• Archives of Craniofacial Surgery
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• v.21 no.1
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• pp.35-40
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• 2020

Background: Extensive eyelid defects are extremely challenging to reconstruct. Although numerous procedures for reconstructing periorbital defects have been proposed, no method is universally used. However, the Tenzel flap is the most commonly used technique to reconstruct eyelid defects affecting one-third to two-thirds of the eyelid. Methods: Recognizing the usefulness of the Tenzel method, we adapted it to reconstruct larger defects around the eyes. Seven patients underwent reconstruction with a modified Tenzel flap with an extended concept after wide excision of a malignant skin lesion. The main difference from the conventional method is that the modified Tenzel flap includes the medial portion of the lower lid defect. The design of a modified Tenzel flap begins as a semicircle at the lateral canthal area, in the same way as a classical Tenzel flap, and extends medially along the subciliary line to cover the defect on the medial lower eyelid. The follow-up time ranged from 3 to 28 months. Results: All flaps survived and healed well, with minimal scarring and natural palpebral outlines. Conclusion: Compared to traditional procedures, the modified Tenzel flap has several advantages, including a one-stage operation, a less noticeable scar, and effective prevention of complications such as lower eyelid ectropion.

• Journal of Korean Medicine Rehabilitation
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• v.27 no.3
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• pp.1-12
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• 2017

Objectives The purpose of this research is to investigate recent clinical treatment of Traditional Chinese Medicine for Compression Fracture. Methods We searched recent clinical studies about Oriental Medicine treatment in traditional chinese medical journals for Compression Fracture through China National Knowledge Infrastructure (CNKI). Clinical articles published from 2012 to 2016 were analyzed. This study examined the authors, published years, types of study, number of sample, criteria for evaluation, periods, purposes of study and classified articles by techniques of treatment. Results 23 papers were selected from 98 studies. Most of articles were classified as RCT. The techniques of treatment were herb medicine, herb medicine apply therapy, herb medicine fumigation therapy, Dao yin exercise. Conclusions Various and valuable studies about treatment of Compression fracture performed in chinese medicine. And more studies using various treatment needed for Korean Medicine development.

• Korean Journal of Biological Psychiatry
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• v.23 no.1
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• pp.18-23
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• 2016

Depression is a complicated psychiatric illness with severe consequences. Despite recent advanced achievements of molecular neurobiology, pathophysiology of depression has not been well elucidated. Among new findings of pathophysiology of depression, the possible fast antidepressant effect by N-methyl-D-asparate receptor antagonist, such as ketamine, is regarded as a promising treatment target of depression. Ketamine stimulates the mammalian target of rapamycin (mTOR) signaling pathway and activation of mTOR signaling pathway may be a key mechanism of the antidepressant effect of ketamine. Thus, this review describes the role of mTOR signaling in the pathophysiology of depression and developing a new treatment target of depression.

• Clinical and Experimental Pediatrics
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• v.59 no.sup1
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• pp.29-31
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• 2016

Glucose transport 1 (GLUT-1) deficiency is a rare syndrome caused by mutations in the glucose transporter 1 gene (SLC2A1) and is characterized by early-onset intractable epilepsy, delayed development, and movement disorder. De novo mutations and several hot spots in N34, G91, R126, R153, and R333 of exons 2, 3, 4, and 8 of SLC2A1 are associated with this condition. Seizures, one of the main clinical features of GLUT-1 deficiency, usually develop during infancy. Most patients experience brief and subtle myoclonic jerk and focal seizures that evolve into a mixture of different types of seizures, such as generalized tonic-clonic, absence, myoclonic, and complex partial seizures. Here, we describe the case of a patient with GLUT-1 deficiency who developed infantile spasms and showed delayed development at 6 months of age. She had intractable epilepsy despite receiving aggressive antiepileptic drug therapy, and underwent a metabolic workup. Cerebrospinal fluid (CSF) examination showed CSF-glucose-to-blood-glucose ratio of 0.38, with a normal lactate level. Bidirectional sequencing of SLC2A1 identified a missense mutation (c.1198C>T) at codon 400 (p.Arg400Cys) of exon 9.

• Journal of Korean Society for Geospatial Information Science
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• v.17 no.2
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• pp.3-9
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• 2009

These days, the value of the limited land rises in the city according to the increase of the population and the industrial development. And various studies on estimating the land price have been accomplished for the purpose of using the land efficiently. As a result, the officially assessed land price system was arranged. However the system is insufficient to reflect realities. Therefore, in this study, we examined the spatial distribution of the land price by joining spatially the officially assessed land price of Haeundae-gu, Busan from 2004 to 2008 to the map of lot number. We also computed and compared the change rate of the land price for 5 years. And we analyzed the relation between factors including the distance from the subway station, the land use and the land category which have an effect on the officially assessed land price and it using GIS technology.

• Annals of Clinical Neurophysiology
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• v.19 no.1
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• pp.20-27
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• 2017

Background: We evaluated whether eye movements could reflect the efficacy of antiepileptic drugs in patients with epilepsy. Methods: Thirty patients with epilepsy of unknown cause as well as age- and sex-matched normal controls were enrolled in this study. We divided the patients into drug-controlled epilepsy (n = 22) and drug-resistant epilepsy (n = 8) groups according to their seizure controls. We analyzed the differences in the parameters of the eye movements in these two groups compared with normal controls using video-based electro-oculography. In addition, we investigated the differences in the cerebellar volumes of these two groups using whole-brain T1-weighted images. Results: The latency and accuracy of saccade in patients with epilepsy were significantly different from normal controls, but they were not different between patients with drug-controlled epilepsy and drug-resistant epilepsy. However, the gain of pursuit was significantly decreased in patients with drug-resistant epilepsy compared with normal controls (p = 0.0010), whereas it was not different between patients with drug-controlled epilepsy and normal controls (p = 0.9646). In addition, the patients with drug-resistant epilepsy had lower cerebellar volumes than normal controls (p = 0.0052), whereas the cerebellar volumes in patients with drug-controlled epilepsy were not different from normal controls (p = 0.5050). Conclusions: We demonstrated that pursuit eye movements could reflect the efficacy of antiepileptic drugs in patients with epilepsy, a finding that may be related to cerebellar dysfunction.

• Advances in pediatric surgery
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• v.20 no.2
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• pp.65-68
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• 2014

Congenital duodenal obstruction is a one of the emergent surgical conditions in neonates. Almost of them were diagnosed with double-bubble sign in prenatal ultrasonography. However, partial obstruction caused from duodenal web could be overlooked. We reported a duodenal web in early childhood. A three-year-old girl visited at our pediatric clinic for constipation. She had been showed non-bilious vomiting after weaning meal since 6 months old of her age, but her weight was relevant for 50-75 percentile of growth curve. Barium enema was initially checked, but any abnormal finding was not found. We noticed the severely distended stomach and 1st portion of duodenum. Upper gastrointestinal series revealed partial obstruction in 2nd portion of duodenum. After laparotomy, we found the transitional zone of duodenum and identified a duodenal web via duodenotomy. We performed duodeno-duodenostomy without any injury of ampulla of Vater. She was recovered uneventfully. During 6 months after operation, she does well without any gastrointestinal symptoms or signs, such as vomiting or constipation.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.6 no.2
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• pp.150-156
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• 1994

Shoreline change due to the littoral drift in Suyeong bay, especially the Gwanganri and Haeundae beaches, was investigated. Average monthly frequency. speed. and direction of winds blowing from between east and south for the last 15 years were analysed, and offshore significant waves were hindcasted using the JONSWAP model. Wave refractions, shoaling, and breaking weir also investigated for the calculation of littoral drift. At the Gwanganri beach major longshore transport of sands occurs from the southwest to the northeast and the shoreline seems to advance in the northeast while it recedes in the southwest. At the Haeundae beach the sands mainly move from the east to the west and the shoreline retreats in the east and advances in the west.

• Journal of the Korean Solar Energy Society
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• v.28 no.2
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• pp.19-27
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• 2008

This study aims at examining the correlation between air temperature and urban structure such as land cover. For this, it measured summer air temperature by using data log type thermometer installed the inside of instrument screen, in the 9 points of elementary school in Haeundae, Busan. The accomplished results of this study are followings. 1) As altitude goes up 100m, air temperature drops to $0.6{\sim}1.0^{\circ}C$. 2) As building coverage ratio increases 10%, air temperature increases $0.3{\sim}0.4^{\circ}C$. 3) As floor space index increases 100%, air temperature increases $0.4{\sim}0.5^{\circ}C$. 4) As artificial coverage ratio increases 10%, air temperature increases $0.1{\sim}0.2^{\circ}C$. 5) As natural coverage ratio increases 10%, air temperature decreases $0.1{\sim}0.2^{\circ}C$.

• Journal of Fisheries and Marine Sciences Education
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• v.23 no.1
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• pp.1-12
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• 2011

The purpose of this study was to examine the effects of inferential reading strategy program on text comprehension and Korean language academic achievements of vocational high school students. We developed the program of inferential reading strategy, applied it to an educational spot, and examined the effects of it on text comprehension ability and Korean language academic achievements of learners. ANCOVA was used for data analysis with SPSS ver.12.0 statistic program. The main findings of this study were as follows. First, the experimental group which had been conducted with the inferential reading strategy program showed statistically significant difference in their text comprehension ability from controlled group. Second, the experimental group showed statistically significant difference in their Korean language academic achievements ability from controlled group. The study shows that the inferential reading strategy program had effect on the text comprehension and Korean language academic achievements of vocational high school students.