• Journal of Power System Engineering
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• v.17 no.2
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• pp.56-62
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• 2013

A technique is presented that uses a circular waveguide for the measurement of the bulk shear (S-wave) velocities of unconsolidated, saturated media, with particular application to near surface soils. The technique requires the measurement of the attenuation characteristics of the fundamental torsional mode that propagate along an embedded pipe, from which the acoustic properties of the surrounding medium are inferred. From the dispersion curve analysis, the feasibility of using fundamental torsional mode which is non-dispersive and have constant attenuation over all frequency range is discussed. The principles behind the technique are discussed and the results of an experimental laboratory validation are presented. The experimental data are best fitted for the different depths of wetted sand and the shear velocities are evaluated as a function of depths. Also the characteristics of the reflected signal from the defects are examined and the reflection coefficients are calculated for identifying the relation between defect sizes and the magnitude of the reflected signal.

• Proceedings of the Korean Geotechical Society Conference
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• 2005.03a
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• pp.328-337
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• 2005

This work reports results of our study on the dynamic responses of the buried pipelines both along the axial and the transverse directions under various boundary end conditions. We have considered three cases, i.e., the free ends, the fixed ends, and the fixed-free ends for the axial direction, and three more cases including the guided ends, the simply supported ends, and the supported-guided ends for the transverse direction. In order to investigate the effect of the boundary end conditions for the dynamic responses of the buried pipeline, we have devised a computer program to find the solutions of the formulae on the dynamic responses (displacements, axial strains, and bending strains) under the various boundary end conditions considered in this study. The dynamic behavior of the buried pipelines for the forced vibration is found to exhibit two different forms, a transient response and a steady state response, depending on the time before and after the transfer of a seismic wave on the end of the buried pipeline. The former is identified by a slight change in its behavior before the sinusoidal-shaped seismic wave travels along the whole length of the pipeline whereas the latter by the complete form of a sinusoidal wave when the wave travels throughout the pipeline. The transient response becomes insignificant as the wave speed increases. We have observed a resonance when the mode wavelength matches the wavelength of the seismic wave, where the mode number(k) of resonance for the axial direction is found to be $\overline{\omega}/{\pi}V+1/2$ for the fixed-free ends, $\overline{\omega}/{\pi}V+1$ for the free ends, and $\overline{\omega}/{\pi}V$ for the fixed ends, respectively. By adding 10 more modes to the mode number(k) of resonance, we were able to study all the dynamic responses of the buried pipeline for the axial direction. On the other hand, we have not been able to observe a resonance in the analysis for the transverse direction, because the dynamic responses are found to vanish after the seventh mode. From the results of the dynamic responses at the many points of the pipeline, we have found that the responses appeared to be dependent critically on the boundary end conditions. Such effects are found to be most prominent especially for the maximum values of the displacement and the strain and its position.

• Journal of the Korean Society for Nondestructive Testing
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• v.24 no.1
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• pp.15-21
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• 2004

It is possible to detect flaws in pipelines without interruption using all EMAT transducer because it is a non-contact transducer which can transmit ultrasonic waves into specimens without couplant. And it ran easily generate guided waves desired in each specific problem by altering the design of coil and magnet. In the present work, EMAT systems have been fabricated to generate surface waves, and selectively the plate wave of $A_1\;or\;S_1$ mode. The surface wave of 1.5MHz showed a good signal-to-noise ratio without distortion in its propagation along a pipeline, while the $S_1$ mode of 800kHz and the $A_1$ mode of 940kHz were distorted according to their dispersive properties. The wider the excitation pulse becomes, the better the mode selectivity of the plate waves becomes. A pipe of 256mm inner diameter and 5.5m thickness with 5 flaws was used for comparing the flaw detectability among the modes under consideration.

• Journal of the Korean Society for Nondestructive Testing
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• v.28 no.6
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• pp.512-518
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• 2008

Guided wave technology is advantageous for fast inspection of pipe wall thinning since the guided wave propagates long distance. In this investigation, the method to evaluate gradual wall thinning in a pipe based on the arrival time delay with magnetostrictive patch transducers is presented. Low frequency A0 Lamb waves were generated and measured by the present transducer and it was applied to arrival time delay measurement experiments on a test pipe having gradual wall thinnings artificially manufactured. From experiments, consistent results that wall thinning increases the arrival time delay of A0 waves were obtained. Consequently, the feasibility of the magnetostrictive patch transducers to evaluate wall thinning was verified.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.66 no.9
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• pp.1341-1350
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• 2017

In this paper, a high reliability 30W DC-DC converter is designed considering military standard (MIL-STD) for military applications such as guided weapon and aircraft. The performances and specifications of conventional military grade DC-DC converter are practically analyzed. The requirements for military grade DC-DC converter are established in consideration of MIL-STD and analysis results of conventional product. Two isolated DC-DC converter, forward and fly-back converter, are designed and compared to determine topology. From experimental results under various operating conditions, the forward topology satisfied performances and specifications of MIL-STD for military DC-DC converter.

• Proceedings of the Korean Geotechical Society Conference
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• 2006.03a
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• pp.1340-1347
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• 2006

Dynamic response of buried pipelines both in the axial and the transverse directions on concrete pipe and steel pipe, FRP pipe were investigated through a free vibration analysis. End boundary conditions considered herein consist of free ends, fixed ends, and fixed-free ends in the axial and the transverse direction. Guided ends, simply supported ends, and supported-guided ends were added to the transverse direction. The buried pipeline was regarded as a beam on an elastic foundation and the ground displacement of sinusoidal wave was applied to it. Natural frequencies and mode shapes were determined according to end boundary conditions. In addition, the effects of parameters on the natural frequency were evaluated. The natural frequency is affected most significantly by the soil stiffness and the length of the buried pipelines. The natural frequency increases as the soil stiffness increases while it decreases as the length of the buried pipeline increases. Such behavior appears to be dominant in the axial direction rather than in the transverse direction of the buried pipelines.

• Journal of the Korean Institute of Telematics and Electronics A
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• v.31A no.5
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• pp.85-93
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• 1994

We have studied the effect of channel and/or spacing chirpings on the near field and near field intensity patterns, modal gains and radiation angles of 6 supermodes in the index-guided laser arrays with 6 channels, on the basis of the coupled mode theory. The spacings between channels can be indenpendent parameters for control of the radiation angle. It is found that an asymmetrically v channel-chirped array has both a smaller radiation angle and better supermode discrimination characteristics than a uniform array. Comparing two approaches for enhancing modal stability in point of supermode discrimination characteristics, approach I which increases the coupling cofficient between the outer-most waveguides at each end of an otherwise uniform array, has superior discrimination characteristics to the approach II which increases the propagation constant for the end elements with the same coupling between neighbor elements. Approach III which has a narrower spacing between the outer-most waveguides at one end and a wider channel width of the outer-most waveguide at another end, gets a narrower radiation angle than the approach I and good supermode discrimination characteristics by applying optimized gain profiles.

• Korean Journal of Optics and Photonics
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• v.7 no.2
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• pp.150-156
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• 1996

RWG MQW-LD has been made with our vertical LPE system from the optimal design condition for the RWG MQW-LD to be activated as weakly index-guided LD. Through several experiments we have established the growth condition which can be used through to grow the MQW-DH wafer and to control the thickness of MQW layer to ~200$\AA$. 4 ${\mu}{\textrm}{m}$-thickness of the ridge pattern has been formed through the photolithographic process on the MQW-DH wafer grown by the former condition, and then we have fabricated the RWG MQW-LD using it. From the result of measuring the electro-optical characteristics we can make sure that it can be lasing as lasing as laterally single mode at even more than $2.7I_{th}$.

• Natural Product Sciences
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• v.27 no.2
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• pp.78-85
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• 2021

Through bio-guided isolation, two natural iron chelators were isolated from Mangifera indica L. leaves, identified as mangiferin (1) and iriflophenone-3-C-𝛽-D-glucoside (2). Their iron-chelating activity was compared to that of Desferal^® using bipyridyl assay and EDTA as a standard. Mangiferin showed the highest activity with IC₅₀ value of 0.385 mM (162.85 ㎍/mL). Furthermore, two combinations of mangiferin with Desferal^® (M-D) and iriflophenone-3-C-𝛽-D-glucoside (M-I) were evaluated. The results showed that mangiferin potentiated the iron chelation activity of Desferal^® about 46%, also that M-I combination is a promising candidate formula for iron chelation therapy. In addition, mangiferin and Desferal-iron complexes were prepared and characterized by IR, UV, and Mass spectra to compare their mode of chelation to iron. Their structural stability was studied by DFT calculations. Furthermore, they displayed increased ABTS antioxidant activity when bound to iron as compared to their free form, which enhances their pharmacological importance.

• Clinical and Experimental Pediatrics
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• v.65 no.5
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• pp.239-249
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• 2022

Cells survive and proliferate through complex interactions among diverse molecules across multiomics layers. Conventional experimental approaches for identifying these interactions have built a firm foundation for molecular biology, but their scalability is gradually becoming inadequate compared to the rapid accumulation of multiomics data measured by high-throughput technologies. Therefore, the need for data-driven computational modeling of interactions within cells has been highlighted in recent years. The complexity of multiomics interactions is primarily due to their nonlinearity. That is, their accurate modeling requires intricate conditional dependencies, synergies, or antagonisms between considered genes or proteins, which retard experimental validations. Artificial intelligence (AI) technologies, including deep learning models, are optimal choices for handling complex nonlinear relationships between features that are scalable and produce large amounts of data. Thus, they have great potential for modeling multiomics interactions. Although there exist many AI-driven models for computational biology applications, relatively few explicitly incorporate the prior knowledge within model architectures or training procedures. Such guidance of models by domain knowledge will greatly reduce the amount of data needed to train models and constrain their vast expressive powers to focus on the biologically relevant space. Therefore, it can enhance a model's interpretability, reduce spurious interactions, and prove its validity and utility. Thus, to facilitate further development of knowledge-guided AI technologies for the modeling of multiomics interactions, here we review representative bioinformatics applications of deep learning models for multiomics interactions developed to date by categorizing them by guidance mode.