• 제목/요약/키워드: h-RN

검색결과 62건 처리시간 0.025초

Gas Exchange Rates Measured Using a Dual-Tracer ($SF_6$ and $^3He$) Method in the Coastal Waters of Korea

  • Lee, Hyun-Woo;Lee, Ki-Tack;Kaown, Duk-In
    • Ocean Science Journal
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    • 제43권1호
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    • pp.17-24
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    • 2008
  • Over a period of 5 days between August 12 and 17, 2005, we performed a gas exchange experiment using the dual tracer method in a tidal coastal ocean located off the southern coast of Korea. The gas exchange rate was determined from temporal changes in the ratio of $^3He$ to $SF_6$ measured daily in the surface mixed layer. The measured gas exchange rate($k_{CO_2}$), normalized to a Schmidt number of 600 for $CO_2$ in fresh water at $20^{\circ}C$, was approximately $5.0\;cm\;h^{-1}$ at a mean wind speed of $3.9\;ms^{-1}$ during the study period. This value is significantly less than those obtained from floating chamber-based experiments performed previously in estuarine environments, but is similar in magnitude to values obtained using the dual tracer method in river and tidal coastal waters and values predicted on the basis of the relationship between the gas exchange rate and wind speed (Wanninkhof 1992), which is generally applicable to the open ocean. Our result is also consistent with the relationship of Raymond and Cole (2001), which was derived from experiments carried out in estuarine environments using $^{222}Rn$ and chlorofluorocarbons along with measurements undertaken in the Hudson River, Canada, using $SF_6$ and $^3He$. Our results indicate that tidal action in a microtidal region did not discernibly enhance the measured $k_{CO_2}$ value.

Effect of black chokeberry on skeletal muscle damage and neuronal cell death

  • Kim, Jisu;Lee, Kang Pa;Beak, Suji;Kang, Hye Ra;Kim, Yong Kyun;Lim, Kiwon
    • 운동영양학회지
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    • 제23권4호
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    • pp.26-31
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    • 2019
  • [Purpose] Numerous epidemiological studies have shown that it is possible to prescribe exercise for neurodegenerative disease, such as Alzheimer's disease and Parkinson's disease. However, despite the availability of diverse scientific knowledge, the effects of exercise in this regard are still unclear. Therefore, this study attempted to investigate a substance, such as black chokeberry (Aronia melanocapa L.) that could improve the ability of the treatment and enhance the benefits of exercising in neurodegenerative diseases. [Methods] The cell viability was tested with 2,3-bis[2-methyloxy-4-nitro-5-sulfophenyl]-2H-tetrazolim-5-carboxanilide and the cells were stained with ethidium homodimer-1 solution. The mRNA expression levels were evaluated by microarray. The active compounds of black chokeberry ethanolic extract (BCE) were analyzed by gas chromatography. The chemical shift analysis in the brain was performed using magnetic resonance spectroscopy. [Results] BCE treatment decreased hydrogen peroxide-induced L6 cell death and beta amyloid induced primary neuronal cell death. Furthermore, BCE treatment significantly reduced the mRNA levels of the inflammatory factors, such as IL-1α, Cxcl13, IL36rn, Itgb2, Epha2, Slamf8, Itgb6, Kdm6b, Acvr1, Cd6, Adora3, Cd27, Gata3, Tnfrsf25, Cd40lg, Clec10a, and Slc11a1, in the primary neuronal cells. Next, we identified 16 active compounds from BCE, including D-mannitol. In vivo, BCE (administered orally at a dosage of 50 mg/kg) significantly regulated chemical shift in the brain. [Conclusion] Our findings suggest that BCE can serve as a candidate for neurodegenerative disease therapy owing to its cyto-protective and anti-inflammatory effects. Therefore, BCE treatment is expected to prevent damage to the muscles and neurons of the athletes who continue high intensity exercise. In future studies, it would be necessary to elucidate the effects of combined BCE intake and exercise.

배양대뇌신경세포 저산소증모델에서 유해산소생성억제 및 사립체막전위 소실방지에 의한 반하(半夏)의 신경세포사 억제 효능 (Neuroprotective Effects of Pinelliae Rhizoma Water-Extract by Suppression of Reactive Oxygen Species and Mitochondrial Membrane Potential Loss in a Hypoxic Model of Cultured Rat Cortical Cells.)

  • 권건록;문일수;이원철
    • 생명과학회지
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    • 제19권5호
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    • pp.598-606
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    • 2009
  • 본 연구는 저산소증에서 반하가 대뇌신경세포에 미치는 영향을 알아보기 위하여 $E_18$의 배양 흰쥐 대뇌신경세포를 반하로 전처리한 후, LDH assay와 tryphan blue 염색으로 세포 생존율을 측정하였고, $H_2DCF-DA$, JC-1 염색으로 MMP, ROS 및 RNS 변화를 조사하였다. 이에 반하는 저산소증으로 유발된 대뇌신경세포를 2.5 ${\mu}g/ml$까지 농도의존적으로 세포 생존률을 증가시켰으며, 시간에 따른 생존율을 살펴보면 저산소증 유발 후 1 시간에는 별 차이를 보이지 않았지만 3 일, 5 일 후에는 각각 10.2%, 17.8%로 매우 유의한 증가를 보였다. 저산소증에서 반하가 MMP에 미치는 영향을 보기 위해 저산소증 유발직전과 유발 후 1 일, 3 일, 5 일에 JC-1으로 염색하고 미토콘드리아의 염색강도를 측정한 결과 적색형광은 실험군에서 전반적으로 대조군에 비하여 강하게 염색되는 미토콘드리아의 비율을 증가시킨 반면 녹색형광은 대조군과 뚜렷한 차이를 보이지 않았다. 즉 반하가 저산소증으로 유발된 MMP의 소실을 감소시킴을 알 수 있다. 또한 반하는 전반적으로 $H_2DCF-DA$에 염색되는 세포 비율을 현저하게 낮추는 것으로 나타나 저산소증으로 유발된 ROS 및 RNS의 생성을 유의성 있게 감소시켰다. 따라서 반하는 저산소증에서 ROS의 생성을 억제하고 MMP의 소실을 막아 세포의 에너지고갈을 방지함으로서 신경세포를 보호하는 것으로 이해된다.

A Study on the Seasonal Comparison of Dry Matter Intake, Digestibility, Nitrogen Balance and Feeding Behavior in Spotted Deer (Cervus nippon) Fed Forest By-products Silage and Corn Silage

  • Moon, S.H.;Jeon, B.T.;Kang, S.K.;Sung, S.H.;Hudson, R.J.
    • Asian-Australasian Journal of Animal Sciences
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    • 제17권1호
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    • pp.80-85
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    • 2004
  • The purpose of this experiment was to assess seasonal variation of feed utilization by feed sources and to obtain information on the use of feed resources by comparing seasonal changes of dry matter intake, digestibility, nitrogen balance and feeding behavior in spotted deer (Cervus nippon) fed forest by-product silage (FBS) and corn silage (CS). Dry matter intake (DMI) of FBS was higher than that of CS in both winter and summer. While DMI of both diets was higher in summer, this was not significant at the 5% level. In contrast to DMI, digestible dry matter intake (DDMI) was higher for CS than for FBS in both seasons, but the difference was not significant. Digestibility of dry matter and crude protein was significantly higher (p<0.01) for CS than for FBS, whereas digestibility of crude fiber was significantly higher (p<0.01) for FBS than for CS in both seasons. Seasonal digestibility of dry matter and crude fiber for FBS was significantly greater (p<0.01) in summer than in winter: In summer, seasonal digestibility was 57.2% for dry matter and 55.5% for crude fiber, and in winter, 50.8% for dry matter and 30.7% for crude fiber. On the other hand, seasonal digestibility of crude protein was higher (p<0.01) in winter (42.1%) than in summer (32.3%). No significant difference (p>0.05) was found between the two seasons and diets for nitrogen intake (NI), 18.7 g/d in summer and 19.4 g/d in winter for FBS, 17.7 g/d in summer and 17.7 g/d in winter for CS. Fecal nitrogen was higher (p<0.01) for FBS than for CS and varied little seasonally. There was significant difference (p<0.01) between two seasons in urinary nitrogen, which was little difference between two diets. Retained nitrogen (RN) was different significantly (p<0.01) between two diets in both seasons, but there was little difference between seasons. Deer usually spent longer time on eating FBS than eating CS. Eating FBS took 221 min in summer and 187 min in winter, whereas eating CS took 113 min in summer and 109 min in winter. Deer spent less time on eating food in winter than in summer. Time spent on rumination was longer for FBS than for CS: for FBS, 504 min in summer and 456 min in winter, for CS, 423 min in summer and 279 min in winter. Time varied seasonally with both diets.

한국대학생(韓國大學生)의 Sodium과 Potassium섭취량(攝取量) 및 대사(代謝)에 관(關)한 연구(硏究) (A Study on the Sodium and Potassium Intakes and Their Metabolism of University Students in Korea)

  • 박태선;이기열
    • Journal of Nutrition and Health
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    • 제18권3호
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    • pp.201-208
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    • 1985
  • 본 연구에서는 한국인 남녀 대학생 집단의 1인 1일 Sodium(Na) 및 Potassium(K)섭취량을 뇨 성상분석과 식이 조사방법에 의해 평가하고 이들과 혈압 및 기타 요인들과의 상관성 유무를 검토하였다. 조사 결과를 요약해 보면 다음과 같다. 1) 1일 뇨중의 Na 배설량은 남자 대학생의 경우 199.1mEq(11.63g NaCl), 여자 대학생의 경우 174.5mEq(10.21g NaCl)이었고 식이 조사법에 의해 산출된 1인 1일 Na 섭취량은 남녀 각기 218.5mEq(12.77g NaCl), 218.1mEq(12.75g NaCl)로 나타났다. 2) 1일 뇨중의 K 배설량은 남자 대학생이 48.3 rnEq(1889mg), 여자 대학생이 43.9mEq(1,772mg)로 추정되었고, 식이 조사법에 의한 1인 1 일 K 섭취량은 남녀 각기 48.6mEq(1,897mg), 47.4mEq(1,850mg)인 것으로 나타났다. 3) 뇨중 Na/K 비을은 남자 대학생이 $4.67{\pm}2.42$, 여자 대학생이 $4.58{\pm}2.22$로 나타나 평균 $4.62{\pm}2.3$이었다. 4) 1일 총 뇨량은 남자 대학생의경우 1,228ml$($677ml/m^{2}/24hr$), 여자 대학생의 경우 1,116m1$($703ml/m^{2}/24hr$)$인 것으로 나타났다. 5) 뇨중 Na 및 K 배설량, Na/K비율과 혈압간에는 상관 관계가 존재하지 않았다. 이상의 뇨 분석 결과와 식이 조사결과를 종합해 본다면 이전의 동일 연령의 한국인을 대상으로 한 보고에 비해 서울지역 대학생 집단의 Na 섭취량이 현저히 감소된 반면, K 섭취량은 증가하여 Na/K 비율이 크게 감소하였고, 또한 Na 섭취량의 감소로 인한 1일 뇨 부피의 감소가 있었다. 그러나 아직도 미국인에 비해 Na 섭취량은 높고 K 섭취량은 낮아 Na/K비율이 높은 경향에 있다고 보겠다.

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한국 근해에 있어서의 중층 트로올의 연구 - II . 어구의 수평 전개도 - (Study on the Midwater Trawl Available in the Korean Waters - II . Horizontal Opening of the Gear -)

  • 이병기
    • 수산해양기술연구
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    • 제22권4호
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    • pp.49-55
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    • 1986
  • The authors carried out an experiment to determine the horizontal opening of the mid water trawl gear, which is the same as was used in the foreward experiment concerned to the attitude and opening efficiency of otter board. The trawl net .used in the experiment was designed to have a square sectional four-seamed body with two three-sepenlted wings. Each wing tip was rigged with a net pendant of 70 m long and the fore ends of the pendants were directly jointed to the otter pendant without inserting hand rope, and a front weight of 200 kg weigh was rigged with in front of the lowest wing tip. To determine the opening between otter boards ani between wing tips, two 50 KHz fish finders were set sideways on the otter board and on the port middle wing tip so as to detect the distance froa the finders to the starboard otter board and to the wing tip respectively, and the informations were transmitted to the indicators onboard the ship through water-tight cables. The results obtained can be summarized as follows: 1. The openings between otter borads were 43-45 m in case of the warp 100 m, 53-55 m in the war;> 150 m and 54-59 m in the warp 200 m. It was increased in linear according to the increase of towin; speed in the range of 1. 1-1. 8 mlscc. 2. The determined values of the openings between otter boards were greater than the estimated values. which were calculated by the opening between warps at the gallows of the ship and the length of tt~ warp, assuming that the warps from the top rollers to the otter boards were straight. The rates of the determined values to the estimated values were 1. 23-11. 0 in case of the warp 100 m, 1. 23-1. 12 in the warp 150 m and 1. 23-1. 15 in the warp 200 m respectively. The rates were almost the same at the slow towing speed of 1. 3 mlscc or so, then the higher the speed, the less the rate, and the longer the warp, the greater the rate. 3. The rates of the openings between otter boards to the total length of net pendant and the net (excluded cod end) showed 43-43% in case of the warp 150-200 m. It was a little smaller than th~ standard. which is 50%. in the common bottom trawl. 4. The determined openings between wing tips were 18-19 m in case of the warp 100m, 21-22 m in the warp 150 rn, They showed that the higher the speed, the greater the openings even though its range was no more than 1 m or so. 5. The rates of openings between otter boards to th~ openings betwee:l wing tips were almost invariably 38%. 6. The rates of openigs b2tween otter boards to the lenth of h~ad rope were 60-65% in cas': of th~ warp lOa-150m. It were much larg2r than th~ standard. which is 50%. in the common botto:n trawl.

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인산석고 취급공정에서의 라돈농도 및 유효선량 수준 평가 (Evaluation of Effective Dose and Exposure Level of Radon in Process Handling NORM)

  • 정은교;장재길;김종규;김준범;권지운
    • 한국산업보건학회지
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    • 제28권3호
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    • pp.283-291
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    • 2018
  • Objectives: To monitor the radon concentration level in plants that handle phosphorus rock and produce gypsum board and cement, and evaluate the effective dose considering the effect of radon exposure on the human body. Methods: Airborne radon concentrations were measured using alpha-track radon detectors (${\alpha}$-track, Rn-tech Co., Korea) and continuous monitors (Radon Sentinel 1030, Sun Nuclear Co., USA). Radon concentrations in the air were converted to radon doses using the following equation to evaluate the human effects due to radon. H (mSv/yr) = Radon gas concentration x Equilibrium factor x Occupancy factor x Dose conversion factor. The International Commission on Radiological Protection (ICRP) used $8nSv/(Bq{\cdot}hr/m^3)$ as the dose conversion factor in 2010, but raised it by a factor of four to $33nSv/(Bq{\cdot}hr/m^3)$ in 2017. Results: Radon concentrations and effective doses in fertilizer manufacturing process averaged $14.3(2.7)Bq/m^3$ ($2.0-551.3Bq/m^3$), 0.11-0.54 m㏜/yr depending on the advisory authority and recommendation year, respectively. Radon concentrations in the gypsum-board manufacturing process averaged $14.9Bq/m^3$ at material storage, $11.4Bq/m^3$ at burnability, $8.1Bq/m^3$ at mixing, $10.0Bq/m^3$ at forming, $8.9Bq/m^3$ at drying, $14.7Bq/m^3$ at cutting, and $10.5Bq/m^3$ at shipment. It was low because it did not use phosphate gypsum. Radon concentrations and effective doses in the cement manufacturing process were $23.2Bq/m^3$ in the stowage area, $20.2Bq/m^3$ in the hopper, $16.8Bq/m^3$ in the feeder and $11.9Bq/m^3$ in the cement mill, marking 0.12-0.63 m㏜/yr, respectively. Conclusions: Workers handling phosphorous gypsum directly or indirectly can be assessed as exposed to an annual average radon dose of 0.16 to 2.04 mSv or 0.010 to 0.102 WLM (Working Level Month).

계절에 따른 습지 내 저서성대형무척추동물 모니터링을 통한 지하수의존생태계 특성 평가 (Seasonal Assessment of Groundwater-Dependent Ecosystem Using Monitoring of Benthic Macroinvertebrates in Wetland)

  • 정찬영;최지웅;문희선;김동훈;문상호;오용화;한지연;오설란;김용철
    • 한국지하수토양환경학회지:지하수토양환경
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    • 제26권6호
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    • pp.130-143
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    • 2021
  • Wetlands are one of the most representative groundwater dependent ecosystems(GDEs) that require access to groundwater on a permanent or intermittent basis to maintain their biological communities and ecological processes. In this study, the seasonal characteristics of the GDEs in Baekseok Reservoir Wetland were evaluated through the monitoring of the temporal and spatial community of benthic macroinvertebrates in the wetland. The appearance of benthic macroinvertebrates appearance was changed seasonally depending on environmental factors such temperature, precipitation and water level for their habitat and it also showed the clear spatial difference in the wetland. The scores of Diversity index(H'), Richness Index (R1) and the Ecological score of benthic macroinvertebrates (TESB/AESB) were relatively high at St.3 and 4(i.e., north area) where groundwater inflows into wetland(i.e., high 222Rn conc.). The statistical analysis (ANOVA test and PCA) investigated the correlation among the benthic macroinvertebrates' community, groundwater level, wetland water level and water quality. The results showed that the community of benthic macroinvertebrates at St. 3 and 4 in Baekseok Reservoir Wetlands was spatially dependent on groundwater level and groundwater inflow. The characterization and assessment of GDEs requires understanding the hydrological, biogeochemical and biological process and this study will provide information for characterization and assessment of GDEs.

대전지역 시험용 시추공 지하수내 우라늄 및 라돈-222의 지화학적 산출특성 (Geochemical Occurrence of Uranium and Radon-222 in Groundwater at Test Borehole Site in the Daejeon area)

  • 정찬호;유근석;김문수;김태승;한진석;조병욱
    • 지질공학
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    • 제23권2호
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    • pp.171-186
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    • 2013
  • 본 연구는 대전지역 기존 지하수중 우라늄 및 라돈-222와 같은 자연방사성 물질의 농도가 높은 것으로 알려진 한 지점을 선정하여 121 m 심도의 연구용 시추공을 확보하여 심도별 지하수내 우라늄 및 라돈-222의 산출특성 밝히고, 시추코어를 이용하여 우라늄의 기원에 대한 지화학적 상관성을 알아보고자 하였다. 이를 위하여 더블패커를 이용하여 시추공내 심도별로 6개 지하수 시료를 채취하여 화학성분 분석, 우라늄과 라돈-222의 함량을 분석하였다. 분석결과 지하수의 pH는 중성내지는 알카리성이며, 화학성분상 $Ca-HCO_3(SO_4+Cl)$ 유형에 속한다. 그리고 우라늄과 라돈-222의 농도는 각각 169~1,020 ppb와 $9,190{\pm}96{\sim}32,800{\pm}180$ pCi/L를 보여 심도별 뚜렷한 농도차이를 보이며, 모두 미국 EPA 권고치를 초과하였다. 지하수내 우라늄은 지하 45~50m 심도에서 가장 높은 함량을 보인다. 이 구간 지하수는 약알카리성의 산환환경이며 높은 $HCO_3$의 함량으로 우라늄 용존에 유리한 환경으로 보인다. 지하수내 우라늄의 형태는 우라닐탄산염화합물{$(UO_2CO_3)^0$ 혹은 $(UO_2HCO_3)^+$}이 우세한 것으로 보인다. 라돈-222 함량은 심도가 깊어질수록 증가하는 경향을 보인다. 시추코어에 의한 지질주상도특성을 보면 모암은 복운모화강암이며 페그마타이트가 수 곳에서 확인되었고, 중성질 암맥이 100 m 내외에서 확인되었다. 암석내 우라늄과 토륨의 함량은 0.372~47.4 ppm과 0.388~11.2 ppm의 범위를 보여 기존 국내에서 보고된 함량보다 높은 값을 보인다. 암석현미경 관찰 및 전자현미분석결과 방사성원소를 함유하는 광물로는 장석과 흑운모내 포획된 모자나이트, 인회석, 녹염석 광물로 확인되었으며, 광물내 주요성분을 치환하여 주로 존재한다.

동력경운기의 경사지견인 및 주행특성에 관한 연구 (III)-동력경운의 경사지 견인성능- (Study on the Travel and Tractive Characteristics of the Two-Wheel Tractor on the General Slope Land(III)-Tractive Performance of Power Tiller-)

  • 송현갑;정창주
    • Journal of Biosystems Engineering
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    • 제3권2호
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    • pp.35-61
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    • 1978
  • 동력경운깅가 일반 경사지에서 견인주행하는 경우 견인주행성능과 주행특성을 구명하기 위하여 토양의 종류 및 상태는 일정하게 하고 지면의 기하학적 조건과 견인주행속도 및 견인하중을 변수로 하여 외부동력전달계의 시점인 좌우차륜과 토양간에 발생하는 차륜구동력 및 굴름정항과 Engine에서 구동륜까지 내부전달계를 통하여 전달된 동력의 이론치와 실험치와의 부합여부를 검정하고 부가적으로 동력경운기가 경사지기계화의 동력기로써의 가능성여부와 문제점을 찾으려한다.

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