• Safety and Health at Work
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• v.7 no.2
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• pp.111-119
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• 2016

Background: Shift work and/or sleep quality may affect health. We investigated whether shift work and sleep quality, separately and jointly, were associated with abnormal levels of triglycerides, total cholesterol (TC), and low-and high-density lipoprotein cholesterol in 360 police officers (27.5% women). Methods: Triglycerides, TC, and high-density lipoprotein were analyzed on the Abbott Architect; low-density lipoprotein was calculated. Shift work was assessed using City of Buffalo payroll work history records. Sleep quality (good, ${\leq}5$; intermediate, 6-8; poor, ${\geq}9$) was assessed using the Pittsburgh Sleep Quality Index questionnaire. A shift work + sleep quality variable was created: day plus good sleep; day plus poor sleep; afternoon/night plus good; and poor sleep quality. Mean values of lipid biomarkers were compared across categories of the exposures using analysis of variance/analysis of covariance. Results: Shift work was not significantly associated with lipids. However, as sleep quality worsened, mean levels of triglycerides and TC gradually increased but only among female officers (age- and race-adjusted p = 0.013 and 0.030, respectively). Age significantly modified the association between sleep quality and TC. Among officers ${\geq}40$ years old, those reporting poor sleep quality had a significantly higher mean level of TC ($202.9{\pm}3.7mg/dL$) compared with those reporting good sleep quality ($190.6{\pm}4.0mg/dL$) (gender- and race-adjusted p = 0.010). Female officers who worked the day shift and also reported good sleep quality had the lowest mean level of TC compared with women in the other three categories (p = 0.014). Conclusion: Sleep quality and its combined influence with shift work may play a role in the alteration of some lipid measures.

• Journal of Food Hygiene and Safety
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• v.29 no.4
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• pp.370-375
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• 2014

Cladosiphon okamuranus is edible brown algae cultured commercially and massively at Okinawa coast. Dietary fiber occupying most of C. okamuranus isn't digested and absorbed by digestive enzymes of human. But it is known to prevent and treat constipation as metabolic disease. This study was to investigate the effects of dietary fiber extracted from C. okamuranus on the damage of liver and the blood cholesterol level in the high fat diet-fed rats. The effects were measured by the levels of aspartate aminotransferase (ALT), alanine aminotransferase (AST), total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL) and high density lipoprotein (HDL) in sera. The levels of ALT, AST, TC, TG and LDL were significantly reduced in the C. okamuranus-treated group compared with the high fat diet group. But HDL level was markedly increased. The results showed that the dietary fiber extracts from C. okamuranus have the inhibitive effects of cholesterol biosynthesis in the high fat diet-fed rats.

• The Korea Journal of Herbology
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• v.36 no.6
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• pp.39-46
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• 2021

Objectives : AMP-activated protein kinase (AMPK) is a key metabolic regulator that reduces lipogenesis. AMPK is mainly activated via phosphorylation of liver kinase B (LKB) 1 under energy stress. Here, we highlighted the anti-obesity effect and underlying mechanism of Coix lacryma-jobi var. mayuen Stapf sprout water extract (CSW) sprout extract in connection with the LKB1/AMPK signaling pathway. Methods : C57BL/6 mice (20~25 g) fed HFD to induce obesity and at the same time administered CSW 100 mg/kg (CSWL; (CSWL; CSW low concentration) or CSW 200 mg/kg (CSWH; CSW high concentration) or Garcinia extract (Garcinia) 200 mg/kg orally for 6 weeks. Body weight and food intake were measured at the same time each day. After 6 weeks of CSW administration, liver tissue and serum were obtained through an autopsy. After the end of the experiment, biochemical analysis (triglycerides (TG), total cholesterol (TC), HDL-cholesterol, and LDL-cholesterol) was performed on the serum. And then, protein levels related to TG and TC synthesis were measured through western blot analysis in liver tissue. Results : As a result, serum TG, TC, and LDL-cholesterol levels were significantly increased in the control group and significantly decreased in the CSW administration group. On the other hand, the HDL-cholesterol level was increased in the CSW-administered group. And as a result of Western blot analysis, CSW significantly increased the phosphorylation of LKB1 & AMPK, and remarkably decreased the expression of factors related to TG and TC synthesis. Conclusions : Our findings suggest that CSW influences the TG and TC synthesis to positively affect HFD-induced obesity in C57BL/6 mice.

• Journal of Nuclear Fuel Cycle and Waste Technology
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• v.1 no.1
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• pp.49-55
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• 2013

To characterize quantitatively the transport of $^{99}Tc$ and the global fallout ($^{137}Cs$, $^{90}Sr$, and $^{239+240}Pu$) for soils in Korea, the transport parameters of a convective-dispersion model, apparent migration velocity, and apparent dispersion coefficient were estimated from the vertical depth profiles of the radionuclides in soils. The vertical profiles of $^{99}Tc$ were measured from a pot experiment for paddy soil that had been sampled from a rice-field around the Gyeongju radioactive waste repository in Korea, and the vertical depth distributions of the global fallout $^{137}Cs$, $^{90}Sr$, and $^{239+240}Pu$ were measured from the soil samples that were taken from local areas in Korea. The front edge of the $^{99}Tc$ profiles reached a depth of about 12 cm in 138 days, indicating a faster movement than the fallout radionuclides. A weak adsorption of $^{99}Tc$ on the soil particles by the formation of Tc(VII) and a high water infiltration velocity seemed to have controlled the migration of $^{99}Tc$. The apparent migration velocity and dispersion coefficient of $^{99}Tc$ for the disturbed paddy soil were 2.88 cm/y and 6.3 $cm^2/y$, respectively. The majority of the global fallout $^{137}Cs$, $^{90}Sr$, and $^{239+240}Pu$ were found in the top 20 cm of the soils even after a transport of about 30 years. The transport parameters for the global fallout radionuclides were 0.01-0.1cm/y ($^{137}Cs$), 0.09-0.13cm/y ($^{90}Sr$), and 0.09-0.18cm/y ($^{239+240}Pu$) for the apparent migration velocity: 0.21-1.09 $cm^2/y$ ($^{137}Cs$), 0.12-0.7$cm^2/y$ ($^{90}Sr$), and 0.09-0.36$cm^2/y$ ($^{239+240}Pu$) for the apparent dispersion coefficient.

• Journal of the Korean Society of Radiology
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• v.13 no.2
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• pp.297-303
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• 2019

The nuclear medicine department of a domestic medical institution uses $^{99m}TcI$, a radionuclide, from $^{99}Mo/^{99m}TcI$ Generator, to inject radioactive drugs into patients. Among the expired generators, imported from foreign countries, the medical institution implements its own disposal. Each medical institution shall satisfy the permitted in-house disposal concentration of radioactive wastes. The guidelines for self-disposal presented in Korea suggested that self-disposal can be performed 80 days after the generator is used. The purpose of these guidelines is to analyze them by comparing them with the data measured directly with the generator and to study if they are feasible. As a result, the generator with a capacity of 1,000 mCi has the longest half-life, and when tested with a high-radiation Mo(molybdenum) column, the number of days that are below the permitted concentration of body disposal with radioactive waste was 72 days and 71 days that were derived from direct column measurement. The results of the direct study confirmed that the guidelines for in-house disposal in Korea were reasonable, as there were 8 to 9 days of storage compared to the number of in-house disposal days provided in the guidelines.

• The Korean Journal of Nuclear Medicine
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• v.32 no.2
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• pp.161-167
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• 1998

Purpose: Segmental parenchymal excretion delay on Tc-99m DISIDA scan is caused by intrahepatic bile duct obstruction. However, the diagnostic value for intrahepatic bile duct obstruction is unknown. We conducted this study to assess the positive predictive value of segmental excretion delay for the diagnosis of intrahepatic bile duct obstruction, and additional benefit over other noninvasive radiologic studies. Materials and Methods: The study population consisted of 43 patients (48 scans) who showed segmental parenchymal excretion delay on Tc-99m DISIDA scan. The results of abdominal CT or ultrasonography, which was done within 1 month of Tc-99m DISIDA scan, were compared with scintigraphic findings. Results: The etiology of segmental parenchymal excretion delay was determined by ERC or PTC in 31 scans, and follow-up studies in 13 scans. No causes were identified in 4 scans. The positive predictive value of segmental parenchymal excretion delay for intrahepatic bile ductobstruction was 92% (44/48). On the other hand, 13% (5/38) of CT and 28% (5/18) of ultrasonography were normal. In 18% (7138) of CT and 17% (3/18) of ultrasonography, only intraheipatic bile duct dilatation was noted without any diagnostic findings of intrahepatic bile duct obstruction. Conclusion: Segmental parenchymal excretion delay on Tc-99m DISIDA scan had a high positive predictive value for the diagnosis of intrahepatic bile duct obstruction. Tc-99m DISIDA scan may be useful for the diagnosis of intrahepatic bile duct obstruction, especially in patients with nondiagnostic CT or ultrasonography. The diagnostic usefulness need to be confirmed by further prospective studies.

• Proceedings of the KIEE Conference
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• 2002.07b
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• pp.741-743
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• 2002

Some different types of joining between two parallel high Tc superconducting tapes were prepared and I-V characteristic curves were obtained at the atmosphere of liquid nitrogen. Resistances in joint parts were estimated from I-V curves. We selected the best jointing method among these methods and its resistance were obtained at 28K. The availability of this joint method for fabricating HTS field coils is discussed.

• Proceedings of the KIEE Conference
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• 1996.07a
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• pp.184-186
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• 1996

This paper is a study on the analysis of normal zone propagating velocity in high Tc superconductor. Steady-state solution is analyzed based upon the one-dimensional heat transfer equation. This model incorporates the temperature and magnetic field dependent superconductor properties. The analytical results indicate that the propagation velocity is not a linear function of operating current, magnetic field and temperature.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.30 no.4
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• pp.350-356
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• 1994

We have prepared superconducting Bi-Pb-Sr-Ca.Cu-O thin films by RF magnetron sputtering technique, on heated MgO(100) substrates. Sputtering was carried out in a mixture of argon and oxygen(10%) and the pressure was maintained at 5 mTorr during deposition. The substrate temperature was maintained $400^{\circ}C$ during deposition. The films sputtered were amorphous and insulating. All the films became superconducting by annealing, The films annealed at $880^{\circ}C$ for 30 minutes in air showed high-Tc phase with zero resistivity of 93K. These results indicate that the growth of the high-Tc phase is promoted by the presence of Pb at annealing temperature.

• Progress in Superconductivity and Cryogenics
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• v.6 no.1
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• pp.38-42
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• 2004

The cryogenic system for 6.6 kV/200 A inductive superconducting fault current limiter (SFCL) was developed at Yonsei university in 2003. The sub-cooled nitrogen cryogenic system could be applied to not only SFCL but also many other applied high-Tc superconducting (HTS) devices like superconducting motor, superconducting generator and superconducting magnetic energy storage (SMES). Generally, the cooling capacity of GM-cryocooler depends on the load temperature. Therefore it is necessary to perform the cooling capacity test at no load condition to calculate the exact cooling power and heat load of cryogenic system. In this research, the cooling capacity test of GM-cryocooler was executed and the heat load of developed cryogenic system was calculated. The long run operation test results of sub-cooled nitrogen cryogenic system were successful in pressure and temperature condition. Moreover, the design and fabrication method of cryogenic system were introduced and the test results were described.