• Title/Summary/Keyword: high gradient magnetic separation

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Development of novel magnetic filter for paramagnetic particles in high gradient magnetic separation

  • Nishijima, Shigehiro;Nomura, Naoki
    • Progress in Superconductivity and Cryogenics
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    • v.24 no.3
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    • pp.7-11
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    • 2022
  • We are conducting research and development of magnetic filters for magnetic separation targeting paramagnetic materials. In order to develop a new magnetic filter with a large magnetic gradient, stainless fiber (SUS430, 120 mm × 3 mm) with a triangular cross section was sintered with a high void ratio (~ 70%) and the magnetic filter (20 mm × 2 mm) was created. When this magnetic filter was used to perform magnetic separation of hematite (particle size 50 ㎛) under a maximum magnetic flux density of 1.49 T, high separation rates were obtained.

Magnetic Separation of FCC Equilibrium Catalyst by HGMS

  • Xiang, Fazhu;He, Pingbo;Chen, Jin
    • Proceedings of the IEEK Conference
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    • 2001.10a
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    • pp.770-775
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    • 2001
  • Effects of magnetic field and carrier gas velocity on the magnetic separation of FCC catalyst by a high gradient magnetic separator were studied. The activities of the equilibrium catalyst, the magnetic particles and the nonmagnetic particles were evaluated in a fixed bed microreactor The results showed that heavy metal contaminated catalyst can be selectively separated by means of high gradient magnetic separation at magnetic field 0.5T and carrier gas velocity 0.3m.s$^{-1}$ , and lightly metal contaminated catalyst retained high catalytic activity.

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Magnetic separation device for paramagnetic materials operated in a low magnetic field

  • Mishima, F.;Nomura, N.;Nishijima, S.
    • Progress in Superconductivity and Cryogenics
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    • v.24 no.3
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    • pp.19-23
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    • 2022
  • We have been developing a magnetic separation device that can be used in low magnetic fields for paramagnetic materials. Magnetic separation of paramagnetic particles with a small particle size is desired for volume reduction of contaminated soil in Fukushima or separation of iron scale from water supply system in power plants. However, the implementation of the system has been difficult due to the needed magnetic fields is high for paramagnetic materials. This is because there was a problem in installing such a magnet in the site. Therefore, we have developed a magnetic separation system that combines a selection tube and magnetic separation that can separate small sized paramagnetic particles in a low magnetic field. The selection tube is a technique for classifying the suspended particles by utilizing the phenomenon that the suspended particles come to rest when the gravity acting on the particles and the drag force are balanced when the suspension is flowed upward. In the balanced condition, they can be captured with even small magnetic forces. In this study, we calculated the particle size of paramagnetic particles trapped in a selection tube in a high gradient magnetic field. As a result, the combination of the selection tube and HGMS (High Gradient Magnetic Separation-system) can separate small sized paramagnetic particles under low magnetic field with high efficiency, and this paper shows its potential application.

Buffer-Optimized High Gradient Magnetic Separation: Target Cell Capture Efficiency is Predicted by Linear Bead-Capture Theory

  • Waseem, Shahid;Udomsangpetch, Rachanee;Bhakdi, Sebastian C.
    • Journal of Magnetics
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    • v.21 no.1
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    • pp.125-132
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    • 2016
  • High gradient magnetic separation (HGMS) is the most commonly used magnetic cell separation technique in biomedical science. However, parameters determining target cell capture efficiencies in HGMS are still not well understood. This limitation leads to loss of information and resources. The present study develops a bead-capture theory to predict capture efficiencies in HGMS. The theory is tested with CD3- and CD14-positive cells in combination with paramagnetic beads of different sizes and a generic immunomagnetic separation system. Data depict a linear relationship between normalized capture efficiency and the bead concentration. In addition, it is shown that key biological functions of target cells are not affected for all bead sizes and concentrations used. In summary, linear bead-capture theory predicts capture efficiency ($E_t$) in a highly significant manner.

Research and development of new magnetic filter for high gradient magnetic separation

  • Shigehiro Nishijima;Naoki Nomura;Fumihito Mishima
    • Progress in Superconductivity and Cryogenics
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    • v.25 no.3
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    • pp.1-6
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    • 2023
  • We have been developing a new magnetic filter so that small sized paramagnetic substances can be separated even in a low magnetic field (lower than 2T). The developed filter is a packed ferromagnetic filament with a triangular cross section. The filament has a diameter of 120 ㎛ and a length of 3 mm, and is mechanically packed with a volume ratio of 17.6%. Using this filter, a magnetic separation experiment of hematite was carried out using a superconducting magnet at the field of 2T. Similarly, magnetic separation was performed using a conventional magnetic filter. It became clear that the separation efficiency of newly developed filter is high as that of conventional mesh filter. The smaller sized hematite (<3 ㎛) could be separated though conventional mesh filter could not separate.

Basic study on high gradient magnetic separation of nano beads using superconducting magnet for antibody purification

  • Jeongtae Kim;Insung Park;Gwantae Kim;Myunghwan Sohn;Sanghoon Lee;Arim Byun;Jin-sil Choi;Taekyu Kim;Hongsoo Ha
    • Progress in Superconductivity and Cryogenics
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    • v.25 no.4
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    • pp.60-64
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    • 2023
  • The manufacturing process of antibody drugs comprises two main stages: the upstream process for antibody cultivation and the downstream process for antibody extraction. The domestic bio industry has excellent technology for the upstream process. However, it relies on the technology of foreign countries to execute downstream process such as affinity chromatography. Furthermore, there are no domestic companies capable of producing the equipment for affinity chromatography. High gradient magnetic separation technology using a high temperature superconducting magnet as a novel antibody separation and purification technology is introduced to substitute for the traditional technology of affinity chromatography. A specially designed magnetic filter was equipped in the bore of the superconducting magnet enabling the continuous magnetic separation of nano-sized paramagnetic beads that can be used as affinity magnetic nano beads for antibodies. To optimize the magnetic filter that captures superparamagnetic nanoparticles effectively, various shapes and materials were examined for the magnetic filter. The result of magnetic separation experiments show that the maximum separation and recovery ratio of superparamagnetic nanoparticles are 99.2 %, and 99.07 %, respectively under magnetic field (3 T) and flow rate (600 litter/hr).

Treatment of rolling cooling waste water by superconductor HGMS method (초전도 자기분리에 의한 냉연공정 폐수처리)

  • Kim, Tae-Hyung;Ha, Dong-Woo;Oh, Sang-Soo;Kim, Young-Hun;Ha, Tae-Wook
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2008.06a
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    • pp.295-295
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    • 2008
  • This study introduced waste water treatment method applied superconductor HGMS(High Gradient Magnetic Separation). HGMS method treat high efficient method for various waste water. we have surveyed superconducting magnetic separation technology and reviewed the status of related industries using applied superconductivity. We fabricated the prototypes of magnetic matrix filter consisting of stainless steel mesh, which is a core component in the magnetic separation system. In our basic preliminary experiment using HGMS, it was made clear that the fine para-magnetic particles in the rolling colling wasted water obtained from rolling process of POSCO can be separated with high efficiency.

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Content and Distribution of Transition Metals and Rare Earth Elements in Magnetically and Mechanically Separated Brown Coal Ash

  • Malikov, Sh.R.;Pikul, V.P.;Mukhamedshina, N.M.;Sandalov, V.N.;Kudiratov, S.;Ibragimova, E.M.
    • Journal of Magnetics
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    • v.18 no.3
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    • pp.365-369
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    • 2013
  • Coal ash is known to contain a noticeable amount of valuable elements, including transition metals and lanthanides. Therefore it is quite actual problem to extract them for metallurgy and other applications. This paper presents the results of high gradient magnetic and mechanical separation, microscopy, element analyses and optical spectroscopy of brown coal ash taken from the combustion camera and chimney-stalk of Angren thermal power station. The separated magnetic fraction was 3.4 wt.%, where the content of Fe in ferrospheres increased to 58 wt.%. The highest contents of Fe and rare earth elements were found in the fine fractions of $50-100{\mu}m$. Optical absorption spectroscopy of water solutions of the magnetic fractions revealed $Fe^{2+}$ and $Fe^{3+}$ ions in the ratio of ~1:1. The separated coal ash could be used for cleaning of technological liquid waste by means of the high gradient magnetic field.

Superconducting high gradient magnetic separation for magnetic substance at sludge powder of hot rolled coolant

  • Kwon, Jun-Mo;Ha, Dong-Woo;Kim, Tae-Hyung;Cho, Mun-Dak;Choi, Woo-Hyuk
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2009.06a
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    • pp.353-353
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    • 2009
  • It is an important task to construct a recycling society with a low damage on the environment in our century. Magnetic separation is expected to be applied for the industrial waste treatment as an important supporting technology. In the magnetic separation of dry condition, the cohesive force between particles is strong compared with that in the wet condition's magnetic separation. The use of high magnetic field by the superconducting magnet enhances the powder's magnetic substance capture ability of the magnetic separation. In this study, the POSCO's coolant sludge of hot rolled steel was used for the superconducting magnetic separation of dry condition. Cryo-cooled NB-Ti superconducting magnet with 100 mm room temperature bore and 600 mm of height was used for magnetic separator.

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Development of superconducting high gradient magnetic separation system for scale removal from feed-water in thermal power plant

  • Shibatani, Saori;Nakanishi, Motohiro;Mizuno, Nobumi;Mishima, Fumihito;Akiyama, Yoko;Okada, Hidehiko;Hirota, Noriyuki;Matsuura, Hideki;Maeda, Tatsumi;Shigemoto, Naoya;Nishijima, Shigehiro
    • Progress in Superconductivity and Cryogenics
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    • v.18 no.1
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    • pp.19-22
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    • 2016
  • A Superconducting High Gradient Magnetic Separation (HGMS) system is proposed for treatment of feed-water in thermal power plant [1]. This is a method to remove the iron scale from feed-water utilizing magnetic force. One of the issues for practical use of HGMS system is to extend continuous operation period. In this study, we designed the magnetic filters by particle trajectory simulation and HGMS experiments in order to solve this problem. As a result, the quantity of magnetite captured by each filter was equalized and filter blockage was prevented. A design method of the magnetic filter was proposed which is suitable for the long-term continuous scale removal in the feed-water system of the thermal power plant.