• Title/Summary/Keyword: heat tolerance

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Clinical Applications of Microwave and Ultrasound in Hyperthermia: Preliminary Results (극초단파와 초음파온열치료에 의한 각종암의 임상치료)

  • Koh Kyoung Hwan;Park Young Hwan;Cho Chul Koo;Yoo Seong Yul
    • Radiation Oncology Journal
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    • v.6 no.1
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    • pp.75-80
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    • 1988
  • Twenty seven lesions of 25 patients with locally advanced malignant tumors were treated with combined hyperthermia introduced by microwave and ultrasound and radiotherapy. Most of all patients were failed with previous conventional therapeutic trial. Hyperthermia had been done immediately after radiotherapy, twice a week, $43^{\circ}C$ for one hour and radiotherapy had been done 5 fractions per week with fraction size of 2Gy upto 30 to 60Gy. Conclusions are as follows. 1. Total response rate (PR+PR) to thermoradiotherapy with microwave and ultrasound was $81\%$. 2. Tumor depth, minimum temperature of tumor center, number of heat fraction and radiation dose were statistically significant factors affecting response. 3. Hyperthermia with microwave and ultrasound can be used efficiently to control locally advanced malignant disease whether previously received near tolerance dose of radiotherapy or not.

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development of the High Utility Progressive Die for Sheet Metal Forming (Part 2)

  • Sim, Sung-Bo;Song, Young-Seok;Sung, Yul-Min
    • Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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    • 2000.10a
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    • pp.231-235
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    • 2000
  • Precision progressive die have used for above ten thousand pieces of lot size production part. In the field of design and making tool for press working, the progressive die for sheet metal (SPC, thickness : 2mm) is a specific division. In order to prevent the defects, the optimum design of the U-bending production part, strip layout, die design, die making and tryout etc. are necessary. They require analysis of many kinds of important factors, i.e. theory and practice of metal pres working and its phenomena, die structure, machining condition for die making, die materials, heat treatment of die component, know-how and so on. In this study, we designed and constructed a progressive die of multi-stage and performed try out. Out of these processes the die development could be taken for advance. Especially the result of tryout and its analysis become the characteristics of this paper (part 1 and part 2) that nothing might be ever seen before such as this type of research method on all the processes. In the part 2 of this study we treated die making and tryout mostly.

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Development of the Circular lancing Type Progressive Die for STS 304 Sheet Metal Working (Part 2)

  • Sim, Sung-Bo;Song, Young-Seok;Sung, Yul-Min
    • Proceedings of the Korean Society of Machine Tool Engineers Conference
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    • 2000.04a
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    • pp.218-223
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    • 2000
  • Ultra precision progressive die have used for above one million's lot size of production part. In the field of design and making tool for press working, the progressive die for sheet metal (STS 304, thickness : 0.5mm) is a specific division. In order to prevent the defects, the optimum design of the production part, strip layout, die design, die making and tryout etc. are necessary. They require analysis of many kinds of important factors, i.e. theory and practice of metal press working and its phenomena, die structure, machining condition for die making, die materials, heat treatment of die component, know-how and so on. In this study, we designed and constructed a progressive die of multi-stage and performed try out. Out of these processes the die development could be taken for advance. Especially the result of tryout and its analysis become the characteristics of this paper (part 1 and part 2) that nothing might be ever seen before such as this type of research method on all the processes. In the part 2 of this study we treated die making and tryout mostly.

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Comparative Analysis of the Growth for Selectively Bred Korean Turbot Scophthalmus maximus Population (한국 육종터봇(Scophthalmus maximus)의 성장률 비교 분석)

  • Kim, Min Sung;Kim, Tae Hwan;Han, Jae Yong;Jo, Hyeon Kyeong;Kwak, Ju Ri;Park, Ji Been;Suh, Jong-pyo;Lee, Woo-jai
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.53 no.4
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    • pp.563-565
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    • 2020
  • Turbot Scophthalmus maximus can be cultured at a higher density and has a faster growth rate than olive flounder Paralichthys olivaceus, making it an attractive alternative for flounder farmers in Korea. As it is a relatively new species to Korean farming environments, there is no general farming protocol, which takes multiple generations to develop, for turbot in Korea. Nevertheless, we applied breeding technology to develop a stock, which we considered first-generation turbot. Then we compared its growth rate (an important economic trait) to different populations (the original stock of Korean turbot, French turbot, and Chinese turbot). The four different populations were grown in similar culture conditions. First-generation Korean turbots grew about 28% faster than all others. We will continue to select for important traits such as color, disease resistance, and heat tolerance in this turbot broodstock; we believe that with the appropriate selection process, Korean turbot should become competitive in the markets, and will become a major farming species in the Korean aquaculture industry.

Lifespan-extending Effects of Allium hookeri Leaves in Caenorhabditis elegans (삼채 잎 추출물의 예쁜꼬마선충에 대한 수명연장 효과)

  • Ki, Byeolhui;Lee, Eun Byeol;Kim, Jun Hyeong;Yang, Jae Heon;Kim, Dae Keun;Kim, Young-Soo
    • Korean Journal of Pharmacognosy
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    • v.48 no.4
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    • pp.314-319
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    • 2017
  • To evaluate the longevity property of Allium hookeri (Liliaceae) leaves, this study was performed. Ethanol extract of A. hookeri was successively partitioned as methylene chloride, ethyl acetate, n-butanol and $H_2O$ soluble fractions, and lifespan-extending effects of the fractions were checked using Caenorhabditis elegans model system. The most active ethyl acetate-soluble fraction elevated heat stress tolerance, and increased expression of stress resistance protein. Further studies were performed to investigate several aging-related factors such as reproduction, food intake, growth and movement of C. elegans. The results revealed that there were no significant changes in aging-related factors including reproduction and food intake, however, ethyl acetate-soluble fraction treatment led to up-regulation of locomotory ability and growth of aged worms, suggesting ethyl acetate-soluble fraction affected healthspan as well as lifespan of nematode.

Effect of Cold Acclimatization Training on Body Composition (추위 훈련이 신체 조성에 미치는 영향 -체중, 체지방량, 골격근량을 중심으로-)

  • Park, Joo-Hee;Choi, Jeong-Wha
    • Journal of the Korean Society of Clothing and Textiles
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    • v.35 no.7
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    • pp.713-720
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    • 2011
  • This study investigated the effect of cold acclimatization training on body composition including weight, fat mass, and muscle mass with 10 subjects (5 males and 5 females). During the 3-week acclimatization training program, they visited an artificial climate chamber ($15^{\circ}C$) 15 times and were exposed to cold environment with light clothing for 2 hours. Body composition was measured before and after cold training using bioelectric impedance analysis that was later compared by a paired t-test. In the process of thermoregulation, muscle contraction was accompanied by increased substrate metabolism for rising heat production. After cold training, the muscle mass increased and fat mass decreased significantly (p<.1, p<.05), subsequently the body composition changed. It was found that cold acclimatization training could be used as a treatment for obesity. It was suggested that further investigation on the long term effects of mild cold exposure using clothing and its potential applicability as an obesity treatment.

Influence of Regular Jjimjilbang Exposure on Farmers' Physiological Responses (정기적인 찜질노출이 농업인의 생리반응에 미치는 영향)

  • Choi, Jeong-Wha;Song, Eun-Young;Park, Joon-Hee
    • Journal of the Korean Home Economics Association
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    • v.46 no.1
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    • pp.39-45
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    • 2008
  • We analyzed the effects of regular Jjimjilbang(Korean sauna) exposure on the physiological responses in seven elderly farmers(Male=3, Female=4). Jjimjil training group took a bath in Jjimjilbang 8 times twice a week. Jjimjibang exposure was limited three times per day. Rectal temperature, total sweat rate, body fat (%), blood pressure, pulse, $Na^+$ concentration in sweat, and subjective sensation were measured during Jjimjil training exposure. The results are as follow: During Jjimjil exposure, changes of rectal temperature in male farmers were more stabilized than female farmers. The gradual decrease in total sweat rate and Na+ concentration in sweat was observed in both sexes. After Jjimjil exposure, the decrease in blood pressure was observed in both sexes, but not observed changes according to regular Jjimjil exposure. Subjective thermal comfort sensation was changed positively. In conclusion, the regular Jjimjil exposure has positive effects upon improvement in regulation of body temperature, blood pressure, and $Na^+$ concentration especially in heat tolerance.

Isolation of Bacteriocin-producing Lactic Acid Bacteria from Human Intestines and the Characteristics of their Bacteriocins (Bacteriocin을 생산하는 장내 유산균의 분리 및 Bacteriocin 특성조사)

  • 김정환;맹길재;김정상;지근억
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.26 no.6
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    • pp.1228-1236
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    • 1997
  • Lactobacillus strains were isolated from volunteer's feces, including from newly-born infants and adults in their 20's, by using differential MRS-BPB plates. Total 56 presumptive Lactobacillus strains were isolated and the bacteriocin productions by the isolates were examined by agar diffusion method. Six bacteriocin-producing strains were confirmed. Among them, two isolates, HU-1 and H22-3, showed the most outstanding antimicrobial activities, which were not affected by pH adjustments or catalase treatments of culture. HU-1 was originated from a two-years old boy and H22-3 was originated from a newly-born infant. HU-1 and H22-3 had the same morphology(short rod) when examined by scanning electron microscope, and the same biochemical traits including growth temperature range, salt tolerance and sugar-fermenting abilities. But the growth-inhibition spectrum and plasmid profiles of HU-1 and H22-3 were different. Both strains inhibited the growth of various Gram (+) microorganisms including Listeria monocytogenes. Micrococcus luteus, and Staphylococcus aureus in addition to many species of lactic acid bacteria, indicating the production of broad-spectrum bacteriocins. Bacteriocins produced by HU-1 and H22-3 were stable up to 90℃, 15 min heat treatments. Their activities were not affected by pepsin or trypsin treatments but destroyed by proteinaseK or pronase treatments.

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A Study on the Limited Rate Power Capacity for Applications for Precision Passive Devices Based on Carbon Nanotube Materials (탄소나노튜브 소재의 정밀 수동소자 적용을 위한 한계 정격전력 용량에 관한 연구)

  • Lee, Sunwoo
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.35 no.3
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    • pp.269-274
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    • 2022
  • We prepared carbon nanotube (CNT) paper by a vacuum filtration method for the use of a chip-typed resistor as a precision passive device with a constant resistance. Hybrid resistor composed of the CNT resistor with a negative temperature coefficient of resistance (T.C.R) and a metal alloy resistor with a positive T.C.R could lead to a constant resistance, because the resistance increase owing to the temperature increase at the metal alloy and decrease at the CNT could counterbalance each other. The constant resistance for the precision passive devices should be maintained even when a heat was generated by a current flow resulting in resistance change. Performance reliabilities of the CNT resistor for the precision passive device applications such as electrical load limit, environmental load limit, and life limit specified in IEC 60115-1 must be ensured. In this study, therefore, the rated power determination and T.C.R tests of the CNT paper were conducted. -900~-700 ppm/℃ of TCR, 0.1~0.2 A of the carrying current capacity, and 0.0625~0.125 W of the rated power limit were obtained from the CNT paper. Consequently, we confirmed that the application of CNT materials for the precision hybrid passive devices with a metal alloy could result in a better performance reliability with a zero tolerance.

Changes in expression of monocarboxylate transporters, heat shock proteins and meat quality of Large White Yorkshire and Ghungroo pigs during hot summer period

  • Parkunan, Thulasiraman;Das, Arun K.;Banerjee, Dipak;Mohanty, Niharika;Paul, Avishek;Nanda, P.K.;Biswas, TK;Naskar, Syamal;Bag, Sadhan;Sarkar, Mihir;Mohan, Narayana H.;Das, Bikash Chandra
    • Asian-Australasian Journal of Animal Sciences
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    • v.30 no.2
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    • pp.246-253
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    • 2017
  • Objective: Present study explores the effect of hot summer period on the glycolytic rate of early post-mortem meat quality of Ghungroo and Large White Yorkshire (LWY) pig and comparative adaptability to high temperature between above breeds by shifting the expression of stress related genes like mono-carboxylate transporters (MCTs) and heat shock proteins (HSPs). Methods: Healthy pigs of two different breeds, viz., LYW and Ghungroo (20 from each) were maintained during hot summer period (May to June) with a mean temperature of about $38^{\circ}C$. The pigs were slaughtered and meat samples from the longissimus dorsi (LD) muscles were analyzed for pH, glycogen and lactate content and mRNA expression. Following 24 h of chilling, LD muscle was also taken from the carcasses to evaluate protein solubility and different meat quality measurements. Results: LWY exhibited significantly (p<0.01) higher plasma cortisol and lactate dehydrogenase concentration than Ghungroo indicating their higher sensitivity to high temperature. LD muscle from LWY pigs revealed lower initial and ultimate pH values and higher drip loss compared to Ghungroo, indicating a faster rate of pH fall. LD muscle of Ghungroo had significantly lower lactate content at 45 min postmortem indicating normal postmortem glycolysis and much slower glycolytic rate at early postmortem. LD muscle of LWY showed rapid postmortem glycolysis, higher drip loss and higher degrees of protein denaturation. Ghungroo exhibited slightly better water holding capacity, lower cooking loss and higher protein solubility. All HSPs (HSP27, HSP70, and HSP90) and MCTs (MCT1, MCT2, and MCT4) in the LD muscle of pigs inclined to increase more in Ghungroo than LWY when exposed to high temperature. Conclusion: Effect of high temperature on the variation of HSPs and MCTs may play a crucial role in thermal tolerance and adaptation to different climatic conditions, pH regulation, muscle acidification, drip loss, protein denaturation and also in postmortem meat quality development.