• Journal of Ecology and Environment
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• v.47 no.2
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• pp.42-48
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• 2023

An adult male Eurasian river otter (Lutra lutra) with ataxia and lethargy was rescued. Through the necropsy of this otter with neurological symptoms, a broad range of vascular damage caused by mercury toxicity in several organs, hepatocellular necrosis, and vacuolation in the brain. In mercury examination, liver, kidney, and hair showed values of 0.878 ± 0.027, 1.807 ± 0.049, and 5.712 ± 0.102 ㎍/g, respectively. Compared with certified reference material, it was confirmed that the concentration of mercury were 6.7 times, 13.7 times, and 43.3 times higher, respectively. When the symptoms and diagnosis results were comprehensively reviewed, this otter's demise was revealed due to mercury poisoning. The mercury concentration in the liver does not exceed the lowest observed effect level of 3.4 ㎍/g. However, even at low concentrations, long-term accumulation can cause symptoms including neuropathy, and the possibility that these heavy metals have accumulated in other wild animals cannot be ruled out. It seems that continuous monitoring using sentinel animals is necessary.

• International Journal of Precision Engineering and Manufacturing-Green Technology
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• v.9
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• pp.1563-1573
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• 2021

The impinging jet technique is a critical process for enhancing mechanical properties. Sensors for the precise diagnosis of the nozzle status are necessary to maintain product quality and reduce cost. The application of commercial sensors for this purpose is difficult because sensors in the casting, rolling, and reheating processes should provide sensitivity to small impact variations, durability, anticorrosion, waterproofing, and high-temperature endurance. We developed a sensor module to satisfy these engineering requirements. The sensor monitored impact pressures based on the reduction in the collision force caused by abnormal impinging jet flows. Smart signal filtering based on a low-pass filter was employed to achieve a short CPU time, noise discrimination, and the preservation of signal characteristics. A method for nozzle position synchronization and a new performance index for impinging jets for multiple-nozzle sensing in practical applications were also developed. The developed sensor module was validated using artificial abnormal nozzles and tested in the field. The validations showed that the developed sensor with the smart filter and nozzle synchronization method could provide an individual jet status with a high precision. The developed sensor is expected to contribute to the improvement of machine health monitoring technology in various fields with jet nozzles.

• International Journal of Aeronautical and Space Sciences
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• v.17 no.4
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• pp.535-550
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• 2016

Securing the safety and the reliability of liquid-propellant rocket engines (LREs) for space vehicles is indispensable as engines consist of many complex components and operate under extremely high energy-dense conditions. Thus, health monitoring has become a mandatory requirement, especially for the reusable LREs that are currently being developed. In this context, a dynamic simulation program based on MATLAB/Simulink was developed in the current research on the Space Shuttle Main Engine (SSME), a partly reusable engine. Then, a series of fault simulations using this program was conducted: at a steady state operating condition (104% Rated Propulsion Level), various simulated fault conditions were artificially injected into the simulation models for the five major valves, the pumps, and the turbines of the SSME. The consequent effects due to each fault were analyzed based on the time responses of the major parameters of the engine. It is believed that this research topic is an essential pre-step for the development of fault detection and diagnosis algorithms for reusable engines in the future.

• Smart Structures and Systems
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• v.29 no.6
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• pp.785-790
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• 2022

Condition monitoring of permanent magnet synchronous motors (PMSMs) and detecting faults such as eccentricity and demagnetization are essential for ensuring system reliability. Motor current signal analysis is the most commonly used precursor for detecting faults in the PMSM drive system. However, the current signature responds sensitively to the load and temperature of the motor, thereby making it difficult to monitor faults in real- applications. Therefore, in this study, a condition monitoring methodology that detects motor faults, including their classification with standstill conditions, is proposed. The objective is to detect and classify faults of PMSMs by using programmable inverter without additional sensors and systems for detection. Both DC and AC were applied through the d-axis of a three-phase motor, and the change in incremental inductance was investigated to detect and classify faults. Simulation with finite element analysis and experiments were performed on PMSMs in healthy conditions as well as with eccentricity and demagnetization faults. Based on the results obtained from experiments, the proposed method was confirmed to detect and classify types of faults, including their severity.

• BMB Reports
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• v.55 no.9
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• pp.465-471
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• 2022

Understanding and monitoring virus-mediated infections has gained importance since the global outbreak of the coronavirus disease 2019 (COVID-19) pandemic. Studies of high-throughput omics-based immune profiling of COVID-19 patients can help manage the current pandemic and future virus-mediated pandemics. Although COVID-19 is being studied since past 2 years, detailed mechanisms of the initial induction of dynamic immune responses or the molecular mechanisms that characterize disease progression remains unclear. This study involved comprehensively collected biospecimens and longitudinal multi-omics data of 300 COVID-19 patients and 120 healthy controls, including whole genome sequencing (WGS), single-cell RNA sequencing combined with T cell receptor (TCR) and B cell receptor (BCR) sequencing (scRNA(+scTCR/BCR)-seq), bulk BCR and TCR sequencing (bulk TCR/BCR-seq), and cytokine profiling. Clinical data were also collected from hospitalized COVID-19 patients, and HLA typing, laboratory characteristics, and COVID-19 viral genome sequencing were performed during the initial diagnosis. The entire set of biospecimens and multi-omics data generated in this project can be accessed by researchers from the National Biobank of Korea with prior approval. This distribution of large-scale multi-omics data of COVID-19 patients can facilitate the understanding of biological crosstalk involved in COVID-19 infection and contribute to the development of potential methodologies for its diagnosis and treatment.

• Quality Improvement in Health Care
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• v.2 no.2
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• pp.20-30
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• 1996

Background : Theoretically as the waiting-time of patient is estimated in queueing, many men and much money are needed. But being the estimation of patient s waiting-time very important in hospital service, so the continuous monitoring of waiting-time is inevitable. To verify that the estimation of waiting-time using parking time is economical, effective and continuous monitoring method and to develop utilizing the method, this study was done. Method : In parking confirmation office, the personnel of parking office wrote parking confirm time, chart number and whether medical examination and treatment finish or not in parking ticket. The next day the parking tickets were gathered and the above data were input. The input parking data were connected with the hospital outpatient file indexing chart number. Then the patient' s data for department, new patient or not, reservation or not, receipt time and payment time were retrieved. The group for finishing medical treatment were compared with that for not finishing in average time lag between confirmation and out-time for hospital. And In-time for hospital, receipt time, payment and out-time for hospital were also analyzed. Result : Confirming parking ticket, the group for finished medical treatment left hospital after 7 minutes. This result showed that the patient for finished medical treatment left hospital immediately. So parking time was reasonable to estimation of hospital-time was concluded. The time for medical treatment, diagnosis and test was constant for all patients and short for waiting time, Then I concluded that the parking time was reasonable for estimation patient's waiting time. Overall patient's waiting time was 113 minutes and new patient's time was 149 minutes, old patient's times was 109 minutes. Waiting time for reservation patient was 98 minutes and for non reservation patient was 122 minutes. The time from hospital arrival to payment was 50 minutes for the group of reservation patient and 69 minutes for non-reservation group. The time from payment to hospital leaving was 51 minutes and 56 minutes for non reservation group. The short time difference between reserved group and not reserved group from payment to hospital leaving time was due to bottle neck effect. Conclusion : The estimation of patient's waiting time using parking time was reasonable because the possession of car was common and the time for medical treatment was equal and the patient after treatment left hospital immediately. Using this method, timely, fast evaluation and continuous monitoring of the intervention effect were possible.

• Journal of Environmental Health Sciences
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• v.38 no.5
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• pp.398-406
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• 2012

Objectives: In order to investigate the relation between environmental pollution and its effect on human health in large-scale industrial complex regions, monitoring studies have been conducted since 2003. The main purpose of this Gangneung study is to produce background data which can be compared with several large-scale industrial complex regions such as Ulsan, Sihwa, Banwol, Gwangyang, Yeosu, Pohang and Cheongju Daesan industrial complexes. Methods: In this Gangneung study, 1,007 local residents were recruited and the framework of this study was designed to evaluate and monitor health effects associated with low-level but long-term exposure to environmental pollutants. A survey was performed based on personal questionnaires, medical check-ups, and allergy skin prick tests for twelve common allergens. The authors reviewed the prevalence rate of skin allergens in Gangneung compared with in large-scale industrial areas. The results are summarized as follows. Results: The diagnosis prevalence and medical treatment prevalence of asthma were lower than in industrial complex regions, but allergic rhinitis was higher. The allergy skin test prevalence was 26.0% and the most common allergens were dust mites (D. pteronysinus 16.7% and D. farinae 16.3%). Conclusions: The positive findings of the skin prick test were similar with large-scale industrial complex regions in Korea. Further study is required to find the cause of the regional differences in skin prick prevalence.

• Journal of the Korea Society of Computer and Information
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• v.17 no.7
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• pp.97-106
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• 2012

Management of biosignal data in mobile devices causes many problems in real-time transmission of large volume of multimedia data or storage devices. Therefore, this research paper intends to suggest an m-Health system, a clinical data processing system using mobile in order to provide quick medical service. This system deployed health system on IP network, compounded outputs from many bio sensing in remote sites and performed integrated data processing electronically on various bio sensors. The m-health system measures and monitors various biosignals and sends them to data servers of remote hospitals. It is an Android-based mobile application which patients and their family and medical staff can use anywhere anytime. Medical staff access patient data from hospital data servers and provide feedback on medical diagnosis and prescription to patients or users. Video stream for patient monitoring uses a scalable transcoding technique to decides data size appropriate for network traffic and sends video stream, remarkably reducing loads of mobile systems and networks.

• Journal of Preventive Medicine and Public Health
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• v.55 no.1
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• pp.60-67
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• 2022

Objectives: This study investigated the determinants of undiagnosed hypertension among Indonesian adults. Methods: This study involved an analysis of secondary data from the 2014 Indonesia Family Life Survey (IFLS) on 5914 Indonesian adults (≥40 years). The determinant variables examined in this cross-sectional study were education level, monthly per capita expenditures (PCE), whether the participant experienced headaches in the morning, and other general health variables. The outcome variable was undiagnosed hypertension, which was defined as participants with hypertension who had not received a hypertension diagnosis from a health professional and had never been prescribed medication for treating hypertension. The data were analyzed using logistic regression. Results: A total of 3322 participants (56.2%) were found to have undiagnosed hypertension. The odds ratios (ORs) and 95% confidence intervals (CIs) of undiagnosed hypertension were significantly higher among those who completed primary school or lower (OR, 1.60; 95% CI, 1.29 to 1.98), had low monthly PCE (OR, 1.28; 95% CI, 1.13 to 1.43), did not report experiencing headaches in the morning (OR, 1.97; 95% CI, 1.76 to 2.21), and reported a general health status of healthy (OR, 2.05; 95% CI, 1.82 to 2.30) than those who had a higher education level, had high monthly PCE, experienced headaches in the morning, and were unhealthy. Conclusions: Education level, monthly PCE, the experience of headaches in the morning, and general health status were associated with undiagnosed hypertension. The monitoring system for detecting undiagnosed hypertension cases must be strengthened. Health promotion is also necessary to reduce the prevalence of undiagnosed hypertension.

• Clinical and Experimental Pediatrics
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• v.52 no.7
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• pp.745-751
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• 2009

Hypertension is a major risk factor for myocardial infarction, stroke, and cardiovascular mortality in adults; its treatment reduces the risk of cardiovascular events. In recent times, attention is being paid to monitoring of blood pressure from childhood to adulthood. Childhood hypertension is associated with hypertension in later life, and early intervention is important. In the Korean socioeconomic background, a rapid increase is observed in the number of obesity cases and the rate of increase in the incidence of obesity is more in childhood. The strong association of high blood pressure with obesity and the marked increase in the incidence of childhood obesity indicate that both hypertension and prehypertension are becoming significant health issues. In this comprehensive review, we acquaint the clinician with the available literature on childhood hypertension to provide recommendations for the diagnosis, evaluation, and treatment of hypertension based on the available evidence and consensus in Korean clinical conditions.