• BMB Reports
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• 제49권12호
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• pp.662-670
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• 2016

The human oral cavity contains a highly personalized microbiome essential to maintaining health, but capable of causing oral and systemic diseases. Thus, an in-depth definition of "healthy oral microbiome" is critical to understanding variations in disease states from preclinical conditions, and disease onset through progressive states of disease. With rapid advances in DNA sequencing and analytical technologies, population-based studies have documented the range and diversity of both taxonomic compositions and functional potentials observed in the oral microbiome in healthy individuals. Besides factors specific to the host, such as age and race/ethnicity, environmental factors also appear to contribute to the variability of the healthy oral microbiome. Here, we review bioinformatic techniques for metagenomic datasets, including their strengths and limitations. In addition, we summarize the interpersonal and intrapersonal diversity of the oral microbiome, taking into consideration the recent large-scale and longitudinal studies, including the Human Microbiome Project.

• Journal of Preventive Medicine and Public Health
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• 제55권1호
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• pp.1-9
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• 2022

An index that evaluates the health level of a population group considering both death and loss of function due to disease is called a summary measure of population health (SMPH). SMPHs are broadly divided into life year indices and life expectancy indices, the latter of which comprise healthy life expectancy (HLE). HLE is included as a policy target in various national and regional level healthcare plans, and the term "HLE" is commonly used in academia and by the public. However, the overall level of understanding of HLE-such as the precise definition of HLE and methods of calculating HLE-still seems to be low. As discussed in this study, the types of HLE are classified into disability-free life expectancy, disease-free life expectancy, quality-adjusted life expectancy, self-rated HLE, and disability-adjusted life expectancy. Their characteristics are examined to facilitate a correct understanding and appropriate utilization of HLE. In addition, the Sullivan method, as a representative method for calculating HLE, is presented in detail, and major issues in the process of calculating HLE, such as selection of the population group and age group, estimation of death probability, calculation of life years, and incorporation of health weights, are reviewed. This study will help researchers to select an appropriate HLE type and evaluate the validity of HLE research results, and it is expected to contribute to the vitalization of HLE research.

• 대한미생물학회지
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• 제17권1호
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• pp.1-6
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• 1982

To investigate the annual distribution of hepatitis B surface antigen(HBs Ag) in healthy adults, this study was performed by means of counter-immunoelectrophoresis with sera obtained from 4,856 healthy adults who reside in Seoul and Gyunggi-Do area from January to December, 1981. The experimental procedures were same with the previous reports. The subjectives were consisted of two groups: one is mass life group(3.853 adults) and the other, home life group(1.003 adults). The results were as follows: 1. Among the 4.856 cases tested, 326 cases(6.71%) showed HBs Ag positive. HBs Ag positive rates in the group of mass life and home life were 6.51% and 7.48%, respectively. 2. It showed slightly high positive rates in the home life and long term duration group, and upper class group showed slightly high positive rate. 3. In seasonal variation, it showed relatively high positive rate(7.38%) in winter, and A blood group showed higher rate(7.60%) than the other blood groups. And then, boundary area of Seoul city showed slightly high positive rate(7.36%) in areal distribution.

• Journal of Microbiology and Biotechnology
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• 제28권4호
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• pp.652-662
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• 2018

Diarrhea is a global disease with a high morbidity and mortality rate in children. In this study, 25 fecal samples were collected from children under 5 years old. Seven samples had been taken from healthy children without diarrhea and marked as the healthy control group; eight samples had been sampled from children with diarrhea caused by dyspepsia and defined as the non-infectious group; and ten samples had been taken from children with diarrhea induced by intestinal infections and identified as the infectious group. We detected the microbial communities of samples by using high-throughput sequencing of 16S rRNA genes. The proportion of aerobic and facultative anaerobic microbes in samples of the infectious group was much higher than in the non-infectious group. In addition, the relative abundance of Enterococcus in the healthy control group was significantly higher than in the non-infectious group and infectious group. This can be used as a potential diagnostic biomarker for diarrhea.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제47권5호
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• pp.351-359
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• 2021

Objectives: Despite treatment, the pre-traumatic facial appearance of patients with maxillofacial fractures might not be able to be restored, and this difference can affect the person's quality of life (QoL). This study was designed to evaluate changes in QoL of people with maxillofacial fractures. Materials and Methods: The study population was comprised of participants with maxillofacial fracture and age- and sex-matched healthy controls without history of such fracture. QoL was measured using the World Health Organization Quality of Life BREF (WHOQOL-BREF) questionnaire, which was administered to the patients before treatment (Time 1), at 6 weeks post-treatment (Time 2), and at 12 weeks postoperatively (Time 3). The values were compared with those of healthy controls. The QoL was compared between closed reduction group and open reduction and internal fixation group. Results: The QoL scores of people with maxillofacial fracture before treatment were significantly lower (P=0.001) than those of healthy controls in all domains of the WHOQOL-BREF. The QoL scores in the psychological and social domains of patients with maxillofacial fracture at Time 3 were still lower than those of healthy controls (P=0.001). Conclusion: The QoL of patients with maxillofacial fracture was significantly reduced before treatment in all domains and remained reduced in both psychological and social domains weeks after treatment. Therefore, clinicians must be aware of and manage the residual psychosocial issues that can accompany the post-treatment period of maxillofacial injury.

• 가정과삶의질연구
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• 제28권3호
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• pp.167-178
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• 2010

The purpose of this study was to analyze the healthy family education, healthy family counseling, a healthy family culture, and healthy families integrated programs for single parent families in family support centers, The data collected came from 59 family support centers located in Seoul and Kyunggi-Do, Korea. Subjects included both single parents and their children. The children were of elementary school age. The types of programs were education, counseling, culture, and integrated program. Education programs were process separately for the parents and for the children. Counseling programs were mostly group-type program that aimed at improving the parent-children relationship. The contents included sections on anger management, reducing stress, enriching self-esteem. The culture programs involved experiences, camps that included cooking, watching movies, similar activities. Integrated programs involved respite support, rearing support, mentor-mentee partnerships, and the formation of self-help groups.

• 가족자원경영과 정책
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• 제14권2호
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• pp.59-77
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• 2010

This research evaluated the present condition of the family voluntary service group and healthy family campaign, which was being carried out as one of the healthy family culture businesses of the Healthy Family-Support Center. Furthermore, it suggests ways to improve these business activities. Research centered on the analysis of business documents created between December 2006 and November 2007. The results were as follows. First, the family voluntary service group and the healthy family campaign business in the Center must be able to have specificity or individuality. Second, the Center must manage the scale, frequency, and contents of the businesses systematically. Third, the businesses must concern themselves with family life in general, make better use of the advisory committee or steering committee, concern variety of business performing system.

• 한국콘텐츠학회논문지
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• 제11권5호
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• pp.358-368
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• 2011

본 연구는 건강가정지원센터 상담사업 건강가정사의 직무연구를 통해 직무우선순위와 직무수행요건, 직무역량의 중요도와 교육요구도를 파악하고 핵심역량과 역량개발영역을 추출해내고자 수행되었다. 조사는 센터 내 상담사업분야에 종사하는 상근 및 비상근 건강가정사들을 대상으로 설문을 통해 이루어졌다. 분석결과 사업의 홍보 부분이 전략적 강화업무로 거론되었으며, 가족상담, 프로그램 기획, 사례회의, 슈퍼비젼등은 기본업무로 인식하고 있었다. 담당인력의 수행요건은 석사수준의 학력과 1-3년의 관련기관 근무경력, 가족상담사, 건강가정사, 사회복지사, 상담심리사 등의 자격인 것으로 나타났다. 그 외 직무역량 중요도와 교육요구도를 토대로 핵심역량과 역량개발영역을 추출하였는데 이것으로 상담영역 건강가정사의 직무 및 보수교육 콘텐츠 개발이 가능하다.

• 가정과삶의질연구
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• 제22권5호
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• pp.345-355
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• 2004

The purpose of this study is to recommend the roles, Qualification, and fostering system of healthy families specialist. In 2003, 'Organic Law to Develop the healthy Families' was legislated. The law endows the responsibilities and duties of the government, local government, and families, in order to embody the healthy families. Also, this suggests appropriate ways to solve diverse families problems and identifies the necessities of establishing social policies to increase the well-being of family members. The enactment system of this law is to place 'Healthy Families Center' under the Prime Minister, and to foster 'healthy families specialist' who have professional knowledge and skills for strengthen diverse families. The major recommend are as follow. First, the roles of healthy families specialist are a practician, deliverer, and administrator to enact the law's philosophy and ideal. Secondly, to protect the competency of those, the qualification is restricted to university and the same level school graduate people, who majored in Home Economics, Social Work. and Women Studies. Finally. to foster and qualify this specialist. the Council of Healthy Families will be compound.

• The Plant Pathology Journal
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• 제39권4호
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• pp.397-408
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• 2023

Fire blight disease, caused by Erwinia amylovora, is a devastating affliction in apple cultivation worldwide. Chemical pesticides have exhibited limited effectiveness in controlling the disease, and biological control options for treating fruit trees are limited. Therefore, a relatively large-scale survey is necessary to develop microbial agents for apple trees. Here we collected healthy apple trees from across the country to identify common and core bacterial taxa. We analyzed the endophytic bacterial communities in leaves and twigs and discovered that the twig bacterial communities were more conserved than those in the leaves, regardless of the origin of the sample. This finding indicates that specific endophytic taxa are consistently present in healthy apple trees and may be involved in vital functions such as disease prevention and growth. Furthermore, we compared the community metabolite pathway expression rates of these endophyte communities with those of E. amylovora infected apple trees and discovered that the endophyte communities in healthy apple trees not only had similar community structures but also similar metabolite pathway expression rates. Additionally, Pseudomonas and Methylobacterium-Methylorobrum were the dominant taxa in all healthy apple trees. Our findings provide valuable insights into the potential roles of endophytes in healthy apple trees and inform the development of strategies for enhancing apple growth and resilience. Moreover, the similarity in cluster structure and pathway analysis between healthy orchards was mutually reinforcing, demonstrating the power of microbiome analysis as a tool for identifying factors that contribute to plant health.