였다. 분류 결과, 검정지역에 대한 정확도는 전체정확도 94.3%, 생산자정확도 77.0-99.9%, 사용자정확도 71.9-100%, k은 0.93이었다. 나지, 사토지역, 밭 등의 경우 다른 분류항목보다 분류의 정확도가 비교적 낮게 나타난 반면, 임상분류에 있어서는 기존의 중해상도(5-30m) 위성영상보다 향상된 분류결과를 보여주었다.

조영제 부작용에 대한 주의의무와 제조물책임 (The Precaution Duty and the Product Liability for Adverse Reactions to the Contrast Media)

  • 강영한
    • 대한방사선기술학회지:방사선기술과학
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    • 제30권4호
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    • pp.305-311
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    • 2007
  • 조영제는 영상검사를 위해 유용한 의약품이며 점차 그 사용량이 늘어나고 있지만, 불가항력적인 부작용이 발생한다. 부작용에 대비해서 작성하게 되는 조영제 사용 동의서는 의료기관에게는 유리하고 피검자에는 불리한 내용이 담겨져 있어, 동의서에 부작용이 발생할 수 있다는 것에 동의하였다고 하여 그에 대한 손해배상책임까지 면제된다고 볼 수는 없다. 또한 조영제를 사용하는 검사 시 검사자와 조영제제조자는 선량한 관리자의 주의의무, 예견의무, 결과회피의무를 다하여야 하며, 의무를 소홀히 하게 되면 민사상의 책임이 있다. 조영제는 생산, 제조, 유통과정에 결함이 생길 수 있기 때문에 조영제제조자는 의약품 결함으로 인해 손해가 발생된다면 제조물책임을 지게 된다. 결함은 제조물의 제조 설계 또는 표시 상의 결함이나 기타 통상적으로 기대할 수 있는 안전성이 결여되어 있는 것으로 정의하고 있다. 제조물책임이란 제조물의 결함으로 말미암아 그 제조물의 이용자 또는 제 3자가 생명 신체 또는 재산상 손해를 입었을 때 그 제조물의 제조자나 판매자에게 그 결함제조물로 인하여 입은 손해를 배상하도록 책임을 묻는 것을 말한다. 조영제 사용의 증가 추세에 따른 부작용 발생빈도가 높아질 개연성과 함께 피검자들의 건강권에 대한 권리 의식이 점차 강조되고 있는 현실을 감안한다면 이제는 그에 대한 법적 책임이 정리되어야 하고, 조영제제조자는 조영제 사고에 대비하여 자구적인 대처방안을 수립하거나, 조영제 제조단체 공동으로 제조물책임보험을 들도록 하는 방안이 마련되어야 할 것이다. 의료기관과 조영제 회사 간의 거래 계약 체결 시 조영제 부작용에 대한 내용을 포함함으로써 의료기관이나 검사 당사자의 조영제 부작용 법적 책임을 경감할 수 있을 것이다.

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대중문화의 유형과 디자인 기획 (Types of Popular culture and Design planning)

  • 전선자
    • 한국디자인학회:학술대회논문집
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    • 한국디자인학회 2000년도 추계 학술발표대회 논문집
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    • pp.88-89
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    • 2000
  • 대중문화의 용어는 독일어로서 '마스'(Uass)와 '쿨투어'(Kultur)의 복합어이다. '마스', '마센'(복수: 많은 정도를 의미함)이란 유럽사회에서 비귀족적이고 교육을 받지 못한 계층으로, 오늘날 중하 이하 계충의 사람들을 칭하는 말이다. '쿨투어'(문화라는 의미)는 영어의 '하이 컬처(high cultur) 즉 고급문화'로서 유럽사회의 교육을 잘 받은 엘리트 계층이 수용하는 미술, 음악, 문학 등과 상징적 산물인 건축의 실내외 장식, 조경 등을 가리킬 뿐만 아니라 이러한 문화예술의 애호가들인 교양인, 지식인의 감정이나 사고의 유형 등까지도 포함하는 말이다.(중략)

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Novel Electromagnetic Induction Eddy Current DPH based Continuous Pipeline Fluid Heating using Soft Switching PWM High Frequency Inverter

  • Nam, Jing-Rak
    • Journal of information and communication convergence engineering
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    • 제6권3호
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    • pp.305-309
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    • 2008
  • This paper presents an innovative prototype of a new conceptual electromagnetic induction eddy current based fluid heating appliance using voltage-fed quasi resonant zero voltage soft switching PWM high-frequency inverter using IGBTs, which can operate at a constant frequency variable power regulation scheme. The promising simple high efficient low noise inverter type electromagnetic induction eddy current based pipeline fluid heating appliance is proposed for saturated steam generator, superheated steam generator, hot water and hot air producer, metal catalyst heating for exhaust gas cleaning in engine. Under these technological backgrounds, a novel electromagnetic induction eddy current Dual Packs Heater(DPH) based pipeline fluid heating incorporates thin metal layer type package for continuous fluid heating appliances applying two types of voltage-fed quasi load resonant ZVS-PWM high frequency inverter. The unique features of a novel electromagnetic induction eddy current DPH based continuous pipeline fluid heating appliance is illustrated on the basis of simulation and discussed for the steady state operating characteristics and experimental results.

Utility AC Frequency to High Frequency AC Power Frequency Converter without Electrolytic Capacitor Link for Consumer Induction Heating Appliances

  • Sugimura, H.;Eid, A.;Lee, H.W.;Kwon, S.K.;Suh, K.Y.;Nakaoka, M.
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2005년도 제36회 하계학술대회 논문집 B
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    • pp.1364-1367
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    • 2005
  • In this paper, a novel prototype topology of soft switching PWM controlled high frequency AC power conversion circuit without DC voltage smoothing chemical capacitor filter link from the voltage grid of utility frequency AC power supply source with 60Hz-100V or 60Hz-200V is proposed and introduced for innovative consumer induction heating(IH) boiler applications as hot water producer, steamer and super heated vapor steamer.

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광양만 예비 영양류 모형 (A Preliminary Trophic Flow Model for Gwangyang Bay, Korea)

  • 강윤호
    • 한국수산과학회지
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    • 제38권3호
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    • pp.184-195
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    • 2005
  • A preliminary quantitative model of the trophic structure in Gwangyang bay, Korea was obtained using ECOPATH and data from relevant studies to date in the region. The model integrates and analyzes biomass, food spectrum, trophic interactions and the key trophic pathways of the system. The bay model comprises 9 groups of benthic primary producer, phytoplankton, zooplankton, benthos, bivalve, pelagic fish, demersal fish and piscivorous fish. The total system throughput was estimated at $2.4\;kgWW/m^2/yr$, including a consumption of $41\%$, exports of $9\%$, respiratory flows of $24\%$ and flows into detritus of $26\%$. All of which originate from primary producers measured at $52\%$ and detritus of $48\%$. The total biomass was seen to be high compared to the levels of Somme, Delaware, Chesapeake Bays and Seine Estuary. This seems to be possibly due to artificial bivalve aquaculture and overestimation of benthos and benthic primary producer groups. The deviation can be calibrated by neglecting aquaculture and decreasing the habitat area for the groups. The trophic network of the bay shows a low level of recycling and organization as indicated by Finn's cycling index $3.3\%$, Ascendancy $3.1\;kgC/m^2/yr$ bits, Capacity $5.1\;kgC/m^2/yr$ bits and Redundancy $2.2\;kgC/m^2/yr$ bits. A high relative ascendancy of $62\%$ and a low internal relative ascendancy of $18\%$ indicate the system is not fully organized and stable towards disturbances, depending upon external connections. Although the model should be continuously provided with field data and calibrated further in depth, this study is the first trophic model applied to the region. The model can be a useful tool to understand the ecosystem in a quantitative manner.

원예부문 연구 및 지도 사업의 투자효과 분석 (Returns to Investment on Research and Extension in Korean Horticulture)

  • 강경하;이민수;최영찬
    • 농촌지도와개발
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    • 제7권2호
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    • pp.257-277
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    • 2000
  • The objectives of this study are to investigate the relationship between the growth of the horticultural sector and horticultural research and extension and to examine the socioeconomic returns to investment on research and extension in Korean horticulture. Data for horticultural production values, producer price indices and research and extension budgets for horticultural sector from 1965 to 1998 are collected from various sources. Multi-variate time series analysis technique with vector auto-regression model and Akino-Hayami Formula were employed for the analysis. This study finds (1) horticultural production responds about seven years later to the horticultural research investment shock. the magnitude of the impacts increases to a peak in seventeen years from the initial expenditures and then declines slowly thereafter until twenty years. and this peak gives a tip that horticultural research impact lasts much longer than grain's or agriculture's: (2) the social surplus from research investment benefits more to the consumer rather than to the horticultural producer: (3) B/C ratios in horticultural research are quite high with the range of 9 to 55 from 1965 to 1998. but these have been decreased since the early 1990s: (4) the socioeconomic returns to horticultural research is quite high with 56 percents of internal rate of return. It remains to be analyzed returns to investment on extension in horticulture because of no statistic significance in this study.

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Fluid Heating System using High-Frequency Inverter Based on Electromagnetic Indirect Induction Heating

  • Kim Yong-Ju;Shin Dae Cheul;Kim Kee Hwan;Uchihori Y.;Kawamura Y.
    • 전력전자학회:학술대회논문집
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    • 전력전자학회 2001년도 Proceedings ICPE 01 2001 International Conference on Power Electronics
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    • pp.69-74
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    • 2001
  • In this Paper are described the indirect induction heated boiler and induction heated hot air producer using the voltage-fed series resonant high-frequency inverter which can operate in the frequency range from 20kHz to 50kHz. A specially designed induction heater, which is composed of laminated stainless assembly with many tiny holes and interconnected spot welding points between stainless plates, is inserted into the ceramic type vessel with external working coil. This working coil is connected to the inverter and turbulence fluid through this induction heater to moving fluid generates in the vessel. The operating performances of this unique appliance in next generation and its effectiveness are evaluated and discussed from a practical point of view.

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