• Title/Summary/Keyword: hepartic

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Effects of Water Extracts of Red Pepper Seeds Powder on Antioxidative Enzyme Activities and Oxidative Damage in Rats Fed High-Fat and High-Cholesterol Diets (고추씨 물추출물이 고지방과 고콜레스테롤 식이 흰쥐의 항산화 효소활성 및 산화적 손상에 미치는 영향)

  • Kim, Yu-Na;Ku, Kyung-Hyung;Kang, Sin-Kwon;Choi, Jeong-Hwa
    • Journal of Nutrition and Health
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    • v.44 no.4
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    • pp.284-291
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    • 2011
  • The purpose of the present study was to examine the effects of water extracts from red pepper seeds powder on antioxidative enzyme activities and oxidative damage in groups of rrats fed high-fat and high-cholesterol diets group (HFC). The Rrats were divided into the following five experimental groups which are : composed of a normal diet group, a high fat high cholesterol diet group, and a high fat high cholesterol diet group supplemented with different amounts contents (1%, 2% and 4%) of red pepper seeds powder water extracts supplemented groups (HFCW1, HFCW2 and HFCW4, respectively). Body weight gains and food intake were lower ofin the red pepper seed water extracts groups were lower than those inof the HFC group. Hepartic xanthine oxidase (XOD) activity was decreased in the HFCW2 and HFCW4 groups compared to the HFC group. Hepartic glutathione peroxidase (GSH-px) activitiyactivity was increased in the HFCW4 group compared to the HFC group. Hepatic superoxide radicals within the mitochondria and microsomes of cells were significantly reduced in the HFCW2 and HFCW4 groups compared to the HFC group. Hepartic hydrogen peroxide in the cytosol was significantly reduced in the HFCW3 and HFCW4 groups compared to the HFC group. Hepatic carbonyl values in the microsomes and mitochondria were significantly reduced in the HFCW4 group compared to the HFC group. Hepartic thiobarbituric acid reaction substance (TBARS) activity was decreased in the HFCW2 group compared to the HFC group. These results suggest that water extracts of red pepper seeds powder may reduce oxidative damage by activation of antioxidative defense systems in rats fed high fat-high cholesterol diets.

PATHOLOGICAL STUDIES ON THE CHRONIC TOXICITY OF METHAMPHETAMINE ADMINISTRATION

  • Rim, Byung-Moo;Cho, Gye-Myung;Chang, Jae-Hong
    • Toxicological Research
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    • v.9 no.2
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    • pp.233-240
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    • 1993
  • Toxic effects of chronic adminstration of methamphetamine (MA) to SD rats were studied in respect to histopathological changes induced in each organ. In experimental groups liver weight decreased and brain weights increased markedly compared with controls in the 12th month after subcutaneous injection of 0.5 mg and 5mg/kg/BW MA. Serum alkaline phosphotase levels increased, but marked decrease of cholesterol, triglyceride, and BUN levels were checked depending on both the dose of MA and duration of treatment.

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A Report of Carcinus aestuarii (Decapoda: Brachyura: Carcinidae) from Korea

  • Lee, Sang-kyu;Lee, Sang-Hui;Kim, Hyun Kyong;Song, Sung Joon
    • Animal Systematics, Evolution and Diversity
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    • v.36 no.4
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    • pp.420-423
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    • 2020
  • As a result of continuous taxonomic studies on the Korean crabs, Carcinus aestuarii Nardo, 1847 belonging to the superfamily Portunoidea is newly reported from Korean waters. Carcinus aestuarii has characteristics as followings: cardiac, hepartic and brachial regions are divided by deep furrow; shape of three lobes in frontal area is flatter with hairy; inside of carpus is with one sharp tooth; the posterior-lateral margin of the carapace is concave, and so on. The examined specimen doesn't have hairy and bump on outer margin of the chelipeds which differed from the previous description of the specimens collected from Tokyo Bay, Japan. Here, the diagnosis and the picture of Korean specimen is provided. Korean portunoids currently consist of 20 species belonging to 10 genera.