• Medical Lasers
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• 제10권4호
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• pp.195-200
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• 2021

Evidence shows that nerve injury triggers mitochondrial dysfunction during axonal degeneration. Mitochondria play a pivotal role in axonal regeneration. Therefore, normalizing mitochondrial energy metabolism may represent an elective therapeutic strategy contributing to nerve recovery after damage. Photobiomodulation (PBM) induces a photobiological effect by stimulating mitochondrial activity. An increasing body of evidence demonstrates that PBM improves ATP generation and modulates many of the secondary mediators [reactive oxygen species (ROS), nitric oxide (NO), cyclic adenosine monophosphate (cAMP), and calcium ions (Ca²⁺)], which in turn activate multiple pathways involved in axonal regeneration.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2006년도 춘계학술대회 논문집
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• pp.643-644
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• 2006

The purpose of this study is to experimentally analyze swing motion with soft golf clubs and compare with that with normal golf clubs. Soft golf is newly devised recreational sport based on golf but focus on the playability for the elderly. The subject fur the experiment performed swing motion using a normal golf club and a soft golf club in turn. The swing motion of the subjects was tracked using an opto-electric three-dimensional motion analysis system. The results were compared against those obtained with a normal golf club. The range of motion was analyzed along with top head speed for two cases. It was found that higher club head speed could be achieved with reduced range of motion at lumbar joint using soft golf club when compared against the swing using regular club. The lower range of motion fur lumbar bending means reduced risk of injury at the joint. So, it is projected that we can reduce the risk of injury with soft golf while maintaining the club head speed.

• 대한두개안면성형외과학회지
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• 제21권1호
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• pp.27-34
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• 2020

Background: Free-flap reconstruction for recurrent head and neck cancer may be challenging depending on the previous treatments, those are, chemotherapy, radiotherapy, and surgery, including neck dissection or free tissue transfer. Specifically, the previous treatment could compromise the neck vessels, thereby making free-flap reconstruction more difficult. This study aimed to investigate the correlation between previous treatments and vascular compromise of the free flap. Methods: In this retrospective study, 124 free-flap reconstructions in 116 patients for recurrent head and neck cancer between 1993 and 2017 were investigated. The demographic characteristics, previous treatments, flap choices, infections, recipient vessels, and vascular crises were evaluated. Results: Of the 124 reconstruction cases, 10 had vascular crises. There were six revisions, totaling six flap failures. The success rate of free-flap reconstruction for recurrent cancer was 95.2%, which significantly differed from that for primary cancer (98.8%, p= 0.006). Moreover, in the recurrent cancer group, no correlation was found between previous treatments and vascular crises (p> 0.05). Increased rates of contralateral or uncommon anastomoses were found following neck dissection (p< 0.05). Conclusion: Previous neck dissection or radiotherapy could lead to scarring and tissue damage, which could in turn make microvascular reconstruction more challenging; however, the effect was not definite in this study. Approximately 60% of patients with previous neck dissection had compromised ipsilateral recipient vessels, which resulted in contralateral or uncommon anastomoses. In this study, free-flap reconstruction seems to be quite safe and preferable in patients with recurrent head and neck cancer based on the overall survival rate.

• 한국ITS학회 논문지
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• 제5권1호
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• pp.21-30
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• 2006

중앙버스전용차로제가 도입됨에 따라 서울의 도로환경은 단기간에 급격하게 변하였으며, 이러한 급격한 변화에 미리 준비되지 못하였던 신호운영상의 문제점들이 경험되고 있다. 장 임계적인 문제점으로 중앙버스전용차로 설치구간 신호교차로에서 일반차량 좌회전 진행을 허용할 경우, 현재 우리나라가 규정하고 있는 차량 4색신호등의 한계로 인한 신호의 비효율적 운영이다. 중앙버스전용차로 설치구간 신호교차로에서 일반차량 좌회전의 현실적 운영방안 마련이 필요하다. 본 연구는 중앙차로전용신호의 도입을 준비하기 위하여 교통관제센터의 신호운영모드별 선행좌회전 및 후행좌회전 운영방안을 검토하고, 각 운영방안 별 Signal Map 구성방안을 점검한다. Signal Map 작성방안을 검토한 결과 기존의 신호제어 장비에 추가의 신호등기신호보드를 활용하는 방법으로 제안된 방법의 현장 적용이 용이한 것으로 확인되었다.

• 대한두경부종양학회지
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• 제17권2호
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• pp.169-173
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• 2001

Objectives: The p53 tumor suppressor gene encodes a nuclear transcription factor that is critical regulator of cell growth and proliferation through its action in cell-cycle checkpoint control. The wide variety of stressful stmuli which include DNA damage, hypoxia, heat shock, metabolic changes activate the p53 protein, which in turn drives a series of events that culminate either in cell cycle arrest or apoptosis. Mutations of the p53 gene is the most common genetic alteration in human cancer. This gene is altered in approximately 40-60% of head and neck cancers. Whereas the wild-type form of the p53 protein plays a central role in cell-cycle control in response to DNA damage, most of the mutant forms are unable to do so. The high levels of p53 protein expression in tissues are related to the increased cellular proliferative activity and may be associated with the poor clinical outcome. To determine whether the expression of the p53 protein has prognostic significance and is associated with patterns of treatment failure in head and neck squamous cell carcinoma (HNSCC), We analyzed p53 overexpression in 40 cases of HNSCC. Materials and Methods: Immunohistochemical analysis with a monoclonal antibody (DO7) specific for p53 protein was used to detect expression of the protein in formalin-fixed, paraffin-embedded tumor samples from 40 HNSCC. We evaluated p53 protein expression and analyzed the relationship between the p53 overexpression and age, sex, primary tumor site, stage, survival rate, recurrence. All reported P values resulted from two-sided statistical tests. Results: Overexpression of p53 was detected in 20 cases(50%) among 40 cases of HNSCC. The p53 overexpression was not associated with age, sex, primary tumor site, stage, recurrence and survival rate. Conclusions: In our results, p53 was not significant prognostic factor in HNSCC. Based on many previous studies, It is evident that p53 has a certain role in tumorigenesis of HNSCC. So, the further study is needed to evaluate the prognostic significance of p53 in HNSCC.

• 간호행정학회지
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• 제6권1호
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• pp.109-122
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• 2000

The present study examined the causal relationships among nurses' perceived autonomy, job satisfaction, work environment (work overload, role conflict, situational support, head nurses' leadership), personal aspects(experiences, need for achievement, professional knowledge and skill) by constructing and testing a theoretical framework. Based on literature review nurses' perceived autonomy and job satisfaction were conceived of as outcomes of the interplay among work environment and personal characteristics. Work environment factors involved work overload, role conflict, situational support, and head nurses' leadership (task oriented leadership, relation oriented leadership). Personal charateristics included experiences, need for achievement, and professional knowledge and skill. Three large general hospital in Chonbuk were selected to participate. The total sample of 516 registered nurses represents a response rate of 92 percent. Data for this study was collected from July to September in 1998 by Questionnaire. Path analyses with LISREL 7.16 program were used to test the fit of the proposed conceptual model to the data and to examine the causal relationship among variables. The result showed that both the proposed model and the modified model fit the data excellently. It needs to be notified, however, that path analisis can not count measurement errors; measurement error can attenuate estimates of coefficient and explanatory power. Nevertheless the model revealed relatively high explanatory power. 42 percent of nurses' perceived autonomy was explained by predicted variables; 32 percent of nurses' job satisfaction was explained by by predicted variables. Tn predicting nurses' perceived autonomy the findings of this study clearly demonstrated the work overload might be the most important variable of all the antecedent variables. Head nurses' relation oriented leadership, situational supports, need for achievement, and role conflict were also found to be important determinants for nurses' perceived autonomy. As for the job satisfaction, role conflict, situational supports, need for the achievement, and head nurses' relation oriented leadership were in turn important predictors. Unexpectedly the result showed perceived autonomy have few influence on job satisfaction. The results were discussed, including directions for the future research and practical implication drawn from the research were suggested.

• 소성∙가공
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• 제25권1호
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• pp.29-35
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• 2016

In the current study, finite element analysis was conducted for the press hemming of automotive panels in order to predict various hemming defects such as roll-in and turn down. The analysis used the exact punch movement based on the cam location and considered the sealer between the inner and outer panels with an artificial contact thickness. The analysis results quantify the hemming defects especially at the flange edge in the matching region of the head lamp. A design of experiments along with the parameter study was used to obtain the optimum process parameters for minimizing hemming defects. The optimization process selects the intake angle, bending angle of the hemming punch, and the flange height of the outer panel. The optimum design process determines an appropriate tool angle and flange height to reduce the roll-in and turn-down as compared to the initial design.

• 한국생산제조학회지
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• 제23권5호
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• pp.435-442
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• 2014

This paper describes an improved design model that can be used to configure a non-contact pneumatic device to turn a large sheet at the in-line system. For rotational moving in the conveyor system, the conventional method is to turn the system itself. The improved non-contact pick-up system mainly uses 8 pairs of L-shaped latches and 12 swirl type heads. It is positioned above the upward air flow table. This system performs the non-contact gripping and side-edge contact support in the vertical and rotational directions to hold the self-weight of a large flat sheet. A non-contact air head can exert a sufficient gripping ability at 4N lower than the standard working pressure. The side latches support 60% of the lifting force required. Through structural and flow analysis, the working conditions were simultaneously considered in accordance with the deflection and flatness of the glass.

• 정보저장시스템학회:학술대회논문집
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• 정보저장시스템학회 2005년도 추계학술대회 논문집
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• pp.96-102
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• 2005

The tribocharge build-up in the slider disk interface can cause ESD (electrostatic discharge) damage. In turn, ESD can cause severe melting damage to MR or GMR heads. We investigated the tribovoltage/current build-up with smooth and textured disks in HDD, operating at increasing disk accelerations. We found that tribe-voltage/current were generated during pico-slider/disk interaction and those levels were about 0.1 ${\~}$ 0.3 V and 10 ${\~}$ 40 pA, respectively. Tribovoltage/current were abruptly increased and dissipated within the acceleration time in the case of textured disk but in the case of smooth disk tribovoltage was continuously increased until the end of uniform velocity region and the tribocurrent did not dissipate within the acceleration time. In the case of textured dist tribovoltage/current was reduced with increasing disk acceleration, but in the case of smooth disk it was increased.

• 한국전자통신학회논문지
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• 제6권3호
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• pp.439-444
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• 2011

본 논문에서는 자동차에서 자동차의 속도, 엔진 회전속도, 연료, 엔진 온도, 연료 게이지, 회전표시등과 각종 경보 표시등 정보를 운전자에게 제공하는 차세대용 지능형 통합 스마트 모니터 시스템을 구현하였다. 구현한 지능형 스마트 HUD 모니터 시스템은 박막 트랜지스터 액정 표시 장치, 액정 표시 장치 배경 조명 발광 다이오드, 평면 미러, 특수 제작된 렌즈 및 구동회로로 구성되어 있으며, 운전자 안전성을 고려한 차세대 지능형 자동차 통합 HUD 시스템에 적용 가능함을 나타내었다.