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The Effects in Metabolism and Adipose Tissue Inflammation Induced by the Massa Medicata Fermentata on Obese Type 2 Diabetes Mouse Model (신국(神麯) 투여가 비만형 제 2형 당뇨병 동물모델의 대사인자와 지방조직 염증반응에 미치는 영향)

  • Paik, Sun-Ho;Han, Su-Ryun;Kwon, Oh-Jun;Ahn, Young-Min;Ahn, Se-Young;Lee, Byung-Cheol
    • The Journal of Korean Medicine
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    • v.33 no.3
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    • pp.33-45
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    • 2012
  • Objectives: Recent data have revealed that the plasma concentration of inflammatory mediators is increased in the insulin-resistant states of obesity and type 2 diabetes. The purpose of this study was to investigate the antidiabetic and anti-obesity effect of Massa Medicata Fermentata on obese type 2 diabetes mice. Methods: In order to examine the effects of Massa Medicata Fermentata, obese type 2 diabetes mice induced by Surwit's high fat, high sucrose diet. Mice were divided into 4 groups of ND (normal diet), HFD (high fat and high sucrose diet), Met (high fat and high sucrose diet with metformin) and MMF (high fat and high sucrose diet with Massa Medicata Fermentata) and investigated over 8 weeks. Diabetic and obese clinical markers, including body weight, glucose level, lipid level, leptin concentration, epididymal fat pad and liver weights and adipose tissue macrophage (ATM) were determined. Results: Compared with the HFD group, body weight, fructosamine, triglyceride, epididymal fat pad weight and ATM were significantly reduced in the MMF group. Conclusions: From the above results, the intake of Massa Medicata Fermentata may be effective in anti-hyperglycemia and anti-obesity by the attenuation of glucose and lipid levels and also inflammation state. Massa Medicata Fermentata may be beneficial for controlling diabetes mellitus type 2 in humans.

Effect of Heat-treatment on Microstructure and Tensile Properties in Cast Alloy 718 (주조 합금 Alloy 718에서 미세조직과 인장특성에 미치는 열처리의 영향)

  • Do, Jeong-Hyeon;Kim, In-Soo;Choi, Baig-Gyu;Jung, Joong-Eun;Jung, In-Yong;Jo, Chang-Yong
    • Journal of Korea Foundry Society
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    • v.36 no.5
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    • pp.167-173
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    • 2016
  • The effect of various types of heat-treatment on the mechanical properties of cast Alloy 718 has been investigated. Cast Alloy 718 bars were subjected to 'standard heat-treatment'_(SHT), 'HIP (Hot Isostatic Pressing) heat-treatment'_(HHT), and 'HIP-simulated heat-treatment'_(HS). In the absence of long time high temperature heat-treatment, a small amount of Laves phase remained in the 'SHT' specimen, and needle shaped ${\delta}$ precipitated in the vicinity of the Laves phase. Due to the formation of the Laves and ${\delta}$ phases in the 'SHT' specimen, it exhibited lower tensile properties than those of the others_specimens. On the other hand, the Laves phase was completely dissolved into the matrix after 'HHT' and 'HS' treatments. It is known that isostatic pressure reduces the self-diffusion coefficient, because of the lower self-diffusivity under HIP conditions in the interdendritic region, Nb segregation and the high amount of ${\gamma}^{{\prime}{\prime}}$ precipitation that occurs. Due to the higher fraction of coarse ${\gamma}^{{\prime}{\prime}}$ phases, the 'HHT' treated Alloy 718 showed excellent tensile strength.

Tests and finite element analysis on the local buckling of 420 MPa steel equal angle columns under axial compression

  • Shi, G.;Liu, Z.;Ban, H.Y.;Zhang, Y.;Shi, Y.J.;Wang, Y.Q.
    • Steel and Composite Structures
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    • v.12 no.1
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    • pp.31-51
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    • 2012
  • Local buckling can be ignored for hot-rolled ordinary strength steel equal angle compression members, because the width-to-thickness ratios of the leg don't exceed the limit value. With the development of steel structures, Q420 high strength steel angles with the nominal yield strength of 420 MPa have begun to be widely used in China. Because of the high strength, the limit value of the width-to-thickness ratio becomes smaller than that of ordinary steel strength, which causes that the width-to-thickness ratios of some hot-rolled steel angle sections exceed the limit value. Consequently, local buckling must be considered for 420 MPa steel equal angles under axial compression. The existing research on the local buckling of high strength steel members under axial compression is briefly summarized, and it shows that there is lack of study on the local buckling of high strength steel equal angles under axial compression. Aiming at the local buckling of high strength steel angles, this paper conducts an axial compression experiment of 420MPa high strength steel equal angles, including 15 stub columns. The test results are compared with the corresponding design methods in ANSI/AISC 360-05 and Eurocode 3. Then a finite element model is developed to analyze the local buckling behavior of high strength steel equal angles under axial compression, and validated by the test results. Following the validation, a finite element parametric study is conducted to study the influences of a range of parameters, and the analysis results are compared with the design strengths by ANSI/AISC 360-05 and Eurocode 3.

Effects of the Temperament and Character on Depression, Anxiety, and Maternal-Fetal Attachment in High-Risk Pregnant Women (고위험 임산부의 기질과 성격이 임산부의 우울, 불안, 모-태아 애착에 미치는 영향)

  • Jung, Sang Hyup;Bae, Jin Gon;Jung, Sung Won;Kim, Min Kyung;Kim, Hee Cheol;Kim, Jung Bum
    • Anxiety and mood
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    • v.14 no.2
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    • pp.106-111
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    • 2018
  • Objective : High-risk pregnant women are exposed to the physical and emotional crisis associate with the condition of high-risk pregnancy, making these women emotionally unstable, exhibiting such conditions as depression and anxiety. The aim of this study was to examine what effects the temperament and character of high-risk pregnant women had on their depression, anxiety, and maternal-fetal attachment. Methods : A hundred and five high-risk pregnant women were recruited in the maternity ward of the Keimyung University medical center. All subjects were administered a sociodemographic and obstetric questionnaire, Temperament and Character Inventory, Beck Depression Inventory-II, State Trait Anxiety Inventory-State, and Maternal-Fetal Attachment Scale. Results : First, higher scores on the harm-avoidance scale and lower scores on the self-directedness scale were associated with higher depression scores. Second, higher scores on the harm-avoidance and reward-dependence scale were associated with higher anxiety scores. Lastly, higher scores on the cooperativeness scale were associated with higher maternal-fetal attachment scores. Conclusion : Temperament and character in high-risk pregnant women were associated with the degree of depression, anxiety, maternal-fetal attachment. Based on these findings, it is suggested that examining temperament and character in advance and screening for vulnerability in pregnant women can help to prevent emotional problems for high-risk pregnant women.

Dynamic Deformation Behavior of Aluminum Alloys Under High Strain Rate Compressive/Tensile Loading

  • Lee, Ouk-Sub;Kim, Guan-Hee;Kim, Myun-Soo;Hwang, Jai-Sug
    • Journal of Mechanical Science and Technology
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    • v.17 no.6
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    • pp.787-795
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    • 2003
  • Mechanical properties of the materials used for transportations and industrial machinery under high strain rate loading conditions such as seismic loading are required to provide appropriate safety assessment to these mechanical structures. The Split Hopkinson Pressure Bar (SHPB) technique with a special experimental apparatus can be used to obtain the material behavior under high strain rate loading conditions. In this paper, dynamic deformation behaviors of the aluminum alloys such as A12024-T4, A1606 IT-6 and A17075-T6 under both high strain rate compressive and tensile loading conditions are determined using the SHPB technique.

Rapidly Solidified Fe-6.5wt% Si Alloy Powders for High Frequency Use

  • Park, Seung-Dueg;Yang, Choong-Jin
    • Journal of Magnetics
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    • v.2 no.1
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    • pp.12-15
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    • 1997
  • Fe-(3∼6.5wt%) Si alloy powders having a high magnetic induction(Bs) and a low core loss value for high frequency use were obtained by an extractive melt spinning as well as a centrifugal atomization technique. Sintered core rings made by the rapidly solidified Fe-6.5wt% Si powders exhibited the high frequency magnetic properties : megnetic induction(B8) of 1.23 T, coercivity(Hc) of 0.12 Oe, relative permeability(${\mu}$a) of 6321, and core loss(W10/50) of 1.27 W/kg from the rings of 1.1 mm thick. The magnetic induction values were found to be almost identical to those of non-oriented Fe-6.5wt% Si steel sheet and double the value of 6.5wt% Si sheet prepared by the CVD technique. The high frequency core losses(W) up to 10 kHz(W10/10k) were measured to be competitive to those of grain-oriented Fe-6.5wt% Si steel sheet.

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Eddy Current Loss Analysis of the Permanent Magnet Brushless AC Motor (영구자석 브러시리스 AC 모터의 와전류 손실 특성해석)

  • Jang, S.M.;Cho, H.W.;Lee, S.H.;Jeong, Y.H.
    • Proceedings of the KIEE Conference
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    • 2002.07b
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    • pp.700-702
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    • 2002
  • High-speed brushless permanent magnet machines are good for compressor and aerospace applications, etc. since they are conductive to high efficiency, high power density, small size and low weight. This paper presents 3-phase permanent magnet brushless AC Motor designed for the high-speed drives. Especially, we predicted the inverter high frequency pulse width modulation (PWM) switching caused eddy current losses in a permanent magnet brushless dc motor.

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Comparator design using high speed Bipolar device (고속 Bipolar 소자를 이용한 comparator 설계)

  • Park Jin-Woo;Cho Jung-Ho;Gu Young Sea;An Chel
    • Proceedings of the IEEK Conference
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    • 2004.06b
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    • pp.351-354
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    • 2004
  • This thesis presents Bipolar transistor with SAVEN(Self-Aligned VErtical Nitride) structure as a high-speed device which is essential for high-speed system such as optical storage system or mobile communication system, and proposes 0.8${\mu}m$ BiCMOS Process which integrates LDD nMOS, LDD pMOS and SAVEN bipolar transistor into one-chip. The SPICE parameters of LDD nMOS, LDD pMOS and SAVEN Bipolar transistor are extracted, and comparator operating at 500MHz sampling frequency is designed with them. The small Parasitic capacitances of SAVEN bipolar transistor have a direct effect on decreasing recovery time and regeneration time, which is helpful to improve the speed of the comparator. Therefore the SAVEN bipolar transistor with high cutoff frequency is expected to be used in high-speed system.

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Repetitive Controller for High Power UPS System with Low Switching Frequency (낮은 스위칭 주파수를 갖는 대용량 무정전 전원장치를 위한 반복제어기)

  • Lee, Taeyeong;Cho, Younghoon;KIM, JISU;BYEON, YONGSEOP
    • Proceedings of the KIPE Conference
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    • 2016.07a
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    • pp.477-478
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    • 2016
  • This paper introduces a repetitive controller in low switching frequency applications. Generally, A high power UPS system has a high rated current. And the system usually consist of high power IGBT has a tail current. So the high power UPS system operates in low switching frequency because of this tail current. The repetitive controller improve THD of output voltage or current by reducing the steady state error. The effect of the repetitive controller is proved by simulations.

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