• Journal of Korean Medical classics
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• v.29 no.2
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• pp.203-212
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• 2016

Objectives : In order to infer the effect of blood-activating and stasis-dispelling herbs by the analysis of effect terms which have extracted and refined, based on five tastes. Methods : I extracted the effect terms and five tastes of blood-activating and stasis-dispelling herbs written in Herbology. Extracted effect terms was divided into single meaning term and was refined as typical term. After that, I sorted herbs according to the five tastes and find the most highly mentioned effect terms. And I infered each herb's effects based on the relationship between five tastes and most highly mentioned terms. Results & Conclusions : I extracted 5 tastes and 53 effect terms and refined it as 43 effect terms. As the result of analyzing the effect term based the tastes, blood-activating and stasis-dispelling herbs are usually have blood-activating and pain-relieving. The herbs that have the hot taste, have the effect of moving-qi, stasis-breaking and aggregation-dispersing. And I supposed new effects of 5 kinds of herbs among them. The herbs that have the sweet tastes, have the effect of stasis-dispelling. And I supposed new effects of 2 kinds of herbs among them by analyzing the relationship between the tastes and effect terms.

• Journal of Physiology & Pathology in Korean Medicine
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• v.27 no.5
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• pp.497-508
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• 2013

In addition to our previous study on the diseases and symptoms described in Juan Wooden Slips(居延漢簡), here we focused on therapeutics of Juan Wooden Slips, including herbal medicines, acupuncture, and moxibution. In Juan Wooden Slips, there are 36 species of medicinal herbs and 17 herbal prescriptions. Among the medicinal herbs, 75% of herbs were also used in Shanghanzabing-lun(傷寒雜病論). In terms of efficacy and therapeutic range of the medicinal herbs and prescriptions, Juan Wooden Slips is very similar to Shanghanzabing-lun. In addition, acupuncture were used as a combined with moxibution or herbal remedies similarly to Shanghanzabing-lun. Thus, we suggest that the medical thoughts and technologies shown in Juan Wooden Slips might influence on the establishment of Shanghanzabing-lun.

• CELLMED
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• v.6 no.1
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• pp.3.1-3.4
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• 2016

Consumption of herbal products from the medicinal plants contaminated with heavy metals can cause serious consequences on human health. This is a major concern for traditional and herbal medicine. The present study was carried out to analyze and quantify the levels of six potentially toxic heavy metals namely arsenic, lead, cadmium, mercury, chromium and nickel in ten important Indian medicinal herbs. The air dried raw herbs were processed by microwave assisted wet digestion and analyzed by using atomic absorption spectrophotometer equipped with graphite tube atomizer. Except the chromium content in three plants, all the levels of six heavy metals analyzed were found to be quite below the permissible limits in all the ten raw medicinal herbs analyzed. The present work implies that, regular and systematic screening of raw medicinal herbs is necessary to check the levels of the heavy metal contaminants before using them for consumption or preparation of herbal formulations so that the possible contamination cannot cumulate up to the finished products.

• Journal of Korean Medical classics
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• v.30 no.4
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• pp.69-82
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• 2017

Objective : This study was conducted to infer the effect of superficies-resolveing herbs by analyzing effect terms which have extracted and refined, based on four temperatures and five tastes. Method : Firstly, temperatures, tastes and effect terms were extracted from the 27 kinds of superficies-resolving herbs written in Herbology. Then, each effect terms was divided into single meaning term and refined as typical term, using the inclusive effect terms I established. After that, herbs were grouped by tastes and found the effect terms which are mentioned most frequently. And it could be supposed to be classified into each herb's new effects based on the relationship between properties and those effect terms. It is also inferred into new tastes from some herbs by analysing the representative effects group of each taste and finding which other tastes can be related to each herb's effect. Result & Conclusion : All the superficies-resolving herbs can have wind-dispelling effect and superficies-resolving effect, except Bulpleuri Radix. This herb is able to has just the wind-dispelling effect. And it's more appropriate to categorize Bulpleuri Radix to heat-clearing herb group than superficies-resolving herb group, considering its several, distinctly cold characteristics. Some effects are concentrated to wind-cold-dispersing herb group and others to wind-heat-dispersing herb group. Each tastes has its own representative effect group. And, according to its tastes' representative effect, some of herbs are reasonable to get new effect term. With not so feasible reason, 4 kinds of herbs are supposed to contain all of hot, bitter, and sweet tastes. Also It's needed to study much deeper whether Perillae Herba, Zingiberis Rhizoma Crudus and Elsholtziae Herba are belong to superficies-resolving herb group or to interior-warming or damp-dissolving aromatic herb group.

• Journal of Society of Preventive Korean Medicine
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• v.17 no.1
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• pp.1-11
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• 2013

Objectives : The aim of this research is to produce information by gathering up the data on the interaction between medicinal herbs which lie scattered in oriental medical books, and to provide people with easy access to the information by visualizing it. Methods : For this purpose, this study established the fundamental data by organizing the patterns of interaction into some kinds after selecting a part of Bonchogangmok(本草綱目) and extracting its text. In addition, in an effort to visualize the data, the study converted the data into 'net' file and visualized the interaction between medicinal herbs on Pajek. The visualization was done targeting a total of three patterns, such as 1 medicinal herb, 2 medicinal herbs, and 1 prescription. With the data on 'Chinese Lacquer(乾漆)' for 1 medicinal herb, data on 'Licorice(甘草)' and 'Chinese Lacquer(乾漆)' for 2 medicinal herbs, and data on 'Iijin-tang(二陳湯)' for prescription, the research conducted the analysis of the network using 'Kamada-Kawaii Algorithm' on Pajek. Results : As a result of the analysis, it was possible to see the meanings at a single glance as the scattered and fractional meanings were integrated with focus on medicinal herbs, but the increasing number of analyzed medicinal herbs tended to more and more complicate their relationships, thus, requiring additional work like filtering. Conclusions : Such results are fairly applicable in on-line database, and it is judged that if further research expands its scope to include systematic classification of medicinal herbs or cover other medical books than Bonchogangmok, it will create more objective, abundant information.

• Journal of Life Science
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• v.22 no.12
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• pp.1729-1739
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• 2012

The aim of this study was to evaluate the clinical efficacy and safety of fermented medicinal herbs. A search of the China National Knowledge Infrastructure (CNKI), PubMed databases and Korean Journal of Oriental Medicine in 2000-2011 located 11 randomized controlled trials (RCTs) that investigated the clinical efficacy of fermented medicinal herbs. Domestic RCTs reported clinical efficacy on improvement of immune responses and clinical safety on usage of fermented medicinal herbs in subjects suffering from cerebral hemodynamics. Countries other than Chinareported studies on the cause of esophageal cancer and on local inflammatory reactions. In China, studies were reported on the effectiveness of fermented medicinal herbs on scapulohumeral periarthritis of the stasis type, chronic superficial gastritis, dysuria induced by benign prostatic hyperplasia of deficiency of kidney yang, diabetic nephropathy, essential hypertension, and benign prostate hyperplasia. These results indicate that fermented medicinal herbs have obvious clinical effects in some diseases and no adverse reactions. Therefore, we need to initiate more fermentation research with useful bacteria, fungi, and mushrooms to produce fermented medicinal herbs. Both governments and research authorities should focus on research involving fermentation of medicinal herbs.

• The Journal of Korean Medicine
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• v.30 no.2
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• pp.79-87
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• 2009

Objective: This study assessed five respective herbs in Cheonggugamrosu (CGGRS) for ability to inhibit malodor in vitro. Methods: We used malodor modeling of the salivary sediment system. Incubation mixtures were prepared with sediment at 16.7% (v/v), amino acids (cysteine and tryptophan) at 6mM and either herb extract at 1% (w/v) or water as control. Mixtures were incubated at $37^{\circ}C$ and odor was monitored organoleptically and for volatile sulfur compounds with the Halimeter. Indole/skatole was determined by Kovac's colorimetric method. Results: Two of the herbs, Caryophilli Flos and Glycyrrhizae Radix, had inhibitory effect on malodor generation. Both of them significantly reduced VSC, organoleptic odor and indole/skatole formation (p<0.05). Conclusions: We found Caryophilli Flos and Glycyrrhizae Radix played a main role in CGGRS. Both herbs have potential as effective anti-malodor agents and this suggests they are worthy of further exploration.

• Journal of Sasang Constitutional Medicine
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• v.20 no.2
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• pp.11-20
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• 2008

1. Objectives The objective of this paper is to understand on treatment of in critical state patients based on the text book of Sasang Constitutional Medicine. We expect this study can be helpful in treating the critical state patients. 2. Methods The study is mainly based on the bibliographical research on the "Dongyisoosebowon" and on the "Principle of dosing for patient in critical state". 3. Results and conclusions Lee je-ma suggested a health scale which people can measure his health grade from a standard healthy state to severe diseases. We investigated the treatment of 'critical state' patients according to his scale. Lee je-ma also confirmed the standard dose of herbs and how to take herbs in compliance with the state which each patient in. We tried to find a rules of treating the critical state patients based on the text "Dongyisoosebowon" and we suggested brief principles in treating patients.

• The Journal of Korean Medicine
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• v.42 no.4
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• pp.120-132
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• 2021

Objectives: The prevalence of Parkinson's disease is on an upward trend along with an increase in the aging population but there is no available treatment that halts the progression of neurodegeneration. This study reports a numerical analysis on Donguibogam and suggests novel herbal drugs, which have never been researched before but found to be deemed effective in this study. Methods: Referring to 71 Korean medicine symptom terms that represent the symptoms of Parkinson's disease, 4170 prescriptions described in Donguibogam were classified into two groups based on whether their main effects were effective for Parkinson's disease or not. Comparing the two groups, the chi-square test was performed to select statistically significant herbs, while the t-test, Wilcoxon test, and descriptive statistics were performed to determine the appropriate dose. Results: One hundred and twenty-seven prescriptions effective for Parkinson's disease were identified. The chi-square test determined 17 herbs that are effective for symptomatic treatment. Among the medicinal herbs, the authors suggest Osterici seu Notopterygii Radix et Rhizoma, Ephedrae Herba, Aconiti Tuber, Myrrha, Sinomeni Caulis et Rhizoma, and Aconiti Kusnezoffii Tuber as herbal candidates that have never been studied for Parkinson's disease. Through the statistical tests, it was judged that the mean value of the dose of the entire prescription was the appropriate dose for each herb. Conclusions: Seventeen herbs were selected for Parkinson's disease and the appropriate daily dose were calculated. Furthermore, this study presented a new process that applies a statistical method to traditional medical literature and preselecting herbs deemed effective for specific diseases.

• The Journal of Pediatrics of Korean Medicine
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• v.17 no.1
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• pp.53-69
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• 2003

This study was designed to investigate prescriptions and herbs for treating coughing In childhood(小兒咳嗽) with oriental medical literature. The results were summarized as follows; 1. 182 prescriptions and 212 herbs were used for healing coughing in childhood. 2. There are 12 cases which has the same name of prescription with different elements. Applied prescriptions can be recorded according to the number as follows. They are Samsoeum(蔘蘇飮) and Jeonglyukhwan, Ageosan(阿膠散), Gamgiltang(甘桔湯), Keumbichosan(金沸草散), Sabaeksan(瀉白散), Gilgyungtang(桔梗湯), Mahwangtang(麻黃湯), Baekbyungja(白餠子), Baeksanghwan(白祥丸). Boeunhwan, Whagaesan(華盖散) respectively. 3. Applied herbs can be recorded according to the number as follows. They are (杏仁), Radix glycyrrhizae(甘草), Rhizoma zingiberis(生薑), Rhizoma pinelliae(半夏), Radix ginseng(人蔘) Platycodi radix(桔梗), Mori cortex(桑白皮).