• Clinical and Experimental Reproductive Medicine
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• 제27권4호
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• pp.381-385
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• 2000

Objective: To verify the effect of two forms (growth factor and growthfactor-reduced) of solubilized Matrigel on the development in mouse preimplantation embryos. Methods: Late 2-cell stage eggs were cultured through the blastocyst stage in the presence of GF- or GFR-Matrigel (0.5%, v/v). Morphological development, cell number and % apoptotic nuclei of blastocyst were measured by Roecst staining and TUNEL of nuclei. Results: Morphological development, number of cells per embryo was significantly increased in the presence of GF- or GFR-Matrigel. Culture of the embryos in the GF-Matrigel gave the best result. Conclusion: Low concentration of solubilized Matrigel improved development of mouse embryos regardless of growth factor content of the Matrigel. Growth factors and extracellular matrix protein included in the Matrigel synergistically potentiated the development of mouse embryos.

• 한국지역지리학회지
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• 제15권5호
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• pp.525-536
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• 2009

급속한 경제성장의 시기에는 요소투입에 의한 성장정책과 성장의 지역적 분배에 기초한 지역개발정책이 가능하였다. 그러나 국가간 경쟁이 심화되고 불확실성의 증대로 성장의 원동력이 크게 약화된 시기에 이러한 모델은 이론적, 실용적 권위를 잃고 있다. 세계화된 경쟁적 환경과 불확실한 세계경제 변화에 신속하고 효율적으로 대처할 수 있는 내생적인 지역혁신역량 구축이 성장과 지역개발정책의 새로운 대안으로 등장하였다. 중앙집권적인 성장정책과 지역개발정책으로 수도권의 과밀화와 지방의 과소화 문제를 겪었던 프랑스는 지방의 내생적인 혁신역량 구축을 위해 지난 1970년대부터 단계적인 지역혁신체계 구축 정책을 실행해 오고 있다. 지방의 내생적인 혁신역량 구축을 위해 계획적인 지식창출과 지역개발을 동시에 추구해온 프랑스의 지역혁신체계의 구축 수단과 방식은 지역의 내생적인 혁신역량 강화와 지역간 불균형 문제를 해소하려는 정부의 정책에 많은 시사점을 제공한다.

• East Asian Economic Review
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• 제19권1호
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• pp.39-70
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• 2015

This paper examines the effects of foreign direct investment (FDI) on South Asian economies' output growth, utilizing recent panel cointegration testing and estimation techniques. Annual panel data on eight SAARC (South Asian Association for Regional Cooperation) member countries' macroeconomic variables over the period 1960- 2013 are employed in empirical analysis. Using various heterogeneous panel cointegration and panel causality tests, a bi-directional relationship between FDI and growth is found. We find evidence for both FDI-led growth and growth-induced FDI hypotheses for the South Asian economies over the sample period. Individual member countries exhibit heterogeneity in terms of the direction or existence of causality subject to their idiosyncratic economic conditions. Among various regressors, FDI, financial development, human capital, and government consumption show the most significant positive effects on output growth. As determinants of FDI, GDP, financial development, human capital, and government consumption are found significant in the region. The bi-directional causality between FDI and growth is found robust to the inclusion of other control variables and using different estimation techniques.

• Molecules and Cells
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• 제41권4호
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• pp.257-263
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• 2018

Vertebrate organ development is accompanied by demarcation of tissue compartments, which grow coordinately with their neighbors. Hence, perturbing the coordinative growth of neighboring tissue compartments frequently results in organ malformation. The growth of tissue compartments is regulated by multiple intercellular and intracellular signaling pathways, including the Hippo signaling pathway that limits the growth of various organs. In the optic neuroepithelial continuum, which is partitioned into the retina, retinal pigment epithelium (RPE) and ciliary margin (CM) during eye development, the Hippo signaling activity operates differentially, as it does in many tissues. In this review, we summarize recent studies that have explored the relationship between the Hippo signaling pathway and growth of optic neuroepithelial compartments. We will focus particularly on the roles of a tumor suppressor, neurofibromin 2 (NF2), whose expression is not only dependent on compartment-specific transcription factors, but is also subject to regulation by a Hippo-Yap feedback signaling circuit.

• Journal of Plant Biology
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• 제27권4호
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• pp.241-251
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• 1984

The present study investigated the effects of triacontanol (TRIA) on plant growth and peroxisomal enzyme activities in radish seedlings. The optimum concentration of TRIA with respect to radish seedling bioassay was decided to 1.0mg $1^{-1}$. In comparison to untreated controls (including Tween 20 treatment), 1.0mg $1^{-1}$ TRIA treatment caused an increase in seed germination rate and root growth, but no stimulation in hypocotyl growth. Chlorophyll accumulation in cotyledon during carly development stage increased rapidly, and degradation of chlorophyll in later stage due to the cotyledon senesence was noticeably retarded. Increase of soluble protein content in cotyledon at early period of development was observed. Isocitrate lyase and catalase activity was not significantly different in both the treated and the untreated plants. But, glycolate oxidase activity was inhibited by TRIA down to 20% against controls. Also, the increase of the activity of peroxidase, a leaf-senescence marker enzyme, was continuously retarded over control for 8 days of development. Based on above results, TRIA was found to be active in both the growth and the peroxisomal enzyme activities of radish seedlings.

• World Technopolis Review
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• 제3권3호
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• pp.153-164
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• 2014

It is recent that STEM (Science, Technology, Engineering and Mathematics) education emerged as a great concern of the U.S. policy makers in terms of securing national and regional competitiveness. However, few attempts to embrace STEM education as a source for sustainable regional growth have been made mainly due to methodological challenges. This paper investigates the role of STEM education in achieving sustainable economic growth. For the purpose of the paper, a U.S. federal workforce development program named Workforce Innovation in Regional Economic Development (WIRED) in Southeastern Virginia that was implemented between 2007 and 2010 is selected and evaluated qualitatively. By identifying three themes as a result of three-stage coding methods, the evaluation results call for particular attention of local policy makers and key stakeholders to STEM education as a source of sustainable long-term economic growth in regions.

• 유통과학연구
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• 제20권11호
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• pp.79-88
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• 2022

Purpose: The purpose of this study was to determine the effect of agricultural exports and imports on economic growth in Bangladesh and propose an upgraded and customized model of the supply chain for agribusiness growth in Bangladesh to achieve plain sailing and systematic operation and financial gains at home and abroad. Research design, data, and methodology: All data in the research have been collected from secondary sources. Gross domestic product was used as the dependent variable and exports and imports of agricultural products were used as independent variables. Pairwise Granger causality was utilized to see the impact of the variable responsible for the economic growth in Bangladesh and the causal relationship between the variables analyzed was measured using Johansen co-integration test. Results: From the empirical analysis, the researchers observed that agricultural commodity imports and exports have a unidirectional impact on economic growth in Bangladesh and a long-run causal link with economic growth in Bangladesh. The suggested supply chain model of agribusiness aids in achieving smooth operations, systematic management, and monetary gains both domestically and internationally. Conclusions: This paper contributes to the development of a more effective and profitable agribusiness supply chain in Bangladesh systematically through their theoretical and practical implications.

• Asian-Australasian Journal of Animal Sciences
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• 제29권8호
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• pp.1065-1074
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• 2016

Growth factors play an important role during early ovarian development and folliculogenesis, since they regulate the migration of germ cells to the gonadal ridge. They also act on follicle recruitment, proliferation/atresia of granulosa cells and theca, steroidogenesis, oocyte maturation, ovulation and luteinization. Among the growth factors, the growth differentiation factor 9 (GDF9) and the bone morphogenetic protein 15 (BMP15), belong to the transforming growth factor beta (TGF-${\beta}$) superfamily, have been implicated as essential for follicular development. The GDF9 and BMP15 participate in the evolution of the primordial follicle to primary follicle and play an important role in the later stages of follicular development and maturation, increasing the steroidogenic acute regulatory protein expression, plasminogen activator and luteinizing hormone receptor (LHR). These factors are also involved in the interconnections between the oocyte and surrounding cumulus cells, where they regulate absorption of amino acids, glycolysis and biosynthesis of cholesterol cumulus cells. Even though the mode of action has not been fully established, in vitro observations indicate that the factors GDF9 and BMP15 stimulate the growth of ovarian follicles and proliferation of cumulus cells through the induction of mitosis in cells and granulosa and theca expression of genes linked to follicular maturation. Thus, seeking greater understanding of the action of these growth factors on the development of oocytes, the role of GDF9 and BMP15 in ovarian function is summarized in this brief review.

• 한국수산과학회지
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• 제44권6호
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• pp.695-700
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• 2011

Age, growth, and maturity of Trichiurus lepturus were estimated based on right-handed sagittal otoliths belonging to 1,031 fish collected from January to December 2007 in the East China Sea. The outer margins of the otolith were examined and showed that an opaque zone was formed once per year. Marginal increments in otoliths formed as annual rings between June and August, at the beginning of the spawning season. Fish growth was expressed by the von Bertalanffy growth equation, as follows: $L_t=494.0$ ($1-e^{-0.2453(t+-0.4822)}$) for females and $L_t=330.4$ ($1-e^{-0.4292(t+0.7513)}$) for males, where $L_t$ is the total length in mm and t is age in years. The growth rates of males and females were significantly different (P<0.05).The age composition ranged mostly between ages 2 and 4, and the oldest individuals were 4 years old in males and 6 years old in females. Finally, the age composition of largehead hairtail was compared with data from the 1970s and is discussed in the context of environmental changes.

• 품질경영학회지
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• 제47권1호
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• pp.187-198
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• 2019

Purpose: In this study, a reliability prediction based reliability growth management is suggested especially for the early development phase of a system and the case study of surveillance system is given. Methods: The proposed reliability prediction based reliability growth management procedures consists of 7 Steps. In Step 1, the stages for reliability growth management are classified according to the major design changes. From Step 2 to Step 5, system reliability is predicted based on reliability structures and the predicted reliabilities of subsystems (Level 2) and modules (Level 3). At each stage, by comparing the predicted system reliability with that of the previous stage, the reliability growth of the system is checked in Step 6. In Step 7, when the predicted value of sustem reliability does not satisfy the reliability goal, some design alternatives are considered and suggested to improve the system reliability. Results: The proposed reliability prediction based reliability growth management can be an efficient alternative for managing reliability growth of a system in its early development phase. The case study shows that it is applicable to weapon system such as a surveillance system. Conclusion: In this study, the procedures for a reliability prediction based reliability growth management are proposed to satisfy the reliability goal of the system efficiently. And it is expected that the use of the proposed procedures would reduce, in the test and evaluation phase, the number of corrective actions and its cost as well.