• 제목/요약/키워드: half-lives

검색결과 297건 처리시간 0.034초

NEMA NU2-2001을 이용한 PET-CT 스캐너의 물리적 특성평가 (Evaluation of Physical Characteristics of Discovery ST scanner Using NEMA NU2-2001 Standard)

  • 이병일
    • 통합자연과학논문집
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    • 제1권2호
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    • pp.79-83
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    • 2008
  • As a new standard for performance measurement, NEMA NU2-2001 was presented recently. In this study, I investigated the spatial resolution, sensitivity, scatter fraction, and noise equivalent count ratio (NECR) in order to know the information of physical characteristics and system performance of GE discovery ST using this new standard. Bismuth germinate crystals ($6{\times}6$ array, $6.3mm{\times}6.3mm{\times}30mm$) were used in discovery ST (energy window:375-650 keV, coincidence window:11.7 nsec). To measure the sensitivity, five aluminum sleeves (Data Spectrum Corp., Chapel Hill, NC., USA, thickness:1.25 mm)-NEMA sensitivity phantom- filled with F-18 solution were used. Successive measurements in 2D and 3D acquisition mode were made with a line source at the center of transaxial field of view and 10 cm off from the center until the count was over 500,000. Spatial resolution was estimated using a point source (F-18, 0.1 mCi) at different locations in the FOV. Scatter fraction and NECR was tested using a NEMA scatter phantom. Dynamic data were acquired for 7 half-lives using F-18 solution. And true to background ratio was averaged at last three frames when the random rate was as small as ignorable for the calculation of scatter fraction. We anticipate this overall evaluated results could be used for the quality assurance and optimized image acquisition for clinical research.

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형질전환 Chinese Hamster Ovary 세포에서 Albumin-erythropoietin의 생산시 Silkworm Gland Hydrolysate의 효과 (Effects of Silkworm Gland Hydrolysate on Albumin-erythropoietin Production in Transgenic Chinese Hamster Ovary Cells)

  • 최민호;차현명;김선미;최용수;김동일
    • KSBB Journal
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    • 제28권2호
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    • pp.86-91
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    • 2013
  • To date, various strategies have been studied to increase specific productivity in Chinese hamster ovary (CHO) cell cultures. Also, albumin-fusion platform is being applied to other important bioactive peptides with short half-lives. Here, we investigated the effects of silkworm gland hydrolysate (SGH) on the production of albumin-erythropoietin (Alb-EPO) in transgenic CHO cells. The viable cell density of CHO cells was increased by 13% in the medium containing 1 mg/mL SGH higher than in the control medium without SGH. In addition, the production of Alb-EPO was also 1.26- fold enhanced by reducing the early apoptosis of CHO cells. In conclusion, SGH could be used as a useful supplement for the enhancement of recombinant protein production.

Neutron activation analysis: Modelling studies to improve the neutron flux of Americium-Beryllium source

  • Didi, Abdessamad;Dadouch, Ahmed;Jai, Otman;Tajmouati, Jaouad;Bekkouri, Hassane El
    • Nuclear Engineering and Technology
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    • 제49권4호
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    • pp.787-791
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    • 2017
  • Americium-beryllium (Am-Be; n, ${\gamma}$) is a neutron emitting source used in various research fields such as chemistry, physics, geology, archaeology, medicine, and environmental monitoring, as well as in the forensic sciences. It is a mobile source of neutron activity (20 Ci), yielding a small thermal neutron flux that is water moderated. The aim of this study is to develop a model to increase the neutron thermal flux of a source such as Am-Be. This study achieved multiple advantageous results: primarily, it will help us perform neutron activation analysis. Next, it will give us the opportunity to produce radio-elements with short half-lives. Am-Be single and multisource (5 sources) experiments were performed within an irradiation facility with a paraffin moderator. The resulting models mainly increase the thermal neutron flux compared to the traditional method with water moderator.

Analysis of Living Noise in a Multi-unit Dwelling using Acoustic Simulation

  • Yang, Ginam;Ann, Joon-suk;Kim, Daewon;Kim, Gwang-Hee;Shin, Yoonseok
    • 한국건축시공학회지
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    • 제16권1호
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    • pp.87-96
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    • 2016
  • More than half of Korea's urban population currently lives in multi-unit dwellings. This particular residence structure inevitably positions the living spaces of residents in close proximity to one another. Because of this proximity, the sounds of a particular household will transfer to other residents' units creating conflict between tenants. Efforts to alleviate this problem have been made in both the public and private sector. A prominent method of noise analysis between living units has been to make an actual sound measurement and obtain qualitative measurements from questionnaires. Although this method has been most widely used, such analysis requires a large amount of human effort and time. In addition, the questionnaire method fails to provide the objective information needed to accurately assess the noise situation. To overcome the inadequacies of this previous method, this study seeks to evaluate the applicability of an acoustic simulation method. Three types of living noises were analyzed to assess the noise levels passed between multi-unit dwellings. The acoustic simulation method was found to be more economical, efficient, and adaptable in information processing. The results of this study can be further applied to design and control living-noise through procedures such as acoustic absorption or space redesign.

ESTIMATION OF ALUMINUM AND ARGON ACTIVATION SOURCES IN THE HANARO COOLANT

  • Jun, Byung-Jin;Lee, Byung-Chul;Kim, Myung-Seop
    • Nuclear Engineering and Technology
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    • 제42권4호
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    • pp.434-441
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    • 2010
  • The activation products of aluminum and argon are key radionuclides for operational and environmental radiological safety during the normal operation of open-tank-in-pool type research reactors using aluminum-clad fuels. Their activities measured in the primary coolant and pool surface water of HANARO have been consistent. We estimated their sources from the measured activities and then compared these values with their production rates obtained by a core calculation. For each aluminum activation product, an equivalent aluminum thickness (EAT) in which its production rate is identical to its release rate into the coolant is determined. For the argon activation calculation, the saturated argon concentration in the water at the temperature of the pool surface is assumed. The EATs are 5680, 266 and 1.2 nm, respectively, for Na-24, Mg-27 and Al-28, which are much larger than the flight lengths of the respective recoil nuclides. These values coincide with the water solubility levels and with the half-lives. The EAT for Na-24 is similar to the average oxide layer thickness (OLT) of fuel cladding as well; hence, the majority of them in the oxide layer may be released to the coolant. However, while the average OLT clearly increases with the fuel burn-up during an operation cycle, its effect on the pool-top radiation is not distinguishable. The source of Ar-41 is in good agreement with the calculated reaction rate of Ar-40 dissolved in the coolant.

ROLE OF SOILS IN THE DISPOSAL OF NUCLEAR WASTE

  • Lee, S.Y.
    • 한국토양비료학회지
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    • 제19권3호
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    • pp.251-268
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    • 1986
  • Selecting a site for the safe disposal of radioactive waste requires the evaluation of a wide range of geologic, mineralogic, hydrologic, and physicochemical properties. Although highly diverse, these properties are in fact interrelated. Site requirements are also diverse because they are influenced by the nature of the radionuclides in the waste, for example, their half-lives, specific energy, and chemistry. A fundamental consideration in site selection is the mineralogy of the host rock, and one of the most ubiquitous mineral groups is clay minerals. Clays and clay minerals as in situ lithologic components and engineered barriers may playa significant role in retarding the migration of radionuclides. Their high sorptivity, longevity (stability), low permeability, and other physical factors should make them a very effective retainer of most radionuclides in nuclear wastes. There are, however, some unanswered questions. For example, how will their longevity and physicochemical properties be influenced by such factors as radionuclide concentration, radiation intensity, elevated temperatures, changes in redox condition, pH, and formation fluids for extended periods of time? Understanding of mechanisms affecting clay mineral-radionuclide interactions under prevailing geochemical conditions is important; however, the utilization of experimental geochemical information related to physicochemical properties of clays and clay-bearing materials with geohydrologic models presents a uniquely challenging problem in that many assessments have to be based on model predictions rather than on experiments. These are high-priority research investigations that need to be addressed before complete reliance for disposal area performance is made on clays and clay minerals.

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Preliminary Modelling of Plasco Tower Collapse

  • Yarlagadda, Tejeswar;Hajiloo, Hamzeh;Jiang, Liming;Green, Mark;Usmani, Asif
    • 국제초고층학회논문집
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    • 제7권4호
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    • pp.397-408
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    • 2018
  • In a recent tragic fire incident, the Plasco Tower collapsed after an intense outburst of fire lasting for three and a half hours and claiming the lives of 16 firefighters and 6 civilians. This paper will present continuing collaborative work between Hong Kong Polytechnic University and Queen's University in Canada to model the progressive collapse of the tower. The fire started at the 10th floor and was observed to have travelled along the floor horizontally and through the staircase and windows vertically. Plasco Tower was steel structure and all the steel sections were fabricated by welding standard European channel or angle profiles and no fire protection was applied. Four internal columns carried the loads transferred by the primary beams, and box columns were constructed along the perimeter of the building as a braced tube for resisting seismic loading. OpenSees fibre-based sections and displacement-based beam-column elements are used to model the frames, while shell elements are used for the reinforced concrete floor slabs. The thermal properties and elevated temperature mechanical properties are as recommended in the Eurocodes. The results in this preliminarily analysis are based on rough estimations of the structure's configuration. The ongoing work looks at modeling the Plasco Tower based on the most accurate findings from reviewing many photographs and collected data.

Nb 첨가 오스테나이트계 내열 스테인리스강의 열기계적 피로 수명 및 변형 거동 (Endurance Life and Deformation Behavior under Thermo-mechanical Fatigue of Nb-added Heat Resistant Austenitic Stainless Steel)

  • 오용준;박중철;양원존
    • 대한금속재료학회지
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    • 제49권7호
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    • pp.541-548
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    • 2011
  • Thermomechanical fatigue (TMF) behavior of heat resistant austenitic stainless steel was evaluated in the temperature range from 100$^{\circ}C$ to peak temperatures of 600 to 800$^{\circ}C$; The fatigue lives under TMF conditions were plotted against the plastic strain range and the dissipated energy per cycle. In the expression of the inelastic strain range versus fatigue life, the TMF data obtained at different temperature ranges were located close to a single line with a small deviation; however, when the dissipated energy per cycle, calculated from the area of the stress-strain hysteresis loops at the half of the fatigue life, was plotted against the fatigue life, the data showed greater scattering than the TMF life against the inelastic strain range. A noticeable stress relaxation in the stress-strain hysteresis curve took place at the peak temperatures higher than 700$^{\circ}C$, but all specimens in this study exhibited cyclic hardening behavior with TMF cycles. Recrystallization occurred during the TMF cycle concurrent with the formation of fine subgrains in the recrystallized region, which is considered to cause the cyclic hardening of the steel.

Impacts of Climate Change and Financial Support on Household Livelihoods: Evidence from the Northwest Sub-Region of Vietnam

  • DO, Thi Thu Hien;NGUYEN, Thi Lan Anh;NGUYEN, Thi Hoai Phuong
    • The Journal of Asian Finance, Economics and Business
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    • 제9권6호
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    • pp.115-126
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    • 2022
  • The study's goal is to determine the amount of climate change's impact on ethnic minority (EM) households' livelihoods, as well as their adaptability to climate change and long-term viability. The research was conducted in Vietnam's Northwestern Sub-region, where ethnic minorities account for more than half of the overall population. The study uses a combination of qualitative and quantitative methods based on a survey of 480 households in 04 provinces severely affected by climate change in the Northwest sub-region of Vietnam. The results show that: climate change (extreme weather events) occurs with increasing frequency, mainly affecting the life expectancy, health, and capital of households; Vulnerable groups (women, ethnic minorities) have a poor adaptive capacity and mainly suffer the consequences of shocks, are afraid to change their livelihoods; Microfinance plays an important role in enhancing the sustainability of livelihoods through increasing capital and financial assets and reducing the vulnerability of ethnic minority households. Finally, research has some solutions for microfinance - special credit specifically for ethnic minority households in the Northwest Sub-region: support for microfinance advice, home credit with transition orientations to adapt to climate change response and relieves its impact on the social lives.

Radioiodine internal dose coefficients specific for Koreans

  • Tae-Eun Kwon;Yoonsun Chung;Choonsik Lee
    • Nuclear Engineering and Technology
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    • 제56권7호
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    • pp.2732-2739
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    • 2024
  • This study developed internal dose coefficients for radioiodine, tailored to the Korean population, by incorporating the Korean biokinetic model along with the Korean S values. The observed differences in dose coefficients for Koreans compared to the International Commission on Radiological Protection (ICRP) reference values noticeably varied depending on physical half-lives of iodine isotopes. For longer-lived isotopes such as I-125 and I-129, significant differences in thyroid dose coefficients were observed, with ratios (Korean/ICRP) from 0.30 to 0.55, indicating that actual doses for Koreans can be considerably lower than those evaluated based on the ICRP data. However, for short-lived iodine isotopes, such as I-131, the thyroid dose coefficients were comparable to the ICRP reference values (ratio = 0.95-0.98). These comparable dose coefficients resulted from the lower thyroidal iodine uptake in the Korean model being almost entirely offset by the higher thyroid self-absorption S values in the Korean phantoms. Additionally, this study delves into the substantial differences in absorbed dose coefficients for non-thyroidal regions and effective dose coefficients, which arose not only from physiological/anatomical variability but also technical differences in phantom design. The use of Korean-specific dose coefficients is advisable particularly in scenarios predicting elevated doses, yielding a more precise and clinically relevant dose assessment.