• Title/Summary/Keyword: health damage

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Oxidative DNA Damage from Nanoparticle Exposure and Its Application to Workers' Health: A Literature Review

  • Rim, Kyung-Taek;Song, Se-Wook;Kim, Hyeon-Yeong
    • Safety and Health at Work
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    • 제4권4호
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    • pp.177-186
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    • 2013
  • The use of nanoparticles (NPs) in industry is increasing, bringing with it a number of adverse health effects on workers. Like other chemical carcinogens, NPs can cause cancer via oxidative DNA damage. Of all the molecules vulnerable to oxidative modification by NPs, DNA has received the greatest attention, and biomarkers of exposure and effect are nearing validation. This review concentrates on studies published between 2000 and 2012 that attempted to detect oxidative DNA damage in humans, laboratory animals, and cell lines. It is important to review these studies to improve the current understanding of the oxidative DNA damage caused by NP exposure in the workplace. In addition to examining studies on oxidative damage, this review briefly describes NPs, giving some examples of their adverse effects, and reviews occupational exposure assessments and approaches to minimizing exposure (e.g., personal protective equipment and engineering controls such as fume hoods). Current recommendations to minimize exposure are largely based on common sense, analogy to ultrafine material toxicity, and general health and safety recommendations.

노인들의 건강식품 관련 문제 경험에 대한 대응 행동에 관한 연구 (A Study on the Reaction towards Damage Related to Health Foods among the Elderly)

  • 김효정;김미라
    • 동아시아식생활학회지
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    • 제18권4호
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    • pp.608-617
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    • 2008
  • This study examined the level of reaction towards damage related to health foods and the factors affecting this reaction among the elderly. Data were collected from 269 elderly individuals living in Seoul, Daejeon, Daegu, Gwangju and Busan. Frequencies, chi-square tests, and a multinomial logistic regression analysis were performed using the SPSS v. 14.0 program. When asked about their reaction towards damage related to health foods, approximately 48% of the respondents answered 'no response', 34% answered 'private response', and 18% answered 'public response'. Multinomial logistic regression analysis revealed that education level and awareness of health food price were significant factors influencing 'private response', and concerns about health foods and awareness of damage redemption were significant factors for 'public response'. These results imply that consumer education for elderly to prevent damage derived from the purchase and consumption of health foods is required.

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Iterative damage index method for structural health monitoring

  • You, Taesun;Gardoni, Paolo;Hurlebaus, Stefan
    • Structural Monitoring and Maintenance
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    • 제1권1호
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    • pp.89-110
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    • 2014
  • Structural Health Monitoring (SHM) is an effective alternative to conventional inspections which are time-consuming and subjective. SHM can detect damage early and reduce maintenance cost and thereby help reduce the likelihood of catastrophic structural events to infrastructure such as bridges. After reviewing the Damage Index Method (DIM), an Iterative Damage Index Method (IDIM) is proposed to improve the accuracy of damage detection. These two damage detection techniques are compared based on damage on two structures, a simply supported beam and a pedestrian bridge. Compared to the traditional damage detection algorithm, the proposed IDIM is shown to be less arbitrary and more accurate.

해상풍력터빈 트라이포드 지지구조물의 건전성 모니터링 기법 (Structural Health Monitoring Technique for Tripod Support Structure of Offshore Wind Turbine)

  • 이종원
    • 풍력에너지저널
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    • 제9권4호
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    • pp.16-23
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    • 2018
  • A damage detection method for the tripod support structure of offshore wind turbines is presented for structural health monitoring. A finite element model of a prototype tripod support structure is established and the modal properties are calculated. The degree and location of the damage are estimated based on the neural network technique using the changes of natural frequencies and mode shape due to the damage. The stress distribution occurring in the support structure is obtained by a dynamic analysis for the wind turbine system to select the output data of the neural network. The natural frequencies and mode shapes for 36 possible damage scenarios were used for the input data of the learned neural network for damage assessment. The estimated damages agreed reasonably well with the accurate ones. The presented method could be effectively applied for damage detection and structural health monitoring of various types of support structures of offshore wind turbines.

환경보건종합계획을 통해 살펴본 환경보건정책: 지난 10년과 향후 10년 (Environmental Health Policies for the Past and Coming Decade in South Korea)

  • 이종태
    • 한국환경보건학회지
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    • 제47권5호
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    • pp.379-383
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    • 2021
  • This paper discussed environmental health policies for the past and coming decade by reviewing the First Comprehensive Environmental Health Plan (2011~2020) and introducing the Second Comprehensive Environmental Health Plan (2021~2030). The major achievement of the First Comprehensive Environmental Health Plan was the establishment of receptor-oriented environmental health policies. However, the main limitations were insufficient policy support for relief and/or recovery from environmental pollution damage and low public awareness of environmental health policies. The Second Comprehensive Environmental Health Plan presents the following major policy tasks: establish an omnidirectional environment health investigation and monitoring system, provide customized environmental health services, improve the environmental health damage relief and recovery system, and promote regional environmental health policies. The Second Plan has a clear distinction from the First Plan in that it expands the field of environmental health from the prevention and management of environmental risk factors to proactive damage response and recovery, which will effectively contribute to alleviating the burden of environmental disease.

일부 자원 여성에서 모발염색 후 림프구의 DNA손상과 관련 요인 (DNA Damage in Lymphocytes after Hair Dyeing and Related Factors among Women Volunteers)

  • 조진아;오은하;설동근;이은일
    • Journal of Preventive Medicine and Public Health
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    • 제35권4호
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    • pp.275-281
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    • 2002
  • Objectives : To evaluate the DNA damage by hair dyeing in human lymphocytes Methods : Comet assays were carried out to evaluate the DNA damage in lymphocytes by hair dyeing. Twenty subjects were selected from women volunteers whose age ranged from 55 to 67 year old. All subjects had no smoking history. Blood samples were collected before and 6 hours after hair dyeing. DNA damage was evaluated by means of the tail moments, which were quantified by a KOMET 4.0 image analysis system. Results : The tail moments before hair dyeing showed no significant differences among subjects except for the high frequency group. The mean values of the tail moments in subjects with low and high frequencies of hair dyeing were 1.39 and 1.77, respectively (p<0.05). The tail moments after hair dyeing increased significantly, The mean values of tail moments in subjects before and after hair dyeing were 1.45 and 1.79, respectively (p<0.01). However, the difference levels of DNA damage in lymphocytes before and after hair dyeing were found to be slightly lower in both the dietary supplement taking group and high frequency group. Conclusions : The high frequency group appears to have a higher level of DNA damage than the low frequency group before hair dyeing. DNA damage in lymphocytes was found to be significantly higher in the volunteers after hair dyeing. In this study, the related factors such as high frequency and taking dietary supplements appeard to reduce DNA damage in lymphocytes after hair dyeing.

Damage assessment of structures - an US air force office of scientific research structural mechanics perspective

  • Giurgiutiu, Victor
    • Smart Structures and Systems
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    • 제6권2호
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    • pp.135-146
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    • 2010
  • This paper presents the perspective of the Structural Mechanics program of the Air Force Office of Scientific Research (AFOSR) on the damage assessment of structures for the period 2006-2009 when the author was serving as Program Manager at AFOSR. It is found that damage assessment of structures plays a very important role in assuring the safety and operational readiness of US Air Force fleet. The current fleet has many aging aircraft, which poses a considerable challenge for the operators and maintainers. The nondestructive evaluation technology is rather mature and able to detect damage with considerable reliability during the periodic maintenance inspections. The emerging structural health monitoring methodology has great potential, because it will use on-board damage detection sensors and systems, will be able to offer on-demand structural health bulletins. Considerable fundamental and applied research is still needed to enable the development, implementation, and dissemination of structural health monitoring technology.

A hybrid structural health monitoring technique for detection of subtle structural damage

  • Krishansamy, Lakshmi;Arumulla, Rama Mohan Rao
    • Smart Structures and Systems
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    • 제22권5호
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    • pp.587-609
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    • 2018
  • There is greater significance in identifying the incipient damages in structures at the time of their initiation as timely rectification of these minor incipient cracks can save huge maintenance cost. However, the change in the global dynamic characteristics of a structure due to these subtle damages are insignificant enough to detect using the majority of the current damage diagnostic techniques. Keeping this in view, we propose a hybrid damage diagnostic technique for detection of minor incipient damages in the structures. In the proposed automated hybrid algorithm, the raw dynamic signatures obtained from the structure are decomposed to uni-modal signals and the dynamic signature are reconstructed by identifying and combining only the uni-modal signals altered by the minor incipient damage. We use these reconstructed signals for damage diagnostics using ARMAX model. Numerical simulation studies are carried out to investigate and evaluate the proposed hybrid damage diagnostic algorithm and their capability in identifying minor/incipient damage with noisy measurements. Finally, experimental studies on a beam are also presented to compliment the numerical simulations in order to demonstrate the practical application of the proposed algorithm.

Three-dimensional structural health monitoring based on multiscale cross-sample entropy

  • Lin, Tzu Kang;Tseng, Tzu Chi;Lainez, Ana G.
    • Earthquakes and Structures
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    • 제12권6호
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    • pp.673-687
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    • 2017
  • A three-dimensional; structural health monitoring; vertical; planar; cross-sample entropy; multiscaleA three-dimensional structural health monitoring (SHM) system based on multiscale entropy (MSE) and multiscale cross-sample entropy (MSCE) is proposed in this paper. The damage condition of a structure is rapidly screened through MSE analysis by measuring the ambient vibration signal on the roof of the structure. Subsequently, the vertical damage location is evaluated by analyzing individual signals on different floors through vertical MSCE analysis. The results are quantified using the vertical damage index (DI). Planar MSCE analysis is applied to detect the damage orientation of damaged floors by analyzing the biaxial signals in four directions on each damaged floor. The results are physically quantified using the planar DI. With progressive vertical and planar analysis methods, the damaged floors and damage locations can be accurately and efficiently diagnosed. To demonstrate the performance of the proposed system, performance evaluation was conducted on a three-dimensional seven-story steel structure. According to the results, the damage condition and elevation were reliably detected. Moreover, the damage location was efficiently quantified by the DI. Average accuracy rates of 93% (vertical) and 91% (planar) were achieved through the proposed DI method. A reference measurement of the current stage can initially launch the SHM system; therefore, structural damage can be reliably detected after major earthquakes.

Evaluation of typhoon induced fatigue damage using health monitoring data for the Tsing Ma Bridge

  • Chan, Tommy H.T.;Li, Z.X.;Ko, J.M.
    • Structural Engineering and Mechanics
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    • 제17권5호
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    • pp.655-670
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    • 2004
  • This paper aims to evaluate the effect of typhoons on fatigue damage accumulation in steel decks of long-span suspension bridges. The strain-time histories at critical locations of deck sections of long-span bridges during different typhoons passing the bridge area are investigated by using on-line strain data acquired from the structural health monitoring system installed on the bridge. The fatigue damage models based on Miner's Law and Continuum Damage Mechanics (CDM) are applied to calculate the increment of fatigue damage due to the action of a typhoon. Accumulated fatigue damage during the typhoon is also calculated and compared between Miner's Law and the CDM method. It is found that for the Tsing Ma Bridge case, the stress spectrum generated by a typhoon is significantly different than that generated by normal traffic and its histogram shapes can be described approximately as a Rayleigh distribution. The influence of typhoon loading on accumulative fatigue damage is more significant than that due to normal traffic loading. The increment of fatigue damage generated by hourly stress spectrum for the maximum typhoon loading may be much greater than those for normal traffic loading. It is, therefore, concluded that it is necessary to evaluate typhoon induced fatigue damage for the purpose of accurately evaluating accumulative fatigue damage for long-span bridges located within typhoon prone regions.