• Journal of Gifted/Talented Education
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• v.26 no.4
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• pp.721-746
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• 2016

The purpose of this study was to investigate the effects of science experience with their children on mothers who have children who are science gifted children and how they perceive what kind of parenting methods are appropriate for the growth and development of children who are science gifted children. To do this, we interviewed 13 mothers of the gifted education center of the Ministry of Education and conducted two in - depth interviews with them. Results, mothers who have scientific gifted children have various science experiences with children who are scientific gifted. In this process, mothers of gifted children understand the gifted children through science experience with their children, I have come to realize that it is necessary to provide an educational environment that can express my child's talents and help to determine the direction of my career. For this purpose, leadership education that reminds the importance of relationships between people, providing opportunities for various experiences so that they can decide their life, career education through inquiry of deep science experience and meeting with senior scientists, humanities for integrated thinking And the arts. In this way, it is possible to provide in-depth research results to the mothers of the gifted and talented to provide specific directions for the various supportive methods and teaching methods that the gifted children should provide for intellectual and emotional growth and development. Development of educational programs is necessary.

• Journal of the Korean Orthopaedic Association
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• v.52 no.1
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• pp.73-82
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• 2017

Purpose: To assess the chronological changes of disease-related kyphosis after chemotherapy alone. Materials and Methods: A total of 101 children aged 2 to 15 years with spinal tuberculosis, accompanied by various stages of disease processes were enrolled for analysis. By utilizing the images in them, the growth plate condition and chronological changes of kyphosis after chemotherapy were analyzed at two points in time; the first assessment was at post-chemotherapy one-year and second at the final discharge. Results: Complete disc destruction in the cervical, dorsal and lumbosacral spines was observed in 2 out of 40 children (5.0%), 8 out of 30 children (26.7%), and 6 out of 31 children (19.4%), respectively. In those cases, the residual kyphosis inevitably developed. In the remaining children, the discs were intact or partially damaged. Among the 101 children kyphotic deformity was maintained without change in 20 children (19.8%). Kyphosis decreased in 14 children (13.9%), while it increased in 67 children (66.3%) with non-recoverably damaged growth plate. Conclusion: Although it is tentatively possible to predict the deformity progress or non-progress and spontaneous correction at the time of the initial treatment, its predictive accuracy is low. Therefore, assessment of the chronological changes should be performed at the end of chemotherapy. In children with progressive curve change, assessment of deformity should be continued until maturity.

• Journal of the Korean Society of Costume
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• v.39
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• pp.139-166
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• 1998

This dissertation is to help understanding about the emergence of active children's clothes in the latter part of the 18th century in England. In previous ages children had not been look-ed upon as children, but as incomplete and in-ferior men and women, the costume of children had not been distinguishable from that of their elders. The early eighteenth-century chil-d could not play in comfort because they dressed like their parents. But in the third quarther of the eighteenth century children became free from their con-comfortable and became active. English chil-dren's clothes was prevailing even in Europe as well. In the background of this liberation, there were many enlightened ideas, such as philosophers of enlightenment, doctors, writers, educators. Among these John Locke and Jean Jacque Rousseau criticized openly about rampant fashion which was distorting the body by corset and hoop. Rousseau was the one who wrote$\boxDr$Emile$\boxUl$and played the most important role to free children from an old fashioned idea, and emphasized to bring up children by the natural process of mental and physical development as human beings are a part of nature. Fashion reflects politic, economic, social, ideology, culture of the days and these factor function to create fashion which shows“Time Spirit”.Children's clothes, like those of their parents, follow the fashion, but with a difference, the form of which varies with the attitude to the child. Thus this dissertation was to study in relation with the background of the times in the latter part of 18th century in England and Rousseau's Naturalism in connection with the emergence of active children's clothes. The result is that diffusion of the idea of freedom and equality, the growth of bourgeoisie, the development of clothing and tex-tile industry have influenced to the emergence of active children's clothes. Also a great deal of middle and high class parents devoted to their children's education and was influenced by Rousseau's Naturalism. Specially the bourgeoisie who made their fortune by their own effort were eager to educate their achievement and business by their children through education. This factor influenced to the children's clothes as well.

• Korean Journal of Community Nutrition
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• v.23 no.3
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• pp.216-225
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• 2018

Objectives: This study was conducted to investigate the associations between obesity and the children's Nutrition Quotient (NQ) and to further examine the relationships between NQ and mini dietary assessment (MDA) of their parents. Methods: The subjects were 355 children aged 3 to 5 years and their parents in Dongducheon. We collected parental-reported NQ questionnaires for children and MDA of parents. Anthropometric measurements, height, weight and BMI by BIA were measured in children. Overweight and obesity were determined according to age- and sex-specific BMI percentile from the 2007 Korean national growth chart. Statistical analyses consisted of the chi-squared test, ANOVA, partial correlations and logistic regression analysis adjustments for parents BMI. Results: Approximately 20.8% of preschool children were classified as overweight or obese. Underweight children showed a significantly higher score for balance than overweight children. The NQ of the children was $61.9{\pm}11.6$, and NQ scores and their parents' MDA did not exhibit any significant differences according to degree of obesity. After adjusting for parent's BMI, children's BMI was significantly correlated with balance and moderation among NQ factors. Parent's MDA showed significant correlation with their children's NQ, balance, diversity, moderation, regularity, practice and NQ grade, except for diversity of father. Additionally, NQ grade had a significantly increased (150.1%) odds ratio (OR) of being overweight (95% CI 1.008-2.234). Conclusions: These results show that NQ for children is influenced by their parents' MDA and BMI. Furthermore, our findings support the association between overweight prevention and improvement of NQ grade among preschool children.

• Annals of Pediatric Endocrinology and Metabolism
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• v.23 no.4
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• pp.176-181
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• 2018

Noonan syndrome (NS) is an autosomal dominant disorder that involves multiple organ systems, with short stature as the most common presentation (>70%). Possible mechanisms of short stature in NS include growth hormone (GH) deficiency, neurosecretory dysfunction, and GH resistance. Accordingly, GH therapy has been carried out for NS patients over the last three decades, and multiple studies have reported acceleration of growth velocity (GV) and increase of height standard deviation score (SDS) in both prepubertal and pubertal NS patients upon GH therapy. One year of GH therapy resulted in almost doubling of GV compared with baseline; afterwards, the increase in GV gradually decreased in the following years, showing that the effect of GH therapy wanes over time. After four years of GH therapy, ~70% of NS patients reached normal height considering their age and sex. Early initiation, long duration of GH therapy, and higher height SDS at the onset of puberty were associated with improved final height, whereas gender, dosage of GH, and the clinical severity did not show significant association with final height. Studies have reported no significant adverse events of GH therapy regarding progression of hypertrophic cardiomyopathy, alteration of metabolism, and tumor development. Therefore, GH therapy is effective for improving height and GV of NS patients; nevertheless, concerns on possible malignancy remains, which necessitates continuous monitoring of NS patients receiving GH therapy.

• The korean journal of orthodontics
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• v.17 no.2
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• pp.311-320
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• 1987

The purpose of this study was to investigate the growth changes of maxilla and mandible and position changes of first permanent molars of growing children The author analyzed the data using cephalometric roentgenogram of 43 boys and 39 girls age of 6 to 11 with normal occlusion The obtained results were as follows 1 The eruption path of maxillary and mandibular first permanent molar superimposed on TM-ANS and mandibular plane shows individual variation 2 There was no correlation between horizontal and vertical changes of maxillary first permanent molar, but positive correlation in mandibular first permanent molar 3 As the eruption, the forward changes of mandibular first permanent molar was significantly greater than that of maxillary first permanent molar 4 As the ages were increased, there were irregular growth changes of maxilla and mandible 5 Growth changes of lower anterior facial height was relatively stable 6 N-S-${\bar{6}}$ was stable after age 7.

• Clinical and Experimental Pediatrics
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• v.46 no.4
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• pp.363-369
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• 2003

Purpose : Pharmacologic provocation test of growth hormone(GH) is a non-physiologic method and has several limitations for diagnosing growth hormone(GH) deficiency. Spontaneous GH release studies could be important in understanding the pathophysiology of children with poor growth but normal responses to GH provocation tests. Also, the relationship between nocturnal GH secretions and sleep patterns in short stature children is poorly understood. The aim of this study is to determine whether there are differences in sleep patterns and nocturnal GH secretory profiles between idiopathic short stature children and a normal stature group. Methods : Spontaneous nocturnal GH secretions and sleep patterns were evaluated in 12 prepubertal idiopathic short stature children with normal responses to provocation tests and 9 normal stature controls. Blood samples were taken every 30 minutes from 22:00-06:30 and sleep patterns were analyzed by polysomnography. Results : The mean GH level during sleep was significantly lower in short stature children than in controls. The peak GH level after sleep, coincident with the first slow wave sleep, was lower in the short stature group. The slow wave sleep times of short stature children were decreased compared with those of normal subjects. Conclusion : These results suggest that overnight serial GH sampling is helpful to identify short stature children with subnormal GH secretions, and sleep structure differences may be associated with decreased overnight GH secretions in short stature children.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.22 no.5
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• pp.479-486
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• 2019

Progressive familial intrahepatic cholestasis (PFIC) is a group of severe genetic disorders, inherited in an autosomal recessive manner, causing cholestasis of hepatocellular origin, later progressing to biliary cirrhosis and liver failure. This is the first report of PFIC type 1 with novel compound heterozygous mutations in Korea. The patient was presented with intrahepatic cholestasis, a normal level of serum ${\gamma}-glutamyl$ transferase, steatorrhea, and growth failure. Genetic testing of this patient revealed novel compound heterozygous mutations (p.Glu585Ter and p.Leu749Pro) in the ATP8B1 gene. After a liver transplantation at age 19 months, the patient developed severe post-transplant steatohepatitis.

• Clinical and Experimental Pediatrics
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• v.64 no.8
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• pp.408-414
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• 2021

Background: Complementary food in infancy is necessary for human growth, neurodevelopment, and health. However, the role of allergen consumption in early infancy and its effects on the development of food allergy or tolerance remain unclear. Purpose: To investigate the influence of age at the time of complementary food introduction on the development of asthma and atopic dermatitis in Korean children aged 1-3 years. Methods: We combined data from the Korea National Health and Nutrition Examination Survey collected from 2010 to 2014 and analyzed 1619 children aged 1-3 years who were included in the survey. Multivariate regression analysis was used to identify associations among type of feeding, age at the time of complementary food introduction, and doctor-diagnosed atopic dermatitis and asthma. Results: Age at the time of complementary food introduction was not significantly associated with doctor-diagnosed atopic dermatitis and asthma in children aged 1-3 years. In the univariate analysis, children with asthma showed higher water and sodium intake levels than nonasthmatic children. However, this relationship was not significant in the multivariate regression analysis. Conclusion: The present study revealed no statistically significant relationship between age at the time of complementary food introduction and the risk of atopic dermatitis and asthma in young Korean children. A national prospective study is needed to clarify the influence of age at the time of complementary food introduction on the development of allergic diseases.

• Clinical and Experimental Pediatrics
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• v.55 no.7
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• pp.224-231
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• 2012

Prader-Willi syndrome (PWS) is a complex multisystem genetic disorder characterized by hypothalamic-pituitary dysfunction. The main clinical features include neonatal hypotonia, distinctive facial features, overall developmental delay, and poor growth in infancy, followed by overeating with severe obesity, short stature, and hypogonadism later in development. This paper reviews recent updates regarding the genetic aspects of this disorder. Three mechanisms (paternal deletion, maternal disomy, and deficient imprinting) are recognized. Maternal disomy can arise because of 4 possible mechanisms: trisomy rescue (TR), gamete complementation (GC), monosomy rescue (MR), and postfertilization mitotic nondisjunction (Mit). Recently, TR/GC caused by nondisjunction at maternal meiosis 1 has been identified increasingly, as a result of advanced maternal childbearing age in Korea. We verified that the d3 allele increases the responsiveness of the growth hormone (GH) receptor to endogenous GH. This paper also provides an overview of endocrine dysfunctions in children with PWS, including GH deficiency, obesity, sexual development, hypothyroidism, and adrenal insufficiency, as well as the effects of GH treatment. GH treatment coupled with a strictly controlled diet during early childhood may help to reduce obesity, improve neurodevelopment, and increase muscle mass. A more active approach to correct these hormone deficiencies would benefit patients with PWS.