• Title/Summary/Keyword: heterogeneous group

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A Case of Infantile Hepatic Hemangioendothelioma Incidentally Detected during the Evaluation of Galactosemia (선천성 갈락토스혈증으로 오인된 신생아 간 내 혈관내피종 1례)

  • Lim, Ryoung-Kyoung;Byun, Shin-Yun;Park, Seong-Shik;Kim, Young-Don
    • Neonatal Medicine
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    • v.17 no.1
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    • pp.136-140
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    • 2010
  • Galactosemia is a group of inherited enzyme deficiencies characterized by increase in the blood galactose levels. This condition may be associated with deficiencies of galactose-1-phosphate uridyl transferase, galactokinase, or uridine diphosphate galactose-4-epimerase. However, the elevated galactose identified by neonatal screening tests has several other possible etiologies, including hepatic hemangioendothelioma, hepatic hemangioma, and patent ductus venosus with hypoplasia of the portal vein. We report a 13-day-old Korean male with hepatic hemangioendothelioma, which was incidentally detected during the evaluation for suspected galactosemia. Laboratory studies revealed that mildly elevated levels of galactose, galactose-1-phosphate and alpha- fetoprotein, at the time of admission, were graduallydecreased to the normal range over the 6 months of observation. Ultrasonography showed a well-defined heterogeneous hypoechoic mass in the liver, and magnetic resonance imaging study showed multiple enhanced mass lesions, which was compatible with the diagnosis of a hepatic hemangioendothelioma. Thus, hepatic imaging, especially ultrasonography, should be performed if neonatal screening suggests galactosemia.

The Application and Integration of an Improvement Technique for Layers of NETCONF (NETCONF 계층에 대한 개선 기법 적용 및 통합)

  • Lee, YangMin;Lee, JaeKee
    • Journal of KIISE
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    • v.43 no.2
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    • pp.256-268
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    • 2016
  • Modern networks consisting of various heterogeneous equipment are often installed in a distributed manner. Thus the NETCONF standard was established to manage networks centrally and efficiently. In this paper, we present a method that integrates each NETCONF layer into a single system based on the results of previous studies. In the RPC Layer, an asynchronous communication channel and parallel processes are possible using multi-threading. In the Operation Layer, operational efficiency is increased by using a data group with dependencies between the equipment configuration data and by improving the data structure, enabling efficiently processing of XML queries even with multiple managers. The data modeling techniques and grouping methods in the Content Layer are presented in detail for interoperability between the Operation Layer and the Content Layer. Finally, the GUI program was implemented and its implementation is reported. We performed an experiment comparing the improved NETCONF with the standard NETCONF to measure factors, such as query processing ratio, query processing speed, and CPU utilization. The improved NETCONF demonstrated excellent query processing ratio and query processing speed, whereas the standard NETCONF had excellent CPU utilization.

Screening of Quinone Reductase Inducers from Agricultural Byproducts Using Mouse Hepatoma Cell Line (Mouse hepatoma 세포를 이용한 농산부산물로부터 quinone reductase활성물질의 탐색)

  • Kim, Jong-Sang;Nam, Young-Jung;Kim, Joo-Won
    • Korean Journal of Food Science and Technology
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    • v.27 no.6
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    • pp.972-977
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    • 1995
  • The induction of phase II enzymes including quinone reductase [NAD(P)H dehydrogenase(quinone): NAD(P)H : (quinone acceptor) oxidoreductase, EC 1.6.99.2] is a major mechanism of whereby a large group of heterogeneous compounds prevent the toxic, mutagenic, and neoplastic effects of carcinogen. Using murine hepatoma cells(Hepalclc7 cells), quinone reductase(QR) inducers as the possible chemopreventive agents were screened from rice bran, wheat bran, soymilk residue, defatted soybean cake, defatted sesame and perilla residues. The 80% methanol extracts of defatted sesame and perilla residues induced quinone reductase significantly while the others did have little effect on the enzyme induction. Thin layer chromatography of the extracts showed that the fastest moving band(Rf=0.70) in the developing solvent of n-butanol : n-propanol : 2N ammonia(10 : 60 : 30) was responsible for the enzyme induction by the 80% methanol extracts of defatted sesame and perilla residues. Further identification of active component(s) is in progress.

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The Effect of Grouping by Extraversion and Introversion in Paired Think-Aloud Problem Solving Using Problem-Solving Strategy (문제 해결 전략을 사용하는 해결자.청취자 활동에서 내.외향성에 따른 소집단 구성의 효과)

  • Jeon, Kyung-Moon;Kang, Hun-Sik;Noh, Tae-Hee
    • Journal of The Korean Association For Science Education
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    • v.23 no.1
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    • pp.57-65
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    • 2003
  • In this study, the effects of grouping by extraversion and introversion in paired think-aloud problem solving using a four-stage problem-solving strategy emphasizing planning and checking stages were investigated. Prior to the instructions, the students' extraversion/introversion in three high school classes (N=87) were examined, and those classes were randomly assigned to the homogeneous, the heterogeneous, and the control groups. The test scores of the two treatment groups were significantly higher than those of the control group in the problem-solving ability. However, there were no significant differences in learning difficulty and self-efficacy. Although there were no significant differences between the scores of two treatment groups in the subcategories of the perception of treatment, the test scores of extroverts were significantly higher than those of introverts in the perception of performing listener's role, the preference to problem solving strategy, and the preference to paired think-aloud problem solving.

Quantitative Analysis of Grafted Methacrylate Groups by Michael Addition Reaction between Primary and Secondary Amino Groups on the Silica Nanoparticle Surface with 3-(Acryloyloxy)-2-Hydroxypropyl Methacrylate (실리카 나노 입자 표면에 결합된 1차 및 2차 아미노기와 3-(Acryloyloxy)-2-hydroxypropyl Methacrylate의 마이클 부가 반응에 의해 도입되는 메타크릴레이트기의 정량적 분석)

  • Lee, Sangmi;Ha, KiRyong
    • Polymer(Korea)
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    • v.39 no.2
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    • pp.300-310
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    • 2015
  • In this study, we modified silica nanoparticles with N-[3-(trimethoxysilyl)propyl]ethylenediamine (TPED) silane coupling agent, which has one primary and one secondary amino groups in a molecule, to introduce amino groups on the silica surface. After modification of silica, we used 3-(acryloyloxy)-2-hydroxypropyl methacrylate (AHM) to introduce methacrylate groups by Michael addition reaction. We found about 30% of N-H groups on the TPED modified silica surface reacted with acrylate groups of AHM compared to about 85% of reaction between N-H groups of pure TPED with acrylate groups of pure AHM. This lower degree of Michael addition reaction for heterogeneous reaction between N-H groups on the solid TPED modified silica and liquid AHM compared to homogeneous reaction between pure liquid TPED and pure liquid AHM may be caused by lower mobility of grafted amino groups of TPED moiety and higher steric hindrance caused by solid silica particles.

Chronic cerebral hypoperfusion and plasticity of the posterior cerebral artery following permanent bilateral common carotid artery occlusion

  • Cho, Kyung-Ok;Kim, Seul-Ki;Kim, Seong Yun
    • The Korean Journal of Physiology and Pharmacology
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    • v.21 no.6
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    • pp.643-650
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    • 2017
  • Vascular dementia (VaD) is a group of heterogeneous diseases with the common feature of cerebral hypoperfusion. To identify key factors contributing to VaD pathophysiology, we performed a detailed comparison of Wistar and Sprague-Dawley (SD) rats subjected to permanent bilateral common carotid artery occlusion (BCCAo). Eight-week old male Wistar and SD rats underwent BCCAo, followed by a reference memory test using a five-radial arm maze with tactile cues. Continuous monitoring of cerebral blood flow (CBF) was performed with a laser Doppler perfusion imaging (LDPI) system. A separate cohort of animals was sacrificed for evaluation of the brain vasculature and white matter damage after BCCAo. We found reference memory impairment in Wistar rats, but not in SD rats. Moreover, our LDPI system revealed that Wistar rats had significant hypoperfusion in the brain region supplied by the posterior cerebral artery (PCA). Furthermore, Wistar rats showed more profound CBF reduction in the forebrain region than did SD rats. Post-mortem analysis of brain vasculature demonstrated greater PCA plasticity at all time points after BCCAo in Wistar rats. Finally, we confirmed white matter rarefaction that was only observed in Wistar rats. Our studies show a comprehensive and dynamic CBF status after BCCAo in Wistar rats in addition to severe PCA dolichoectasia, which correlated well with white matter lesion and memory decline.

Simulation model of a multihomed node with WiMAX and WLAN (WiMAX - WLAN 멀티홈드 노드의 시뮬레이션 모델)

  • Zhang, Xiao-Lei;Wang, Ye;Ki, Jang-Geun;Lee, Kyu-Tae
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.10 no.3
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    • pp.111-119
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    • 2010
  • With the rapid progress of wireless technologies today, mobile terminals with multiple access interfaces are emerging. In recent years, WLAN (Wireless Local Area Networks) has become the premier choice for many homes and enterprises. WiMAX (Worldwide Interoperability for Microwave Access) has also emerged as the wireless standard that aims to deliver data over long distances. Therefore, it is important to explore efficient integration methods for delivering multimedia data between heterogeneous wireless networks. In this paper, we developed the simulation models and environments for the mobile multihomed node that has both WiMAX and WLAN interfaces and can move around in both networks by using mobile IP. In order to verify the developed models, we designed and constructed several simulation scenarios, e.g. movement in WiMAX/WLAN, group mobility, MANET, and nested MIP under the various traffic environments such as oneway or bothway UDP packets, FTP traffic, and voice with SIP protocol. The simulation results show that the developed models are useful for mobility studies in various integrated wireless networks.

Probability-based Deep Learning Clustering Model for the Collection of IoT Information (IoT 정보 수집을 위한 확률 기반의 딥러닝 클러스터링 모델)

  • Jeong, Yoon-Su
    • Journal of Digital Convergence
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    • v.18 no.3
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    • pp.189-194
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    • 2020
  • Recently, various clustering techniques have been studied to efficiently handle data generated by heterogeneous IoT devices. However, existing clustering techniques are not suitable for mobile IoT devices because they focus on statically dividing networks. This paper proposes a probabilistic deep learning-based dynamic clustering model for collecting and analyzing information on IoT devices using edge networks. The proposed model establishes a subnet by applying the frequency of the attribute values collected probabilistically to deep learning. The established subnets are used to group information extracted from seeds into hierarchical structures and improve the speed and accuracy of dynamic clustering for IoT devices. The performance evaluation results showed that the proposed model had an average 13.8 percent improvement in data processing time compared to the existing model, and the server's overhead was 10.5 percent lower on average than the existing model. The accuracy of extracting IoT information from servers has improved by 8.7% on average from previous models.

The Synthetic comparative analysis of cultural Acculturation mechanism from North Korean women Elite-class in South Korea (출신성분에 따른 탈북여성의 문화적응 기제에 관한 비교분석)

  • Kim, Yun-Na;Joo, K.P.
    • Journal of Digital Contents Society
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    • v.18 no.2
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    • pp.329-338
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    • 2017
  • This study aims to examine heterogeneous acculturation patterns of elite North Korean female defectors in South Korea. The study employed a synthetic comparative analysis. A series of in-depth interviews with 5 North Korean female defectors in South Korea were conducted. In addition, the research team implemented 20 open-ended surveys with other defectors. Through this study, we have found various types of cultural adaptation in the group of the elite North Korean women in South Korea. The study findings imply that it is imperative to establish national policies that support different types of North Korean defectors. Putting all North Koreans into one category might result in alienation and discrimination to some groups. Thus how the participants reframed their social identify in South Korea illuminates essential facets of human-right education, especially education for refugees and immigrants in different global and multi-cultural contexts.

DESIGN AND ANALYSIS OF RANDOMIZED CLINICAL TRIALS REQUIRING PROLONGED OBSERVATION OF EACH PATIENT I. INTRODUCTION AND DESIGN

  • Peto R.;Pike M.C.;Armitage P.;Breslow N.E.;Cox D.R.;Howard S.V.;Mantel N.;Mcpherson K.;Peto J.;Smith P.G.
    • 대한예방의학회:학술대회논문집
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    • 1994.02b
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    • pp.206-233
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    • 1994
  • The Medical Research Council has for some years encouraged collaborative clinical trials in leukaemia and other cancers, reporting the results in the medical literature. One unreported result which deserves such publication is the development of the expertise to design and analyse such trials. This report was prepared by a group of British and American statisticians, but it is intended for people without any statistical expertise. Part!, which appears in this issue, discusses the design of such trials; Part II, which will appear separately in the January 1977 issue of the Journal, gives full instructions for the statistical analysis of such trials by means of life tables and the logrank test, including a worked example, and discusses the interpretation of trial results, including brief reports of particular trials. Both parts of this report are relevant to all clinical trials which study time to death, and would be equally relevant to clinical trials which study time to other particular classes of untoward event: first stroke, perhaps, or first relapse, metastasis, disease recurrence, thrombosis, transplant rejection, or death from a particular cause. Part I, in this issue, collects together ideas that have mostly already appeared in the medical literature, but Part II, next month, is the first simple account yet published for non-statistical physicians of how to analyse efficiently data from clinical trials of survival duration. Such trials include the majority of all clinical trials of cancer therapy; in cancer trials, however, it may be preferable to use these statistical methods to study time to local recurrence of tumour, or to study time to detectable metastatic spread, in addition to studying total survival. Solid tumours can be staged at diagnosis; if this, or any other available information in some other disease is an important determinant of outcome, it can be used to make the overall logrank test for the whole heterogeneous trial population more sensitive, and more intuitively satisfactory, for it will then only be necessary to compare like with like, and not, by chance, Stage I with Stage III.

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