• Title/Summary/Keyword: high way

Search Result 6,668, Processing Time 0.032 seconds

The Relaxant Effect of Propofol on Isolated Rat Intrapulmonary Arteries

  • Zhang, Guangyan;Cui, Jianxiu;Chen, Yijing;Ma, Jue
    • The Korean Journal of Physiology and Pharmacology
    • /
    • v.18 no.5
    • /
    • pp.377-381
    • /
    • 2014
  • Propofol is a widely used anesthetic. Many studies have shown that propofol has direct effects on blood vessels, but the precise mechanism is not fully understood. Secondary intrapulmonary artery rings from male rats were prepared and mounted in a Multi Myograph System. The following constrictors were used to induce contractions in isolated artery rings: high $K^+$ solution (60 mmol/L); U46619 solution (100 nmol/L); 5-hydroxytryptamine (5-HT; $3{\mu}mol/L$); or phenylephrine (Phe; $1{\mu}mol/L$). The relaxation effects of propofol were tested on high $K^+$ or U46619 precontracted rings. Propofol also was added to induce relaxation of rings preconstricted by U46619 after pretreatment with the nitric oxide synthase inhibitor $N^G$-nitro-L-arginine methyl ester (L-NAME). The effects of propofol on $Ca^{2+}$ influx via the L-type $Ca^{2+}$ channels were evaluated by examining contraction-dependent responses to $CaCl_2$ in the absence or presence of propofol (10 to $300{\mu}mol/L$). High $K^+$ solution and U46619 induced remarkable contractions of the rings, whereas contractions induced by 5-HT and Phe were weak. Propofol induced dose-dependent relaxation of artery rings precontracted by the high $K^+$ solution. Propofol also induced relaxation of rings precontracted by U46619 in an endothelium-independent way. Propofol at different concentrations significantly inhibited the $Ca^{2+}$-induced contractions of pulmonary rings exposed to high $K^+$-containing and $Ca^{2+}$-free solution in a dose-dependent manner. Propofol relaxed vessels precontracted by the high $K^+$ solution and U46619 in an endothelium-independent way. The mechanism for this effect may involve inhibition of calcium influx through voltage-operated calcium channels (VOCCs) and receptor-operated calcium channels (ROCCs).

A Basic study on the sea model test techniques for high speed Planing Boat (실 해상모형시험을 이용한 고속 활주정의 선형시험기법 기초연구)

  • Jang, Dong-Won;Park, Chung-Hwan;Jin, Song-Han
    • Journal of Navigation and Port Research
    • /
    • v.34 no.8
    • /
    • pp.623-628
    • /
    • 2010
  • High speed marine vehicle, such as semi-planing, planing craft have been developed recently. These ships paid attention to the resistance characteristics, especially in high speed region. Model test method is divided to two equipment greatly, first 'Towing tank', second 'C.W.C.'. It is difficult to estimate a resistance characteristics for high speed boat. because these are made for low speed ship. This paper suggests a new model test method and system. This is real sea model test and it's comprised of eight part. Firstly, This method is tested at C.W.C that is possible to using in real sea model tes using low speed boat modelt. And then, Real sea model test and CFD calculation are performed and compared with tow way used high speed boat model. It can be a good way to estimate a performance for high speed boat.

4-way Search Window for Improving The Memory Bandwidth of High-performance 2D PE Architecture in H.264 Motion Estimation (H.264 움직임추정에서 고속 2D PE 아키텍처의 메모리대역폭 개선을 위한 4-방향 검색윈도우)

  • Ko, Byung-Soo;Kong, Jin-Hyeung
    • Journal of the Institute of Electronics Engineers of Korea SD
    • /
    • v.46 no.6
    • /
    • pp.6-15
    • /
    • 2009
  • In this paper, a new 4-way search window is designed for the high-performance 2D PE architecture in H.264 Motion Estimation(ME) to improve the memory bandwidth. While existing 2D PE architectures reuse the overlapped data of adjacent search windows scanned in 1 or 3-way, the new window utilizes the overlapped data of adjacent search windows as well as adjacent multiple scanning (window) paths to enhance the reusage of retrieved search window data. In order to scan adjacent windows and multiple paths instead of single raster and zigzag scanning of adjacent windows, bidirectional row and column window scanning results in the 4-way(up. down, left, right) search window. The proposed 4-way search window could improve the reuse of overlapped window data to reduce the redundancy access factor by 3.1, though the 1/3-way search window redundantly requires $7.7{\sim}11$ times of data retrieval. Thus, the new 4-way search window scheme enhances the memory bandwidth by $70{\sim}58%$ compared with 1/3-way search window. The 2D PE architecture in H.264 ME for 4-way search window consists of $16{\times}16$ pe array. computing the absolute difference between current and reference frames, and $5{\times}16$ reusage array, storing the overlapped data of adjacent search windows and multiple scanning paths. The reference data could be loaded upward and downward into the new 2D PE depending on scanning direction, and the reusage array is combined with the pe array rotating left as well as right to utilize the overlapped data of adjacent multiple scan paths. In experiments, the new implementation of 4-way search window on Magnachip 0.18um could deal with the HD($1280{\times}720$) video of 1 reference frame, $48{\times}48$ search area and $16{\times}16$ macroblock by 30fps at 149.25MHz.

A Study on the Level of Perception to Internet Shopping′ Benefit - Risk in Relation to the Internet Searching Value Types of College Student Consumers (대학생소비자의 인터넷탐색가치유형과 인터넷쇼핑에 대한 혜택-위험 지각정도에 관한 연구)

  • 홍은실
    • Journal of the Korean Home Economics Association
    • /
    • v.40 no.2
    • /
    • pp.161-173
    • /
    • 2002
  • This study explored the Internet searching values(utilitarian searching value and hedonic searching value) of college student consumers, typed the Internet searching values to four types, and analysed the level of perception to Internet shopping' benefit-risk according to the Internet searching value types. The subjects were 361 college students. We used Cronbach'$\alpha$, multiple regression, one-way ANOVA, and Scheffe' test as statistical analysis. The results were summarized as follows : 1) According to the Internet searching values, college student consumers were classified into 4 types - high utilitarian/high hedonic type, high utilitarian/low hedonic type, low utilitarian/high hedonic type, and low utilitarian/low hedonic type. 2) Both high utilitarian/high hedonic type and low utilitarian/high hedonic type had high level of perception to Internet shopping' benefit-risk.

A Study on the Dynamic Characteristics of the Composite Boring Bar (복합재료 보링바의 동적 특성에 관한 연구)

  • 황희윤;김진국;이대길
    • Proceedings of the Korean Society For Composite Materials Conference
    • /
    • 2003.04a
    • /
    • pp.206-210
    • /
    • 2003
  • Machining of deep holes with conventional boring bars frequently induce chatter vibration because of their low dynamic stiffness which is defined as the product of static stiffness and damping of conventional boring bar materials. In addition, the specific stiffness ($E/{\rho}g$) of boring bars is more important than the static stiffness to increase the fundamental natural frequency of boring bars in high speed machining. Therefore, boring bar materials should have high static stiffness and high damping as well as high specific stiffness. The best way to meet requirements is to employ fiber reinforced composite materials for high speed boring bars because composite materials have high static stiffness, high damping and high specific stiffness compared to conventional boring bar materials. In this study, the dynamic characteristics of carbon fiber epoxy composite boring bars were investigated. From the metal cutting test, it was found that the chatter was not initiated up to the ratio of length to diameter of 10.7 at the rotating speed of 2,500 rpm.

  • PDF

Park, Se-dang's understanding of Zhuxi (박세당의 주희 이해)

  • Huh, Jong-eun
    • The Journal of Korean Philosophical History
    • /
    • no.43
    • /
    • pp.55-80
    • /
    • 2014
  • Park, Se-dang criticized or accepted Zhuxi's annotation with his own way of understanding Confucian classics. His way of understanding Zhuxi can explain through the motive of writing his book, sabyeonrok and his basic view of scripture interpretation in the book. He thought one can achieve learning from lower to upper level. That means it is good for one to study from text easy to reach and attain, grasp. But if one begin to study from text or contents hard to understand, that will make to lose the proper way or province to the value of learning. This is what Park, Se-dang's basic point of interpreting Confucian classics, called 'learning from lower to upper level.' Park, Se-dang gave high praise Cheng Hao and Cheng Yi and Zhuxi who recreated confucianism into world from darkness. He thought Cheng-Zhu school corrected confucian's ways of learning went wrong from Chinese Han. So we need to reconsider the assessment of his view as anti?post-Zhuxi. He also thought there were a lot of way to understand Confucian classics. He insisted Zhuxi's way of annotating Confucian classics was one of them, and so as his. He understood Zhuxi's thought in this way of thinking and his academic method of 'learning from lower to upper level.' Therefore to interpretate Confucian classics new way he criticised or accepted Zhuxi's way of annotating scripture though his own way of understanding Confucian classics and academic method of 'learning from lower to upper level.'

Analytical Evaluation of High Velocity Impact Resistance of Two-way RC Slab Reinforced with Steel Fiber and FRP Sheet (강섬유 및 FRP Sheet로 보강한 2방향 RC 슬래브의 고속 충격저항성능에 대한 해석적 평가)

  • Lee, Jin Young;Shin, Hyen Oh;Min, Kyeng Hwan;Yoon, Young Soo
    • Journal of the Korea institute for structural maintenance and inspection
    • /
    • v.17 no.3
    • /
    • pp.1-9
    • /
    • 2013
  • This paper presents high-velocity impact analysis of two-way RC slabs, including steel fibers and strengthening with fiber reinforced polymer (FRP) sheets for evaluating impact resistance. The analysis uses the LS-DYNA program, which is advanced in impact analysis. The present analysis was performed similarly to the high-velocity impact tests conducted by VTT, the technical research center of Finland, to verify the analysis results. High-velocity impact loads were applied to $2100{\times}2100{\times}250$ mm size two-way RC slab specimens, using a non-deformable steel projectile of 47.5kg mass and 134.9m/s velocity. In this research, extra impact analysis of material specimens was carried out to verify the material models used to the analysis. The elastic-plastic hydrodynamic model, concrete damage model and orthotropic elastic model were used to simulate the non-linear softening behavior of steel fiber reinforced concrete (SFRC), and material properties of normal concrete and FRP sheets, respectively. It is concluded that the suggested analysis technique has good reliability, and can be effectively applied in evaluating the effectiveness of reinforcing/retrofitting materials and techniques. Also, the Steel fiber and FRP sheet strengthening systems provided outstanding performance under high-velocity impact loads.

The Effect of Marketing Communication and Store Loyalty in Traditional Markets: Focusing on Shopping Value and Shopping Experience (마케팅 커뮤니케이션이 점포 충성도에 미치는 영향: 쇼핑가치와 전통시장 이용경험을 중심으로)

  • Song, Mu-Yeung;Yang, Hoe-Chang
    • Journal of Distribution Science
    • /
    • v.10 no.11
    • /
    • pp.71-77
    • /
    • 2012
  • Purpose - This study examined marketing communication in traditional markets by assessing consumers demonstrating brand loyalty through repeat purchases despite active marketing by competing brands hence, showing that the brand did not lose customers owing to communication. Specifically, this study examined the effects of marketing communication factors in traditional markets upon consumers' store loyalty and to determine consumers' practical and hedonic values, as moderating variables. Moreover, this study determined that both experienced and inexperienced consumers in traditional markets could similarly assess the market and examined the outcome of traditional market development as well as future strategies. Research design, data, methodology - To verify the relationship between marketing communication and store loyalty, and the moderating effects of shopping value, data were collected from 230 consumers in the Gyeonggi Province to test the theoretical model and its hypotheses. Although the field of distribution management typically uses two research methodologies, this study was conducted using empirical methodology. Specifically, analysis of variance and hierarchical regression analysis were used to test the hypotheses. Results - Consumers who had experienced the traditional market placed a greater emphasis on the physical environment or word-of-mouth marketing. Moreover, other factors apart from advertising had a significantly positive influence upon marketing communication sub-factors and store loyalty. Word-of-mouth marketing was found to be more important than other factors, therefore affirmative word-of-mouth marketing was considered important from various viewpoints. The study investigated the moderating effects of hedonic value and practical use value in the relationship between marketing communication sub-factors and store loyalty: The negative influence of publicity, physical environment, and word-of-mouth marketing was considered to be statistically significant. Conclusions - Consumers who made use of the traditional market did not think of the physical environment in an affirmative way, and consumers who did not make use of the traditional market perceived it as having a poor physical environment. However, consumers who engaged in word-of-mouth marketing experienced the traditional market in an affirmative way. Consumers who made use of the traditional market had significantly high hedonic value and/or practical use value, therefore future strategies should encourage consumers to make more use of the traditional market. Consumers who had experienced the traditional market demonstrated strong market loyalty. For consumers who did not make use of the traditional market, marketing communication was likely to influence store loyalty in a different manner from a practical perspective. In other words, marketing communication was needed to develop the traditional market, and consumers who did not make use of the traditional market should be given the opportunity to do so. Consumers having low hedonic values experienced high publicity to have high store loyalty, and consumers who experienced good facilities of the traditional market had high store loyalty (Nam & Jun, 2011). Consumers with low hedonic values as well as those with high hedonic values on the traditional market could have high store loyalty through affirmative word-of-mouth marketing.Therefore, various types of events and strategies were needed to enable consumers to experience the traditional market in an affirmative way.

  • PDF

A Case Study about PET/CT Collaboration Operation (PET/CT 공동운영에 대한 사례 연구)

  • Kim, Chang-Ho;Pyo, Sung-Jae
    • The Korean Journal of Nuclear Medicine Technology
    • /
    • v.14 no.2
    • /
    • pp.87-92
    • /
    • 2010
  • Purpose: In 2003, we decided to buy a PET/CT, at the time, it was the latest cancer diagnostic medical equipment. Equipment company was offered the marketing of collaboration operation because the highly cost of PET/CT. However, this hospital's choice was own purchase way. In this study we evaluated the collaboration operation way by post-mortem analysis to the current situation. Materials and Methods: From 2004 until 2008, five years, we investigate the revenue analysis the number of PET/CT cases about own purchase way and collaboration operation way according (ABC costing). Results: The year 2004, own purchase way is 4 billion 9 thousand 2 hundred million won in deficit, the collaboration operation way is 1 billion 1 thousand 7 hundred million won in deficit. The year 2005, own purchase way is 1 billion 5 hundred million won in deficit, collaboration operation way is 8 thousand 7 hundred million won in deficit. However, the year 2006, own purchase way is 5 billion 1thousand 3 hundred million won in surplus, collaboration operation way is 9 thousand 9 hundred million won in deficits. The year 2007 and 2008, revenue of own purchase way is more increased but the collaboration operation way is more decreased. From the year 2004 to 2008, subtotal of own purchase way is 10 billion 8 thousand 8 hundred won in surplus, sub-total of collaboration operation way is 6 billion 7 thousand million won in deficit. Conclusion: Own purchase way has been a big benefit occurs and to reflect the equipment price, the collaboration operation way became to deficit continues. In other words, the problem of collaboration operation way showed us. When you buy the high cost Equipment, consideration will be risk and economic analysis of variance, the appropriate of the initial investment cost, clinical diagnostic needs and etc.

  • PDF

Development of High Speed Machining Technology (고속절삭가공기술개발)

  • 이춘만;최치혁;정원지;정종윤;고태조;김태형
    • Proceedings of the Korean Society of Machine Tool Engineers Conference
    • /
    • 2002.04a
    • /
    • pp.266-272
    • /
    • 2002
  • High-speed machining is one of the most effective technology to improve productivity. Because of the high speed and hugh fried rate, high-speed machining can alive great advantages for the machining of dies and molds. This paper describes on the improvement of machining accuracy in high-speed machining. Depth of cut, feed rate and spindle revolution are control factors. The effect of the control factors on machining accuracy is discussed fur the results of surface roughness and machining error in Z-direction of the high speed machining.

  • PDF