• Composites Research
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• v.15 no.1
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• pp.1-8
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• 2002

In this study, the flutter analysis for a rectangular box wing and an actual fighter wing with composite shin, aluminum spar and aluminum rib has been conducted. A conservative 3D wing-box model of an actual wing is modeled by MSC/PATRAN and the corresponding free vibration analysis has been performed by MSC/NASTRAN. The finite elements of membrane, rod and shear panel are used. Using the practical ply angles, various composite laminates are composed and analysed. The DLM code which is linear aerodynamic theory in frequency domain is applied to calculate unsteady aerodynamic pressure in subsonic flow region and the V-g and p-k methods are applied to obtain the solution of aeroelastic governing equation in frequency domain.

• Proceedings of the KSRS Conference
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• 2005.10a
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• pp.593-596
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• 2005

The MSC is a remote sensing instrument with very high performance that is to be installed on KOMPSAT2 satellite. The MSC consists of EOS (Electro-Optic Subsystem), PMU (Payload Management Unit) and PDTS (Payload Data Transmission Subsystem). PMU controls and monitors all the other payload units by sending commands and collecting telemetry. PMU is in charge of interfacing between payload system and satellite bus system. PMU gets commands from ground-station via OBC (On-Board Computer) that is a main controller of the satellite bus system and sends telemetry to the ground-station via OBC. There is a processor module, called SBC (Single Board Computer) in the PMU. The SBC is a main controller of the MSC system. The main roles of the SBC are payload mission management, command validation and execution, telemetry collection and monitoring, ancillary data handling, event reporting, power control of payload sub-units and communication with these units. Intel's 80486DX2 processor has been used for the SBC. Due to the fact that the SBC plays important roles for imaging mission execution and handles a lot of control data that is required for payload operation, it is required to make analysis of the CPU load when it is in maximum operation mode. In this paper, the analysis and measurement results of the SBC throughput in the maximum operation mode.

• International Journal of Stem Cells
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• v.11 no.2
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• pp.177-186
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• 2018

Background and Objectives: Glial scarring and inflammation after spinal cord injury (SCI) interfere with neural regeneration and functional recovery due to the inhibitory microenvironment of the injured spinal cord. Stem cell transplantation can improve functional recovery in experimental models of SCI, but many obstacles to clinical application remain due to concerns regarding the effectiveness and safety of stem cell transplantation for SCI patients. In this study, we investigated the effects of transplantation of human mesenchymal stem cells (hMSCs) that were genetically modified to express Olig2 in a rat model of SCI. Methods: Bone marrow-derived hMSCs were genetically modified to express Olig2 and transplanted one week after the induction of contusive SCI in a rat model. Spinal cords were harvested 7 weeks after transplantation. Results: Transplantation of Olig2-expressing hMSCs significantly improved functional recovery in a rat model of contusive SCI model compared to the control hMSC-transplanted group. Transplantation of Olig2-expressing hMSCs also attenuated glial scar formation in spinal cord lesions. Immunohistochemical analysis showed that transplanted Olig2-expressing hMSCs were partially differentiated into Olig1-positive oligodendrocyte-like cells in spinal cords. Furthermore, NF-M-positive axons were more abundant in the Olig2-expressing hMSC-transplanted group than in the control hMSC-transplanted group. Conclusions: We suggest that Olig2-expressing hMSCs are a safe and optimal cell source for treating SCI.

• Asian-Australasian Journal of Animal Sciences
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• v.26 no.4
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• pp.588-595
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• 2013

Mesenchymal stem cells (MSCs) are often known to have a therapeutic potential in the cell-mediated repair for fatal or incurable diseases. In this study, canine umbilical cord MSCs (cUC-MSCs) were isolated from umbilical cord matrix (n = 3) and subjected to proliferative culture for 5 consecutive passages. The cells at each passage were characterized for multipotent MSC properties such as proliferation kinetics, expression patterns of MSC surface markers and self-renewal associated markers, and chondrogenic differentiation. In results, the proliferation of the cells as determined by the cumulative population doubling level was observed at its peak on passage 3 and stopped after passage 5, whereas cell doubling time dramatically increased after passage 4. Expression of MSC surface markers (CD44, CD54, CD61, CD80, CD90 and Flk-1), molecule (HMGA2) and pluripotent markers (sox2, nanog) associated with self-renewal was negatively correlated with the number of passages. However, MSC surface marker (CD105) and pluripotent marker (Oct3/4) decreased with increasing the number of subpassage. cUC-MSCs at passage 1 to 5 underwent chondrogenesis under specific culture conditions, but percentage of chondrogenic differentiation decreased with increasing the number of subpassage. Collectively, the present study suggested that sequential subpassage could affect multipotent properties of cUC-MSCs and needs to be addressed before clinical applications.

• Proceedings of the Korean Institute of Surface Engineering Conference
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• 2018.06a
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• pp.33.1-33.1
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• 2018

pH is expressed mathematically as $pH=-{\log}[H^+]$, is a measure of the hydrogen ion concentration, [$H^+$] to specify the acidity or basicity of an aqueous solution. The pH scale usually ranges from 0 to 14. Every aqueous solution can be measured to determine its pH value. The pH values below 7.0 express the acidity, above 7.0 are alkalinity and pH 7.0 is a neutral solution. The solution pH can be determined by indicator or by measurement using pH sensor, which measuring the voltage generated between a glass electrode and a reference electrode according to the Nernst Equation. The pH value of solutions depends on the temperature and the activity of contained ions. In nickel electroless plating process, the controlled pH value in some limited ranges are extremely important to achieve optimal deposition rate, phosphorus content as well as solution stability. Basically, nickel electroless plating solution contains of $Ni^{2+}ions$, reducing agent, buffer and complexing agents. The plating processes are normally carried out at $82-92^{\circ}C$. However, the change of its pH values with temperatures does not follow any rule. Thus, the purpose of study is to understand the relationship between pH and temperature of some based solutions and electroless nickel plating solutions. The change of pH with changing temperatures is explained by view of the thermal dynamic and the practical measurements.

• Proceedings of the KSRS Conference
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• v.1
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• pp.212-215
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• 2006

This paper describes several reliability models to estimate COMS ground segment availability and shows assessed availability according to GS function. Due to a back-up concept among three ground center, SOC will have all H/W and S/W module to be installed in MSC and KOSC site. Therefore, all configurations and availability parameters for H/W and S/W modules in MSC and KOSC are assumed as equal with those in SOC, if related modules have same function. Prior to access availability over COMS GS function, Availability related to fundamental configuration such as series, parallel, partial operation, and module combined H/W and S/W is described. Consequently, all functions are expected to operate with more than 99% of availability.

• Proceedings of the KSRS Conference
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• 2007.03a
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• pp.308-310
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• 2007

복사 보정에 해당하는 NUC(Non-Uniformity Correction)은 MSC 각각의 픽셀들이 가지는 상이한 특성을 균일한 이미지를 얻기 위해 보정하는 작업으로서 KOMPSAT-2 검보정 작업 중 Video Processor 의 Electrical Gain/Offset 의 보정 과 더 불어 매 우 중요한 비중을 차지하는 과정이다. 본 논문에서는 KOMPSAT-2 의 Panchromatic 밴드의 raw image 를 이 용한 NUC 보정 작업 의 과정과 그 결과에 대해서 소개하고자 한다.

• Korean Chemical Engineering Research
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• v.55 no.5
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• pp.652-659
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• 2017

In the present research, in order to predict activity coefficient of inorganic ions in electrolyte solution of a petroleum system, we studied 13 components in the electrolyte solution, including $H_2O$, $CO_2$ (aq), $H^+$, $Na^+$, $Ba^{2+}$, $Ca^{2+}$, $Sr^{2+}$, $Mg^{2+}$, $SO_4$, $CO_3$, $OH^-$, $Cl^-$, and $HCO_3$. To predict the activity coefficient of the components of the petroleum system (a solid/liquid equilibrium system), activity coefficient model of Extended UNIQUAC was studied, along with its adjustable parameters optimized based on a genetic algorithm. The total calculated error associated with optimizing the adjustable parameters of Extended UNIQUAC model considering the 13 components under study at three temperature levels (298.15, 323.15, and 373.15 K) using the genetic algorithm is found to be 0.07.

• Journal of Powder Materials
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• v.21 no.1
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• pp.7-15
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• 2014

This study investigated the densification behavior of rhenium alloys including W-25 wt.%Re and Re-2W-1Ta (pure Re) during sintering. The dilatometry experiments were carried out to obtain the in-situ shrinkage in $H_2$ atmosphere. The measured data was analyzed through shrinkage, strain rate and relative density, and then symmetrically treated to construct the linearized form of master sintering curve (MSC) and MSC as a well-known and straightforward approach to describe the densification behavior during sintering. The densification behaviors for each material were analyzed in many respects including apparent activation energy, densification parameter, and densification ratio. MSC with a minimal set of preliminary experiments can make the densification behavior to be characterized and predicted as well as provide guideline to sinter cycle design. Considering the results of linearized form and MSC, it was confirmed that the W-25 wt.%Re compared to Pure Re is more easily densified at the relatively low temperature.

• IMMUNE NETWORK
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• v.23 no.6
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• pp.48.1-48.21
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• 2023

Mesenchymal stromal/stem cells (MSCs) possess immunoregulatory properties and their regulatory functions represent a potential therapy for acute lung injury (ALI). However, uncertainties remain with respect to defining MSCs-derived immunomodulatory pathways. Therefore, this study aimed to investigate the mechanism underlying the enhanced effect of human recombinant bone morphogenic protein-2 (rhBMP-2) primed ES-MSCs (MSC^BMP2) in promoting Tregs in ALI mice. MSC were preconditioned with 100 ng/ml rhBMP-2 for 24 h, and then administrated to mice by intravenous injection after intratracheal injection of 1 mg/kg LPS. Treating MSCs with rhBMP-2 significantly increased cellular proliferation and migration, and cytokines array reveled that cytokines release by MSC^BMP2 were associated with migration and growth. MSC^BMP2 ameliorated LPS induced lung injury and reduced myeloperoxidase activity and permeability in mice exposed to LPS. Levels of inducible nitric oxide synthase were decreased while levels of total glutathione and superoxide dismutase activity were further increased via inhibition of phosphorylated STAT1 in ALI mice treated with MSC^BMP2. MSC^BMP2 treatment increased the protein level of IDO1, indicating an increase in Treg cells, and Foxp3⁺CD25⁺ Treg of CD4⁺ cells were further increased in ALI mice treated with MSC^BMP2. In co-culture assays with MSCs and RAW264.7 cells, the protein level of IDO1 was further induced in MSC^BMP2. Additionally, cytokine release of IL-10 was enhanced while both IL-6 and TNF-α were further inhibited. In conclusion, these findings suggest that MSC^BMP2 has therapeutic potential to reduce massive inflammation of respiratory diseases by promoting Treg cells.