• Journal of Preventive Medicine and Public Health
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• 제25권4호
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• pp.343-356
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• 1992

Authors studied the workers' knowledge about the health problems detected through the previous workers' periodic health examination, content of follow-up management ana actions taken for their health problem detected on previous health examination. From June to September 1992, workers' periodic health examination was peformed on workers employed in 10 companies located in 2 middle-sized Korean cities. A questionnaire survey was done far 150 workers who reported to have $D_2$ result of either hypertension or liver disorder at the previous workers' periodic health examination done in 1991. The results are as follows; 1. Of 160 workers who had $D_2$ result of either hypertension or liver disorder in previous examination one year before, only 85 workers(51.3%, 43 workers with hypertension, 38 workers with live disorder) responded that they have such disorders. The other 65 workers responded to questionnaire were all those with C results. Respondents' knowledge about their diagnoses was relatively precise (95.2% in hypertension group, 94.6% in liver disorder group) but knowledge about classification of diseases was poor. 2. The main efforts to solve the health problem nab self management (20 spells, 55.3%), visiting clinic or hospital(6 spells, 12.8%), use of herb medicine (2 spells, 4.3%) and use of drug store(2 spells, 4.3%) in hypertension group. In liver disorder group, 30 spells (71.4%) relied on self management,6 spells (14.3%) on hospital or clinic and 9 spells (21.4%) had no effort to improve the health problem. Content of self management was low salt diet, quit smoking, regular exercise and quit alcohol drinking in order. Avoidance of salt in diet was high in hypertension group and quitting alcohol drinking was high in liver disorder group. In those with self management, 80.7% of hypertension group and 83.3% of liver disorder group continued previous effort. Those, however, who utilized clinic or hospital, only 16.7% and 50.0% were still visiting hospital or clinic. 3. Fifty seven percent of hypertension group and 64.3% of liver disorder group was presently smoking,8.5% and 11.9% reduced smoking and 21.3% and 14.3% stopped smoking. Forty nine percent of hypertension group and 28.6% of liver disorder group was presently drinking. Reduced alcohol intake was reported in 29.8% and 40.5%, 12.8ole and 23.8% stopped alcohol drinking. Sixty six percent of hypertension group and 73.8% of liver disorder group did no regular exercise, but 12.8% and 11.9% of each group increased their physical exercise far last one year. Forty three percent of hypertension group and 38.l% of liver disorder group was overweight (defined by bodymass index greater or equal than 25). Reduced body Weight was reported in 17.2% and 16.7% of each group. Reduced dietary salt intake was high in hypertension group (51.5%). The study results suggest that follow-up management after workers' periodic health examination is not satisfactory. In order to improve this situation, adequate information on the result of the workers' periodic health examination should be distributed to each worker group with health education and counselling.

• 한국식품영양과학회지
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• 제37권11호
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• pp.1529-1533
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• 2008

한약재의 방사선 조사여부를 확인하기 위해 도라지와 오가피에 $0{\sim}10\;kGy$의 감마선을 조사하고 PSL, TL 및 ERS 특성을 비교 검토하였다. PSL을 측정한 결과 비 조사된 한약재에서 한계치($T_1$)인 700보다 낮은 photon count 값을 보이면서 negative로 판정되었고, 0.15 kGy 이상 조사구는 한계치($T_2$)인 5,000보다 높은 photon count 값을 나타내면서 positive로 표시되어 방사선 조사된 것을 확인할 수 있었다. 또한 시료로부터 mineral을 분리하여 TL의 glow curve와 TL ratio($TL_1/TL_2$)를 확인하였다. 방사선 조사가 되지 않은 도라지와 오가피는 TL ratio가 0.007 이하의 값을 나타내었으며, 조사구(1.0 kGy 이상)에서는 0.314 이상의 TL ratio를 나타내었다. 도라지와 오가피는 본 연구에서 설정한 TL ratio의 한계치 0.1보다 높은 수치를 나타내어 방사선 조사여부 확인이 가능하였다. ESR 측정을 통한 방사선 조사 한약재 검지에서는 cellulose 라디칼에서 유래된 특이한 라디칼 신호를 보여주었고, 이는 도라지 시료에서 더욱 뚜렷하게 확인할 수 있었다. 이상의 결과에서 PSL, TL 및 ESR 분석은 도라지와 오가피의 방사선 조사 여부 확인에 적합한 방법임을 확인할 수 있었다

• 한방재활의학과학회지
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• 제23권3호
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• pp.1-14
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• 2013

Objectives The object of this study was to observe the favorable anti-arthritic effects of Samki-eum ($s\bar{a}nq\grave{i}-y\check{i}n$) on Freund's complete adjuvant (FCA)-induced arthritic Wistar rats. Methods Rheumatoid arthritis was induced by intradermal injection of FCA, and 300, 150 or 750 mg/kg of Samki-eum ($s\bar{a}nq\grave{i}-y\check{i}n$) were orally administered once a day for 14 days from 14 days after FCA treatments, and 15 mg/kg of dexamethasone was intraperitoneally administered as reference drug in this experiment. All rats were sacrificed at 14 days after continuous oral treatment of Samki-eum ($s\bar{a}nq\grave{i}-y\check{i}n$) or intraperitoneal administration of dexamethasone, and changes on the body weight, knee circumferences, gross arthritis score, inflammatory tissue prostaglandin (PG) $E_2$ levels were monitored with cartilage collagen components and glucosaminoglycans compositions - chondroitin sulphate, heparan sulphate and hyaluronic acid in the present study. Results As results of FCA treatment, classic rheumatoid arthritis featuring dramatical decreases on the body weights, cartilage collagen contents and bone glucosaminoglycans-chondroitin sulphate, heparan sulphate and hyaluronic acid contents, with increases on the knee circumferences, gross arthritis scores and inflammatory tissue $PGE_2$ levels. However, these changes from FCA-induced rheumatoid arthritis were clearly reduced by treatment of dexamethasone and both two different dosages of Samki-eum ($s\bar{a}nq\grave{i}-y\check{i}n$) 300 and 150 mg/kg in the present study. Although FCA-induced arthritis were more favorably inhibited by treatment of dexamethasone 15 mg/kg as compared with Samki-eum ($s\bar{a}nq\grave{i}-y\check{i}n$) 300 mg/kg, marked decreases of body weights were detected in dexamethasone 15 mg/kg treated rats, and Samki-eum ($s\bar{a}nq\grave{i}-y\check{i}n$) 300 mg/kg showed similar preserve effects on the cartilage glucosaminoglycan compositions in this study. Conclusions The results obtained in this study suggest that over 300 and 150 mg/kg of Samki-eum ($s\bar{a}nq\grave{i}-y\check{i}n$) showed favorable anti-arthritic effects on the FCA-induced arthritis mediated by suppression of $PGE_2$, a inflammatory mediator. However, detail mechanism studies should be conduced in future with the screening of the biological active compounds in this herb. Although overall anti-inflammatory effects Samki-eum ($s\bar{a}nq\grave{i}-y\check{i}n$) 300 mg/kg were lowered than those of dexamethasone 15 mg/kg treated rats, Samki-eum ($s\bar{a}nq\grave{i}-y\check{i}n$) 300 mg/kg treated rats showed similar preserve effects on the cartilage glucosaminoglycan compositions in this experiment.

• 대한한의학회지
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• 제16권2호
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• pp.177-194
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• 1995

폐암(肺癌)의 치료법(治療法)에 대해 서의치료(西醫治療) 동의치료(東醫治療) 동서의(東西醫) 결합치료(結合治療)에 대해 최근문헌(最近文獻)을 중심(中心)으로 고찰(考察)해 본 결과(結果) 다음과 같은 결론(結論)을 얻었다. 1. 폐암(肺癌)의 서의치료법(西醫治療法)은 소세포암(小細胞癌)(SCLS)과 비소세포암(非小細胞癌)(NSCLS)으로 나누어 분기(分期) 및 증상(症狀)에 따라 수술치료(手術治療) 방사선치료(放射線治療) 화학치료(化學治療)를 단독(單獨)으로 또는 두가지 이상 복합(複合)해서 활용(活用)한다. 2. 폐암(肺癌)의 동의치료(東醫治療)는 초기(初期), 중기(中氣), 말기(末期)로 나누어 부정거사(扶正祛邪), 공보겸시(功補兼施), 기혈쌍보(氣血雙補)의 치법(治法)을 쓰거나 증상(症狀)에 따라 폐비기허형(肺脾氣虛型), 폐열음허형(肺熱陰虛型), 습담어조형(濕痰瘀阻型), 기혈어체형(氣血瘀滯型), 기음양허형(氣陰兩虛型)으로 분(分)하여 변증시치(辨證施治)하거나 혹은 단미(單味) 또는 복방(復方)으로 대증치료(對證治療)를 한다. 3. 폐암(肺癌)에 대(對)한 동서의결합치료(東西醫結合治療)를 함으로써 생존율(生存率)이나 생존(生存)의 질(質)에 있어서 현저(顯著)한 향상(向上)이 있는데 수술후(手術後) 동서결합치료(東西結合治療)는 수술후(手術後) 회복력(回復力)을 촉진(促進)시키고 생존율(生存率)을 높였다. 방사선치료(放射線治療)와의 결합치료(結合治療)는 방사선치료(放射線治療)에 의한 독부작용(毒副作用)을 감소(減少)시켜 치료효과(治療效果)를 높이고 생존율(生存率)을 높였다. 화학요법(化學療法)과 동의결합치료(東醫結合治療)는 화학요법(化學療法)의 독부작용(毒副作用)을 경감(輕減)시키고 생존(生存)의 질(質)과 생존율(生存率)을 높였다. 이상(以上)의 결과(結果)로 보아 폐암(肺癌)의 치료(治療)는 진단(診斷)에서부터 치료(治療)의 전과정(全過程)을 통(通)해서 서의치료(西醫治療)와 동의치료(東醫治療)를 결합(結合)하여 종합치료(綜合治療)를 하므로써 폐암(肺癌)의 치료효과(治療效果)를 높일 수 있는 새로운 치료법(治療法)으로 계속적인 연구(硏究)가 필요(必要)할 것으로 사료(思料)된다.

• 생명과학회지
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• 제24권8호
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• pp.851-859
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• 2014

본 연구에서는 1-chloro-2,4-dinitrobenzene (DNCB)에 의해 유도된 아토피성 피부염 마우스 모델에서 고삼, 감초 및 백선피 추출물과 그들 복합 추출물(GGB)의 항아토피 효능을 평가하였다. 아토피성 피부염의 병리학적 형태인 홍반, 귀부종, 부종, 각질과 상처는 복합 추출물 중 고삼, 감초 및 백선피 추출물이 3:1:1로 혼합된 GGB-1 처리군에서 다른 시료 처리군들에 비하여 유의적인 억제 효능을 나타내었다. 또한 면역 기관인 비장의 무게도 GGB-1 처리군에서 감소하였고, 간의 무게는 정상군과 시료 처리군의 값이 유사한 결과를 나타내었다. 아울러 GGB-1 처리군에서 비만 세포의 침윤이 감소되었으며, 혈청 중 IgE의 농도 역시 GGB-1 처리군에서 가장 낮은 값을 보였다. 비록 단일 한약재와 그들의 혼합물 처리군에서는 면역 사이토카인(IFN-${\gamma}$, IL- 1, 4, 5, 6, 13, $1{\beta}$, and TNF-${\alpha}$) 의 값이 유의적으로 감소되었으나, 여러 가지 결과들을 종합하여 볼 때 고삼, 감초 및 백선피 추출물이 3:1:1로 혼합된 복합 추출물인 GGB-1이 아토피성 피부염의 개선에 효과적인 약물로 판단된다.

• The Journal of Korean Physical Therapy
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• 제3권1호
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• pp.109-121
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• 1991

농촌지역 성인의 요통 유병율과 요통 치료형태를 조사하기 위하여 1991년 4월 1일부터 20일 까지 경상북도 안동군 서후면에 거주하고 있는 만 20세에서 59세 사이 남${\cdot}$여 주민 총 2,024명을 대상으로 가정방문하여 면담이 완료된 1,106명을 대상으로 분석하였다. 면담된 1,l06명 중 530명이 요통을 경험하여 기간 유병율이 $47.9\%$였는데 연령교정한 남자의 유병율은 $43.7\%$, 여자는 $52.3\%$로 남여간에 통계적으로 유의한 차이를 보였다(p<0.005). 요통환자들의 요통 경과양상은 재발성이 남여 각각 $57.0\%,\;55.2\%$로 가장 높았고, 만성이 $28.9\%,\;35.8\%$, 급성미 $14.1\%,\;9.0\%$였다. 요통원인은 '원인은 잘 모르겠으나 나이가 들면서' $48.1\%$, '일을많이 해서' $15.1\%$, '외부의 물리적 충격'이 $11.3\%$ 등이었다. 요통환자 가운데 요통으로 일상생활을 제대로 못하거나 누워서 생활하는 사람이 $2.5\%$, 1시간 이상서 있거나 걸을 수 없는 사람이 $12.5\%$나 되었다. 요통환자의 $56.6\%$는 요통진단을 받기 위해 의료기관을 이용한 적이 없었고 $31.3\%$ 는 병${\cdot}$의원을 이용하였다. 아무 진단을 받지 않은 이유는 '별로 심하지 않고 견딜만 해서'가 $75.7\%$였다. 요통 치료양상은 첫번째 치료로 약물치료와 물리치료를 받은 경우가 남여 각각 $34.1\%,\;36.3\%$였고, 두 번째 치료로는 한약을 제일 많이 이용했고, 세번째 치료로는 침술을 제일 많이 이용했다. 요통환자들의 $15.5\%$가 민속요법을 사용한 경험이 있는데 그 내용을 '익모초를 삶아서 즙을 마셨다'. '닭 삶은, 국물에 소주를 섞어 마셨다'는 등 35가지로 다양하였다. 본 연구결과로 요통이 농촌주민들에게 중요한 보건문제임을 알 수 있었고, 요통이 발생하여도 병${\cdot}$의원을 이용한 사람은 3분의 1밖에 되지 않았고, 비과학적인 치료법을 많이 사용하고 있음을 알 수 있었다. 따라서 합리적인 요통치료법에 관한 보건교육 실시와 비과학적인 민속요법의 모용과 남용으로 인한 부작용과 의료비의 낭비를 막기 위한 홍보활동이 요구된다.

• 제3의학
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• 제2권1호
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• pp.35-54
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• 1997

We tried to observe the features of ancient medical practice by analysing the records related to medicine in the book, ${\ulcorner}$the Historical Records of the Three Kingdom${\lrcorner}$ of which content includes the features of medicine in mythology, plague, delivery of twins, drugs, medical system, shamanism, constitutional medicine, psychiatry, forensic medicine, deformity, a spa, medical phrase, health and welfare work, religion, death. physiological anatomy, Taoist medicine, acupuncture, the occult af of transformation and etc. Our initial concern was about where to draw line as of medical field and we defined medicine in more broad meaning. The book ${\ulcorner}$the Historical Records of the Three Kingdoms${\lrcorner}$ describes the world of mythology by way of medicine which is not clearly a conventional one. There appears records of birth of multiple offsprings 7 times in which cases are of triplets or more. Delivering multiple offsprings were rare phenomenon though such fertility was highly admired. This shows one aspect of ancient country having more population meant more power of the nation. Of those medical records conveyed in that book includes stories of childbirth such as giving birth to a son after praying, giving birth to Kim Yoo-shin after 20 months after mother's dream of conception, and a song longing for getting a laudable child. Plagues were prevalent throughout winter to spring season and one can observe various symptoms of plagues in the record. Of these epidemic diseases, cold type might have been more common than the heat one. Appearance of epidemic diseases frequently coincided with that of natural disasters that this suggests a linkage between plague and underlying doctrine on five elements' motion and six kinds of natural factors. There exists only a few names of diseases such as epidemic disease, wind disease, and syndrome characterized by dyspnea. Otherwise there appeared only afflictions that were not specified therefore it remains cluless to keep track of certain diseases of prevalence. Since this ${\ulcorner}$Historical Records of the Three Kingdoms'${\lrcorner}$ wasn't any sort of medical book, words and terms used were not technical kind and most were the ones used generally among lay people. Therefore any mechanisms of the diseases were hardly mentioned. Some of medicinal substances such as Calculus Bovis, Radix Ginseng, Gaboderma Luciderm, magnetitum were also in use in those days. 53 kinds of dietary supplies appears in the records and some of these might have been used as medicinal purpose. Records concerning dicipline of one's body includes activities such as hunting, archery, horseback riding etc. In Shilla dynasty there were positions such as professor of medicine, Naekongbong(內供奉), Kongbong's doctor(供奉醫師), Kongbong's diviner(供奉卜師). As an educational facility, medical school was built at the first year of King Hyoso's reign and it's curricula included various subjects as ${\ulcorner}$Shin Nong's Herbal classic${\lrcorner}$, ${\ulcorner}$Kabeul classic of acupuncture and moxbustion${\lrcorner}$, ${\ulcorner}$The Plain Questions of the Yellow Emperor's Classic of Internal Medicine${\lrcorner}$, ${\ulcorner}$Classic of Acupuncturer${\lrcorner}$, ${\ulcorner}$The Pulse Classic${\lrcorner}$, ${\ulcorner}$Classic of Channels and Acupuncture Points${\lrcorner}$ and ${\ulcorner}$Difficult Classic${\lrcorner}$. There were 2 medical professors who were in charge of education. To establish pharmacopoeia, 2 Shaji(舍知), 6 Sha(史), 2 Jongshaji(從舍知) were appointed. In Baekje dynasty, Department of Herb was maintained. Doing praying for the sake of health, doing phrenology also can be extended to medical arena. Those who survived over 100 years of age appear 3 times in the record, while 98 appears once. The earliest psychiatrist Nokjin differentiated symptoms to apply either therapies using acupuncture and drug or psychotherapy. There appears a case of rape, a case of burying alive with the dead, 8 cases of suicide that can characterize a prototype of forensic medicine. Deformity-related records include phrases as follow: 'there seems protrudent bone behind the head', 'a body which has two heads, two trunks, four arms.', 'a body equipped with two heads' In those times spa can be said to be used as a place for he리ing, convalescence, and relaxation seeing the records describing a person pretended illness and went to spa to enjoy with his friends. Priest doctors and millitary surgeons were in charge of the medical sevice in the period of the Three Kingdoms by the record written by Mookhoja(墨胡子) and Hoonkyeom(訓謙). Poor diet and regimen makes people more vulnerable to diseases. So there existed charity services for those poor people who couldn't live with one's own capacity such as single parents, orphans, the aged people no one to take care and those who are ill. The cause of affliction was frequently coined with human relation. There appeared the phenomenon of releasing prisoners and allowing people to become priests at the time of king's suffering. Besides, as a healing procedure, sutra-chanting was peformed. There appears 10 cases of death related records which varies from death by drowning, or by freezing, death from animals, death from war, death from wightloss and killing oneself at the moment of spouse's death and etc. There also exist certain records which suggest the knowledge of physiology and anatomy in those times. Since the taoist books such as ${\ulcorner}$Book of the Way and Its Power(老子道德經)${\lrcorner}$ were introduced in the period of Three Kingdoms, it can be considered that medicine was also influenced by taoism. Records of higher level of acupuncture, records which links the medicine and occult art of transformation existed. Although limited, we could figure out the medical state of ancient society.